
Find hotels in Charleston, MO from 1.661.503 ₫
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Charleston
Family friendly
Pet friendly
Check prices for these dates
Our top choices for Charleston hotels

Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MOCharleston
6.8 out of 10, (620 reviews)
The price is 1.631.429 ₫
1.810.478 ₫ total
includes taxes & fees
17 Jan - 18 Jan

Eagle Inn Charleston
Eagle Inn CharlestonCharleston
6.6 out of 10, (105 reviews)
The price is 1.589.133 ₫
1.763.572 ₫ total
includes taxes & fees
17 Jan - 18 Jan

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,006 reviews)
The price is 2.364.127 ₫
2.666.769 ₫ total
includes taxes & fees
21 Jan - 22 Jan

Best Western Plus Sikeston
Best Western Plus SikestonSikeston
8.4 out of 10, Very good, (1,002 reviews)
The price is 1.875.487 ₫
2.137.587 ₫ total
includes taxes & fees
25 Jan - 26 Jan

Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.4 out of 10, Exceptional, (1,002 reviews)
The price is 2.469.211 ₫
2.838.844 ₫ total
includes taxes & fees
21 Jan - 22 Jan

Quality Inn Cairo I-57
Quality Inn Cairo I-57Cairo
6.6 out of 10, (275 reviews)
The price is 1.869.182 ₫
2.074.419 ₫ total
includes taxes & fees
24 Jan - 25 Jan

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)Sikeston
8.4 out of 10, Very good, (730 reviews)
The price is 1.457.778 ₫
1.661.503 ₫ total
includes taxes & fees
18 Jan - 19 Jan

The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (490 reviews)
The price is 2.529.897 ₫
2.854.078 ₫ total
includes taxes & fees
20 Jan - 21 Jan

Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
9.0 out of 10, Wonderful, (1,000 reviews)
The price is 1.838.707 ₫
2.092.748 ₫ total
includes taxes & fees
21 Jan - 22 Jan

Hampton Inn Sikeston
Hampton Inn SikestonSikeston
9.0 out of 10, Wonderful, (463 reviews)
The price is 2.674.210 ₫
3.027.874 ₫ total
includes taxes & fees
1 Feb - 2 Feb

Pear Tree Inn Sikeston
Pear Tree Inn SikestonSikeston
9.4 out of 10, Exceptional, (1,003 reviews)
The price is 1.970.062 ₫
2.264.823 ₫ total
includes taxes & fees
21 Jan - 22 Jan

Quiet Country Stay: Modern Home Near Paducah
Quiet Country Stay: Modern Home Near PaducahCunningham
The price is 3.178.791 ₫
7.617.802 ₫ total
includes taxes & fees
25 Jan - 26 Jan

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1,000 reviews)
The price is 2.391.207 ₫
2.697.615 ₫ total
includes taxes & fees
25 Jan - 26 Jan

Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.2 out of 10, Wonderful, (49 reviews)
The price is 2.653.371 ₫
3.004.279 ₫ total
includes taxes & fees
29 Jan - 30 Jan

Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
9.6 out of 10, Exceptional, (479 reviews)
The price is 3.283.875 ₫
3.721.090 ₫ total
includes taxes & fees
15 Feb - 16 Feb

Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (1,001 reviews)
The price is 2.364.127 ₫
2.666.769 ₫ total
includes taxes & fees
21 Jan - 22 Jan

Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham SikestonSikeston
7.2 out of 10, Good, (1,001 reviews)
The price is 1.652.446 ₫
1.883.376 ₫ total
includes taxes & fees
18 Jan - 19 Jan

Comfort Inn & Suites Sikeston I-55
Comfort Inn & Suites Sikeston I-55Sikeston
8.4 out of 10, Very good, (284 reviews)
The price is 2.210.705 ₫
2.519.651 ₫ total
includes taxes & fees
21 Jan - 22 Jan

Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical CenterCape Girardeau
9.0 out of 10, Wonderful, (1,001 reviews)
The price is 2.994.631 ₫
3.378.450 ₫ total
includes taxes & fees
18 Jan - 19 Jan
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Learn more about Charleston
Quaint Charleston is calling! Discover its opera, entertainment, dining and more.

Top Charleston Hotel Reviews

Drury Inn & Suites Sikeston, MO
10/10 Excellent

Pear Tree Inn Cape Girardeau Near the Medical Center
10/10 Excellent
More cheap stays in Charleston

Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
The price is 1.652.446 ₫ per night from 18 Jan to 19 Jan
1.652.446 ₫
1.883.376 ₫ total
18 Jan - 19 Jan
includes taxes & fees
7.2/10 Good! (1,002 reviews)
Hotels in Charleston with star rating

4 Star Hotels
1 properties




































































