Search Hotels Near James S. McDonnell Prologue Room, St. Louis

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25 Dec - 26 Dec
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26 Dec - 27 Dec
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26 Dec - 28 Dec
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2 Jan - 4 Jan

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Our top choices for James S. McDonnell Prologue Room hotels

Pillow-top beds, in-room safe, desk, laptop workspace
Hyatt Select St. Louis Airport

Hyatt Select St. Louis Airport

Hyatt Select St. Louis Airport
2.5 star property
1.9 km from James S. McDonnell Prologue Room
9.2 out of 10, Wonderful, (1002)
"this is the perfect place to stay the night before going to the airport "
United States
Laurie
The price is 3.394.764 ₫
4.051.245 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Hyatt Select St. Louis Airport
Lobby
Drury Inn & Suites St. Louis Airport

Drury Inn & Suites St. Louis Airport

Drury Inn & Suites St. Louis Airport
3.0 star property
2 km from James S. McDonnell Prologue Room
9.2 out of 10, Wonderful, (1106)
"Everything was fantastic "
United States
Lynda
The price is 2.789.233 ₫
3.272.658 ₫ total
includes taxes & fees
30 Dec - 31 Dec
Drury Inn & Suites St. Louis Airport
Lobby
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
2.5 star property
2.6 km from James S. McDonnell Prologue Room
9.4 out of 10, Exceptional, (2755)
"Great place to stay before your early morning flight. "
United States
Henry
The price is 2.368.177 ₫
2.787.917 ₫ total
includes taxes & fees
30 Dec - 31 Dec
Pear Tree Inn St. Louis Airport
Room, 2 Queen Beds, Accessible, Non Smoking (Mobility, Tub W/Grab Bars) | Desk, laptop workspace, iron/ironing board, free cots/infant beds
Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport
2.5 star property
2.5 km from James S. McDonnell Prologue Room
9.2 out of 10, Wonderful, (1505)
"Good transport to and from car rental, a plus "
United States
Ralph
The price is 2.840.812 ₫
3.344.763 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Wingate by Wyndham St. Louis Airport
Terrace/patio
Hampton Inn By Hilton St Louis Airport

Hampton Inn By Hilton St Louis Airport

Hampton Inn By Hilton St Louis Airport
2.5 star property
2 km from James S. McDonnell Prologue Room
8.8 out of 10, Excellent, (105)
"Clen quiet and friendly staff"
United States
Howard
The price is 3.215.289 ₫
3.837.061 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Hampton Inn By Hilton St Louis Airport
Free daily buffet breakfast
Holiday Inn Express & Suites St Louis Airport by IHG

Holiday Inn Express & Suites St Louis Airport by IHG

Holiday Inn Express & Suites St Louis Airport by IHG
2.5 star property
2 km from James S. McDonnell Prologue Room
8.6 out of 10, Excellent, (1000)
"24 hour shuttle service was excellent. Great staff. "
United States
Jessica
The price is 3.105.288 ₫
3.811.053 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
Holiday Inn Express & Suites St Louis Airport by IHG
Exterior
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
4.0 star property
Berkeley, 2.1 km from James S. McDonnell Prologue Room
8.4 out of 10, Very good, (1064)
"I loved the service, room cleanliness, club lounge offered a nice variety of food and treats. The property is noticeably old but well maintained. "
United States
Ingrid I
The price is 3.210.552 ₫
3.755.960 ₫ total
includes taxes & fees
16 Jan - 17 Jan 2026
Renaissance St. Louis Airport Hotel
2 restaurants, breakfast, lunch, dinner served; American cuisine
Hilton St. Louis Airport

Hilton St. Louis Airport

Hilton St. Louis Airport
3.5 star property
1.9 km from James S. McDonnell Prologue Room
7.6 out of 10, Good, (1002)
"Great stay"
United States
Robert
The price is 3.021.077 ₫
3.605.293 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Hilton St. Louis Airport
Bar (on property)
DoubleTree by Hilton St. Louis Airport

DoubleTree by Hilton St. Louis Airport

DoubleTree by Hilton St. Louis Airport
4.0 star property
2.1 km from James S. McDonnell Prologue Room
7.8 out of 10, Good, (867)
"Great"
United States
Allyn
The price is 2.628.887 ₫
3.084.683 ₫ total
includes taxes & fees
25 Jan - 26 Jan 2026
DoubleTree by Hilton St. Louis Airport
Lobby
Marriott St. Louis Airport

Marriott St. Louis Airport

Marriott St. Louis Airport
4.0 star property
2.4 km from James S. McDonnell Prologue Room
8.0 out of 10, Very good, (1002)
"Love that there is a restaurant inside the property so that after you check in you do not have to go elsewhere to find a place to eat. "
United States
Susan
The price is 3.357.922 ₫
4.007.276 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Marriott St. Louis Airport
Breakfast area
Quality Inn Florissant - St Louis

Quality Inn Florissant - St Louis

Quality Inn Florissant - St Louis
2.5 star property
3.1 km from James S. McDonnell Prologue Room
7.6 out of 10, Good, (999)
"Hotel very old, not taken care of. Poor breakfast, OJ was rotten in the dispenser. Do not recommend "
United States
Thomas
The price is 1.752.646 ₫
2.070.135 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Quality Inn Florissant - St Louis
Exterior
Travelodge by Wyndham St. Louis

Travelodge by Wyndham St. Louis

Travelodge by Wyndham St. Louis
2.0 star property
Berkeley, 2.4 km from James S. McDonnell Prologue Room
6.6 out of 10, (1000)
"It was a nice and cheap stay"
United States
Levi
The price is 1.550.276 ₫
1.836.068 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Travelodge by Wyndham St. Louis
Blackout curtains, free WiFi, bed sheets
HomeTowne Studios by Red Roof St. Louis - Airport/ N Lindbergh

HomeTowne Studios by Red Roof St. Louis - Airport/ N Lindbergh

HomeTowne Studios by Red Roof St. Louis - Airport/ N Lindbergh
2.0 star property
2.9 km from James S. McDonnell Prologue Room
5.6 out of 10, (1000)
"Staff is so helpful and fridndly and the rooms re always clean. I wouldnt want to stay anywhere else."
United States
Samuel
The price is 1.965.542 ₫
2.402.388 ₫ total
includes taxes & fees
28 Dec - 29 Dec
HomeTowne Studios by Red Roof St. Louis - Airport/ N Lindbergh
Front of property
Welcome Suites Hazelwood

Welcome Suites Hazelwood

Welcome Suites Hazelwood
2.5 star property
3 km from James S. McDonnell Prologue Room
5.4 out of 10, (246)
"Clean rooms, full kitchens, they are currently updating everything, best prices in the area! Also the staff are great! "
United States
Lindsay
The price is 1.842.120 ₫
2.252.123 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Welcome Suites Hazelwood
Lobby
Quality Inn Saint Louis Airport

Quality Inn Saint Louis Airport

Quality Inn Saint Louis Airport
2.5 star property
2 km from James S. McDonnell Prologue Room
6.2 out of 10, (1004)
"Room not spotless but clean enough, staff courteous "
United States
Wynne
The price is 1.319.221 ₫
1.636.106 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Quality Inn Saint Louis Airport
Reception
Hilton Garden Inn St. Louis Airport

Hilton Garden Inn St. Louis Airport

Hilton Garden Inn St. Louis Airport
3.0 star property
Berkeley, 3.7 km from James S. McDonnell Prologue Room
8.4 out of 10, Very good, (1000)
"Great hotel staff!"
United States
Anissa
The price is 2.999.498 ₫
3.509.053 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Hilton Garden Inn St. Louis Airport
Suite, 1 King Bed, Non Smoking | Desk, blackout curtains, iron/ironing board, free WiFi
Comfort Inn & Suites St. Louis - Hazelwood

Comfort Inn & Suites St. Louis - Hazelwood

Comfort Inn & Suites St. Louis - Hazelwood
2.5 star property
3.4 km from James S. McDonnell Prologue Room
7.8 out of 10, Good, (606)
"Room was clean staff was friendly "
United States
Ella
The price is 2.053.437 ₫
2.510.080 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Comfort Inn & Suites St. Louis - Hazelwood
Deluxe Room, 1 King Bed, Non Smoking (Deluxe Executive Room) | Premium bedding, desk, laptop workspace, iron/ironing board
La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North

La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North

La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North
3.0 star property
3.6 km from James S. McDonnell Prologue Room
6.6 out of 10, (1000)
"Staff was great "
United States
Courtney
The price is 1.610.539 ₫
1.968.963 ₫ total
includes taxes & fees
28 Dec - 29 Dec
La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North
Lobby
Best Western St. Louis Airport North Hotel & Suites

Best Western St. Louis Airport North Hotel & Suites

Best Western St. Louis Airport North Hotel & Suites
2.5 star property
3.6 km from James S. McDonnell Prologue Room
7.4 out of 10, Good, (864)
"Friendly front desk"
United States
Phillip
The price is 2.001.858 ₫
2.447.032 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Best Western St. Louis Airport North Hotel & Suites
Meeting facility
Motel 6 Hazelwood, MO

Motel 6 Hazelwood, MO

Motel 6 Hazelwood, MO
2.0 star property
4.6 km from James S. McDonnell Prologue Room
8.4 out of 10, Very good, (1641)
"Great stay!"
United States
Ambrose
The price is 1.574.749 ₫
1.924.942 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
Motel 6 Hazelwood, MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top James S. McDonnell Prologue Room Hotel Reviews

Hampton Inn By Hilton St Louis Airport

Hampton Inn By Hilton St Louis Airport

10/10 Excellent
"Clen quiet and friendly staff"
Howard 3-night trip
Posted 4 days ago
Hampton Inn By Hilton St Louis Airport

Hotels near other James S. McDonnell Prologue Room attractions

Blacks in Flight Mural

You can enjoy some culture when you stop by Blacks in Flight Mural in St. Louis. Experience the area's acclaimed art galleries and great live music.
See properties

Bigfoot 4 x 4 Inc

2.6/5 (19 reviews)
You can spend time browsing the exhibits at Bigfoot 4 x 4 Inc in Hazelwood. Experience the great live music and acclaimed theatre scene in this family-friendly area.
See properties

Frequently asked questions

What's the area like around James S. McDonnell Prologue Room?
James S. McDonnell Prologue Room is located in a welcoming area of St. Louis known for its array of dining options and sporting events. You'll find 107 hotels and other accommodations within a few miles for a convenient home base.
How many hotels will I be able to find near James S. McDonnell Prologue Room?
Expedia has 107 hotels and other accommodation options a few miles from James S. McDonnell Prologue Room.
If I need to cancel the hotel reservation for my stay near James S. McDonnell Prologue Room, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within a 24-hour period of booking. Add your dates and click on "Search", then you can filter by "fully refundable" to view the best options available near James S. McDonnell Prologue Room.
What can I see and do near James S. McDonnell Prologue Room?
Payne-Gentry Historical House, St. Louis Car Museum and Museum of Transportation feature a variety of fascinating exhibits to see while you're in town. Attractions like Blanche M. Touhill Performing Arts Center and Blacks in Flight Mural highlight the local culture. Bigfoot 4 x 4 Inc, Old St. Ferdinand Shrine and St. Louis Mercantile Library are a few additional nearby sights.