Upstate South Carolina Holidays

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Photo by Victoria S

Where to stay in Upstate South Carolina

Find the best Upstate South Carolina areas and neighborhoods for the activities you enjoy most. Learn more about Upstate South Carolina
Greenville which includes a bridge, a garden and autumn leaves

Greenville Downtown

2 out of top 10 points of interest in this area

The ample dining options and beautiful river views are top of the list for many visitors to Greenville Downtown. A stop by The Peace Center or Bon Secours Wellness Arena might round out your trip.

Find hotels in Greenville Downtown

Top hotels in Upstate South Carolina

Hyatt Regency Greenville
Hyatt Regency Greenville
3.5 out of 5
220 N Main St, Greenville, SC
Fully refundableReserve now, pay when you stay
The price is 3.320.923 ₫ per night from 3 Jul to 4 Jul
3.320.923 ₫
3.762.604 ₫ total
3 Jul - 4 Jul
includes taxes & fees
8.6/10 Excellent! (1,000 reviews)
"Always our preferred place for convenience and consistent amenities"

Reviewed on 22 Jun 2025

Hyatt Regency Greenville
La Quinta Inn & Suites by Wyndham Greenville Haywood
La Quinta Inn & Suites by Wyndham Greenville Haywood
3 out of 5
65 W Orchard Park Dr, Greenville, SC
Fully refundableReserve now, pay when you stay
The price is 1.820.564 ₫ per night from 1 Jul to 2 Jul
1.820.564 ₫
2.002.620 ₫ total
1 Jul - 2 Jul
includes taxes & fees
7.2/10 Good! (1,001 reviews)
"Still a fine value for money hotel, with all features being average plus at worst. One negative (other than forgetting soaps in the room) is that there were no grab bars by the toilet in the room, which proved to be a difficult experience for us."

Reviewed on 24 Jun 2025

La Quinta Inn & Suites by Wyndham Greenville Haywood
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
3.5 out of 5
851 Congaree Rd, Greenville, SC
Fully refundable
The price is 2.794.840 ₫ per night from 30 Jun to 1 Jul
2.794.840 ₫
3.074.324 ₫ total
30 Jun - 1 Jul
includes taxes & fees
8.4/10 Very Good! (1,003 reviews)
"Great"

Reviewed on 26 Jun 2025

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
See all 2,742 properties in Upstate South Carolina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Upstate South Carolina holiday package cost?
From as low as . Yes, you read that right. Our Upstate South Carolina holiday packages are the best way to stretch your budget. Bundle your preferred hotels, flights and rental car and get to know this top destination.
How do I get a cheap travel package to Upstate South Carolina?
Our Upstate South Carolina holiday packages mean plenty of savings for the savvy explorer. For the best deal, simply combine your hotel, flights and extras (such as activities) into one neat package. But great bargains are only the start of your next awesome adventure. Book with Expedia and you'll have more than 550 airlines and 1null000null000 hotels around the world to choose from. No matter your style, there's a package with your name on it.
Where should I stay in Upstate South Carolina?
Falls Park on the Reedy is one of the key things that draws people to Upstate South Carolina, so it makes perfect sense that many opt to stay in Greenville.
What are the top hotels in Upstate South Carolina?
When it comes to hotels in Greenville, Best Western Plus Greenville I-385 Inn & Suites and Comfort Inn Greenville - Haywood Mall are two terrific options. If you're heading to Seneca, Quality Inn Seneca US-123 and Tru by Hilton Seneca Clemson will make you feel at home.
How far in advance should I book my Upstate South Carolina holiday?
While prices fluctuate, we generally suggest booking your seats as soon as possible. Most international airfares are available on Expedia up to 12 months in advance. If circumstances have left you booking late, you might still be in luck. Cheap journeys to Upstate South Carolina occasionally appear just weeks before departure.
What does an Expedia Upstate South Carolina travel package include?
With Expedia, you can choose any combination of flights, hotels and car rentals to build your ideal Upstate South Carolina travel package. Once you've made your booking, you can add on the fun stuff like sightseeing tours and activities. Remember --- the more you bundle, the more dollars you'll save!
What should I know before booking a Upstate South Carolina travel package?
Design deals that suit your budget with an Expedia package. Hotels, flights, rental cars --- we're a one-stop shop for all of them. You'll save big bucks just by bundling your bookings. Whether you're embarking on an adventure in the snow or getting some sun on a warm beach, your dream getaway is just a few clicks away.
Can I choose my airline with a Upstate South Carolina Expedia holiday package?
Yes --- that's one of the best things about an Expedia holiday package. You can mix and match your flights, hotels and more. We have more than 550 airline partners throughout the world, so you have lots of choice when putting together your Upstate South Carolina getaway.
If I'm not able to travel, can I cancel my Upstate South Carolina holiday package?
Yes, you can cancel your Upstate South Carolina booking if your plans have changed. Whether you'll incur a fee or not depends on your hotel, airline or car rental company. It may be possible to change or cancel for free if you booked in the last 24 hours. Visit our Customer Service Portal to learn more.

Popular places to visit

Falls Park on the Reedy

Falls Park on the Reedy

Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the great live music or attend a sporting event in this family-friendly area.

Falls Park on the Reedy
Fred W. Symmes Chapel

Fred W. Symmes Chapel

You can find out about the history of Cleveland with a visit to Fred W. Symmes Chapel. Wander the lakeside and forests in this relaxing area.

Fred W. Symmes Chapel
Devils Fork State Park

Devils Fork State Park

You can take time to visit Devils Fork State Park during your travels to Salem. Wander the lakeside or discover the area's mountain views.

Devils Fork State Park