Santa Clara Holidays
Book a Hotel + Flight or Car together to unlock savings
Top hotels in Santa Clara
Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
The price is 3.406.254 ₫ per night from 5 May to 6 May
3.406.254 ₫
3.746.879 ₫ total
5 May - 6 May
includes taxes & fees
9/10 Wonderful! (5,261 reviews)
My number one Hotel in Panama City ! Close to everything and Uber is cheap
Reviewed on 10 Apr 2026
Sheraton Grand Panama
Via Israel And 77th Street Panama City Panama
Fully refundableReserve now, pay when you stay
The price is 3.334.188 ₫ per night from 1 May to 2 May
3.334.188 ₫
3.667.607 ₫ total
1 May - 2 May
includes taxes & fees
8.6/10 Excellent! (1,003 reviews)
Fresh breakfast each morning
Reviewed on 9 Apr 2026
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Via Espana 111 Panama City Panama
Fully refundableReserve now, pay when you stay
The price is 3.001.164 ₫ per night from 12 Apr to 13 Apr
3.001.164 ₫
3.301.280 ₫ total
12 Apr - 13 Apr
includes taxes & fees
7.8/10 Good! (1,008 reviews)
Very nice Hotel. The staff are exceptionally friendly and really care. They were very good to us.
Reviewed on 9 Apr 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
Culebra Cut
You can learn about the history of Santa Clara when you stop by Culebra Cut. Visit the casinos and top-notch restaurants in this walkable area.
