Panama Holidays

Book a Hotel + Flight or Car together to unlock savings

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Top destinations in Panama

A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

Panama City

Panama City
A waterfront area with buildings, boats, and a dock.

Bocas del Toro

Bocas del Toro
A beach with waves, a boat, and palm trees.

Rio Hato

Rio Hato
A staircase leading to a building with a yellow facade, surrounded by greenery and a large stone statue.

Bastimentos

Bastimentos
A bridge with illuminated arches at dusk.

Boquete

Boquete
A group of women in white dresses with lace details, dancing outdoors.

Veracruz

Veracruz
A historic stone fortress with a central dome and surrounding walls.

Colon

Colon

Top hotels in Panama

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
3.440.947 ₫
3.785.042 ₫ total
28 Sept - 29 Sept
includes taxes & fees
9/10 Wonderful! (5,865 reviews)
"The breakfast was excellent and the staff was great. All in all, the hotel is an A+"

Reviewed on 29 Aug 2026

Hotel Riu Plaza Panama
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

Ave. Domingo Diaz Tocumen Panama
Fully refundable
3.077.794 ₫
3.557.721 ₫ total
26 Sept - 27 Sept
includes taxes & fees
8.6/10 Excellent! (2,685 reviews)
"Staff was friendly."

Reviewed on 29 Aug 2026

Crowne Plaza Panama Airport by IHG
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Plaza de la Independencia Casco Viejo Panama City Panama
Fully refundableReserve now, pay when you stay
4.782.705 ₫
5.260.976 ₫ total
27 Sept - 28 Sept
includes taxes & fees
9.2/10 Wonderful! (1,007 reviews)
"Don’t expect to sleep Upon checkin I was out in my “Jr Suite”. It was just a room. But worse, I tried to soon and heard a rhythmic banging that was impossible to sleep through. It was so bad that I decided to see what it was. My room was DIRECTLY UNDER the gym, in a centuries old building?! If anyone ..."

Reviewed on 29 Aug 2026

Central Hotel Panama Casco Viejo
See all 3,853 properties in Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Panama holiday package cost?
Custom build your Panama holiday package from a low . Choose from any combination of rental cars, flights and hotels to pull together the trip you've been dreaming about. Remember to add on some activities and experiences!
How do I get a cheap travel package to Panama?
One of the easiest ways to save cash (and time) is to combine your bookings with Expedia. Hotels, flights, rental cars and activities — we've got them all. Select the combination that suits you and watch your savings stack up. Of course, a package deal is never one-size-fits-all. That's why we offer over 550 airlines and 1null000null000 hotels worldwide, which lets you customize your Panama holiday.
Where should I stay in Panama?
Panama City is a great place to visit. It draws in many visitors who come to check out its biggest sights, such as Bridge of the Americas and Miraflores Locks.
What are the top hotels in Panama?
When it comes to hotels in Panama City, Hotel Riu Plaza Panama and Crowne Plaza Panama Airport, an IHG Hotel are two terrific options. If you're also visiting Bocas del Toro, Playa Tortuga Hotel Beach And Resort and Azul Paradise will make you feel at home.
How far in advance should I book my Panama holiday?
It's difficult to pick the ideal time for airfares, but we usually say the earlier, the better. Most international journeys on Expedia become available up to 12 months in advance. If you're booking last minute, fear not. Discounted prices appear from time to time just weeks before departure dates.
What does an Expedia Panama travel package include?
Hotels, rental cars and flights, or any combination of them — it's up to you! Whether you're venturing to Panama with the kids or travelling solo, there's a package to fit your budget and style. Once you've made your booking, why not add on one or two tours or activities?
What should I know before booking a Panama travel package?
A travel package can be customized for your budget and is a terrific way to make your hard-earned dollars stretch further. How much you include is up to you. Rental cars, hotels and flights — come up with a combination that suits your plans.
Can I choose my airline with a Panama Expedia holiday package?
Yes — and it's simple too. Expedia has access to more than 550 partner airlines all over the world. Our packages give you the flexibility to pick from available flights, hotels and activities that fit your needs.
If I'm not able to travel, can I cancel my Panama holiday package?
Because we know life is full of surprises, the answer is yes. For further information, head to our Customer Service Portal. But generally speaking, if you've made your booking in the last 24 hours, you may be able to change or cancel it for free. Your airline, hotel or car rental company may impose a fee if you made your booking a while ago.

Stay near popular Panama attractions

A coastal cityscape with a beach, palm trees, and high-rise buildings during sunset.

Playa Blanca

8.2/10 (527 reviews)
Nothing says holiday like spending a lazy day at Playa Blanca, a popular beach in Rio Hato. Amble around this family-friendly area's seaside or experience its entertainment venues.
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A modern building facade with vertical reflective panels and the word "GUCCI" prominently displayed.
Photo by Fabiola Tile

Multiplaza Pacific Mall

9.0/10 (4,497 reviews)
During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.
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A marina with numerous boats, a bridge in the background, and lush green hills.

Amador Causeway

9.0/10 (1,902 reviews)
You can learn about the history of Ancon with a visit to Amador Causeway. Stroll along the seaside or visit the shops in this vibrant area.
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A city skyline with tall buildings along a waterfront.
Photo by Rob Gosse

Cinta Costera

9.2/10 (3,823 reviews)
After visiting Cinta Costera, make a plan to see the other sights and activities in Panama City. While you're in the area, stroll along the seaside.
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A nighttime cityscape with illuminated skyscrapers and a river reflecting the lights.

Avenida Balboa

8.8/10 (3,608 reviews)
You can browse for the perfect souvenirs at Avenida Balboa during your stay in Panama City. While you're in the area, wander around the natural setting.
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A beach lined with palm trees and flowers under a clear blue sky.

Farallón Beach

8.0/10 (255 reviews)
If a restful holiday is part of your travel plans, Farallón Beach might be the perfect place to visit during your trip to El Farallón del Chirú. While you're here, you can savour the top-notch restaurants.
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Albrook Shopping Mall

8.6/10 (4,561 reviews)
You can find the perfect gifts to bring home with a trip to Albrook Shopping Mall, a favourite shopping spot in Ancon. Amble around this culturally rich area's seaside and enjoy its top-notch restaurants.
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Venao Beach

9.2/10 (137 reviews)
If a restful holiday is part of your travel plans, Venao Beach might be the perfect place to visit during your trip to Las Escobas del Venado. You can seek out the surfing spots while in the area.
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