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Our top choices for San Sisto holiday rentals

Townhouse in Corciano

L'Antica Sosta
9.4 out of 10, Exceptional, (3)
"Molto accoglienti e gentili "
Italy
Valentina
The price is 1.834.510 ₫
2.017.961 ₫ total
includes taxes & fees
15 Dec - 16 Dec
L'Antica Sosta

Apartment in Old Town Perugia

Welchome suites
9.2 out of 10, Wonderful, (15)
"Great location and host was extremely helpful and quick to communicate. "
United States
Jenifer
The price is 2.419.608 ₫
2.754.221 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Welchome suites
10.0 out of 10, Exceptional, (3)
"Great place! "
United States
Carlos
The price is 2.350.119 ₫
2.893.971 ₫ total
includes taxes & fees
21 Dec - 22 Dec
PianPieve Nature and Relax apartments

Holiday Home in Perugia

Etruscan Residence Perugia
10.0 out of 10, Exceptional, (1)
The price is 3.639.835 ₫
8.387.495 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Etruscan Residence Perugia

Aparthotel in Assisi Historic Center

Suite Assisi
Suite Assisi

Aparthotel in Gualdo Cattaneo

Aethos Saragano
9.4 out of 10, Exceptional, (30)
"This hotel is a gem! The staff was amazing! The continental breakfast was very good! Our room was amazing! Would highly recommend staying here on your next trip to the Umbria region! "
Canada
Chantal
Aethos Saragano

Townhouse in Valfabbrica

Castello di Giomici
9.2 out of 10, Wonderful, (52)
"We booked the stay last minute, not really knowing what to expect. We were happily surprised to find a 900 year old castle on the top of the hill, with its own church (which we were given the keys to see ourselves), towers and old hallways. The house was on 3 floors with 4 bedrooms, perfect for the 4 adults and 4 kids in our group, plus a rooftop with amazing views. The staff were super friendly and welcoming. Considering the price, it might be the best value for money place I've ever stayed...
United Kingdom
Mark
The price is 1.671.527 ₫
1.838.680 ₫ total
includes taxes & fees
13 Jan - 14 Jan 2026
Castello di Giomici

Holiday Home in Spello

Terre del Cantico Country House
8.0 out of 10, Very good, (4)
"Très bon établissement proche de Spello"
France
CAROLINE
Terre del Cantico Country House

Aparthotel in Gubbio

Tenuta Borgo San Michele
9.2 out of 10, Wonderful, (5)
"Un posto davvero tranquillo immenso nel verde. Colazione abbondante e variegata. Gentilissimo il signore alla reception che ci ha dato consigli per vivere al meglio il nostro soggiorno."
Italy
Laura
The price is 1.915.257 ₫
2.230.319 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Tenuta Borgo San Michele

Townhouse in Assisi Historic Center

Le Dimore della Custodia
9.6 out of 10, Exceptional, (7)
"Amazing, felt like I could move here. Quiet, clean, spacious, great view, peaceful"
United States
Richard
The price is 3.026.633 ₫
3.452.832 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Le Dimore della Custodia

Holiday Home in Castiglione del Lago

Poggio del Sole
8.0 out of 10, Very good, (4)
"El hotel no alcanzó el agua caliente y no se pudo bañar parte de la familia no contaba con suficientes amenidades "
Mexico
RAUL
Poggio del Sole
10.0 out of 10, Exceptional, (12)
"Property was excellent, perfect location for our visit, friendly staff, Elisabetta was really helpful and provided tips about the city during our visit to Assisi. "
United States
IVAN
The price is 2.053.787 ₫
2.382.702 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
Il Granaio di Rossetti Elisabetta

Townhouse in Assisi

Domus Angeli Camere
8.4 out of 10, Very good, (6)
"Great stay, very convenient location"
United Kingdom
Patrick
The price is 2.526.898 ₫
2.903.124 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Domus Angeli Camere

Apartment in Spello

La Terrazza di spello
8.2 out of 10, Very good, (22)
"Increíble estancia en el alojamiento en Spello. Es muy espacioso y cercano del centro. Hermoso para caminar"
Spain
Gonzalo Martín
La Terrazza di spello

Residence in Perugia

Castello di Monterone
9.8 out of 10, Exceptional, (301)
"Staff was great, the castle itself is incredible."
United States
Kevin
Castello di Monterone

Apartment in Bastia Umbra

I Casali della Ghisleria
8.4 out of 10, Very good, (5)
"Excellent customer service. They stayed connected even though we checked in late. I would come back and plan to stay longer as the grounds have a beautiful pool and garden. "
Canada
Delia
I Casali della Ghisleria
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top San Sisto Hotel Reviews

Frequently asked questions

Are there holiday rentals in San Sisto?

Yes, there are holiday rentals in San Sisto close to Perugina Chocolate Factory, or you can select a more secluded option if you're looking for a relaxing stay.

How many holiday rentals will I find in San Sisto?

With 3 Expedia holiday rentals, you're guaranteed to find just the right place for your San Sisto stay.

What’s there to see and do in San Sisto?

Explore the area and family-friendly sights such as Perugina Chocolate Factory, or get out into nature at a spot like Lake Trasimeno. Renato Curi Stadium and Citta della Domenica are a couple of places you'll find in the wider area.

What’s a holiday rental in San Sisto like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in San Sisto. Holiday rentals feature amenities such as WiFi and washers and dryers so your stay will be comfortable. If you're concerned about a clean environment, a holiday rental can offer a sense of safety away from public hotel lifts and busy lobbies while still allowing you the enjoyment of travel. You'll also have more space in a holiday rental than in a traditional hotel, which is another reason why a holiday rental is an attractive choice for a family getaway.