The Best Hotels in Mission District, San Francisco - 2026 Updated Prices

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Compare popular hotels in Mission District

Property	Property class	Guest rating
Parker Guest House San Francisco	3.5 star property	9.6 Exceptional 491 reviews	View
Noe's Nest Bed and Breakfast	3.5 star property	9.4 Exceptional 133 reviews	View
1906 Mission	2.0 star property	8.0 Very good 201 reviews	View
Union Hotel	2.0 star property	7.0 Good 315 reviews	View
Hotel Sunrise	2.0 star property	6.8 673 reviews	View

Where to stay in Mission District

Find the best Mission District areas for the activities you enjoy most.

A street with shops, including a crystal shop and a crepes cafe.

Fisherman's Wharf

Travellers love Fisherman's Wharf for its popular shops, and you can see more of San Francisco by jumping on the metro at Jones St and Beach St Stop or Jefferson St & Taylor St Stop. You might spend time checking out top sights like Pier 39 and San Francisco Bay.

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A cityscape with tall buildings, a central plaza with palm trees, and a flag on one of the buildings.

Union Square

Known for its charming cafes and popular shops, there's plenty to explore in Union Square. Check out top attractions like Westin St Francis Hotel Glass Elevators and Union Square, and jump on the metro at Powell St & Geary Blvd Stop or Powell St & Post St Stop to see more of the city.

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A trolley on a street with buildings and a clock tower.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and San Francisco Bay are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

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A cityscape with modern skyscrapers, a central park with pathways, and a few people walking.

South of Market

Gourmet restaurants great entertainment and top sights from Oracle Park to San Francisco Bay – discover South of Market, a destination also famous for its shopping.

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A street lined with historic buildings, parked cars, and a clear blue sky.

Nob Hill

Gourmet restaurants Chinatown and top sights from SF Masonic Auditorium to Cable Car Museum – discover Nob Hill, a destination also famous for its shopping.

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Top Mission District Hotel Reviews

Hotel Riu Plaza Fisherman's Wharf

10/10 Excellent

"Lovely hotel, clean spacious rooms and friendly staff. Breakfast had so much choice and was great quality but very busy. Location was excellent. Would definitely return to stay again."

Hilton San Francisco Union Square

10/10 Excellent

"For me, the most impressive thing about the hotel was that when things went wrong the efforts and lengths that the staff went to to ensure that we still had a wonderful stay was unparalleled in my experience. Special recognition should go to Ryan on the front desk and Adriana who was the night manager when we had a serious issue. Even before we had our issue, Ryan had already given us a wonderful room, exactly as we had hoped it would be, with a fabulous city view. His approach is professional and British-style in its finesse! Credit where it is due! The hotel amenities were also very very good. I would absolutely choose this hotel again!"

Club Quarters Hotel in San Francisco

10/10 Excellent

"I stay at the Club Quarters every time I visit San Francisco. It's reliably clean and has what I need for a restful stay. There are parking garages caddy-corner from the property if you feel worried about parking on the street overnight, and Chinatown and little Italy are short walks also. Check-in is a little awkward because there is a self-serve kiosk, but staff is there to check IDs, direct payment, and activate room keys. Each floor has refillable water bottles by the elevators and a closet full of emergency needs like toothbrushes, shower caps, sewing kits, etc. Consistency is key, and Club Quarters is a reliably good night's stay."

Palace Hotel, a Luxury Collection Hotel, San Francisco

10/10 Excellent

"I had a great stay at the Palace Hotel, San Francisco. The hotel is beautiful, the rooms were clean and comfortable, and the staff was friendly and professional. The location is excellent and made it easy to explore the city. I would definitely stay here again and highly recommend it."

Frequently asked questions

What is Mission District like?

Mission District is a neighbourhood that travellers like for its bars. Are you looking for Mission District travel tips? Make sure that you visit San Francisco Public Library and Mission San Francisco de Asís while you're in the neighbourhood.

How many hotels will I be able to find in the Mission District area?

Expedia has 63 hotels and other accommodation options in Mission District to choose from, making this an ideal home base for exploring the greater San Francisco area.

If I need to cancel my hotel reservation in Mission District, will I receive a refund?

Yes, the majority of hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to cancel it and be given a refund within 24 hours of booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals available in Mission District.

What are the top things to see and do in Mission District?

Mission District's sights and attractions like The Chapel, Marsh Theater and Victoria Theatre offer insight into the local culture. San Francisco Public Library and Mission San Francisco de Asís are also a couple of places to visit in the neighbourhood. Oracle Park and Chase Center are some popular places to visit in the area around Mission District. While you're out sightseeing in San Francisco, make sure that you visit other sights such as Paxton Gate or Incline Gallery.

How can I get around Mission District and the greater San Francisco area?

For a quick way to explore the city, catch a ride on metro transit at 16th Street Mission Station, 24th Street Mission Station or Right Of Way/20th St Stop.

Search Hotels in Mission District, San Francisco

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Our top choices for Mission District hotels

1. Parker Guest House San Francisco

2. 1906 Mission

3. Union Hotel

4. Noe's Nest Bed and Breakfast

5. Hotel Sunrise

6. Holiday Inn Golden Gateway by IHG

7. Handlery Union Square Hotel

8. YOTEL San Francisco

9. Hotel Nikko San Francisco

10. LUMA Hotel San Francisco

11. Stanford Court San Francisco

12. King George Hotel

13. Hotel Riu Plaza Fisherman's Wharf

14. Club Quarters Hotel in San Francisco

15. Hilton San Francisco Union Square

16. The Pickwick Hotel

17. The Marker Union Square San Francisco

18. Chancellor Hotel on Union Square

19. Hyatt Place San Francisco Downtown

20. Galleria Park Hotel

Compare popular hotels in Mission District

Where to stay in Mission District

Fisherman's Wharf

Union Square

Downtown San Francisco

South of Market

Nob Hill

Top Mission District Hotel Reviews

Hotel Riu Plaza Fisherman's Wharf

Frequently asked questions

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