Compare and book 4 Star hotels in Mission District, San Francisco

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Check availability on Mission District 4 Star Hotels

Our top choices for Mission District 4-star hotels

Exterior
Hyatt Regency San Francisco

Hyatt Regency San Francisco

4.0 star property
Downtown San Francisco
9.2 out of 10, Wonderful, (1992)
"Great location and bar"
United States
michael
The price is 3.788.050 ₫
5.670.311 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Hyatt Regency San Francisco
Exterior
DoubleTree by Hilton Hotel Berkeley Marina

DoubleTree by Hilton Hotel Berkeley Marina

4.0 star property
Berkeley Marina
8.2 out of 10, Very good, (3917)
"Great place to stay!"
United States
Rafael
The price is 3.131.806 ₫
3.607.684 ₫ total
includes taxes & fees
19 Dec - 20 Dec
DoubleTree by Hilton Hotel Berkeley Marina
Lobby sitting area
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4.0 star property
Fisherman's Wharf
9.0 out of 10, Wonderful, (7194)
"Good location and great hotel to stay, the bed was very comfortable and the breakfast was good with lots of options! "
Canada
Veronica
The price is 3.229.174 ₫
4.887.020 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Hotel Riu Plaza Fisherman's Wharf
Front of property – evening/night
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4.0 star property
Downtown San Francisco
8.6 out of 10, Excellent, (2109)
"Great stay "
United States
Samantha
The price is 2.465.068 ₫
2.901.262 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hilton San Francisco Financial District
Terrace/patio
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

4.0 star property
Downtown San Francisco
8.8 out of 10, Excellent, (2791)
"Great stay and clean hotel"
United States
LeoAngelo
The price is 2.643.581 ₫
3.111.363 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Club Quarters Hotel in San Francisco
Courtyard
InterContinental Mark Hopkins by IHG

InterContinental Mark Hopkins by IHG

4.0 star property
Downtown San Francisco
9.0 out of 10, Wonderful, (1217)
"Great hotel! Very centrally located. "
United States
Kseniya
The price is 3.796.128 ₫
5.573.982 ₫ total
includes taxes & fees
24 Dec - 25 Dec
InterContinental Mark Hopkins by IHG
Exterior
Kimpton Alton Fisherman's Wharf by IHG

Kimpton Alton Fisherman's Wharf by IHG

4.5 star property
Fisherman's Wharf
9.2 out of 10, Wonderful, (1513)
"Great hotel with excellent service and a delicious restaurant. "
United States
Kerry
The price is 3.005.268 ₫
4.623.164 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Kimpton Alton Fisherman's Wharf by IHG
Lobby
Grand Hyatt at SFO

Grand Hyatt at SFO

4.0 star property
San Francisco
9.8 out of 10, Exceptional, (1463)
"Beautiful property, extremely helpful staff at check in! "
United States
Bonita
The price is 7.618.618 ₫
8.509.654 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Grand Hyatt at SFO
Reception
Oakland Marriott City Center

Oakland Marriott City Center

4.0 star property
Downtown Oakland
9.0 out of 10, Wonderful, (1005)
"Excellent stay! "
United States
Robert
The price is 2.927.070 ₫
3.409.905 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Oakland Marriott City Center
American cuisine
Hilton San Francisco Airport Bayfront

Hilton San Francisco Airport Bayfront

4.0 star property
Bayfront
8.6 out of 10, Excellent, (2721)
"Nice airport hotel…staff was great, breakfast was amazing "
United States
Lynne
The price is 2.464.320 ₫
2.801.810 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hilton San Francisco Airport Bayfront
Room, 1 King Bed (High Floor) | City view
citizenM San Francisco Union Square

citizenM San Francisco Union Square

4.0 star property
Union Square
9.4 out of 10, Exceptional, (1422)
"Great location."
United States
Todd
The price is 2.821.590 ₫
3.320.870 ₫ total
includes taxes & fees
24 Dec - 25 Dec
citizenM San Francisco Union Square
Restaurant
Grand Hyatt San Francisco

Grand Hyatt San Francisco

4.0 star property
Union Square
8.8 out of 10, Excellent, (1004)
"Great loved the tub and the shower "
United States
Samantha
The price is 3.532.508 ₫
5.398.708 ₫ total
includes taxes & fees
26 Dec - 27 Dec
Grand Hyatt San Francisco
Exterior
Hyatt Regency San Francisco Downtown SOMA

Hyatt Regency San Francisco Downtown SOMA

4.0 star property
Downtown San Francisco
9.4 out of 10, Exceptional, (1306)
"Overall wonderful experience "
United States
Mary
The price is 4.146.682 ₫
5.932.600 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Hyatt Regency San Francisco Downtown SOMA
Room (Private Apartment) | Egyptian cotton sheets, premium bedding, minibar, in-room safe
The Clift Royal Sonesta San Francisco

The Clift Royal Sonesta San Francisco

4.0 star property
Union Square
9.2 out of 10, Wonderful, (1362)
"The hotel room was clean and above all else, the staff was incredible... We will only stay at this hotel when we come into town!"
United States
Jennie
The price is 3.298.887 ₫
4.911.055 ₫ total
includes taxes & fees
26 Dec - 27 Dec
The Clift Royal Sonesta San Francisco
Lobby sitting area
The Marker Union Square San Francisco

The Marker Union Square San Francisco

4.0 star property
Union Square
9.0 out of 10, Wonderful, (1094)
"Very courteous staff, rooms & amenities clean, comfortable bed"
Australia
Inna
The price is 3.475.039 ₫
4.089.947 ₫ total
includes taxes & fees
15 Dec - 16 Dec
The Marker Union Square San Francisco
Exterior
LUMA Hotel San Francisco

LUMA Hotel San Francisco

4.0 star property
Downtown San Francisco
9.6 out of 10, Exceptional, (2369)
"Excellent location and room was spacious, clean and very comfortable bed. We will definitely stay here again! Great, friendly staff was an added bonus! "
United States
Linda
The price is 5.140.590 ₫
6.050.343 ₫ total
includes taxes & fees
22 Dec - 23 Dec
LUMA Hotel San Francisco
Exterior
The Westin San Francisco Airport

The Westin San Francisco Airport

4.0 star property
Millbrae
8.8 out of 10, Excellent, (2041)
"Room great, location and shuttle were excellent Enjoyed 2 restaurants and Starbucks on site. "
United States
Robert
The price is 2.931.982 ₫
4.143.474 ₫ total
includes taxes & fees
22 Dec - 23 Dec
The Westin San Francisco Airport
Lobby
Beacon Grand, A Union Square Hotel

Beacon Grand, A Union Square Hotel

4.0 star property
Union Square
9.2 out of 10, Wonderful, (1805)
"Amazing place"
Australia
David
The price is 4.153.275 ₫
5.974.377 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Beacon Grand, A Union Square Hotel
Games room
Hotel Zephyr San Francisco

Hotel Zephyr San Francisco

4.0 star property
Fisherman's Wharf
8.6 out of 10, Excellent, (2321)
"Excellent location."
United States
Rena
The price is 3.519.591 ₫
5.073.225 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
Hotel Zephyr San Francisco
Exterior
JW Marriott San Francisco Union Square

JW Marriott San Francisco Union Square

4.5 star property
Union Square
8.8 out of 10, Excellent, (1000)
"Great staff and amenities "
United States
Jonathan
The price is 4.459.132 ₫
6.350.112 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
JW Marriott San Francisco Union Square
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Mission District.
Fairmont San Francisco

Fairmont San Francisco

950 Mason Street Atop Nob Hill San Francisco CA
The price is 5.931.450 ₫ per night from 15 Dec to 16 Dec
5.931.450 ₫
8.066.871 ₫ total
15 Dec - 16 Dec
includes taxes & fees
9/10 Wonderful! (1,437 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Mission District Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Mission District?
BEI San Francisco, Trademark Collection by Wyndham is among our travellers' favourite 4-star hotels around Mission District. A terrace and premium bedding are a couple of its many amenities. Another option that gets rave reviews for its excellent guest experience is San Francisco Proper Hotel. Book your holiday here and make use of a rooftop terrace and proposal/romance packages.
How much does it cost to stay in a 4-star hotel in Mission District?
To book a 4-star hotel in Mission District that's within your budget, make use of Expedia's sort and search filters. Check out the availability during your getaway dates and use our pricing filter to set your maximum rate. You can also sort your results by the most affordable property first.

  • Search for the lowest price from 8.066.871 ₫

What's the difference between 5-star and 4-star hotels in Mission District?
If you choose to spend your holiday at a 4-star hotel in Mission District, you'll usually find plenty of conveniences to ensure you're relaxed, such as a pool, gym and restaurant. You can experience excellent service and upmarket surroundings. Opt for a 5-star hotel and you'll have access to a few extra bells and whistles — think around-the-clock concierge, on-site spas and nightly turndown services. You're likely to get extra amenities and premium services at a 5-star getaway, though both are terrific options for luxury travellers.

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