Compare and book 4 Star hotels in Texas Medical Center, Houston

    calendar shield illustration
    Change your mind
    Book hotels with free cancellation
    deals illustration
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check availability on Texas Medical Center 4 Star Hotels

Tonight
27 Jun - 28 Jun
Tomorrow
28 Jun - 29 Jun
This weekend
27 Jun - 29 Jun
Next weekend
4 Jul - 6 Jul

Top Texas Medical Center 4 Star Hotels

Club Quarters Hotel Downtown, Houston
Lobby

Club Quarters Hotel Downtown, Houston

4.0 star property
8.4 out of 10, Very good, (3469)
"Good for a quick overnight stay! "
The price is 2.664.240 ₫
3.117.161 ₫ total
includes taxes & fees
1 Jul - 2 Jul
Club Quarters Hotel Downtown, Houston
Hilton Houston Plaza/Medical Center
Sun deck

Hilton Houston Plaza/Medical Center

4.5 star property
8.4 out of 10, Very good, (1400)
"Great stay "
The price is 2.381.622 ₫
2.816.520 ₫ total
includes taxes & fees
2 Jul - 3 Jul
Hilton Houston Plaza/Medical Center
Magnolia Hotel Houston, A Tribute Portfolio Hotel
View from property

Magnolia Hotel Houston, A Tribute Portfolio Hotel

4.0 star property
9.0 out of 10, Wonderful, (1043)
"Will be staying here again if needing downtown area. "
The price is 3.082.160 ₫
3.687.100 ₫ total
includes taxes & fees
6 Jul - 7 Jul
Magnolia Hotel Houston, A Tribute Portfolio Hotel
The Whitehall Houston
City view from property

The Whitehall Houston

4.0 star property
8.4 out of 10, Very good, (1537)
"Great hotel and location "
The price is 3.138.318 ₫
3.671.833 ₫ total
includes taxes & fees
4 Jul - 5 Jul
The Whitehall Houston
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Exterior detail

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4.0 star property
8.2 out of 10, Very good, (2139)
"Great stay"
The price is 2.583.425 ₫
3.043.763 ₫ total
includes taxes & fees
27 Jul - 28 Jul
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
The Royal Sonesta Houston Galleria
Exterior

The Royal Sonesta Houston Galleria

4.0 star property
8.2 out of 10, Very good, (1082)
"This hotel is very clean and staff is extremely helpful and welcoming."
The price is 3.064.858 ₫
4.257.569 ₫ total
includes taxes & fees
7 Jul - 8 Jul
The Royal Sonesta Houston Galleria
Blossom Hotel Houston
City view

Blossom Hotel Houston

4.0 star property
9.2 out of 10, Wonderful, (3360)
"We really enjoyed our stay "
The price is 4.367.264 ₫
5.109.698 ₫ total
includes taxes & fees
27 Jul - 28 Jul
Blossom Hotel Houston
Hyatt Regency Houston/Galleria
Outdoor pool, open 6:00 AM to 10:00 PM, pool umbrellas, pool loungers

Hyatt Regency Houston/Galleria

4.0 star property
8.8 out of 10, Excellent, (1003)
"It was a beautiful stay "
The price is 3.421.720 ₫
4.033.712 ₫ total
includes taxes & fees
13 Jul - 14 Jul
Hyatt Regency Houston/Galleria
Hilton Americas-Houston
Exterior

Hilton Americas-Houston

4.0 star property
9.4 out of 10, Exceptional, (1336)
"The room area was very quiet and the buffet breakfast had a variety of food options."
The price is 4.158.304 ₫
4.926.337 ₫ total
includes taxes & fees
13 Jul - 14 Jul
Hilton Americas-Houston
The Laura Hotel, Houston Downtown, Autograph Collection
Egyptian cotton sheets, premium bedding, pillow-top beds, in-room safe

The Laura Hotel, Houston Downtown, Autograph Collection

4.5 star property
9.0 out of 10, Wonderful, (1002)
"Great stay!"
The price is 4.675.480 ₫
5.564.875 ₫ total
includes taxes & fees
3 Jul - 4 Jul
The Laura Hotel, Houston Downtown, Autograph Collection
Marriott Marquis Houston
2 outdoor pools, open 6:00 AM to 10:00 PM, pool cabanas (surcharge)

Marriott Marquis Houston

4.0 star property
8.8 out of 10, Excellent, (1007)
"Stayed here for dreamcon weekend will do so again !"
The price is 5.668.040 ₫
7.484.165 ₫ total
includes taxes & fees
13 Jul - 14 Jul
Marriott Marquis Houston
DoubleTree by Hilton Hotel Houston - Greenway Plaza
Business centre

DoubleTree by Hilton Hotel Houston - Greenway Plaza

4.0 star property
8.0 out of 10, Very good, (1009)
"Great location "
The price is 2.244.692 ₫
2.626.289 ₫ total
includes taxes & fees
6 Jul - 7 Jul
DoubleTree by Hilton Hotel Houston - Greenway Plaza
C. Baldwin, Curio Collection by Hilton
Outdoor banquet area

C. Baldwin, Curio Collection by Hilton

4.0 star property
8.6 out of 10, Excellent, (1004)
"Nice staff and beautiful property. "
The price is 3.833.894 ₫
5.177.848 ₫ total
includes taxes & fees
11 Jul - 12 Jul
C. Baldwin, Curio Collection by Hilton
The Chifley Houston, Tapestry Collection by Hilton
Lobby

The Chifley Houston, Tapestry Collection by Hilton

4.0 star property
9.2 out of 10, Wonderful, (1005)
"Great place to stay"
The price is 3.083.124 ₫
3.607.255 ₫ total
includes taxes & fees
6 Jul - 7 Jul
The Chifley Houston, Tapestry Collection by Hilton
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Lobby

DoubleTree by Hilton Houston Medical Center Hotel & Suites

4.0 star property
8.2 out of 10, Very good, (366)
"Good hotel and good location :-)"
The price is 3.009.024 ₫
3.520.558 ₫ total
includes taxes & fees
13 Jul - 14 Jul
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Hotel Zaza Houston Museum District
1 bedroom, premium bedding, pillow-top beds, minibar

Hotel Zaza Houston Museum District

4.5 star property
9.0 out of 10, Wonderful, (1697)
"The best stay at a hotel! "
Hotel Zaza Houston Museum District
Hyatt Regency Houston Downtown
City view

Hyatt Regency Houston Downtown

4.0 star property
9.4 out of 10, Exceptional, (1012)
"Great place to stay "
The price is 3.630.680 ₫
4.408.534 ₫ total
includes taxes & fees
5 Jul - 6 Jul
Hyatt Regency Houston Downtown
The Moran CITYCENTRE
Exterior

The Moran CITYCENTRE

4.0 star property
8.8 out of 10, Excellent, (1001)
"Beautiful hotel and great location "
The price is 4.678.092 ₫
6.251.561 ₫ total
includes taxes & fees
4 Jul - 5 Jul
The Moran CITYCENTRE
Omni Houston Hotel
Interior

Omni Houston Hotel

4.0 star property
9.0 out of 10, Wonderful, (1003)
"Would stay again ANY day!!"
The price is 4.348.196 ₫
5.163.702 ₫ total
includes taxes & fees
6 Jul - 7 Jul
Omni Houston Hotel
Houston Marriott Westchase
Exterior

Houston Marriott Westchase

4.0 star property
8.2 out of 10, Very good, (1004)
"Good place to stay and looks nice"
The price is 2.904.544 ₫
3.411.677 ₫ total
includes taxes & fees
18 Jul - 19 Jul
Houston Marriott Westchase
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Texas Medical Center.
The Post Oak Hotel at Uptown Houston

The Post Oak Hotel at Uptown Houston

1600 West Loop South, Houston, TX
The price is 14.195.680 ₫ per night from 13 Jul to 14 Jul
14.195.680 ₫
16.608.945 ₫ total
13 Jul - 14 Jul
includes taxes & fees
9.4/10 Exceptional! (759 reviews)
Still don't see what you're looking for?
See all properties in Texas Medical Center.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the best 4-star hotels in Texas Medical Centre?
Blossom Hotel Houston and DoubleTree by Hilton Houston Medical Centre Hotel & Suites are two highly recommended picks situated in or near Texas Medical Centre. Both have a 4-star rating and promise luxury comfort alongside an unbeatable traveller experience. Book a stay at the first and enjoy access to premium bedding and designer toiletries. The second has premium bedding and a swimming pool, among other amenities.
How much does it cost to stay in a 4-star hotel in Texas Medical Centre?
With Expedia's handy search filters, scoring a top deal on a 4-star hotel in Texas Medical Centre just got simpler. Start by entering your chosen travel dates and length of your stay. Then sort the results by price and pick the option that best matches your style and budget.

  • Search for the lowest price from 4.785.184 ₫

What's the difference between 5-star and 4-star hotels in Texas Medical Centre?
Offering a welcoming guest experience and upmarket décor, 4-star hotels are a fantastic option for your Texas Medical Centre getaway. These types of stays generally come with loads of handy amenities that make it easy to unpack and unwind --- think large beds, bathrobes, pools and restaurants. Or enjoy even more lavishness at a 5-star hotel designed to pamper with high-end perks and amenities. Full-service health clubs, complimentary toiletries and fine dining are typically featured at these swanky properties.