Photo by Michelle Hendrix
Search Spa Hotels in Upstate South Carolina
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check availability on Upstate South Carolina Spa Hotels
Top Upstate South Carolina Spa Hotels

Hotel Hartness
Greenville
9.8 out of 10, Exceptional, (619)

Hotel Domestique
Travelers Rest
9.6 out of 10, Exceptional, (30)
The price is 10.783.285 ₫
11.861.614 ₫ total
includes taxes & fees
8 Dec - 9 Dec

Grand Bohemian Lodge Greenville, Autograph Collection
Greenville Downtown
9.6 out of 10, Exceptional, (411)
The price is 7.092.185 ₫
8.014.169 ₫ total
includes taxes & fees
30 Nov - 1 Dec

SKYLARANNA Resort & Spa
Hendersonville
8.2 out of 10, Very good, (340)
The price is 2.343.190 ₫
3.385.110 ₫ total
includes taxes & fees
1 Dec - 2 Dec

Echo Mountain Inn
Hendersonville
9.0 out of 10, Wonderful, (544)
The price is 3.001.655 ₫
3.384.365 ₫ total
includes taxes & fees
2 Dec - 3 Dec

Lake Lure Inn and Spa
Lake Lure
8.4 out of 10, Very good, (88)
The price is 2.525.503 ₫
2.854.011 ₫ total
includes taxes & fees
23 Dec - 24 Dec

1898 Waverly Inn
Hendersonville
9.4 out of 10, Exceptional, (290)
The price is 3.309.889 ₫
3.731.901 ₫ total
includes taxes & fees
30 Nov - 1 Dec

Greystone Inn
Lake Toxaway
9.4 out of 10, Exceptional, (85)
The price is 6.893.129 ₫
8.587.080 ₫ total
includes taxes & fees
1 Dec - 2 Dec
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Upstate South Carolina Hotel Reviews
Explore a world of travel with Expedia
Top areas for Spa Hotels
Nearby Cities
Choose Your Upstate South Carolina Hotel Style
- Business Hotels in Upstate South Carolina
- Cheap Hotels in Upstate South Carolina
- Family-Friendly Hotels in Upstate South Carolina
- Golf Hotels in Upstate South Carolina
- Historic Hotels in Upstate South Carolina
- Hotels Suites in Upstate South Carolina
- Hotels near Museums in Upstate South Carolina
- Hotels with Air Conditioning in Upstate South Carolina
- Hotels with Airport Transfers in Upstate South Carolina
- Hotels with Breakfast in Upstate South Carolina
- Hotels with Connecting Rooms in Upstate South Carolina
- Hotels with Entertainment in Upstate South Carolina
- Hotels with Gym in Upstate South Carolina
- Hotels with Hot Tubs in Upstate South Carolina
- Hotels with Indoor Pools in Upstate South Carolina
- Hotels with Laundry Service in Upstate South Carolina
- Hotels with Parking in Upstate South Carolina
- Hotels with Parking in Upstate South Carolina
- Hotels with Pool in Upstate South Carolina
- Hotels with Restaurant in Upstate South Carolina
- Hotels with Room Service in Upstate South Carolina
- Hotels with Wifi in Upstate South Carolina
- Hotels with a Bar in Upstate South Carolina
- Hotels with a View in Upstate South Carolina
- Hotels with smoking rooms in Upstate South Carolina
- Lakeside Hotels in Upstate South Carolina
- Luxury Hotels in Upstate South Carolina
- Pet-Friendly Hotels in Upstate South Carolina
- Romantic Hotels in Upstate South Carolina
- Shopping Hotels in Upstate South Carolina
- Sports Hotels in Upstate South Carolina
- Wedding Hotels in Upstate South Carolina
































