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17 Dec - 18 Dec
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18 Dec - 19 Dec
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19 Dec - 21 Dec
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26 Dec - 28 Dec

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Our top choices for Zona Ospedaliera hotels

Deluxe Double or Twin Room (#3) | Minibar, desk, blackout curtains, soundproofing
F Rooms

F Rooms

F Rooms
Zona Ospedaliera
7.8 out of 10, Good, (8)
"Nobody to open the door."
Canada
Mihai
F Rooms
Property grounds
HOTEL FEDERICO II

HOTEL FEDERICO II

HOTEL FEDERICO II
3.0 star property
Zona Ospedaliera
7.4 out of 10, Good, (156)
"The place is quite with friendly staff"
Canada
lina
HOTEL FEDERICO II
Property entrance
Hotel Palazzo Argenta

Hotel Palazzo Argenta

Hotel Palazzo Argenta
3.0 star property
4.7 km from Zona Ospedaliera
8.8 out of 10, Excellent, (335)
"Room was very clean, courteous and knowledgeable staff that were very helpful. If I go back to Naples I will definitely stay there again."
United States
Tony P
The price is 1.580.946 ₫
2.017.377 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Hotel Palazzo Argenta
Exterior
Holiday Inn Naples by IHG

Holiday Inn Naples by IHG

Holiday Inn Naples by IHG
4.0 star property
6.2 km from Zona Ospedaliera
8.2 out of 10, Very good, (1008)
"Room was spotless and stocked with everything you need. Staff was welcoming and quick to respond to any needs. Very quiet and great location for quick run to the airport."
United States
Layna
The price is 1.771.227 ₫
2.597.799 ₫ total
includes taxes & fees
20 Dec - 21 Dec
Holiday Inn Naples by IHG
Reception
CX Naples Centrale

CX Naples Centrale

CX Naples Centrale
Naples City Centre, 5.6 km from Zona Ospedaliera
9.6 out of 10, Exceptional, (17)
"Great place for a family with children "
United States
Jared
The price is 2.152.365 ₫
2.646.124 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
CX Naples Centrale
Indoor pool, outdoor pool, free pool cabanas, pool umbrellas
Hotel Mary

Hotel Mary

Hotel Mary
4.0 star property
29.3 km from Zona Ospedaliera
9.2 out of 10, Wonderful, (864)
"breakfast was great! "
United States
Lucy
Hotel Mary
Premium bedding, down duvets, minibar, in-room safe
Hotel Herculaneum

Hotel Herculaneum

Hotel Herculaneum
3.0 star property
13.5 km from Zona Ospedaliera
8.6 out of 10, Excellent, (685)
"Great place to stay"
United Kingdom
Luiz Antonio
The price is 1.434.694 ₫
1.701.868 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
Hotel Herculaneum
Standard Apartment | Living area | 40-inch Smart TV with digital channels, TV
La Piazzetta Guest House

La Piazzetta Guest House

La Piazzetta Guest House
30.2 km from Zona Ospedaliera
9.6 out of 10, Exceptional, (542)
"The staff was fantastic and we had a great stay. "
United States
Izabela
The price is 2.277.292 ₫
2.505.021 ₫ total
includes taxes & fees
19 Dec - 20 Dec
La Piazzetta Guest House
Hypo-allergenic bedding, down duvets, in-room safe, desk
B&B Hotel Napoli

B&B Hotel Napoli

B&B Hotel Napoli
3.0 star property
Naples City Centre, 5 km from Zona Ospedaliera
8.4 out of 10, Very good, (1001)
"Great location. "
Canada
Edna
The price is 1.842.076 ₫
2.304.619 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
B&B Hotel Napoli
Daily buffet breakfast (EUR 14 per person)
Starhotels Terminus

Starhotels Terminus

Starhotels Terminus
4.0 star property
Naples City Centre, 5.3 km from Zona Ospedaliera
9.0 out of 10, Wonderful, (1005)
"This was a great hotel! Would stay there again."
United States
Jeanine
The price is 3.626.798 ₫
4.329.665 ₫ total
includes taxes & fees
16 Jan - 17 Jan 2026
Starhotels Terminus
Indoor spa tub
Tasso Suites & Spa

Tasso Suites & Spa

Tasso Suites & Spa
3.0 star property
30.3 km from Zona Ospedaliera
9.2 out of 10, Wonderful, (520)
"Great spot close to the beach and all the restaurants and shopping in Tasso Square."
United States
Jennifer
The price is 1.877.163 ₫
2.064.879 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Tasso Suites & Spa
Suite con Jacuzzi e Vista Mare | Frette Italian sheets, premium bedding, down duvets, minibar
Hotel & Resort Tre Fontane Luxury

Hotel & Resort Tre Fontane Luxury

Hotel & Resort Tre Fontane Luxury
10.9 km from Zona Ospedaliera
9.2 out of 10, Wonderful, (385)
"This is the place to stay!!!!! Everything was perfect! The staff went above and beyond! The views were amazing, the food was amazing, and it truly was the perfect place! "
United States
Michelle
The price is 2.833.963 ₫
3.117.359 ₫ total
includes taxes & fees
27 Dec - 28 Dec
Hotel & Resort Tre Fontane Luxury
Seasonal outdoor pool, open 9:00 AM to 7:00 PM, pool umbrellas
Towers Hotel Stabiae Sorrento Coast

Towers Hotel Stabiae Sorrento Coast

Towers Hotel Stabiae Sorrento Coast
4.0 star property
28.4 km from Zona Ospedaliera
8.6 out of 10, Excellent, (593)
"This hotel is beautiful and has amazing views and amenities, however, you will need a taxi or a car to get around as it’s very secluded from everything. "
United States
Geraldine
The price is 2.147.283 ₫
2.485.799 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Towers Hotel Stabiae Sorrento Coast
Executive Room | Terrace/patio
Gold Tower Lifestyle Hotel

Gold Tower Lifestyle Hotel

Gold Tower Lifestyle Hotel
4.0 star property
7 km from Zona Ospedaliera
9.2 out of 10, Wonderful, (553)
"This hotel was amazing, the view was breathtaking, although the weather wasn't too good with light showers, my family and I enjoyed our stay. "
United States
Aurore Murielle
The price is 2.631.537 ₫
3.234.879 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Gold Tower Lifestyle Hotel
Beach views
Hotel Puntaquattroventi

Hotel Puntaquattroventi

Hotel Puntaquattroventi
14.6 km from Zona Ospedaliera
9.0 out of 10, Wonderful, (301)
"Staff was incredible- LOVED our stay"
United States
Patricia
The price is 2.530.325 ₫
2.907.063 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Hotel Puntaquattroventi
Exterior
Resort & Winery Bosco De Medici

Resort & Winery Bosco De Medici

Resort & Winery Bosco De Medici
4.0 star property
27.1 km from Zona Ospedaliera
9.4 out of 10, Exceptional, (633)
"Very beautiful and comforting place with very kind caring staffs."
United States
Jungho
The price is 3.039.099 ₫
3.590.418 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Resort & Winery Bosco De Medici
Exterior
The Five Rooms Napoli

The Five Rooms Napoli

The Five Rooms Napoli
Naples City Centre, 5.1 km from Zona Ospedaliera
9.6 out of 10, Exceptional, (556)
"Staff was courteous and very helpful with local knowledge, room was "
Canada
Desiree Barbara Nicole
The price is 2.909.873 ₫
3.479.197 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
The Five Rooms Napoli
Exterior
Hotel Zeus Pompei

Hotel Zeus Pompei

Hotel Zeus Pompei
3.0 star property
26.3 km from Zona Ospedaliera
8.4 out of 10, Very good, (265)
"Staff was courteous, room was clean, good location, and good value for money"
Canada
Marian
The price is 1.900.287 ₫
2.275.998 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Hotel Zeus Pompei
Couples treatment room(s), sauna, hot tub, steam room
La Medusa Dimora di Charme

La Medusa Dimora di Charme

La Medusa Dimora di Charme
4.0 star property
30.6 km from Zona Ospedaliera
9.6 out of 10, Exceptional, (578)
"The property was beautiful. Wonderful lobby and excellent room. Wonderful views of Vesuvius. The grounds have numerous orange trees and we got fresh squeezed orange juice for breakfast. We did not utilize the pool or spa and spent our days seeing the ruins of Herculaneum, Oplontis, Villa San Marco, and Villa San Ariana. Wee hadd seen Pompeii before. We also travelled to Naples and saw the docks, saw the Duomo, and saw the amazing MANN (MUSEO ARCHEALOGICA NATIONALE NAPLES`0."
United States
Charles
The price is 3.196.716 ₫
3.640.176 ₫ total
includes taxes & fees
18 Dec - 19 Dec
La Medusa Dimora di Charme
Reception
Hotel Nice

Hotel Nice

Hotel Nice
3.0 star property
30.5 km from Zona Ospedaliera
8.4 out of 10, Very good, (301)
"Brilliant location, clean and tidy, helpful staff "
United Kingdom
Michael
The price is 2.361.636 ₫
2.597.799 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Hotel Nice
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Zona Ospedaliera

Find the best Zona Ospedaliera areas for the activities you enjoy most.
San Lorenzo Maggiore showing a city and a house

Naples City Centre

Known for its abundant dining options and interesting museums, there's plenty to explore in Naples City Centre. Top attractions like Port of Naples and Mercato di Porta Nolana are major draws, and you can catch the metro at Garibaldi Tram Stop or EAV - Capolinea Porta Nolana Tram Stop to see more of the city.

Historical Center

Port of Naples and Via Toledo are top sights in Historical Center, and you should be sure to explore the popular shops. Hop aboard the metro at Toledo Station or Municipio Station to see more sights in the area.

Chiaia

Travellers choose Chiaia for its ample dining options. Hop aboard the metro at Arco Mirelli - Repubblica Station or Piazza Amedeo Station and check out top sights like Naples Aquarium.

Pendino

If you're spending time in Pendino, check out sights like Corso Umberto I or Calata di Massa Port and hop on the metro to see more of the city at Duomo Station or Via Marina - Duomo Tram Stop.

San Lorenzo Maggiore featuring interior views

Decumani

While you're in Decumani, take in top sights like Via San Gregorio Armeno and jump on the metro at Dante Station to see more of the city.

Top Zona Ospedaliera Hotel Reviews

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Frequently asked questions

What's it like in Zona Ospedaliera?
Zona Ospedaliera is a neighbourhood that travellers like for its restaurants.
How many hotels should I expect to find in the Zona Ospedaliera area?
Book one of Expedia's 6 hotels and other accommodation options in Zona Ospedaliera and start exploring everything Naples has to offer.
If I need to cancel my hotel reservation in Zona Ospedaliera, will I receive a refund?
Yes! Most hotel room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best deals in Zona Ospedaliera.
What is there to do around this Naples neighbourhood?
Teatro Il Primo, Parco Urbano dei Camaldoli and Sacra Ruota degli Esposti are just a few of the places to visit in and around Zona Ospedaliera. While you're out sightseeing, Basilica SS Annunziata and Il Carosello dei Piccoli are a couple of additional sights to visit in Naples.
How can I get around Zona Ospedaliera and the greater Naples area?
Ready to get out and explore the city? Policlinico Station is the closest metro station.