Search Hotels in Tenderloin, San Francisco

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Tenderloin hotels

Hotel EPIK

Hotel EPIK
4.0 star property
Tenderloin
7.0 out of 10, Good, (554)
"Friendly staff - Very convenient- Amazingly quiet ."
United States
Antonio
The price is 2.204.744 ₫
2.594.873 ₫ total
includes taxes & fees
29 Dec - 30 Dec
Hotel EPIK

Embassy Hotel

Embassy Hotel
2.5 star property
Tenderloin
6.8 out of 10, (506)
"What a gem to stay will stay on next trip"
United States
tony
Embassy Hotel

Best Western Red Coach Inn

Best Western Red Coach Inn
2.5 star property
Tenderloin
8.0 out of 10, Very good, (783)
"Clean; conveniently located."
United States
Joyce
The price is 3.019.761 ₫
3.548.219 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Best Western Red Coach Inn

Motel 6 San Francisco, CA – Civic Center

Motel 6 San Francisco, CA – Civic Center
2.0 star property
Tenderloin
7.2 out of 10, Good, (487)
"Clean rooms and comfy bed"
United States
Warren
The price is 1.894.489 ₫
2.229.755 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Motel 6 San Francisco, CA – Civic Center

Alexis Park Hotel

Alexis Park Hotel
2.0 star property
Tenderloin
7.2 out of 10, Good, (1000)
"The room was clean and the staff was friendly :)"
United States
Tamariah
The price is 2.210.544 ₫
2.597.389 ₫ total
includes taxes & fees
30 Dec - 31 Dec
Alexis Park Hotel

Courtyard by Marriott San Francisco Downtown/Van Ness Ave.

Courtyard by Marriott San Francisco Downtown/Van Ness Ave.
3.0 star property
Tenderloin
9.0 out of 10, Wonderful, (533)
"Staff very friendly and helpful."
United States
Catherine
The price is 4.447.404 ₫
5.234.372 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Courtyard by Marriott San Francisco Downtown/Van Ness Ave.

Cathedral Hill Hotel

Cathedral Hill Hotel
2.0 star property
Tenderloin
7.2 out of 10, Good, (657)
"Located betwixt Chinatown and The Tenderloin, this local establishment provides a value that is worth putting up any quirks you may find in your room. "
United States
Riley
The price is 1.973.437 ₫
2.322.913 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Cathedral Hill Hotel

The Phoenix Hotel

The Phoenix Hotel
3.0 star property
Tenderloin
9.0 out of 10, Wonderful, (1000)
"Fun hotel; clean and comfortable!"
United States
Kim
The price is 3.528.976 ₫
4.153.455 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
The Phoenix Hotel

Bay Hotel

Bay Hotel
2.0 star property
Tenderloin
5.2 out of 10, (598)
"Staff was nice. Hotel is noisy."
United States
Mark
The price is 1.776.330 ₫
2.087.188 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Bay Hotel

Admiral Hotel

Admiral Hotel
2.0 star property
Tenderloin
6.6 out of 10, (177)
"Nostalgic old Hotel,Amazing ambiance,comfortable rooms and super friendly staff…"
United States
Scot
Admiral Hotel

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf
4.0 star property
Fisherman's Wharf, 2.5 km from Tenderloin
9.0 out of 10, Wonderful, (7217)
"Great place to stay!"
United States
Isaiah
The price is 2.723.016 ₫
4.289.073 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Hotel Riu Plaza Fisherman's Wharf

The Westin San Francisco Airport

The Westin San Francisco Airport
4.0 star property
20.3 km from Tenderloin
8.8 out of 10, Excellent, (2014)
"Comfortable room, welcome glass of wine, easy shuttle to and from airport, friendly staff."
United States
Carole
The price is 2.708.443 ₫
3.883.540 ₫ total
includes taxes & fees
28 Dec - 29 Dec
The Westin San Francisco Airport

Hilton San Francisco Airport Bayfront

Hilton San Francisco Airport Bayfront
4.0 star property
22.5 km from Tenderloin
8.6 out of 10, Excellent, (2761)
"Nice airport hotel…staff was great, breakfast was amazing "
United States
Lynne
The price is 2.760.022 ₫
3.137.920 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Hilton San Francisco Airport Bayfront

Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco
4.0 star property
Financial District, 1.7 km from Tenderloin
8.8 out of 10, Excellent, (2821)
"Clean room, friendly staff and good location"
United States
Jose Eduardo
The price is 2.638.968 ₫
3.106.077 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Club Quarters Hotel in San Francisco

Hilton San Francisco Financial District

Hilton San Francisco Financial District
4.0 star property
Financial District, 1.4 km from Tenderloin
8.6 out of 10, Excellent, (2173)
"Great hotel "
United States
Tanya
The price is 2.891.602 ₫
3.403.271 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton San Francisco Financial District

Hotel Caza Fisherman's Wharf

Hotel Caza Fisherman's Wharf
4.0 star property
Fisherman's Wharf, 2.5 km from Tenderloin
9.0 out of 10, Wonderful, (3826)
"Excellent stay and great location! "
United States
CHRISTINE
The price is 3.200.947 ₫
4.975.258 ₫ total
includes taxes & fees
24 Jan - 25 Jan 2026
Hotel Caza Fisherman's Wharf

Chancellor Hotel on Union Square

Chancellor Hotel on Union Square
3.5 star property
0.7 km from Tenderloin
9.4 out of 10, Exceptional, (3094)
"Great hotel, great location, super friendly all staff "
Mexico
Claudia
The price is 1.993.173 ₫
2.355.136 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Chancellor Hotel on Union Square

Aloft San Francisco Airport

Aloft San Francisco Airport
3.0 star property
20.5 km from Tenderloin
9.0 out of 10, Wonderful, (2235)
"All good, friendly staff, spotless room. "
United States
Michael
The price is 2.732.653 ₫
3.141.048 ₫ total
includes taxes & fees
29 Dec - 30 Dec
Aloft San Francisco Airport

FOUND Hotel Carlton, Nob Hill

FOUND Hotel Carlton, Nob Hill
2.0 star property
0.5 km from Tenderloin
8.6 out of 10, Excellent, (1133)
"such clean rooms & wonderful staff they are very helpful felt so comfortable in my stay!"
United States
heidi
The price is 1.891.093 ₫
2.225.722 ₫ total
includes taxes & fees
25 Jan - 26 Jan 2026
FOUND Hotel Carlton, Nob Hill

Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG
3.5 star property
Nob Hill, 0.9 km from Tenderloin
9.0 out of 10, Wonderful, (5029)
"Rooms were great, staff was great, location was great. "
United States
Jonathan
The price is 2.947.392 ₫
3.468.933 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Holiday Inn Golden Gateway by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Tenderloin

Find the best Tenderloin areas for the activities you enjoy most.

Union Square

Known for its charming cafes and popular shops, there's plenty to explore in Union Square. Check out top attractions like Westin St Francis Hotel Glass Elevators and Union Square, and jump on the metro at Powell St & Geary Blvd Stop or Powell St & Post St Stop to see more of the city.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and Chase Center are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

Fisherman's Wharf

Travellers love Fisherman's Wharf for its popular shops, and you can see more of San Francisco by jumping on the metro at Jones St and Beach St Stop or Jefferson St & Taylor St Stop. You might spend time checking out top sights like Pier 39 and San Francisco Bay.

South of Market

Gourmet restaurants great entertainment and top sights from Oracle Park to Chase Center – discover South of Market, a destination also famous for its shopping.

Nob Hill

Gourmet restaurants Chinatown and top sights from SF Masonic Auditorium to Cable Car Museum – discover Nob Hill, a destination also famous for its shopping.

Top Tenderloin Hotel Reviews

Frequently asked questions

What's it like in Tenderloin?
Tenderloin is a metropolitan neighbourhood known for its major shopping area and popular theatre scene. Make sure that you visit Great American Music Hall and Van Ness Avenue as part of your Tenderloin travel plans.
How many hotels should I expect to find in the Tenderloin area?
If you're searching for places to stay in San Francisco, Expedia has something to meet your needs with 21 Tenderloin hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Tenderloin, will I receive a refund?
Yes! Most hotel bookings are fully refundable if you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to get the top deals on offer in Tenderloin.
What can I see and do in this San Francisco neighbourhood?
Sights like Great American Music Hall and SOMA Pilipinas can be part of your cultural tour of Tenderloin. A visit to Van Ness Avenue is also worth the trip while you're discovering the neighbourhood. Don't miss favourite places to visit in the surrounding area, such as Oracle Park, Pier 39 and Chase Center. When you're sightseeing in San Francisco, Marrakech Magic Theater and Hotel Mark Twain are also worth a stop.