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16 Dec - 17 Dec
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17 Dec - 18 Dec
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19 Dec - 21 Dec
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26 Dec - 28 Dec

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Our top choices for Tower Grove South hotels

Lobby
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis, 6.8 km from Tower Grove South
8.4 out of 10, Very good, (4016)
"Arch view room is big and comfortable fantastic. . "
United States
Tim
The price is 2.213.734 ₫
2.610.635 ₫ total
includes taxes & fees
29 Dec - 30 Dec
Hyatt Regency St. Louis at The Arch
Standard King Room with Whirlpool - Non Smoking | Desk, laptop workspace, blackout curtains, iron/ironing board
Quality Inn O'Fallon IL - St. Louis

Quality Inn O'Fallon IL - St. Louis

Quality Inn O'Fallon IL - St. Louis
3.0 star property
26.5 km from Tower Grove South
7.4 out of 10, Good, (1004)
"Bed was comfortable, room was quiet, breakfast had limited options and bathroom was tiny. Overall great value for the price! "
United States
Alison
The price is 1.205.090 ₫
1.385.613 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Quality Inn O'Fallon IL - St. Louis
Lobby
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
2.5 star property
18.7 km from Tower Grove South
9.4 out of 10, Exceptional, (2766)
"Friendly staff.. airport shuttle service excellent!!"
United States
Nancy and Ron
The price is 2.367.367 ₫
2.786.964 ₫ total
includes taxes & fees
20 Dec - 21 Dec
Pear Tree Inn St. Louis Airport
Lobby
Motel 6 Hazelwood, MO

Motel 6 Hazelwood, MO

Motel 6 Hazelwood, MO
2.0 star property
22.7 km from Tower Grove South
8.4 out of 10, Very good, (1618)
"great stay."
United States
Allison
The price is 1.504.497 ₫
1.839.122 ₫ total
includes taxes & fees
29 Dec - 30 Dec
Motel 6 Hazelwood, MO
Exterior
Best Western Plus St. Louis Airport Hotel

Best Western Plus St. Louis Airport Hotel

Best Western Plus St. Louis Airport Hotel
2.5 star property
17.6 km from Tower Grove South
9.2 out of 10, Wonderful, (1002)
"Room was nice and comfortable, pool was awesome, and breakfast left us all happy"
United States
Letez
Best Western Plus St. Louis Airport Hotel
Lobby sitting area
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
3.0 star property
24.8 km from Tower Grove South
7.4 out of 10, Good, (1003)
"Clean lobby, super friendly staff, effortless check in. There’s even a small market with food and essentials right next to the check in desk. "
United States
Jen
The price is 1.686.073 ₫
1.955.641 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
Lobby
Pear Tree Inn St. Louis Convention Center

Pear Tree Inn St. Louis Convention Center

Pear Tree Inn St. Louis Convention Center
3.0 star property
Downtown St. Louis, 7.1 km from Tower Grove South
9.0 out of 10, Wonderful, (1054)
"It was perfect for our stay in St. Louis to visit the arch."
United States
Jacob
The price is 2.472.595 ₫
2.891.139 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Pear Tree Inn St. Louis Convention Center
Bar (on property)
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis, 6.7 km from Tower Grove South
8.8 out of 10, Excellent, (1154)
"Really nice hotel!"
United States
DARIN
The price is 2.296.601 ₫
2.731.323 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Property amenity
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis, 6.7 km from Tower Grove South
9.4 out of 10, Exceptional, (3285)
"Our stay was very enjoyable. Location was great and kids loved the indoor pool!"
United States
Christy
The price is 3.551.182 ₫
4.152.361 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Drury Plaza Hotel St. Louis at the Arch
5 restaurants, breakfast, lunch, dinner served; American cuisine
River City Casino & Hotel

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
7.5 km from Tower Grove South
9.0 out of 10, Wonderful, (1449)
"Awesome place to stay!!"
United States
Kaitlyn
The price is 2.314.753 ₫
3.076.341 ₫ total
includes taxes & fees
24 Dec - 25 Dec
River City Casino & Hotel
Breakfast, dinner and brunch served
The Principal Hotel

The Principal Hotel

The Principal Hotel
3.5 star property
18 km from Tower Grove South
9.8 out of 10, Exceptional, (191)
"Great place. Very nice rooms, new and clean."
United States
Jeff
The price is 2.967.693 ₫
3.293.637 ₫ total
includes taxes & fees
24 Dec - 25 Dec
The Principal Hotel
Exterior
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay
3.5 star property
9 km from Tower Grove South
8.8 out of 10, Excellent, (3034)
"Clean room, good breakfast and good location "
United States
Martin
The price is 2.365.922 ₫
2.761.931 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Clayton Plaza Hotel & Extended Stay
Lobby
Hampton Inn St. Louis - Columbia

Hampton Inn St. Louis - Columbia

Hampton Inn St. Louis - Columbia
2.5 star property
17.6 km from Tower Grove South
8.6 out of 10, Excellent, (476)
"Breakfast was great and a very good atten"
United States
John
The price is 2.447.016 ₫
2.715.699 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Hampton Inn St. Louis - Columbia
Free daily buffet breakfast
Tru By Hilton St. Louis Downtown

Tru By Hilton St. Louis Downtown

Tru By Hilton St. Louis Downtown
2.5 star property
Downtown West, 6.4 km from Tower Grove South
7.6 out of 10, Good, (591)
"Breakfast was delicious and room was comfy "
United States
Ronnesha
The price is 2.135.602 ₫
2.497.138 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Tru By Hilton St. Louis Downtown
Lobby sitting area
Best Western Plus The Charles Hotel

Best Western Plus The Charles Hotel

Best Western Plus The Charles Hotel
3.0 star property
28.2 km from Tower Grove South
8.0 out of 10, Very good, (1008)
"The room is decent for a night. The price is great and hotel staff is friendly. "
United States
Jordan
The price is 2.291.866 ₫
2.656.744 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Best Western Plus The Charles Hotel
Lobby
Best Western Plus St. Louis West-Westport

Best Western Plus St. Louis West-Westport

Best Western Plus St. Louis West-Westport
2.5 star property
20.9 km from Tower Grove South
8.0 out of 10, Very good, (1033)
"The room was great and the bed was very comfortable "
United States
Joyce
The price is 2.213.734 ₫
2.567.665 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Best Western Plus St. Louis West-Westport
Reception
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
19.3 km from Tower Grove South
8.0 out of 10, Very good, (1042)
"Everything was clean and friendly staff overall good experience "
United States
dennis
The price is 2.236.520 ₫
2.583.312 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Exterior
Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis, 6.9 km from Tower Grove South
8.8 out of 10, Excellent, (1243)
"Great hospitality"
United States
Alejandro
The price is 2.820.110 ₫
3.353.929 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Embassy Suites by Hilton St. Louis Downtown
Lobby
Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles
3.0 star property
27.7 km from Tower Grove South
9.6 out of 10, Exceptional, (1004)
"Staff and hotel were amazing"
United States
Allison
The price is 3.025.042 ₫
3.506.723 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Drury Plaza Hotel St. Louis St. Charles
Lobby
Best Western St. Louis Inn

Best Western St. Louis Inn

Best Western St. Louis Inn
2.5 star property
17.9 km from Tower Grove South
8.0 out of 10, Very good, (1006)
"Good staff, smooth and welcome checkin"
United States
Amit
The price is 1.834.210 ₫
2.109.121 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Best Western St. Louis Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Tower Grove South

Find the best Tower Grove South areas for the activities you enjoy most.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Saint Louis Abbey while you're in town.

Central West End

Central West End

If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.

Top Tower Grove South Hotel Reviews

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Frequently asked questions

What's it like in Tower Grove South?
Travellers will be sure to find plenty to entertain them in St. Louis's Tower Grove South neighbourhood. Consider a visit to Cherokee Street as part of your Tower Grove South travel plans.
How many hotels will I find in the Tower Grove South area?
If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 39 Tower Grove South hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Tower Grove South, will I receive a refund?
Yes, the majority of hotel bookings are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of your booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to get the top deals on offer in Tower Grove South.
What is there to do in this St. Louis neighbourhood?
Cherokee Street is an attraction you might want to check out while you're in Tower Grove South. While you're out sightseeing in St. Louis, make sure that you visit other sights such as Tower Grove Tennis Center or Missouri Botanical Gardens and Arboretum.