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Search Business Hotels in Southwest Illinois

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Check availability on Southwest Illinois Business Hotels

Tonight
3 Dec - 4 Dec
Tomorrow
4 Dec - 5 Dec
This weekend
5 Dec - 7 Dec
Next weekend
12 Dec - 14 Dec

Top Southwest Illinois Business Hotels

Exterior
Drury Inn & Suites Marion

Drury Inn & Suites Marion

3.0 star property
Marion
9.4 out of 10, Exceptional, (1012)
"Great hotel and very clean "
United States
Jose
The price is 1.713.721 ₫
2.056.254 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Drury Inn & Suites Marion
Free daily buffet breakfast
Holiday Inn Express Hotel & Suites Marion Northeast by IHG

Holiday Inn Express Hotel & Suites Marion Northeast by IHG

2.5 star property
Marion
9.0 out of 10, Wonderful, (924)
"yes the room was great and the staff was great! "
United States
Amador
The price is 2.405.400 ₫
2.885.999 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Holiday Inn Express Hotel & Suites Marion Northeast by IHG
Lobby
Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

3.0 star property
Mount Vernon
9.6 out of 10, Exceptional, (1568)
"Great place to stay. Check in is easy and the hotel people are very nice."
United States
Duane
The price is 2.478.422 ₫
2.803.292 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Drury Plaza Hotel Mt. Vernon
Terrace/patio
Comfort Suites Mount Vernon

Comfort Suites Mount Vernon

2.5 star property
Mount Vernon
9.0 out of 10, Wonderful, (1004)
"Good location, good breakfast"
United States
Don
The price is 2.975.100 ₫
3.354.516 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Comfort Suites Mount Vernon
Exterior
Holiday Inn Carbondale-Conference Center by IHG

Holiday Inn Carbondale-Conference Center by IHG

3.0 star property
Carbondale
8.8 out of 10, Excellent, (639)
"Great staff!"
United States
Greg
The price is 2.510.900 ₫
2.887.033 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Holiday Inn Carbondale-Conference Center by IHG
Room, 1 Queen Bed, Accessible, Non Smoking | Desk, blackout curtains, iron/ironing board, free cots/infant beds
Super 8 by Wyndham Mt. Vernon IL

Super 8 by Wyndham Mt. Vernon IL

2.5 star property
Mount Vernon
7.8 out of 10, Good, (1003)
"Clean comfortable room and bed. Great location to many restaurants and shopping. "
United States
Patricia
The price is 1.501.715 ₫
1.719.340 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Super 8 by Wyndham Mt. Vernon IL
Lobby
SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake

2.5 star property
Whittington
8.8 out of 10, Excellent, (901)
"Great place to stay."
United States
Stephen
The price is 1.905.330 ₫
2.114.535 ₫ total
includes taxes & fees
31 Dec - 1 Jan 2026
SureStay Hotel by Best Western Whittington Rend Lake
Front of property – evening/night
Hampton Inn Carbondale

Hampton Inn Carbondale

2.5 star property
Carbondale
8.4 out of 10, Very good, (611)
"Room was spotless, check in was quick, all personnel were courteous. "
United States
William
The price is 2.616.400 ₫
3.008.336 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Hampton Inn Carbondale
Lobby sitting area
Baymont by Wyndham Marion

Baymont by Wyndham Marion

2.5 star property
Marion
8.4 out of 10, Very good, (1063)
"This place was nice for the money and our 1 night stay. "
United States
Charles
The price is 1.860.333 ₫
2.232.136 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Baymont by Wyndham Marion
Desk, blackout curtains, iron/ironing board, free WiFi
Comfort Inn & Suites Greenville I-70

Comfort Inn & Suites Greenville I-70

2.5 star property
Greenville
8.4 out of 10, Very good, (413)
"Room was clean and comfortable."
United States
Michael
The price is 2.353.969 ₫
2.612.434 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Comfort Inn & Suites Greenville I-70
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southwest Illinois Hotel Reviews

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Frequently asked questions

How much do business-friendly hotels in Southwest Illinois cost?
You'll pay between 1.719.340 ₫ and 3.354.516 ₫ per night for business-friendly hotels in Southwest Illinois. Top deals on stays that cater to work-related travellers are only a click away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in Southwest Illinois?
There are multiple business-friendly hotels in Southwest Illinois with a total average guest review rating of 8.7, so you're sure to discover the perfect place. On your way to O'Fallon? Drury Inn & Suites St. Louis O'Fallon, IL is a top pick with corporate travellers. This 3-stars option has amenities like a swimming pool and WiFi. Hampton Inn O'Fallon also scores top marks from business guests. Take advantage of a swimming pool and an electric car charging station at this 2.5-stars escape in O'Fallon.
How many business-friendly hotels are there in Southwest Illinois?
Southwest Illinois has 105 business-friendly hotels to choose from. Whether you're attending a conference or meeting or simply working remotely, these properties are equipped with the amenities you need to keep you comfortable and productive.
What are the best cheap business-friendly hotels in Southwest Illinois?
When you need to make and close deals on the go in Southwest Illinois, Expedia will help you find the perfect business-friendly hotel. Hampton Inn O'Fallon is a popular budget option in O'Fallon. An electric car charging station and a swimming pool are among its many amenities. In search of low-cost stays in Marion? Comfort Inn & Suites Marion I-57 is recommended by many corporate guests. It comes with conveniences that make it easy to both work and relax, including pool sun loungers and a swimming pool. Business-friendly hotels in Southwest Illinois start at just 1.719.340 ₫ a night. Like to sightsee around Southwest Illinois without the high admission prices? Take a break from your work commitments to visit awesome free attractions like St. Clair Bowl in O'Fallon. Marion also has many things to do that don't cost a penny, including Williamson County Historical Museum. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
Are there any family-friendly hotels in Southwest Illinois that are also business friendly?
If you're travelling for business in Southwest Illinois and bringing family along with you, Expedia will help you locate a cosy and convenient stay. Drury Inn & Suites St. Louis O'Fallon, IL in O'Fallon is the perfect option for those combining work and pleasure. This 3-stars property comes with all the necessary amenities, like complimentary breakfast and a laundry service. Drury Inn & Suites St. Louis Fairview Heights is another terrific choice in O'Fallon. Get the best of both worlds — combine corporate travel and quality time with your family at this 3-stars property. Complimentary breakfast and WiFi are among the conveniences you'll find here. Once you've gotten work out of the way, get out and see O'Fallon with the kids. Popular family-friendly attractions include The Edge and St. Clair Bowl.
Why book your business-friendly hotel in Southwest Illinois with Expedia?
At Expedia, our top task is to help you land the ideal stay at the right price. From upmarket, corporate-friendly properties to affordable motels filled with all the amenities you need, you'll have your next work trip arranged in a few simple clicks.
How can I find cheap business-friendly hotels in Southwest Illinois?
When work takes you to Southwest Illinois, our "business friendly" filter will help you find a suitable hotel. From fast WiFi to meeting rooms and workspaces, they come with the amenities you need for a comfortable and productive stay. Another tip? Narrow your search by your budget and preferred star rating to see the cheapest accommodation.
What is there to do in Southwest Illinois near my business-friendly hotel?
Wherever your travels take you in Southwest Illinois, there's plenty to keep you busy. Staying a few days in O'Fallon? The Edge is a top attraction to include on your itinerary.