Southwest Illinois Holidays
Book a Hotel + Flight or Car together to unlock savings
Photo by Southernmost Illinois Tourism Bureau
Where to stay in Southwest Illinois
Find the best Southwest Illinois areas and neighborhoods for the activities you enjoy most. Learn more about Southwest Illinois
Eastport
While visiting Eastport, you might make a stop by sights like Gateway Conference Center and Splash City Family Waterpark.
Top hotels in Southwest Illinois
Drury Inn & Suites St. Louis Fairview Heights
12 Ludwig Dr Fairview Heights IL
The price is 2.469.775 ₫ per night from 15 Mar to 16 Mar
2.469.775 ₫
2.790.352 ₫ total
15 Mar - 16 Mar
includes taxes & fees
9.2/10 Wonderful! (1,020 reviews)
Didn't visit
Reviewed on 9 Mar 2026
Drury Inn & Suites St. Louis O'Fallon, IL
1118 Central Park Drive O'Fallon IL
Fully refundableReserve now, pay when you stay
The price is 2.778.422 ₫ per night from 15 Mar to 16 Mar
2.778.422 ₫
3.222.413 ₫ total
15 Mar - 16 Mar
includes taxes & fees
9.6/10 Exceptional! (1,017 reviews)
The room was comfortable, and clean. The beds had plenty of pillows and a comfortable bed. The check in process was quick. The room had a clean bathroom and shower, with plenty of towels for us. The only issue I would bring up is that there was only 1 operational elevator which meant a delay in getting ...
Reviewed on 9 Mar 2026
Drury Plaza Hotel Mt. Vernon
145 North 44th Street Mount Vernon IL
Fully refundableReserve now, pay when you stay
The price is 2.942.761 ₫ per night from 5 Apr to 6 Apr
2.942.761 ₫
3.318.430 ₫ total
5 Apr - 6 Apr
includes taxes & fees
9.6/10 Exceptional! (1,667 reviews)
I booked for 3/9-3/10/26. We arrived today and were told the reservation was for last night. I’m Very clear that I selected a stay fo tonight. I have no idea how it got changed to last night. Please refund me in full for the incorrect reservation last night.
Reviewed on 9 Mar 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
Southern Illinois University
Enjoy the student vibe when you visit Southern Illinois University during your trip to Carbondale. Visit the shops and top-notch restaurants in this family-friendly area.
DuQuoin State Fairgrounds
Catch an event at DuQuoin State Fairgrounds during your trip to Du Quoin. Experience the area's festivals and live music.
Gateway Conference Center
Gateway Conference Center is just one of the places to see in Collinsville, so why not enjoy the other things to explore during your travels? Discover the top-notch restaurants and great live music in this walkable area.
