Southwest Illinois Holidays

Book a Hotel + Flight or Car together to unlock savings

Photo by Southernmost Illinois Tourism Bureau

Where to stay in Southwest Illinois

Find the best Southwest Illinois areas and neighborhoods for the activities you enjoy most. Learn more about Southwest Illinois
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Eastport

While visiting Eastport, you might make a stop by sights like Splash City Family Waterpark and Gateway Conference Center.

Find hotels in Eastport

Top hotels in Southwest Illinois

Drury Plaza Hotel Mt. Vernon
Drury Plaza Hotel Mt. Vernon
3 out of 5
145 North 44th Street , Mount Vernon, IL
Fully refundableReserve now, pay when you stay
The price is 2.462.632 ₫ per night from 27 Jul to 28 Jul
2.462.632 ₫
2.785.430 ₫ total
27 Jul - 28 Jul
includes taxes & fees
9.6/10 Exceptional! (1,374 reviews)
"The hotel had been beautifully renovated. The lobby, restaurant/bar was excellent. The free breakfast offered full breakfast, not continental. The daily kickback with free drinks and food is a great plus. The rooms were clean and had comfy bed. The staff from front desk, restaurant to housekeeping ..."

Reviewed on 1 Jul 2025

Drury Plaza Hotel Mt. Vernon
Quality Inn & Suites near St. Louis and I-255
Quality Inn & Suites near St. Louis and I-255
2.5 out of 5
1607 Pontiac Dr, East St. Louis, IL
Fully refundableReserve now, pay when you stay
The price is 1.904.289 ₫ per night from 27 Jul to 28 Jul
1.904.289 ₫
2.151.847 ₫ total
27 Jul - 28 Jul
includes taxes & fees
7.4/10 Good! (999 reviews)
"Gvg"

Reviewed on 30 Jun 2025

Quality Inn & Suites near St. Louis and I-255
Best Western Plus Pontoon Beach
Best Western Plus Pontoon Beach
3 out of 5
4 Regency Pkwy, Granite City, IL
Fully refundableReserve now, pay when you stay
The price is 2.472.236 ₫ per night from 7 Jul to 8 Jul
2.472.236 ₫
2.743.687 ₫ total
7 Jul - 8 Jul
includes taxes & fees
8.4/10 Very Good! (683 reviews)
"Close parking, excellent staff, very accommodating of accessibility requests, quiet area."

Reviewed on 30 Jun 2025

Best Western Plus Pontoon Beach
See all 675 properties in Southwest Illinois
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Southern Illinois University

Southern Illinois University

Enjoy the student vibe when you visit Southern Illinois University during your trip to Carbondale. Visit the shops and top-notch restaurants in this family-friendly area.

Southern Illinois University
Cahokia Mounds State Historic Site

Cahokia Mounds State Historic Site

You can learn about the history of Collinsville with a trip to Cahokia Mounds State Historic Site. Discover the great live music in this walkable area or seek out the local tours.

Cahokia Mounds State Historic Site
Southern Illinois featuring autumn colours and forests

Tunnel Hill State Trail

You can take time to visit Tunnel Hill State Trail during your travels to Vienna. Amble around the area's parks or experience its museums.

Tunnel Hill State Trail

Frequently asked questions

How much does a Southwest Illinois holiday package cost?
Explore the best of Southwest Illinois from just . Choose from a great selection of flights, rental cars and hotels to suit every budget and style. Land even more discounts when you add some experiences or tours to your package.
How do I get a cheap travel package to Southwest Illinois?
Search for flights that fit your busy schedule, add a hotel to your booking and see how much you save with a Southwest Illinois holiday package. It's as simple as that! From flights and hotels to rental cars and activities, Expedia makes travelling on the cheap easy. And with more than 550 partner airlines and 1null000null000 hotels all over the world to choose from, you'll never be short of choice.
What are the top hotels in Southwest Illinois?
Check out Super 8 by Wyndham Carbondale and Best Western Saluki Inn. They're top picks for many travellers headed to Carbondale. If Marion features in your travel plans, Super 8 by Wyndham Marion and Quality Inn And Suites are a couple of cosy options.
How far in advance should I book my Southwest Illinois holiday?
It can be hard to know exactly when is the ideal time to book your Southwest Illinois trip. But generally the earlier you book, the lower the prices. Sometimes, you can reserve your flights and hotels up to a year prior to departure. If you're thinking of a last-minute getaway, no need to panic! There are unbeatable bargains popping up on Expedia every single day.
What does an Expedia Southwest Illinois travel package include?
With Expedia, you can choose any combination of hotels, flights and car rentals to create your perfect Southwest Illinois package. Once you've made your booking, you can add on the fun things like tours and activities. Don't forget --- the more you bundle, the more you'll save!
What should I know before booking a Southwest Illinois travel package?
Discover deals that match your budget with an Expedia package. Flights, hotels, rental cars --- we have everything you need to plan your break. You'll save a tidy sum just by combining your bookings. Whether you're taking off on a winter adventure or venturing someplace warm, your ideal holiday is just clicks away.
Can I choose my airline with a Southwest Illinois Expedia holiday package?
You can, and with more than 550 airlines to pick from across the globe, you're not short on choice. Scroll through the available options and find out which airline fits your budget and needs.
If I'm not able to travel, can I cancel my Southwest Illinois holiday package?
If your holiday plans in Southwest Illinois have been upended, it's a relief to know that it's possible to amend or cancel your booking. If you booked less than 24 hours ago, you may be able to get a refund. If your booking was made more than 24 hours ago, your airline, hotel or car rental company may charge fees. To find out more, check our Customer Service Portal.