Search Hotels in Otay Mesa West, San Diego

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Our top choices for Otay Mesa West hotels

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
31.2 km from Otay Mesa West
9.4 out of 10, Exceptional, (1,928 reviews)
"It is a perfect hotel if breakfast is included in the stay."
United States
Tugba
The price is 2.598.307 ₫
3.174.362 ₫ total
includes taxes & fees
26 May - 27 May
Sycuan Casino Resort

Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
10.5 km from Otay Mesa West
9.2 out of 10, Wonderful, (3,826 reviews)
"Great resort "
United States
Ines
The price is 3.926.448 ₫
4.326.735 ₫ total
includes taxes & fees
20 May - 21 May
Best Western Plus Marina Gateway Hotel

Comfort Inn Chula Vista San Diego South

Comfort Inn Chula Vista San Diego South
2.5 star property
7.9 km from Otay Mesa West
8.2 out of 10, Very good, (1,500 reviews)
"We really enjoyed our stay here! Breakfast in the morning was great & staff was always friendly & helpful!"
United States
Megan
The price is 2.746.142 ₫
3.026.248 ₫ total
includes taxes & fees
14 Jun - 15 Jun
Comfort Inn Chula Vista San Diego South

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2.5 star property
11 km from Otay Mesa West
8.2 out of 10, Very good, (1,737 reviews)
"great breakfast and nice staff"
United States
rosita
The price is 3.425.760 ₫
3.896.934 ₫ total
includes taxes & fees
7 Jun - 8 Jun
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Days Inn by Wyndham San Diego-East/El Cajon

Days Inn by Wyndham San Diego-East/El Cajon
2.0 star property
27 km from Otay Mesa West
7.8 out of 10, Good, (1,004 reviews)
"Great place definitely recommend"
United States
Trenton
The price is 2.105.868 ₫
2.320.561 ₫ total
includes taxes & fees
21 May - 22 May
Days Inn by Wyndham San Diego-East/El Cajon

Hampton Inn & Suites San Diego Airport Liberty Station

Hampton Inn & Suites San Diego Airport Liberty Station
2.5 star property
22.4 km from Otay Mesa West
9.2 out of 10, Wonderful, (1,721 reviews)
"Staff are very helpful and nearby places to eat are accessible, also near to the airport!"
United States
Mercyditha De
The price is 4.614.762 ₫
5.304.437 ₫ total
includes taxes & fees
25 May - 26 May
Hampton Inn & Suites San Diego Airport Liberty Station

Best Western Americana Inn

Best Western Americana Inn
2.5 star property
2.1 km from Otay Mesa West
9.0 out of 10, Wonderful, (1,286 reviews)
"Everything was very pleasant,the place was super clean, and the breakfast was delicious👍"
United States
Nancy
The price is 3.223.377 ₫
3.666.591 ₫ total
includes taxes & fees
25 May - 26 May
Best Western Americana Inn

Ayres Hotel San Diego South - Chula Vista

Ayres Hotel San Diego South - Chula Vista
3.0 star property
9.2 km from Otay Mesa West
9.8 out of 10, Exceptional, (1,099 reviews)
"Clean room & location is great close to every thing"
United States
Giselle
The price is 4.956.811 ₫
5.462.242 ₫ total
includes taxes & fees
1 Jun - 2 Jun
Ayres Hotel San Diego South - Chula Vista

La Quinta Inn by Wyndham San Diego Chula Vista

La Quinta Inn by Wyndham San Diego Chula Vista
3.0 star property
7.8 km from Otay Mesa West
8.6 out of 10, Excellent, (1,619 reviews)
"Great stay"
United States
Helda
The price is 2.777.501 ₫
3.055.252 ₫ total
includes taxes & fees
31 May - 1 Jun
La Quinta Inn by Wyndham San Diego Chula Vista

The Alcala Hotel Mission Valley/Seaworld

The Alcala Hotel Mission Valley/Seaworld
2.5 star property
24 km from Otay Mesa West
8.0 out of 10, Very good, (66 reviews)
"Awesome and friendly staff! Breakfast was great 😊 "
United States
jason
The price is 2.185.898 ₫
2.512.663 ₫ total
includes taxes & fees
26 May - 27 May
The Alcala Hotel Mission Valley/Seaworld

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
21.4 km from Otay Mesa West
8.4 out of 10, Very good, (3,534 reviews)
"Excellent food, friendly staff, easy check-in, and beautiful setting. "
United States
Emily
The price is 4.084.715 ₫
6.028.110 ₫ total
includes taxes & fees
27 May - 28 May
Sheraton San Diego Resort

Best Western Plus La Mesa San Diego

Best Western Plus La Mesa San Diego
2.5 star property
23.2 km from Otay Mesa West
8.4 out of 10, Very good, (1,007 reviews)
"Clean room, clean property, kind staff, great breakfast, very spacious rooms."
United States
Sergio
The price is 3.449.740 ₫
3.794.714 ₫ total
includes taxes & fees
25 May - 26 May
Best Western Plus La Mesa San Diego

Pleasant Inn

Pleasant Inn
2.5 star property
30.7 km from Otay Mesa West
8.6 out of 10, Excellent, (1,408 reviews)
"Staff was very friendly and helpful. Good location for sights we wanted to see."
United States
Steve
The price is 2.419.114 ₫
2.775.920 ₫ total
includes taxes & fees
21 May - 22 May
Pleasant Inn

Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG
2.5 star property
22.4 km from Otay Mesa West
9.2 out of 10, Wonderful, (1,059 reviews)
"Staff was so great nice rooms really great stay"
United States
Amelia
The price is 4.163.616 ₫
4.785.868 ₫ total
includes taxes & fees
25 May - 26 May
Holiday Inn Express San Diego Airport - Old Town by IHG

Courtyard by Marriott San Diego El Cajon

Courtyard by Marriott San Diego El Cajon
3.0 star property
25.8 km from Otay Mesa West
9.2 out of 10, Wonderful, (1,002 reviews)
"Really nice staff and great hotel!"
Canada
Shana
The price is 3.875.852 ₫
4.270.995 ₫ total
includes taxes & fees
25 May - 26 May
Courtyard by Marriott San Diego El Cajon

California Suites Hotel

California Suites Hotel
2.0 star property
30.6 km from Otay Mesa West
7.8 out of 10, Good, (2,547 reviews)
"Very comfortable, nice pool and hot tub, quiet, pretty location, and close to lots of stuff! Would stay here again! "
United States
Stephon
The price is 2.039.645 ₫
2.340.493 ₫ total
includes taxes & fees
20 May - 21 May
California Suites Hotel

TownePlace Suites by Marriott San Diego Airport/Liberty Station

TownePlace Suites by Marriott San Diego Airport/Liberty Station
3.0 star property
22.4 km from Otay Mesa West
9.0 out of 10, Wonderful, (1,005 reviews)
"Love it great place"
United States
Derek
The price is 4.457.441 ₫
5.123.605 ₫ total
includes taxes & fees
25 May - 26 May
TownePlace Suites by Marriott San Diego Airport/Liberty Station

Lamplighter Inn & Suites at SDSU

Lamplighter Inn & Suites at SDSU
2.5 star property
21 km from Otay Mesa West
9.0 out of 10, Wonderful, (1,425 reviews)
"Great location good continental breakfast."
United States
Michael
The price is 3.507.451 ₫
3.954.644 ₫ total
includes taxes & fees
20 May - 21 May
Lamplighter Inn & Suites at SDSU

Heritage Inn San Diego

Heritage Inn San Diego
2.0 star property
25.2 km from Otay Mesa West
7.4 out of 10, Good, (1,453 reviews)
"I really like the hotel Was close to sea world and lots of eating places with in walking distance."
United States
Latrice
The price is 1.861.505 ₫
2.139.782 ₫ total
includes taxes & fees
20 May - 21 May
Heritage Inn San Diego

GreenTree Inn San Diego Mission Bay

GreenTree Inn San Diego Mission Bay
2.5 star property
Pacific Beach, 29.3 km from Otay Mesa West
8.0 out of 10, Very good, (2,108 reviews)
"Great experience, will stay here again"
United States
Victoria
The price is 2.540.069 ₫
2.919.682 ₫ total
includes taxes & fees
27 May - 28 May
GreenTree Inn San Diego Mission Bay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Otay Mesa West

Find the best Otay Mesa West areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Pacific Beach while you're exploring the area.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Gaslamp Quarter

Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Lyceum Theatre – discover Gaslamp Quarter, a destination also famous for its shopping.

Mission Bay

If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.

Top Otay Mesa West Hotel Reviews

Frequently asked questions

What is Otay Mesa West like?
Otay Mesa West is a neighbourhood that travellers like for its cathedral.
If I need to cancel my hotel reservation in Otay Mesa West, will I receive a refund?
Yes! The majority of room reservations are refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to review top deals in Otay Mesa West.
What is there to do around this San Diego neighbourhood?
A few places to visit in the area around Otay Mesa West include San Ysidro Border Crossing, Las Americas Premium Outlets and Sesame Place San Diego. While you're out sightseeing in San Diego, make sure that you visit other sights such as Tijuana Customs - Garita El Chaparral or North Island Credit Union Amphitheatre.
How can I get around Otay Mesa West and the greater San Diego area?
Ready to get out and explore the city? Iris Avenue Trolley Station is the closest metro station.