A red train on tracks, palm trees, and modern buildings.

Compare and book 4 Star hotels in Central San Diego, San Diego

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Central San Diego 4 Star Hotels

Our top choices for Central San Diego 4-star hotels

Restaurant

San Diego Marriott La Jolla

San Diego Marriott La Jolla
4.0 star property
University City
8.6 out of 10, Excellent, (2,405 reviews)
"Pretty below average hotel for the price"
United States
Jennifer
The price is 5.071.427 ₫
5.832.620 ₫ total
includes taxes & fees
14 Aug - 15 Aug
San Diego Marriott La Jolla
3 bars/lounges, lobby lounge, cocktail bar, cocktail bar

Lafayette Hotel & Club

Lafayette Hotel & Club
4.0 star property
University Heights
9.4 out of 10, Exceptional, (1,839 reviews)
"Great experience, staff was excellent food was delicious.. definitely recommend the hotel!"
United States
Lisa
The price is 7.578.720 ₫
8.711.318 ₫ total
includes taxes & fees
27 Jul - 28 Jul
Lafayette Hotel & Club
Room, 2 Queen Beds (Trendy, Firepit) | Lobby

Town and Country San Diego

Town and Country San Diego
4.0 star property
Mission Valley
8.6 out of 10, Excellent, (1,653 reviews)
"Great experience for a family trip!"
United States
Cynthia
The price is 4.719.595 ₫
6.333.070 ₫ total
includes taxes & fees
12 Aug - 13 Aug
Town and Country San Diego
Terrace/patio

DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley
4.0 star property
Mission Valley
8.4 out of 10, Very good, (1,746 reviews)
"I will definitely coming to stay there"
United States
Benedict
The price is 3.862.516 ₫
4.439.769 ₫ total
includes taxes & fees
9 Aug - 10 Aug
DoubleTree by Hilton Hotel San Diego - Mission Valley
Terrace/patio

Embassy Suites by Hilton San Diego La Jolla

Embassy Suites by Hilton San Diego La Jolla
4.0 star property
University City
8.8 out of 10, Excellent, (1,985 reviews)
"Room was good, breakfast was awesome along with evening drinks."
United States
Jagjit
The price is 5.122.215 ₫
6.637.444 ₫ total
includes taxes & fees
23 Aug - 24 Aug
Embassy Suites by Hilton San Diego La Jolla
Meeting facility

Hilton San Diego Mission Valley

Hilton San Diego Mission Valley
4.0 star property
Mission Valley
8.2 out of 10, Very good, (2,585 reviews)
"Great location, clean rooms"
United States
T'Andra
The price is 3.849.358 ₫
4.424.645 ₫ total
includes taxes & fees
5 Aug - 6 Aug
Hilton San Diego Mission Valley
Outdoor pool, pool loungers

Hyatt Regency La Jolla

Hyatt Regency La Jolla
4.0 star property
University City
9.0 out of 10, Wonderful, (1,002 reviews)
"Staff was very helpful."
United States
Yesenia
The price is 5.578.780 ₫
7.381.884 ₫ total
includes taxes & fees
16 Aug - 17 Aug
Hyatt Regency La Jolla
Lobby

Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
4.0 star property
Mission Valley
9.2 out of 10, Wonderful, (3,111 reviews)
"The hotel was nice & clean!"
United States
Vanesa Janet
The price is 4.947.220 ₫
5.686.672 ₫ total
includes taxes & fees
3 Aug - 4 Aug
Legacy Resort Hotel & Spa
Outdoor pool, open 6:00 AM to 10:00 PM, pool cabanas (surcharge)

San Diego Marriott Mission Valley

San Diego Marriott Mission Valley
4.0 star property
Mission Valley
8.8 out of 10, Excellent, (1,019 reviews)
"Our room was clean and cozy, the staff was so friendly and attentive, and the breakfast buffet was a convenient amenity."
United States
Olivia Joy
The price is 4.447.235 ₫
5.111.875 ₫ total
includes taxes & fees
23 Aug - 24 Aug
San Diego Marriott Mission Valley
Lobby

DoubleTree by Hilton San Diego - Hotel Circle

DoubleTree by Hilton San Diego - Hotel Circle
4.0 star property
Mission Valley
7.2 out of 10, Good, (1,895 reviews)
"I’ve stayed at this hotel a couple of times in the past and will choose this hotel more frequently in the future."
United States
Mario
The price is 3.646.733 ₫
4.191.738 ₫ total
includes taxes & fees
3 Aug - 4 Aug
DoubleTree by Hilton San Diego - Hotel Circle
Outdoor pool

Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel
4.0 star property
Mission Valley
8.6 out of 10, Excellent, (1,708 reviews)
"Great area and kids loved the pool"
United States
Robert
The price is 3.763.045 ₫
4.325.432 ₫ total
includes taxes & fees
23 Aug - 24 Aug
Sheraton Mission Valley San Diego Hotel
Deluxe 2 King Bedrooms, Multiple Beds, Sleeps 11ppl | Terrace/patio

City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.8 out of 10, Exceptional, (180 reviews)
"Enjoyed my stay! Clean spacious room and friendly staff."
United States
omokayode
The price is 3.746.467 ₫
5.118.794 ₫ total
includes taxes & fees
19 Aug - 20 Aug
City24 Hotel Little Italy Mission Hills
BBQ/picnic Area

Residence Inn by Marriott San Diego Mission Valley

Residence Inn by Marriott San Diego Mission Valley
4.5 star property
Mission Valley
8.8 out of 10, Excellent, (1,000 reviews)
"It was spacious and convenient but it was very dirty"
United States
Kabnne
Residence Inn by Marriott San Diego Mission Valley
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Learn more about Central San Diego

Explore the seaside area of Central San Diego—beaches, sports teams and popular sights like San Diego Zoo.

See all hotels in Central San Diego
A red train on tracks, palm trees, and modern buildings.

Top Central San Diego Hotel Reviews

Lafayette Hotel & Club

Lafayette Hotel & Club

10/10 Excellent
"Amazing easy and GORGEOUS"
Kristen 1-night trip
Posted 2 hours ago
Lafayette Hotel & Club
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

10/10 Excellent
"The room was excellent. I shared the room with friends. The layout in the bathroom however could have better utilized. Ample space for a double sink but only one sink. Combo shower and toilet meant you can to wait for the person in there to be finished. Bed were great. Loved the pool and hot tub. Staff were excellent at the front desk and the cleaning staff were simply exceptional. Teresa’s the restaurant was ok. Nothing special. Location was very convenient for us and loved the privacy and no noise."
Indar 2-night trip
Posted 2 hours ago
Legacy Resort Hotel & Spa

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Central San Diego?
Expedia can help you easily locate the ideal 4-star hotel for your holiday in Central San Diego. Use our filter tool to tailor your search by things like price, conveniences and hotel star rating and get access to terrific deals in a couple of clicks.

  • Search for the lowest price from 4.191.738 ₫

What's the difference between 5-star and 4-star hotels in Central San Diego?
Offering a welcoming guest experience and upscale surroundings, 4-star hotels are a wonderful option for your Central San Diego escape. These kinds of stays generally feature loads of handy amenities that make it easy to unpack and unwind — think complimentary bathrobes, restaurants and pools. Or live in the lap of luxury at a 5-star hotel designed to spoil you with high-end perks and amenities. A personalised service, complimentary toiletries and gourmet dining are typically featured at these plush retreats.
Does Central San Diego have any 4-star all-inclusive resorts?
Finding your dream resort in Central San Diego is as simple as entering your travel dates and selecting our "All inclusive" filter. Stay and play where everything is already taken care of like your accommodation, food, activities and entertainment, or choose a standard 4-star resort in or around this leading destination.