Southern Indiana Holidays

Book a Hotel + Flight or Car together to unlock savings

Where to stay in Southern Indiana

Find the best Southern Indiana areas and neighborhoods for the activities you enjoy most. Learn more about Southern Indiana
Louisville Science Center which includes outdoor art

West Main Historic District

A noteworthy feature of West Main Historic District is its fantastic nightlife. While you're in town, be sure to stop and check out Frazier International History Museum and Louisville Slugger Museum.

Find hotels in West Main Historic District

Top hotels in Southern Indiana

Radisson Hotel Louisville North

Radisson Hotel Louisville North

3 out of 5
505 Marriott Drive, Clarksville, IN
Fully refundable
The price is 1.557.547 ₫ per night from 24 Sept to 25 Sept
1.557.547 ₫
1.760.028 ₫ total
24 Sept - 25 Sept
includes taxes & fees
6.8/10 (2,279 reviews)
"Everything was good"

Reviewed on 22 Aug 2025

Radisson Hotel Louisville North
Sheraton Louisville Riverside by Marriott

Sheraton Louisville Riverside by Marriott

3.5 out of 5
700 West Riverside Drive, Jeffersonville, IN
Fully refundableReserve now, pay when you stay
The price is 2.451.294 ₫ per night from 31 Aug to 1 Sept
2.451.294 ₫
2.769.961 ₫ total
31 Aug - 1 Sept
includes taxes & fees
8.2/10 Very Good! (1,003 reviews)
A little outdated, the staff makes up for it!
"Its outdated some but mot terrible. The staff went above and beyond!!"

Reviewed on 17 Aug 2025

Sheraton Louisville Riverside by Marriott
Hyatt Place Evansville

Hyatt Place Evansville

3 out of 5
202 Se 2nd St, Evansville, IN
Fully refundableReserve now, pay when you stay
The price is 3.031.170 ₫ per night from 1 Sept to 2 Sept
3.031.170 ₫
3.485.846 ₫ total
1 Sept - 2 Sept
includes taxes & fees
9.4/10 Exceptional! (1,000 reviews)
"Excellent"

Reviewed on 20 Aug 2025

Hyatt Place Evansville
See all 1,452 properties in Southern Indiana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Holiday World and Splashin' Safari

Holiday World and Splashin' Safari

Bring the children to Holiday World and Splashin' Safari and have a fun-filled day at this theme park in Santa Claus. Discover the area's jazz scene and temples.

Holiday World and Splashin' Safari
Louisville Slugger Museum featuring interior views

Louisville Slugger Museum

4.5/5(3 reviews)

You can spend an afternoon studying the exhibits at Louisville Slugger Museum during your travels in Louisville. Amble around the area's riverfront or attend a sporting event.

Louisville Slugger Museum
Whiskey Row

Whiskey Row

Learn about the local history of Louisville with a stop at Whiskey Row. Attend a sporting event or simply enjoy the lively bars while you're in the area.

Whiskey Row

Frequently asked questions

How much does a Southern Indiana holiday package cost?
We make it simple to travel somewhere new, with Southern Indiana holiday packages starting from just . You'll have the flexibility to combine your preferred airlines, hotels and car rental. For the ultimate escape, why not add a few activities and tours to your itinerary?
How do I get a cheap travel package to Southern Indiana?
If you love bargains, combine your bookings into a Southern Indiana holiday package. Whether you're looking for flights, hotels, day tours or rental cars, you can book everything in one place. You'll have plenty of choice at your fingertips too. Expedia has over 550 airlines and 1null000null000 hotels around the globe to take your pick of. Fly with who you want, stay where you like and save a packet — now that's the ideal getaway!
Where should I stay in Southern Indiana?
Louisville is a fantastic place to explore. It draws in many travellers who come to see its top sights, like Churchill Downs and Muhammad Ali Centre.
What are the top hotels in Southern Indiana?
When it comes to properties in Louisville, Galt House Hotel Trademark Collection by Wyndham and Radisson Hotel Louisville Jeffersonville are two fantastic options. If you're also spending time in Jeffersonville - Clarksville, Radisson Hotel Louisville Jeffersonville and JW Marriott Indianapolis look forward to welcoming you.
How far in advance should I book my Southern Indiana holiday?
It all depends on the airline, but you can normally browse through international airfares on Expedia up to a year in advance. While it's a good idea to book ahead of time, lucky travellers will sometimes score a cheaper seat only weeks before the date of departure.
What does an Expedia Southern Indiana travel package include?
With Expedia, you can select any combination of flights, car rentals and hotels to create your ideal Southern Indiana travel package. Once you've made your booking, you can add on all the fun stuff like sightseeing tours and activities. Remember — the more you bundle, the greater the savings!
What should I know before booking a Southern Indiana travel package?
You'll save plenty with an Expedia travel package. Combine your airfares, rental cars and hotels and land fabulous discounts. Hotels aren't your only choice, though. Book with us and select from island resorts, rural cottages and everything in between!
Can I choose my airline with a Southern Indiana Expedia holiday package?
Expedia offers access to more than 550 partner airlines globally, so you certainly can. Simply select the carrier that suits you and create the perfect Southern Indiana trip.
If I'm not able to travel, can I cancel my Southern Indiana holiday package?
Yes, you can. We understand that even the best-laid plans can go awry, so we're here to help if you have to make changes to your Southern Indiana holiday package. You may be able to amend or cancel your itinerary at no cost if you've booked in the last 24 hours. Your hotel, airline or car rental company may impose a fee if your booking was made more than 24 hours ago. Have a look at our Customer Service Portal for more information. Also, be sure to check your itinerary for the finer details on change fees.