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25 Dec - 26 Dec
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26 Dec - 27 Dec
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26 Dec - 28 Dec
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2 Jan - 4 Jan

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Our top choices for Grand Center hotels

Terrace/patio
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
4.0 star property
Grand Center
8.8 out of 10, Excellent, (1038)
"Great location and on-site food/beverage"
United States
Jennifer
The price is 3.136.867 ₫
3.699.275 ₫ total
includes taxes & fees
29 Dec - 30 Dec
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Front of property
Grand Center Inn

Grand Center Inn

Grand Center Inn
3.0 star property
Grand Center
9.4 out of 10, Exceptional, (73)
"Great! "
United States
mike
The price is 4.710.564 ₫
5.555.121 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Grand Center Inn
Lobby
White House at Grand Central

White House at Grand Central

White House at Grand Central
4.0 star property
Grand Center
8.6 out of 10, Excellent, (124)
"Very clean and very friendly people "
United States
Mary
The price is 1.711.066 ₫
3.693.450 ₫ total
includes taxes & fees
19 Jan - 20 Jan 2026
White House at Grand Central
Exterior
Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
2.5 star property
26.7 km from Grand Center
8.4 out of 10, Very good, (1001)
"Nice staff at reception. "
United States
Denise
The price is 2.070.407 ₫
2.379.457 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Comfort Suites St Charles - St Louis
Lobby
Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles
3.0 star property
26.5 km from Grand Center
9.6 out of 10, Exceptional, (1001)
"Staff and hotel were amazing"
United States
Allison
The price is 3.026.077 ₫
3.507.923 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Drury Plaza Hotel St. Louis St. Charles
Exterior
Hilton St. Louis Frontenac

Hilton St. Louis Frontenac

Hilton St. Louis Frontenac
4.0 star property
15.2 km from Grand Center
8.8 out of 10, Excellent, (1001)
"Great room, great amenities!"
United States
Linda or James
The price is 3.431.080 ₫
3.996.797 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton St. Louis Frontenac
Lobby
Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles
3.5 star property
27.5 km from Grand Center
8.8 out of 10, Excellent, (1006)
"Breakfast was excellent along with clean comfortable beds. "
United States
Scott
The price is 3.215.289 ₫
3.695.236 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Embassy Suites by Hilton St. Louis St. Charles
Free daily buffet breakfast
Hampton Inn & Suites St. Charles Old Town Area

Hampton Inn & Suites St. Charles Old Town Area

Hampton Inn & Suites St. Charles Old Town Area
2.5 star property
26.5 km from Grand Center
9.2 out of 10, Wonderful, (636)
"Huge room. Great breakfast. "
United States
David
The price is 2.851.911 ₫
3.437.790 ₫ total
includes taxes & fees
25 Jan - 26 Jan 2026
Hampton Inn & Suites St. Charles Old Town Area
Lobby sitting area
Best Western Plus The Charles Hotel

Best Western Plus The Charles Hotel

Best Western Plus The Charles Hotel
3.0 star property
26.9 km from Grand Center
8.2 out of 10, Very good, (1000)
"The room is decent for a night. The price is great and hotel staff is friendly. "
United States
Jordan
The price is 2.326.334 ₫
2.696.848 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Best Western Plus The Charles Hotel
Exterior
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
26.4 km from Grand Center
9.4 out of 10, Exceptional, (1001)
"Everything was great!"
United States
Rita
The price is 2.958.814 ₫
3.400.477 ₫ total
includes taxes & fees
25 Jan - 26 Jan 2026
Country Inn & Suites by Radisson, St. Charles Historic District
Exterior
Tru by Hilton St. Charles St. Louis, MO

Tru by Hilton St. Charles St. Louis, MO

Tru by Hilton St. Charles St. Louis, MO
2.5 star property
26.7 km from Grand Center
8.6 out of 10, Excellent, (772)
"Great hotel! "
United States
Royally
The price is 2.640.473 ₫
3.061.022 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Tru by Hilton St. Charles St. Louis, MO
Lobby
Best Western St. Louis-Kirkwood Route 66

Best Western St. Louis-Kirkwood Route 66

Best Western St. Louis-Kirkwood Route 66
3.5 star property
17.7 km from Grand Center
8.4 out of 10, Very good, (1370)
"Our stay was quiet and comfortable. Only a well used slightly stained bathtub kept this review from being excellent. "
United States
Lucinda
The price is 2.474.757 ₫
2.895.169 ₫ total
includes taxes & fees
30 Dec - 31 Dec
Best Western St. Louis-Kirkwood Route 66
Seasonal outdoor pool
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
26.1 km from Grand Center
8.4 out of 10, Very good, (1002)
"Clean room, wonderful helpful pleasant staff, amenities, everything was great love staying here!"
United States
Robyn
The price is 4.451.351 ₫
5.638.992 ₫ total
includes taxes & fees
29 Dec - 30 Dec
Ameristar Casino Resort and Spa
Room, 1 Queen Bed, Jetted Tub | Blackout curtains, free WiFi, bed sheets
Red Lion Inn & Suites Pontoon Beach

Red Lion Inn & Suites Pontoon Beach

Red Lion Inn & Suites Pontoon Beach
2.5 star property
19.3 km from Grand Center
7.8 out of 10, Good, (577)
"Yes, very good, yes good breakfast, yes truck parking."
United States
mark
The price is 1.539.486 ₫
1.742.909 ₫ total
includes taxes & fees
31 Dec - 1 Jan 2026
Red Lion Inn & Suites Pontoon Beach
Lobby
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
2.5 star property
16.2 km from Grand Center
9.4 out of 10, Exceptional, (2754)
"Great place to stay before your early morning flight. "
United States
Henry
The price is 2.368.177 ₫
2.787.917 ₫ total
includes taxes & fees
30 Dec - 31 Dec
Pear Tree Inn St. Louis Airport
Fridge, microwave, stovetop, dishwasher
Sonesta Simply Suites St Louis Earth City

Sonesta Simply Suites St Louis Earth City

Sonesta Simply Suites St Louis Earth City
2.0 star property
23.4 km from Grand Center
8.6 out of 10, Excellent, (805)
"Always a great stay"
United States
Darnell
The price is 2.105.280 ₫
2.420.820 ₫ total
includes taxes & fees
16 Jan - 17 Jan 2026
Sonesta Simply Suites St Louis Earth City
Lobby
Hampton Inn St. Louis - Columbia

Hampton Inn St. Louis - Columbia

Hampton Inn St. Louis - Columbia
2.5 star property
22.3 km from Grand Center
8.6 out of 10, Excellent, (476)
"Breakfast was great and a very good atten"
United States
John
The price is 2.588.601 ₫
2.872.829 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
Hampton Inn St. Louis - Columbia
Lobby
Motel 6 Hazelwood, MO

Motel 6 Hazelwood, MO

Motel 6 Hazelwood, MO
2.0 star property
20 km from Grand Center
8.4 out of 10, Very good, (1641)
"Great stay!"
United States
Ambrose
The price is 1.574.749 ₫
1.924.942 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
Motel 6 Hazelwood, MO
Breakfast, dinner and brunch served
The Principal Hotel

The Principal Hotel

The Principal Hotel
3.5 star property
22.5 km from Grand Center
9.8 out of 10, Exceptional, (193)
"Great place. Very nice rooms, new and clean."
United States
Jeff
The price is 2.968.708 ₫
3.294.763 ₫ total
includes taxes & fees
29 Dec - 30 Dec
The Principal Hotel
Free daily continental breakfast
Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport
2.5 star property
16.2 km from Grand Center
9.2 out of 10, Wonderful, (1504)
"Good transport to and from car rental, a plus "
United States
Ralph
The price is 2.840.812 ₫
3.344.763 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Wingate by Wyndham St. Louis Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Grand Center

Find the best Grand Center areas for the activities you enjoy most.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Busch Stadium to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

Berkeley

Visitors highly recommend Berkeley for its abundant dining options, and you can make a stop by James S. McDonnell Prologue Room while you're in town.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Saint Louis Abbey while you're in town.

Top Grand Center Hotel Reviews

White House at Grand Central

White House at Grand Central

10/10 Excellent
"The property was wonderful, perfect, beautiful. We loved it"
Xavier 2-night trip
Posted 1 month ago
White House at Grand Central

Frequently asked questions

What's it like in Grand Center?
Grand Center is a neighbourhood that travellers like for its theatre scene and opera houses. Make sure that you visit St. Louis Symphony Orchestra and Sheldon Concert Hall as part of your Grand Center travel plans.
How many hotels will I find in Grand Center?
Expedia has 31 hotels and other accommodation options in Grand Center to choose from, making this an ideal home base for exploring the greater St. Louis area.
If I need to cancel my hotel reservation in Grand Center, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If your reservation is non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of booking. Enter your dates, click on "Search", then filter by "fully refundable" to view the best options available in Grand Center.
What are the top things to see and do in Grand Center?
While you're in Grand Center, you can catch a show at St. Louis Symphony Orchestra, Sheldon Concert Hall and Fox Theater. Grandel Theater and Powell Hall are also a couple of places to visit in the neighbourhood. St. Louis Union Station and Busch Stadium are some popular places to visit in the area around Grand Center. While you're out sightseeing in St. Louis, make sure that you visit other sights such as Urban League St. Louis or Vaughn Cultural Center.