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Check prices for these dates

Tonight
16 Dec - 17 Dec
Tomorrow
17 Dec - 18 Dec
This weekend
19 Dec - 21 Dec
Next weekend
26 Dec - 28 Dec

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Our top choices for Santa Cruz hotels

Terrace/patio
Las Casas de la Judería, Sevilla Historic City Center

Las Casas de la Judería, Sevilla Historic City Center

Las Casas de la Judería, Sevilla Historic City Center
4.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (1007)
"The property had real historic character - in a great location with helpful and friendly staff "
United Kingdom
Caroline Jane
The price is 3.189.673 ₫
3.508.640 ₫ total
includes taxes & fees
13 Jan - 14 Jan 2026
Las Casas de la Judería, Sevilla Historic City Center
Seasonal outdoor pool, open noon to 9 PM, pool umbrellas, pool loungers
Hotel Fernando III

Hotel Fernando III

Hotel Fernando III
4.0 star property
Santa Cruz
9.6 out of 10, Exceptional, (1530)
"Great location & staff were wonderful!"
United States
Fawn
Hotel Fernando III
Lobby sitting area
Hotel Amadeus Sevilla

Hotel Amadeus Sevilla

Hotel Amadeus Sevilla
4.0 star property
Santa Cruz
9.6 out of 10, Exceptional, (1085)
"A great spot with a wonderful staff and breakfast"
Canada
Don
The price is 3.436.548 ₫
3.780.203 ₫ total
includes taxes & fees
13 Jan - 14 Jan 2026
Hotel Amadeus Sevilla
Lobby
Hotel Alcántara

Hotel Alcántara

Hotel Alcántara
2.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (827)
"24 hour front desk is very helpful; very good location close to major attractions while still quiet; very friendly staff."
Canada
WEN LI
The price is 1.405.736 ₫
1.546.309 ₫ total
includes taxes & fees
13 Jan - 14 Jan 2026
Hotel Alcántara
Suite (Balcón Rosina) | Living area
Suites Murillo Plaza Sta Cruz

Suites Murillo Plaza Sta Cruz

Suites Murillo Plaza Sta Cruz
3.5 star property
Santa Cruz
9.8 out of 10, Exceptional, (216)
"This hotel is amazing, the location is perfect, from the time we checked in everyone was so nice and helpful. Our room was perfect, the coffee provided was delicious, we had been traveling for a while and this hotel was just what we needed, everything was so comfortable, it was perfect. "
United States
daniel
Suites Murillo Plaza Sta Cruz
View from property
Hotel Murillo

Hotel Murillo

Hotel Murillo
2.0 star property
Santa Cruz
8.8 out of 10, Excellent, (1003)
"Staff was very friendly, perfect location can’t get any better than this hotel"
United States
Aldon
Hotel Murillo
Courtyard
El Rey Moro Hotel Boutique

El Rey Moro Hotel Boutique

El Rey Moro Hotel Boutique
4.0 star property
Santa Cruz
9.4 out of 10, Exceptional, (892)
"The location is A+! The staff is extremely attentive and knowledgeable their rooms where pristine and comfortable. The bed is very good. Breakfast is amazing. This hotel delivers a great experience."
United States
WALDECTOR
The price is 2.905.998 ₫
3.196.598 ₫ total
includes taxes & fees
17 Dec - 18 Dec
El Rey Moro Hotel Boutique
Terrace/patio
Basic Hotel Doña Manuela

Basic Hotel Doña Manuela

Basic Hotel Doña Manuela
2.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (518)
"Clean good staff happy stay great location "
United Kingdom
A. Caroline
Basic Hotel Doña Manuela
Porch
Hotel Boutique Palacio Pinello

Hotel Boutique Palacio Pinello

Hotel Boutique Palacio Pinello
4.0 star property
Santa Cruz
9.4 out of 10, Exceptional, (682)
"The hotel is centric"
United States
javier
The price is 2.843.803 ₫
3.128.183 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Hotel Boutique Palacio Pinello
Reception
Petit Palace Santa Cruz

Petit Palace Santa Cruz

Petit Palace Santa Cruz
4.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (1004)
"We like the location, staff was nice and helpful, clean. "
United States
Alla
The price is 2.365.853 ₫
2.602.438 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Petit Palace Santa Cruz
Panoramic Penthouse, Terrace, City View (Pool) | Premium bedding, down duvets, in-room safe, individually decorated
Hotel Boutique Corral del Rey by ALUZ Collection

Hotel Boutique Corral del Rey by ALUZ Collection

Hotel Boutique Corral del Rey by ALUZ Collection
3.0 star property
Santa Cruz
9.6 out of 10, Exceptional, (95)
"Staff was extremely helpful and always very pleasant."
United States
Gregory Carroll
The price is 5.622.677 ₫
6.184.945 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Hotel Boutique Corral del Rey by ALUZ Collection
Exclusive Duplex, 1 Bedroom, Private Pool | Terrace/patio
Welldone Cathedral

Welldone Cathedral

Welldone Cathedral
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (323)
"Great location, clean room, safe and quiet. "
United States
Yolanda
The price is 2.687.380 ₫
2.956.118 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Welldone Cathedral
Rooftop terrace
Hotel Rey Alfonso X

Hotel Rey Alfonso X

Hotel Rey Alfonso X
4.0 star property
Santa Cruz
9.6 out of 10, Exceptional, (1115)
"Thoroughly enjoyed our stay and would highly recommend. Staff were very friendly and helpful and the breakfast very tasty! "
United Kingdom
John
The price is 9.574.043 ₫
10.531.447 ₫ total
includes taxes & fees
29 Dec - 30 Dec
Hotel Rey Alfonso X
Interior entrance
Hotel Casa de Colón

Hotel Casa de Colón

Hotel Casa de Colón
3.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (330)
"What a beautiful hotel right in the heart of Seville. My room was spotless , the bed so comfortable and the staff were so friendly and helpful. I had breakfast on the terrace and in the lobby …both were delicious. A wonderful place to stay "
United Kingdom
Sue
The price is 2.331.525 ₫
2.564.708 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
Hotel Casa de Colón
Terrace/patio
Suites Murillo Catedral

Suites Murillo Catedral

Suites Murillo Catedral
3.5 star property
Santa Cruz
9.4 out of 10, Exceptional, (630)
"Great location and property is clean"
United States
Sreedevi
Suites Murillo Catedral
Regional cuisine
Hotel Convento La Gloria

Hotel Convento La Gloria

Hotel Convento La Gloria
3.0 star property
Santa Cruz
8.2 out of 10, Very good, (633)
"Excelent hotel"
United States
osvaldo
Hotel Convento La Gloria
Exterior
Hotel Boutique Casa del Poeta Sevilla

Hotel Boutique Casa del Poeta Sevilla

Hotel Boutique Casa del Poeta Sevilla
4.0 star property
Santa Cruz
9.8 out of 10, Exceptional, (865)
"The hotel was centrally located and The staff was a pleasure and informative . The room was spacious and clean .. perfect overnight stay "
United States
isabel
The price is 5.527.536 ₫
6.080.290 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Hotel Boutique Casa del Poeta Sevilla
Exterior
Casa Palacio La Casa Blanca Suites

Casa Palacio La Casa Blanca Suites

Casa Palacio La Casa Blanca Suites
3.0 star property
Santa Cruz
9.6 out of 10, Exceptional, (357)
"Amazing place in a perfect location! "
Canada
Olga
The price is 5.458.047 ₫
6.003.852 ₫ total
includes taxes & fees
16 Jan - 17 Jan 2026
Casa Palacio La Casa Blanca Suites
Interior detail
Legado Alcázar Hotel

Legado Alcázar Hotel

Legado Alcázar Hotel
4.0 star property
Santa Cruz
9.8 out of 10, Exceptional, (963)
"Staff super nice and a clean room"
United States
Karla
The price is 2.960.255 ₫
3.256.219 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
Legado Alcázar Hotel
Terrace/patio
Eurostars Sevilla Boutique

Eurostars Sevilla Boutique

Eurostars Sevilla Boutique
4.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (489)
"Room was spotless, staff was courteous and location was perfect!"
United States
Andrean
The price is 2.783.048 ₫
3.061.384 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Eurostars Sevilla Boutique
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Santa Cruz

Find the best Santa Cruz areas for the activities you enjoy most.

Historical Center

Known for its fantastic nightlife, stunning cathedral and popular shops, there's plenty to explore in Historical Center. Top attractions like Casa de la Memoria Cultural Center and Calle Sierpes are major draws. Catch the metro at Plaza Nueva Tram Stop or Archivo de Indias Tram Stop to see more of the city.

Alfalfa

Unique features of Alfalfa include the bars and historical sites. Make a stop by Calle Sierpes or Casa de la Memoria Cultural Center while you're exploring the area.

El Arenal

Travellers choose El Arenal for its abundant dining options. Hop aboard the metro at Plaza Nueva Tram Stop or Archivo de Indias Tram Stop and check out top sights like Teatro Maestranza.

Triana featuring a river or creek, street scenes and a house

Triana

Known for its abundant dining options and stunning river views, there's plenty to explore in Triana. Top attractions like Triana Market and Triana Bridge are major draws, and you can catch the metro at Plaza de Cuba Station or Cartuja Station to see more of the city.

Cerro-Amate

Check out the restaurants during your time in Cerro-Amate. Hop around the Seville area on the metro at Amate Station to see top sights like Centro Deportivo Amate and Circuito de Automodelismo.

Top Santa Cruz Hotel Reviews

Explore a world of travel with Expedia

Frequently asked questions

What is Santa Cruz like?
Santa Cruz is an historic neighbourhood known for its charming cafes and bar scene. Make sure that you visit Convent of the Incarnation and Giralda Tower as part of your Santa Cruz travel plans.
How many hotels are there in the Santa Cruz area?
If you're searching for places to stay in Paseo de Las Delicias, Expedia has something to meet your needs with 439 Santa Cruz hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes, most hotel bookings are fully refundable if you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to get the best options available in Santa Cruz.
What can I see and do in this Paseo de Las Delicias neighbourhood?
Explore Santa Cruz's landmarks such as Seville Cathedral, Giralda Tower and General Archive of the Indies and learn about the local history. You could also plan a visit to Convent of the Incarnation or Archbishop's Palace while you're in the neighbourhood. A few places to visit in the area around Santa Cruz include Archiddiocesis de Sevilla, Triunfo Plaza and Tumba de Cristóbal Colón. While you're out sightseeing in Paseo de Las Delicias, make sure that you visit other sights such as Puerta del Príncipe or El Giraldillo.
How can I get around Santa Cruz and the greater Paseo de Las Delicias area?
Ready to get out and explore the city? Puerta Jerez Tram Stop is the closest metro station.