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Florence County
South Carolina
Hotels
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Holiday Rentals in Florence County Florence County Car Hire Florence County Holidays

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Florence County Accommodation: Most Popular Cities to Stay

A historic brick building with arched windows and a river in the foreground.

A sunset over a forested landscape with a river and a parking lot.

A person walking on a rope bridge surrounded by dense forest.

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26 Sep - 27 Sep

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Our top choices for Florence County hotels

A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.

A hotel room with a large bed, a desk with a lamp, a chair, a TV, and a window with curtains.

A modern kitchen with a patterned backsplash, wooden cabinets, and stainless steel appliances.

A modern living room with a grey sofa, a flat-screen TV, geometric wall art, and a bookshelf with decorative items.

1. Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 star property

Florence

9.0 out of 10, Wonderful, (2,454 reviews)

9.0/10

Wonderful

(2,454 reviews)

"Great location, friendly staff."

"Great location, friendly staff."

United States

Windia

The price is 2.319.478 ₫

2.319.478 ₫

2.597.817 ₫ total

includes taxes & fees

18 Oct - 19 Oct

Park Inn by Radisson Florence, SC

A hotel room with a desk, chair, bed, and a yellow sofa.

A hotel dining area with wooden tables and chairs, a fireplace, and a television.

A swimming pool with lounge chairs and a building with balconies.

A reception desk with a stone wall backdrop, a sign reading 'Quality Choice Hotels,' and a reception area with a wooden reception desk and two chairs.

2. Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 star property

Florence

8.4 out of 10, Very good, (378 reviews)

8.4/10

Very good

(378 reviews)

"-clean rooms, dog friendly and comfy bed."

"-clean rooms, dog friendly and comfy bed."

Canada

Noémie

The price is 2.477.920 ₫

2.477.920 ₫

2.775.271 ₫ total

includes taxes & fees

3 Oct - 4 Oct

Quality Inn & Suites Florence Civic Center

A spacious lobby with a checkered floor, a reception desk, and a chandelier.

A two-story building with a brick facade, a flat roof, and a covered entrance area.

A spacious dining area with multiple tables and chairs, large windows offering a view of the parking lot, and a television mounted on the wall.

A vending area with snack and drink options, including Pepsi refrigerators and a 'MARKET' display with various products.

3. Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2.0 star property

Florence

8.6 out of 10, Excellent, (2,732 reviews)

8.6/10

Excellent

(2,732 reviews)

"Very nice place to stay"

"Very nice place to stay"

United States

HOMERO

The price is 1.677.920 ₫

1.677.920 ₫

1.879.272 ₫ total

includes taxes & fees

29 Sept - 30 Sept

Howard Johnson by Wyndham Florence

A modern lobby with a stone column, a fireplace, and yellow rocking chairs around a central table.

A modern cafeteria with long wooden tables, green chairs, and yellow accents.

An outdoor patio with a wooden table and wicker chairs, a barbecue grill, and a swimming pool in the background.

A hotel with a modern design, featuring a prominent sign for the 'Country Inn & Suites by Radisson.'

4. Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

2.5 star property

Florence

8.2 out of 10, Very good, (303 reviews)

8.2/10

Very good

(303 reviews)

"The staff was great and the room was clean! Great pit stop on our way to Disney!"

"The staff was great and the room was clean! Great pit stop on our way to Disney!"

United States

Tienia

The price is 2.108.569 ₫

2.108.569 ₫

2.464.195 ₫ total

includes taxes & fees

25 Oct - 26 Oct

Spark by Hilton Florence North I-95, SC

A hotel lobby with a reception desk, seating area, and a television screen.

A Comfort Inn & Suites hotel with a covered entrance, brick facade, and multiple windows.

A hotel room with a sectional sofa, two ottomans, a bed with a green bedspread, and framed pictures on the wall.

A spacious dining area with multiple tables and chairs, large windows, and a flat-screen TV mounted on the wall.

5. Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 star property

Florence

9.0 out of 10, Wonderful, (1,367 reviews)

9.0/10

Wonderful

(1,367 reviews)

"Breakfast was excellent. Room was clean and quiet."

"Breakfast was excellent. Room was clean and quiet."

United States

Mila

The price is 2.627.270 ₫

2.627.270 ₫

2.942.543 ₫ total

includes taxes & fees

18 Oct - 19 Oct

Comfort Inn & Suites Florence Center Area

An outdoor patio area with tables and chairs, a brick wall, and a glass door leading to the interior.

A spacious lobby with a grand staircase, plush seating, and a modern kitchen area.

A spacious bar area with a wooden floor, multiple bar stools, and a variety of bottles on shelves.

A spacious living room with hardwood flooring, a staircase, and a large window.

6. The Inn at the Crossroads

The Inn at the Crossroads

2.0 star property

Lake City

9.4 out of 10, Exceptional, (982 reviews)

9.4/10

Exceptional

(982 reviews)

"Great stay!!"

"Great stay!!"

United States

Paige

The price is 2.575.907 ₫

2.575.907 ₫

2.885.015 ₫ total

includes taxes & fees

27 Oct - 28 Oct

The Inn at the Crossroads

A hotel room with two beds, a wooden headboard, a nightstand, and three sunset paintings on the wall.

A Days Inn hotel with a modern design, featuring a parking lot and well-maintained landscaping.

A modern hotel room with a large bed, two armchairs, a desk with a computer, and a decorative wall.

A modern kitchen with a central island, a dining area with chairs, a large window with a view of palm trees, and a flat-screen TV mounted on the wall.

7. Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 star property

Florence

7.2 out of 10, Good, (1,004 reviews)

7.2/10

Good

(1,004 reviews)

"Clean and easy access to restaurants"

"Clean and easy access to restaurants"

United States

Jefferson

The price is 1.792.206 ₫

1.792.206 ₫

2.007.271 ₫ total

includes taxes & fees

27 Sept - 28 Sept

Days Inn by Wyndham Florence Near Civic Center

A hotel room with two beds, a wooden headboard, a window with curtains, and a wall-mounted air conditioner.

A spacious lobby with a reception desk, a large window display, and a 'market' sign on the wall.

A modern kitchen with a built-in coffee station, a refrigerator, and a seating area with a patterned rug.

8. SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence

3.0 star property

Florence

8.2 out of 10, Very good, (1,006 reviews)

8.2/10

Very good

(1,006 reviews)

"The room Was clean and comfortable and the breakfast was good."

"The room Was clean and comfortable and the breakfast was good."

United States

John

The price is 2.518.625 ₫

2.518.625 ₫

2.975.513 ₫ total

includes taxes & fees

18 Oct - 19 Oct

SpringHill Suites by Marriott Florence

A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.

A modern bar area with a long counter, bar stools, and a variety of bottles and glasses.

A modern lounge area with brick walls, large windows, and contemporary furniture.

A multi-story hotel with a modern facade, featuring a prominent 'Hyatt Place' sign on the right.

9. Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3.0 star property

Florence

9.0 out of 10, Wonderful, (1,000 reviews)

9.0/10

Wonderful

(1,000 reviews)

"Convenient hotel, clean and near restaurant options."

"Convenient hotel, clean and near restaurant options."

United States

Ivette

The price is 2.857.140 ₫

2.857.140 ₫

3.199.997 ₫ total

includes taxes & fees

8 Oct - 9 Oct

Hyatt Place Florence Downtown

A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.

A Hampton Inn & Suites with a large sign, brick facade, and a parking lot.

A hotel lobby with a reception desk, seating area, and a welcome mat.

A hotel room with two beds, a desk, a TV, and a window with patterned curtains.

10. Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center

2.5 star property

Florence

9.0 out of 10, Wonderful, (971 reviews)

9.0/10

Wonderful

(971 reviews)

"The room was clean, and staff were very helpful and friendly. The breakfast was good. Will stay again."

"The room was clean, and staff were very helpful and friendly. The breakfast was good. Will stay again."

United States

Bill

The price is 2.854.023 ₫

2.854.023 ₫

3.196.506 ₫ total

includes taxes & fees

25 Oct - 26 Oct

Hampton Inn & Suites Florence Center

A hotel room with a large bed, a desk with a chair, a television, and a walk-in closet.

A conference room with a long table, chairs, a coffee station, and a clock on the wall.

A modern office space with two desks, chairs, a printer, and a colorful abstract painting on the wall.

A coffee station with two coffee machines and a display of coffee pods and cups.

11. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

2.5 star property

Florence

9.2 out of 10, Wonderful, (1,000 reviews)

9.2/10

Wonderful

(1,000 reviews)

"Wonderful hotel and in a great location!"

"Wonderful hotel and in a great location!"

United States

Leigh

The price is 3.272.724 ₫

3.272.724 ₫

3.665.449 ₫ total

includes taxes & fees

26 Oct - 27 Oct

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

A modern kitchen with dark wooden cabinets, a stainless steel refrigerator, a microwave, and a coffee maker. There is a dining area with two red chairs and a table.

A conference room with round tables, chairs, and a carpeted floor.

A hotel room with a bed, a desk, a TV, a refrigerator, and a painting on the wall.

A hotel room with a sofa, a dining table, a coffee maker, a TV, and artwork on the wall.

12. Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG

3.0 star property

Florence

9.4 out of 10, Exceptional, (1,002 reviews)

9.4/10

Exceptional

(1,002 reviews)

"Enjoyed our stay."

"Enjoyed our stay."

United States

Tishia

The price is 3.716.856 ₫

3.716.856 ₫

4.162.880 ₫ total

includes taxes & fees

11 Oct - 12 Oct

Staybridge Suites Florence - Civic Center by IHG

A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.

A self-service beverage station with refrigerated and non-refrigerated drink options, snack shelves, and a sign indicating the location.

A modern kitchen with a coffee station, a dining area with a table and chairs, and a living area with a sofa and a coffee table.

A reception area with a wooden desk, a map on the wall, and a sign welcoming visitors to Florence, SC.

13. TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence

3.0 star property

Florence

9.0 out of 10, Wonderful, (905 reviews)

9.0/10

Wonderful

(905 reviews)

"Always a good stay"

"Always a good stay"

United Kingdom

William

The price is 3.068.828 ₫

3.068.828 ₫

3.437.089 ₫ total

includes taxes & fees

27 Sept - 28 Sept

TownePlace Suites by Marriott Florence

A swimming pool with lounge chairs and a building with a sign reading "BAYMONT".

A modern living room with a sectional sofa, a coffee table, and a flat-screen TV mounted on the wall.

A bathroom with a sink, mirror, towel rack, and a towel hanging on the wall.

A hotel room with a large bed, a desk, a chair, a TV, and a painting of a waterfall on the wall.

14. Super 8 by Wyndham Florence

Super 8 by Wyndham Florence

2.0 star property

Florence

7.2 out of 10, Good, (1,005 reviews)

7.2/10

Good

(1,005 reviews)

"Clean room, nice staff."

"Clean room, nice staff."

United States

Agnes

The price is 1.346.752 ₫

1.346.752 ₫

1.508.570 ₫ total

includes taxes & fees

27 Sept - 28 Sept

Super 8 by Wyndham Florence

A hotel room with a bed, bedside table with a phone, a desk with a chair, a TV mounted on the wall, and a window with curtains.

A reception area with a wooden counter, a seating area with tables and chairs, and a large window with a view.

A conference room with a wooden table, chairs, a TV, and a computer on a shelf.

A multi-story hotel with a prominent entrance marked '1912'.

15. Microtel Inn & Suites by Wyndham Florence

Microtel Inn & Suites by Wyndham Florence

2.0 star property

Florence

7.0 out of 10, Good, (1,002 reviews)

7.0/10

Good

(1,002 reviews)

"I enjoyed my stays"

"I enjoyed my stays"

United States

Carletta

The price is 1.532.466 ₫

1.532.466 ₫

1.716.362 ₫ total

includes taxes & fees

29 Sept - 30 Sept

Microtel Inn & Suites by Wyndham Florence

A modern lobby with seating areas, a reception desk, and a large wall with a decorative panel.

A modern coffee station with a counter, coffee machines, and a seating area with chairs.

A hotel room with a bed, a blue sofa, a brown ottoman, a black office chair, a desk, a lamp, and three framed pictures on the wall.

A Comfort Suites hotel with a modern design, featuring a prominent entrance with columns, a covered walkway, and a clear blue sky.

16. Comfort Suites Florence I-95

Comfort Suites Florence I-95

2.5 star property

Florence

8.2 out of 10, Very good, (1,001 reviews)

8.2/10

Very good

(1,001 reviews)

"Very convenient to highway"

"Very convenient to highway"

United States

Denise

The price is 2.269.291 ₫

2.269.291 ₫

2.645.503 ₫ total

includes taxes & fees

25 Oct - 26 Oct

Comfort Suites Florence I-95

A spacious lobby with a high ceiling, a central seating area, and a staircase leading to an upper level.

A hotel room with a bed, a sofa, a desk, and a TV.

A modern breakfast area with a buffet setup, including a microwave, coffee maker, and various food items.

A hotel room with a bed, sofa, TV, and a desk.

17. La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

3.0 star property

Florence

7.8 out of 10, Good, (1,508 reviews)

7.8/10

Good

(1,508 reviews)

"Very convenient location Friendly and helpful staff"

"Very convenient location Friendly and helpful staff"

United States

Heather

The price is 2.314.283 ₫

2.314.283 ₫

2.591.998 ₫ total

includes taxes & fees

28 Sept - 29 Sept

La Quinta Inn & Suites by Wyndham Florence

A hotel room with two beds, a desk with a TV, and a bathroom visible through an open door.

A coffee station with two coffee machines, a coffee press, and various coffee-related items on a wooden counter.

A buffet with various food items, including omelets and baked goods, served in metal containers.

A large, two-story building with a central entrance flanked by columns, labeled "DIR FRANK B. LEE NURSING BUILDING."

18. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

2.5 star property

Florence

8.6 out of 10, Excellent, (1,001 reviews)

8.6/10

Excellent

(1,001 reviews)

"Good location- very good free breakfast"

"Good location- very good free breakfast"

United States

Christopher

The price is 3.194.802 ₫

3.194.802 ₫

3.835.320 ₫ total

includes taxes & fees

25 Oct - 26 Oct

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

An outdoor seating area with a fire pit, cushioned seating, and a pergola with string lights.

A modern lounge area with seating, tables, and a pool table.

A modern hotel restaurant with a breakfast bar, seating area, and a view of the city.

A modern hotel with a prominent 'TRU by Hilton' sign, a well-lit entrance, and a landscaped front yard.

19. Tru by Hilton Florence I-95

Tru by Hilton Florence I-95

2.5 star property

Florence

8.6 out of 10, Excellent, (1,001 reviews)

8.6/10

Excellent

(1,001 reviews)

"Excellent quick stay while traveling. Very clean room and easy check in and out."

"Excellent quick stay while traveling. Very clean room and easy check in and out."

United States

Tiffany

The price is 2.534.543 ₫

2.534.543 ₫

2.993.235 ₫ total

includes taxes & fees

26 Oct - 27 Oct

Tru by Hilton Florence I-95

A spacious hotel lobby with multiple seating areas, including tables and chairs, a reception desk, and a staircase leading to an upper level.

A lobby with leather sofas, a coffee table, potted plants, and a reception desk.

A Hampton Inn & Suites hotel with a well-lit entrance, multiple floors, and a parking area.

An indoor swimming pool with clear water, surrounded by a checkered wall pattern, and equipped with multiple seating areas and a lifeguard station.

20. Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95

2.5 star property

Florence

9.0 out of 10, Wonderful, (987 reviews)

9.0/10

Wonderful

(987 reviews)

"Nice stay"

"Nice stay"

United States

Michelle

The price is 3.067.010 ₫

3.067.010 ₫

3.435.050 ₫ total

includes taxes & fees

6 Oct - 7 Oct

Hampton Inn & Suites Florence-North-I-95

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Top Florence County Hotel Reviews

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

10/10 Excellent

"The front desk person was amazing!"

Debbie 1-night trip

Posted 10 hours ago

Park Inn by Radisson Florence, SC

Comfort Suites Florence I-95

Comfort Suites Florence I-95

10/10 Excellent

"Parfait"

Meyranie 1-night trip

Posted 14 hours ago

Comfort Suites Florence I-95

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

10/10 Excellent

"Rooms are clean, beds are comfortable, the shower is great!! Staff are great also!"

Dave 1-night trip

Posted 14 hours ago

Howard Johnson by Wyndham Florence

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

10/10 Excellent

"Stayed for a wedding nearby. It was perfect! The breakfast was also a huge plus with the fresh ground coffee."

Collin 2-night trip

Posted 2 days ago

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG

10/10 Excellent

"N/A"

Karen 1-night trip

Posted 2 days ago

Staybridge Suites Florence - Civic Center by IHG

Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

10/10 Excellent

"Great stay! Would definitely stay again!"

Vincent 1-night trip

Posted 2 days ago

Quality Inn & Suites Florence Civic Center

TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence

10/10 Excellent

"Many special touches were evident from the entrance to everything in my room, through breakfast and departure. The desk attendant recommended a wonderful Mexican restaurant only 3 minutes away. Absolutely amazing service!"

Ron 1-night trip

Posted 4 days ago

TownePlace Suites by Marriott Florence

Super 8 by Wyndham Florence

Super 8 by Wyndham Florence

8/10 Good

"Clean room, nice staff."

Agnes 1-night trip

Posted 4 days ago

Super 8 by Wyndham Florence

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

10/10 Excellent

"Very clean, nice staff and good breakfast"

Shanti 1-night trip

Posted 4 days ago

Hyatt Place Florence Downtown

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