A red train on tracks, palm trees, and modern buildings.

Compare and book 4 Star hotels in Central San Diego, San Diego

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Check availability on Central San Diego 4 Star Hotels

Tonight
23 Oct - 24 Oct
Tomorrow
24 Oct - 25 Oct
This weekend
23 Oct - 25 Oct
Next weekend
30 Oct - 1 Nov

Our top choices for Central San Diego 4-star hotels

An outdoor patio with a stone fire pit, outdoor seating, string lights, and a tall, narrow heater.
A beach with clear skies, a rocky cliff, and a lighthouse in the distance.
A swimming pool with a visible water filtration system and a tiled edge.
A hotel room with a large bed, a chair, a nightstand, and a lamp.

1. Embassy Suites by Hilton San Diego La Jolla

Embassy Suites by Hilton San Diego La Jolla
University City
United States
Kunta
4.395.554 ₫
5.788.680 ₫ total
includes taxes & fees
31 Oct - 1 Nov
Embassy Suites by Hilton San Diego La Jolla
A bar area with a glass ceiling, a central bar counter, and multiple stools.
A large swimming pool with lounge chairs and umbrellas, surrounded by palm trees and a building with a striped facade.
A checkered floor with round tables and chairs, a patterned ceiling, and large windows.
A luxurious interior with a large chandelier, patterned sofas, and a view of a cityscape through a large window.

2. Lafayette Hotel & Club

Lafayette Hotel & Club
University Heights
United States
Stacey
7.054.593 ₫
8.108.906 ₫ total
includes taxes & fees
23 Nov - 24 Nov
Lafayette Hotel & Club
A spacious lobby with modern furniture, large windows, and a high ceiling with hanging lights.
A swimming pool with blue lounge chairs and umbrellas, surrounded by a building with balconies.
A pathway leading to a building labeled "LEGACY Hotel."
A hotel room with a large bed, a wooden nightstand, a bench, a desk with a TV, and a chair.

3. Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
Mission Valley
United States
christopher
4.187.052 ₫
4.813.042 ₫ total
includes taxes & fees
8 Nov - 9 Nov
Legacy Resort Hotel & Spa
An outdoor dining area with tables set for two, string lights overhead, and a view of a building in the background.
A spacious lobby with a modern staircase, comfortable seating, and large windows offering natural light.
An outdoor wedding venue with rows of chairs, floral centerpieces, and string lights.
A modern interior with a seating area featuring round tables and chairs, a large mirror, and a unique ceiling light fixture.

4. Hilton San Diego Mission Valley

Hilton San Diego Mission Valley
Mission Valley
Mexico
LUIS
3.369.801 ₫
3.873.418 ₫ total
includes taxes & fees
1 Nov - 2 Nov
Hilton San Diego Mission Valley
An outdoor lounge area with seating, a fire feature, and a pool in the background.
A hotel with a large pool surrounded by lounge chairs and umbrellas, palm trees, and a well-lit building facade.
A spacious lobby with a bar area, leather armchairs, and a reception desk.
A modern restaurant with multiple seating areas, including booths and tables. There are hanging lights and a variety of plants.

5. Town and Country San Diego

Town and Country San Diego
Mission Valley
United States
Nelly
4.116.471 ₫
5.623.450 ₫ total
includes taxes & fees
24 Nov - 25 Nov
Town and Country San Diego
An outdoor dining area with tables and chairs, a fire feature, and a bar area with a stone wall and shelves.
A spacious gym with various exercise equipment, large windows, and a wooden floor.
A spacious indoor lounge area with a central fire feature, multiple seating arrangements, and a bar area.
A swimming pool with lounge chairs and umbrellas, surrounded by trees and a tall building in the background.

6. San Diego Marriott La Jolla

San Diego Marriott La Jolla
University City
United States
Josh
4.783.319 ₫
5.501.781 ₫ total
includes taxes & fees
30 Oct - 31 Oct
San Diego Marriott La Jolla
A swimming pool with lounge chairs and a waterfall feature, surrounded by palm trees and a building with multiple balconies.
A modern hotel with a prominent tower, multiple floors, and a well-lit entrance.
A modern outdoor seating area with a wooden wall, a hanging chair, and a large potted plant.
A modern lobby with a round table and four chairs, a reception desk, and a large window.

7. San Diego Marriott Mission Valley

San Diego Marriott Mission Valley
Mission Valley
United States
Eva
4.367.129 ₫
5.019.796 ₫ total
includes taxes & fees
24 Nov - 25 Nov
San Diego Marriott Mission Valley
A spacious hotel lobby with a long reception desk, multiple seating areas, and large windows offering views of the outdoors.
A hotel room with two beds, a nightstand with a lamp, a framed picture on the wall, and a view through an open door.
A modern hotel with a flat roof, large windows, and a sign reading "DOLLYWOOD HOTEL".
A hotel room with two beds, a TV, a desk, and a chair.

8. DoubleTree by Hilton San Diego - Hotel Circle

DoubleTree by Hilton San Diego - Hotel Circle
Mission Valley
United States
Ramiro
3.157.253 ₫
3.629.104 ₫ total
includes taxes & fees
22 Nov - 23 Nov
DoubleTree by Hilton San Diego - Hotel Circle
An outdoor seating area with wicker chairs and a fire pit, surrounded by palm trees and string lights.
A modern dining area with a large table, chairs, and hanging plants.
A poolside area with a concrete pool, lounge chairs, and a wooden deck.
A grand lobby with a marble floor, a central table with floral arrangements, a staircase, and potted plants.

9. DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley
Mission Valley
United States
Jenelle
3.492.411 ₫
4.014.351 ₫ total
includes taxes & fees
22 Nov - 23 Nov
DoubleTree by Hilton Hotel San Diego - Mission Valley
An outdoor seating area with sofas, a fire pit, and tables covered with blue tablecloths.
A rooftop swimming pool with sun loungers and umbrellas, surrounded by a landscaped area with trees and a tennis court.
A bar area with a long counter, multiple bar stools, and a pool table.
A spacious library with high ceilings, bookshelves, and a central staircase.

10. Hyatt Regency La Jolla

Hyatt Regency La Jolla
University City
United States
lisa
5.478.292 ₫
7.249.434 ₫ total
includes taxes & fees
19 Nov - 20 Nov
Hyatt Regency La Jolla
A narrow, enclosed walkway with wooden railings and a metal grid barrier, leading to a building entrance.
An outdoor seating area with sofas and chairs, a wooden staircase, and potted plants.
A modern interior with concrete walls, wooden beams, and a central planter with plants.
A modern reception desk with a glass top, a large window offering a view, and a potted plant.

11. City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
Middletown
United States
Donavin
2.994.972 ₫
4.255.496 ₫ total
includes taxes & fees
2 Nov - 3 Nov
City24 Hotel Little Italy Mission Hills
An outdoor patio with tables and chairs, string lights, and umbrellas.
Property amenity
A hotel room with a large bed, a TV, a desk with a chair, and a view of the city through large windows.
A modern room with a glass dining table, two bar stools, a sofa, and a TV stand with decorative items.

12. Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel
Mission Valley
United States
Leanna
4.160.401 ₫
4.782.173 ₫ total
includes taxes & fees
28 Oct - 29 Oct
Sheraton Mission Valley San Diego Hotel
BBQ/picnic Area
Private kitchen
Room
Room

13. Residence Inn by Marriott San Diego Mission Valley

Residence Inn by Marriott San Diego Mission Valley
Mission Valley
United States
Kabnne
Residence Inn by Marriott San Diego Mission Valley
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Learn more about Central San Diego

Explore the seaside area of Central San Diego—beaches, sports teams and popular sights like San Diego Zoo.

See all hotels in Central San Diego
A historic cathedral with intricate architecture, a prominent bell tower, and a blue-domed structure.
Photo by Bilen Z

Top Central San Diego Hotel Reviews

Lafayette Hotel & Club

Lafayette Hotel & Club

8/10 Good
"The rooms are so unique and the attention to detail is fantastic."
Nicholas 2-night trip
Posted 9 hours ago
Lafayette Hotel & Club

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Central San Diego?
Expedia can help you easily locate the ideal 4-star hotel for your holiday in Central San Diego. Use our filter tool to tailor your search by things like price, conveniences and hotel star rating and get access to terrific deals in a couple of clicks.
  • Search for the lowest price from 3.629.104 ₫
What's the difference between 5-star and 4-star hotels in Central San Diego?
Offering a welcoming guest experience and upscale surroundings, 4-star hotels are a wonderful option for your Central San Diego escape. These kinds of stays generally feature loads of handy amenities that make it easy to unpack and unwind — think complimentary bathrobes, restaurants and pools. Or live in the lap of luxury at a 5-star hotel designed to spoil you with high-end perks and amenities. A personalised service, complimentary toiletries and gourmet dining are typically featured at these plush retreats.
Does Central San Diego have any 4-star all-inclusive resorts?
Finding your dream resort in Central San Diego is as simple as entering your travel dates and selecting our "All inclusive" filter. Stay and play where everything is already taken care of like your accommodation, food, activities and entertainment, or choose a standard 4-star resort in or around this leading destination.

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