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Our top choices for Substance hotels

1. Circa Resort & Casino – Adults Only
Circa Resort & Casino – Adults OnlyDowntown Las Vegas, 0.5 km from Substance
9.4 out of 10, Exceptional, (5,662 reviews)
The price is 3.130.890 ₫
5.024.421 ₫ total
includes taxes & fees
16 Jun - 17 Jun

2. The ENGLISH Hotel, Las Vegas, a Tribute Portfolio Hotel, 21 and over
The ENGLISH Hotel, Las Vegas, a Tribute Portfolio Hotel, 21 and overArts District, 1.4 km from Substance
9.4 out of 10, Exceptional, (129 reviews)
The price is 3.051.960 ₫
3.448.714 ₫ total
includes taxes & fees
21 Jun - 22 Jun

3. Main Street Station Hotel, Casino and Brewery
Main Street Station Hotel, Casino and BreweryDowntown Las Vegas, 0.6 km from Substance
9.0 out of 10, Wonderful, (3,363 reviews)
The price is 644.858 ₫
1.709.527 ₫ total
includes taxes & fees
28 Jun - 29 Jun

4. Element by Marriott Las Vegas Symphony Park
Element by Marriott Las Vegas Symphony Park1.2 km from Substance
9.2 out of 10, Wonderful, (108 reviews)
The price is 2.929.618 ₫
3.968.218 ₫ total
includes taxes & fees
30 Jun - 1 Jul

5. Four Queens Hotel and Casino
Four Queens Hotel and CasinoDowntown Las Vegas, 0.3 km from Substance
8.6 out of 10, Excellent, (7,163 reviews)
The price is 1.552.290 ₫
1.754.087 ₫ total
includes taxes & fees
1 Jul - 2 Jul

6. Downtown Grand Las Vegas
Downtown Grand Las VegasDowntown Las Vegas, 0.2 km from Substance
8.4 out of 10, Very good, (10,028 reviews)
The price is 1.026.090 ₫
2.318.964 ₫ total
includes taxes & fees
15 Jun - 16 Jun

7. El Cortez Hotel and Casino - 21 and Over
El Cortez Hotel and Casino - 21 and OverDowntown Las Vegas, 0.2 km from Substance
8.4 out of 10, Very good, (7,249 reviews)
The price is 1.005.568 ₫
2.028.238 ₫ total
includes taxes & fees
13 Jul - 14 Jul

8. the D Las Vegas
the D Las VegasDowntown Las Vegas, 0.2 km from Substance
8.4 out of 10, Very good, (7,505 reviews)
The price is 762.990 ₫
2.049.812 ₫ total
includes taxes & fees
15 Jun - 16 Jun

9. AC Hotel by Marriott Las Vegas Symphony Park
AC Hotel by Marriott Las Vegas Symphony Park1.2 km from Substance
8.8 out of 10, Excellent, (218 reviews)
The price is 2.683.620 ₫
3.690.240 ₫ total
includes taxes & fees
5 Jul - 6 Jul

10. Hotel Apache
Hotel ApacheDowntown Las Vegas, 0.4 km from Substance
8.4 out of 10, Very good, (1,139 reviews)
The price is 1.014.094 ₫
1.145.926 ₫ total
includes taxes & fees
9 Jul - 10 Jul

11. Golden Nugget Las Vegas Hotel & Casino
Golden Nugget Las Vegas Hotel & CasinoDowntown Las Vegas, 0.4 km from Substance
8.2 out of 10, Very good, (13,507 reviews)
The price is 783.955 ₫
2.253.464 ₫ total
includes taxes & fees
16 Jun - 17 Jun

12. Plaza Hotel & Casino
Plaza Hotel & CasinoDowntown Las Vegas, 0.6 km from Substance
8.2 out of 10, Very good, (5,285 reviews)
The price is 805.086 ₫
2.069.229 ₫ total
includes taxes & fees
15 Jun - 16 Jun

13. Fremont Hotel & Casino
Fremont Hotel & CasinoDowntown Las Vegas, 0.3 km from Substance
8.8 out of 10, Excellent, (4,350 reviews)
The price is 674.851 ₫
1.773.148 ₫ total
includes taxes & fees
29 Jun - 30 Jun

14. Oasis at Gold Spike
Oasis at Gold SpikeDowntown Las Vegas, < 0.1 km from Substance
8.0 out of 10, Very good, (2,279 reviews)
The price is 923.481 ₫
1.638.139 ₫ total
includes taxes & fees
15 Jun - 16 Jun

15. Desert Moon Motel
Desert Moon MotelDowntown Las Vegas, 1.5 km from Substance
8.4 out of 10, Very good, (499 reviews)
The price is 1.452.733 ₫
1.641.588 ₫ total
includes taxes & fees
13 Jul - 14 Jul

16. Downtowner Boutique Hotel
Downtowner Boutique HotelDowntown Las Vegas, 0.4 km from Substance
7.6 out of 10, Good, (42 reviews)
The price is 805.086 ₫
1.504.354 ₫ total
includes taxes & fees
15 Jun - 16 Jun

17. Golden Gate Hotel and Casino
Golden Gate Hotel and CasinoDowntown Las Vegas, 0.5 km from Substance
7.6 out of 10, Good, (1,067 reviews)
The price is 631.440 ₫
1.901.160 ₫ total
includes taxes & fees
15 Jun - 16 Jun

18. Bposhtels Las Vegas
Bposhtels Las Vegas1.8 km from Substance
7.6 out of 10, Good, (293 reviews)
The price is 694.584 ₫
1.082.183 ₫ total
includes taxes & fees
16 Jun - 17 Jun

19. The STRAT Hotel, Casino & Tower
The STRAT Hotel, Casino & TowerLas Vegas Strip, 2.9 km from Substance
7.6 out of 10, Good, (23,510 reviews)
The price is 355.185 ₫
1.892.644 ₫ total
includes taxes & fees
15 Jun - 16 Jun

20. Thunderbird Hotel
Thunderbird HotelGateway District, 1.8 km from Substance
7.2 out of 10, Good, (1,003 reviews)
The price is 1.065.555 ₫
1.709.361 ₫ total
includes taxes & fees
15 Jun - 16 Jun
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels close to Substance
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
![]() Circa Resort & Casino – Adults Only | 9.4 Exceptional 5,662 reviews | View | ||||||
![]() The ENGLISH Hotel, Las Vegas, a Tribute Portfolio Hotel, 21 and over | 9.4 Exceptional 129 reviews | View | ||||||
![]() Main Street Station Hotel, Casino and Brewery | 9.0 Wonderful 3,363 reviews | View | ||||||
![]() Element by Marriott Las Vegas Symphony Park | 9.2 Wonderful 108 reviews | View | ||||||
![]() Four Queens Hotel and Casino | 8.6 Excellent 7,163 reviews | View |
Top Substance Hotel Reviews

SAHARA Las Vegas
10/10 Excellent










































































