Search Hotels Near Wilkes Regional, Winston-Salem

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19 Dec - 20 Dec
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Our top choices for Wilkes Regional hotels

Free continental breakfast
Hampton Inn Winston-Salem Hanes Mall

Hampton Inn Winston-Salem Hanes Mall

Hampton Inn Winston-Salem Hanes Mall
2.5 star property
1 km from Wilkes Regional
9.2 out of 10, Wonderful, (1000)
"Super friendly staff, very clean and good breakfast "
United States
jane
The price is 2.784.553 ₫
3.146.544 ₫ total
includes taxes & fees
26 Dec - 27 Dec
Hampton Inn Winston-Salem Hanes Mall
Standard Room, 1 King Bed with Sofa bed, Non Smoking | Pillow-top beds, desk, laptop workspace, blackout curtains
Comfort Suites Hanes Mall

Comfort Suites Hanes Mall

Comfort Suites Hanes Mall
2.5 star property
0.7 km from Wilkes Regional
8.8 out of 10, Excellent, (1003)
"Spacious room, with good breakfast options."
United States
Rachel
The price is 2.438.919 ₫
2.815.472 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Comfort Suites Hanes Mall
Outdoor pool
Fairfield Inn & Suites by Marriott Winston-Salem Hanes Mall

Fairfield Inn & Suites by Marriott Winston-Salem Hanes Mall

Fairfield Inn & Suites by Marriott Winston-Salem Hanes Mall
2.5 star property
1.3 km from Wilkes Regional
9.0 out of 10, Wonderful, (666)
"The room was perfect and clean and the staff was very welcoming and friendly!"
United States
Kelley
The price is 2.764.020 ₫
3.123.343 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Fairfield Inn & Suites by Marriott Winston-Salem Hanes Mall
Restaurant
Home2 Suites by Hilton Winston-Salem Hanes Mall

Home2 Suites by Hilton Winston-Salem Hanes Mall

Home2 Suites by Hilton Winston-Salem Hanes Mall
3.0 star property
1.8 km from Wilkes Regional
9.2 out of 10, Wonderful, (481)
"Nearby Mall and restaurants"
United States
Pablo
The price is 2.784.553 ₫
3.146.544 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Home2 Suites by Hilton Winston-Salem Hanes Mall
Lobby
Springhill Suites by Marriott Winston-Salem Hanes Mall

Springhill Suites by Marriott Winston-Salem Hanes Mall

Springhill Suites by Marriott Winston-Salem Hanes Mall
3.0 star property
2 km from Wilkes Regional
9.0 out of 10, Wonderful, (1000)
"Nice clean quiet stay! "
United States
Tara
The price is 2.662.673 ₫
3.008.820 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Springhill Suites by Marriott Winston-Salem Hanes Mall
Lobby
Hilton Garden Inn Winston-Salem/Hanes Mall

Hilton Garden Inn Winston-Salem/Hanes Mall

Hilton Garden Inn Winston-Salem/Hanes Mall
3.0 star property
2.4 km from Wilkes Regional
8.8 out of 10, Excellent, (719)
"The room was very comfortable ,the staff was friendly and helpful great stay Thank You Jay "
United States
Jay
The price is 3.124.132 ₫
3.530.269 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Hilton Garden Inn Winston-Salem/Hanes Mall
Exterior
La Quinta Inn & Suites by Wyndham Winston-Salem

La Quinta Inn & Suites by Wyndham Winston-Salem

La Quinta Inn & Suites by Wyndham Winston-Salem
3.0 star property
0.7 km from Wilkes Regional
8.2 out of 10, Very good, (11)
"Best La Quinta we have stayed at in a few years. Room was great as was the location near other amenities."
United States
Melvin
The price is 1.942.711 ₫
2.195.263 ₫ total
includes taxes & fees
22 Dec - 23 Dec
La Quinta Inn & Suites by Wyndham Winston-Salem
Property amenity
Courtyard by Marriott Winston-Salem Hanes Mall

Courtyard by Marriott Winston-Salem Hanes Mall

Courtyard by Marriott Winston-Salem Hanes Mall
3.0 star property
1.3 km from Wilkes Regional
8.4 out of 10, Very good, (708)
"Clean Room, nice staff Would definitely stay here again "
United States
Dan
The price is 2.579.752 ₫
2.915.120 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Courtyard by Marriott Winston-Salem Hanes Mall
View from property
Residence Inn by Marriott Winston-Salem Hanes Mall

Residence Inn by Marriott Winston-Salem Hanes Mall

Residence Inn by Marriott Winston-Salem Hanes Mall
3.0 star property
2.4 km from Wilkes Regional
8.8 out of 10, Excellent, (388)
"Great customer service, the rooms need to be upgraded and the breakfast was really bad and had no flavor . Good location for shopping and eating out "
United States
Estephanie
The price is 2.819.300 ₫
3.185.809 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
Residence Inn by Marriott Winston-Salem Hanes Mall
Interior
Sleep Inn Hanes Mall

Sleep Inn Hanes Mall

Sleep Inn Hanes Mall
2.5 star property
Williamsburg Square, 0.9 km from Wilkes Regional
7.8 out of 10, Good, (1003)
"Great stay! "
United States
Raphel
The price is 1.855.052 ₫
2.155.701 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Sleep Inn Hanes Mall
Exterior
Best Western Plus Hanes Mall Hotel

Best Western Plus Hanes Mall Hotel

Best Western Plus Hanes Mall Hotel
2.5 star property
2 km from Wilkes Regional
7.6 out of 10, Good, (1000)
"Clean and good breakfast friendly staff"
United States
Raymond
The price is 2.083.808 ₫
2.354.703 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Best Western Plus Hanes Mall Hotel
Queen Suite Two Queen Beds Accessible | Pillow-top beds, individually decorated, individually furnished, desk
WoodSpring Suites Winston-Salem near Hanes Mall

WoodSpring Suites Winston-Salem near Hanes Mall

WoodSpring Suites Winston-Salem near Hanes Mall
2.5 star property
2 km from Wilkes Regional
7.8 out of 10, Good, (265)
"The hotel is convenient but lacks any professional appeal. Seems like a party place. "
United States
Charles
The price is 1.947.976 ₫
2.201.213 ₫ total
includes taxes & fees
21 Dec - 22 Dec
WoodSpring Suites Winston-Salem near Hanes Mall
Lobby
Suburban Studios Winston-Salem near Hanes Mall

Suburban Studios Winston-Salem near Hanes Mall

Suburban Studios Winston-Salem near Hanes Mall
2.0 star property
Williamsburg Square, 0.8 km from Wilkes Regional
7.0 out of 10, Good, (261)
"clean room, staff, allowed me to check is early."
United States
Gary
The price is 1.342.524 ₫
1.517.052 ₫ total
includes taxes & fees
18 Jan - 19 Jan 2026
Suburban Studios Winston-Salem near Hanes Mall
Seasonal outdoor pool
Quality Inn & Suites Hanes Mall

Quality Inn & Suites Hanes Mall

Quality Inn & Suites Hanes Mall
2.5 star property
2.4 km from Wilkes Regional
6.8 out of 10, (1001)
"Yes, the hotel met my expectations and staffs very nice."
United States
Isaul
The price is 1.463.614 ₫
1.653.885 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Quality Inn & Suites Hanes Mall
Lobby
Red Roof Inn Winston-Salem

Red Roof Inn Winston-Salem

Red Roof Inn Winston-Salem
2.0 star property
0.7 km from Wilkes Regional
5.4 out of 10, (425)
"Clean rooms "
United States
Shirley
The price is 1.811.091 ₫
2.046.532 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Red Roof Inn Winston-Salem
Lobby
Summit Street Inns

Summit Street Inns

Summit Street Inns
3.5 star property
6.2 km from Wilkes Regional
9.8 out of 10, Exceptional, (226)
"Great Hotel! Favorite place to stay in Winston Salem."
United States
Pedro
The price is 3.510.305 ₫
3.966.644 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Summit Street Inns
Premium bedding, desk, blackout curtains, iron/ironing board
The Historic Brookstown Inn, Trademark Collection by Wyndham

The Historic Brookstown Inn, Trademark Collection by Wyndham

The Historic Brookstown Inn, Trademark Collection by Wyndham
3.5 star property
6.4 km from Wilkes Regional
9.6 out of 10, Exceptional, (1002)
"Great place and people. Good vibe and excellent service "
United States
Yash
The price is 2.961.450 ₫
3.346.438 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
The Historic Brookstown Inn, Trademark Collection by Wyndham
Property entrance
Holiday Inn Exp Winston Salem by IHG

Holiday Inn Exp Winston Salem by IHG

Holiday Inn Exp Winston Salem by IHG
3.0 star property
4.1 km from Wilkes Regional
8.4 out of 10, Very good, (850)
"We were there for one night and everything went great, will stay with them again. "
United States
Clyde
The price is 2.184.892 ₫
2.468.928 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Holiday Inn Exp Winston Salem by IHG
Free buffet breakfast
Holiday Inn Express Winston-Salem Medical Center Area by IHG

Holiday Inn Express Winston-Salem Medical Center Area by IHG

Holiday Inn Express Winston-Salem Medical Center Area by IHG
2.5 star property
4.8 km from Wilkes Regional
8.4 out of 10, Very good, (1003)
"Excellent staff, clean and comfortable rooms. Will return!"
United States
David
The price is 2.342.836 ₫
2.647.405 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Holiday Inn Express Winston-Salem Medical Center Area by IHG
Exterior
Hampton Inn & Suites Winston-Salem Downtown

Hampton Inn & Suites Winston-Salem Downtown

Hampton Inn & Suites Winston-Salem Downtown
2.5 star property
6.8 km from Wilkes Regional
9.0 out of 10, Wonderful, (642)
"Clean room, great staff"
United States
Loretta
The price is 2.135.403 ₫
2.413.007 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn & Suites Winston-Salem Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Wilkes Regional Hotel Reviews

Hotels near other Wilkes Regional attractions

Hanes Mall

4.2/5 (656 reviews)
You can search for that perfect souvenir at Hanes Mall during your visit to Winston-Salem. Attend a sporting event or simply enjoy the local cheese shops while you're in the area.
See properties

Adventure Landing Winston-Salem

Enjoy an outing to Adventure Landing Winston-Salem during your stay in Winston-Salem. Attend a sporting event or visit the shops in this family-friendly area.
See properties

Frequently asked questions

What's the area like around Wilkes Regional?
Wilkes Regional is located in Winston-Salem. This family-friendly area is known for its array of dining options and sporting events. If you're looking for a convenient place to stay, take a look at the 19 hotels and other accommodation options you'll find within a mile.
How many hotels will I find close to Wilkes Regional?
Expedia has 19 hotels and other accommodation options within a mile from Wilkes Regional.
If I need to cancel the hotel reservation for my stay near Wilkes Regional, will I receive a refund?
Yes, most hotel bookings are refundable if you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to get the top deals on offer near Wilkes Regional.
What can I see and do near Wilkes Regional?
Study the collections at Old Salem, Reynolda House Museum of American Art or Southeastern Center for Contemporary Art. You might spend a leisurely day outdoors at Reynolda Gardens and Hobby Park. Attractions like Theatre Alliance and Frank L. Horton Museum Center highlight the local culture.