Southwest Illinois Holidays
Book a Hotel + Flight or Car together to unlock savings
Photo by Southernmost Illinois Tourism Bureau
Where to stay in Southwest Illinois
Find the best Southwest Illinois areas and neighborhoods for the activities you enjoy most. Learn more about Southwest Illinois
Eastport
While visiting Eastport, you might make a stop by sights like Gateway Conference Center and Splash City Family Waterpark.
Top hotels in Southwest Illinois
Drury Plaza Hotel Mt. Vernon
145 North 44th Street Mount Vernon IL
Fully refundableReserve now, pay when you stay
The price is 2.478.046 ₫ per night from 7 Dec to 8 Dec
2.478.046 ₫
2.802.865 ₫ total
7 Dec - 8 Dec
includes taxes & fees
9.6/10 Exceptional! (1,559 reviews)
Everything was great. Clean rooms, great customer service from the front desk to the kitchen staff. We will stay here again!
Reviewed on 29 Nov 2025
Quality Inn & Suites near St. Louis and I-255
1607 Pontiac Dr East St. Louis IL
Fully refundableReserve now, pay when you stay
The price is 1.773.837 ₫ per night from 21 Dec to 22 Dec
1.773.837 ₫
2.004.436 ₫ total
21 Dec - 22 Dec
includes taxes & fees
7.4/10 Good! (1,004 reviews)
Great place to stop for the night on a trip. The bed was comfortable. I didn't use the Internet much, but it seemed to work. Breakfast had cereal, eggs & sausage, waffles, yogurt, toast, and juice. Not a fancy place, but very good for my needs.
Reviewed on 20 Nov 2025
Super 8 by Wyndham O'Fallon
1100 Eastgate Dr O'Fallon IL
Fully refundableReserve now, pay when you stay
The price is 1.120.512 ₫ per night from 14 Dec to 15 Dec
1.120.512 ₫
1.288.365 ₫ total
14 Dec - 15 Dec
includes taxes & fees
7/10 Good! (1,020 reviews)
Lots of choices for the breakfast.
Reviewed on 25 Nov 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
Southern Illinois University
Enjoy the student vibe when you visit Southern Illinois University during your trip to Carbondale. Visit the shops and top-notch restaurants in this family-friendly area.
Tunnel Hill State Trail
You can take time to visit Tunnel Hill State Trail during your travels to Vienna. Amble around the area's parks or experience its museums.
Marion Cultural and Civic Center
Marion Cultural and Civic Center is just one of the places to see in Marion, so why not enjoy the other things to explore during your travels? While you're here, you can savour the top-notch restaurants.
