Compare and book 4 Star hotels in Esquilino, Rome

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Check availability on Esquilino 4 Star Hotels

Tonight
5 Dec - 6 Dec
Tomorrow
6 Dec - 7 Dec
This weekend
5 Dec - 7 Dec
Next weekend
12 Dec - 14 Dec

Top Esquilino 4 Star Hotels

Front of property
Napoleon Hotel

Napoleon Hotel

4.0 star property
Rome City Centre
8.4 out of 10, Very good, (1000)
"Perfect location and great breakfast."
United States
Marcia
Napoleon Hotel
Rooftop terrace
Hotel Palladium Palace

Hotel Palladium Palace

4.0 star property
Rome City Centre
8.2 out of 10, Very good, (922)
"Practical hotel, clean, has all amenities that you need, very good breakfast, close to main station but very safe. Walkable distance to Monti area where very good restaurants present."
United States
Sirin
The price is 2.702.440 ₫
3.433.286 ₫ total
includes taxes & fees
10 Dec - 11 Dec
Hotel Palladium Palace
Daily cooked-to-order breakfast (EUR 10 per person)
Hotel Aphrodite

Hotel Aphrodite

4.0 star property
Rome City Centre
7.6 out of 10, Good, (1001)
"Very covenient loaction to train station."
Canada
Terri
Hotel Aphrodite
Double Room, Jetted Tub | Minibar, in-room safe, desk, soundproofing
Mercure Roma Centro St. John (Apertura 2026)

Mercure Roma Centro St. John (Apertura 2026)

4.0 star property
Rome Historic Centre
7.8 out of 10, Good, (209)
"Great location. Helpful staff and nice breakfast offered for a fee. Rooms were clean and very nice. "
United States
Sandra
The price is 2.863.350 ₫
3.610.287 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Mercure Roma Centro St. John (Apertura 2026)
Daily buffet breakfast (EUR 16 per person)
Best Western Hotel President

Best Western Hotel President

4.0 star property
Rome Historic Centre
8.6 out of 10, Excellent, (1001)
"Good location, slightly removed from tourist packs."
United States
Michael
The price is 3.628.930 ₫
4.452.486 ₫ total
includes taxes & fees
8 Dec - 9 Dec
Best Western Hotel President
Property entrance
Hotel Morgana

Hotel Morgana

4.0 star property
Rome City Centre
8.2 out of 10, Very good, (1000)
"Great place to stay in Rome. Close to restaurants and walkable to many tourist spots. Great staff and lovely rooms"
United States
Helen
The price is 3.469.031 ₫
4.276.536 ₫ total
includes taxes & fees
8 Dec - 9 Dec
Hotel Morgana
Garden
Hotel Emona Aquaeductus

Hotel Emona Aquaeductus

4.0 star property
Rome Historic Centre
9.0 out of 10, Wonderful, (40)
"Phenomenal, sweet staff and gorgeous hotel!"
Canada
Savannah
Hotel Emona Aquaeductus
Front of property
Hotel Ariston

Hotel Ariston

4.0 star property
Rome City Centre
8.0 out of 10, Very good, (721)
"Everything was great, hotel room was hot and it was difficult for staff to turn it down."
United States
Ramaprasad
The price is 3.855.378 ₫
4.701.518 ₫ total
includes taxes & fees
8 Dec - 9 Dec
Hotel Ariston
Balcony
Doria Palace Boutique Hotel

Doria Palace Boutique Hotel

4.0 star property
Rome City Centre
8.8 out of 10, Excellent, (79)
"Staff were very helpful. Property was clean and the bed was comfy. Would have been nice to have some water/milk in the room for tea/coffee. Area is convenient, 15/20 min walk from most attractions. Molino opposite was very good for breakfast/dinner. "
United Kingdom
Megan
Doria Palace Boutique Hotel
Romantic Suite, Terrace | Premium bedding, down duvets, minibar, in-room safe
Mecenate Palace

Mecenate Palace

4.0 star property
Rome City Centre
9.0 out of 10, Wonderful, (1004)
"We have been here twice. The staff is very friendly it’s close to everything and very clean "
Canada
Joseph
The price is 3.531.282 ₫
4.345.013 ₫ total
includes taxes & fees
8 Dec - 9 Dec
Mecenate Palace
Exterior
Relais Manzoni

Relais Manzoni

4.0 star property
Rome Historic Centre
8.2 out of 10, Very good, (215)
"I really liked the staff Francesca was so helpful and so nice. The madam that served breakfast was so gracious. They went out of their way to be kind. "
Canada
Rachelle
Relais Manzoni
Exterior
Champagne Palace Hotel

Champagne Palace Hotel

4.0 star property
Rome City Centre
6.0 out of 10, (1000)
"Staffs were friendly "
United States
sarah
The price is 2.518.847 ₫
3.231.334 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Champagne Palace Hotel
Terrace/patio
Hotel Latinum

Hotel Latinum

4.0 star property
Rome Historic Centre
8.8 out of 10, Excellent, (25)
"The staff at Hotel Latinum was friendly and very helpful. The rooms were clean and just the right amount of space."
United States
Simon
The price is 2.483.400 ₫
3.193.291 ₫ total
includes taxes & fees
8 Dec - 9 Dec
Hotel Latinum
Free daily buffet breakfast
Hotel Best Roma

Hotel Best Roma

4.0 star property
Rome Historic Centre
7.6 out of 10, Good, (455)
"Excelent hotel it’s near to the Metro that connects you to all the attractions. The food was really good "
United States
Emilia
Hotel Best Roma
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Esquilino.
NH Collection Roma Palazzo Cinquecento

NH Collection Roma Palazzo Cinquecento

Piazza Dei Cinquecento, 90 Rome RM
The price is 6.560.089 ₫ per night from 5 Jan to 6 Jan
6.560.089 ₫
7.830.234 ₫ total
5 Jan - 6 Jan 2026
includes taxes & fees
9/10 Wonderful! (1,001 reviews)
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Top Esquilino Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Esquilino?
Best Western Hotel President is among our travellers' favourite 4-star hotels around Esquilino. Concierge services and premium bedding are just two of its many conveniences. Another pick that gets rave reviews for its excellent guest experience is Hotel Best Roma. Book your break here and make use of concierge services and a rooftop terrace.
How much does it cost to stay in a 4-star hotel in Esquilino?
With Expedia's sort and search filters, scoring a top deal on a 4-star hotel in Esquilino just got simpler. Start by keying in your chosen travel dates and length of your getaway. Then sort the results by price and pick the option that best matches your style and budget.

  • Search for the lowest price from 7.830.234 ₫

What's the difference between 5-star and 4-star hotels in Esquilino?
If you choose to holiday at a 4-star hotel in Esquilino, you'll typically find lots of conveniences to ensure you're comfortable, such as a restaurant, gym and pool. You can look forward to high-quality service and upmarket accommodation. Pick a 5-star hotel and you'll get a few more bells and whistles — think on-site spas, 24-hour front desk and indulgent turndown services. You'll most likely get more amenities and exclusive services at a 5-star getaway, but both are terrific options for luxury travellers.

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