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The 10 Best 4 Star Hotels in Uptown - 2026 Updated Prices

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Our top choices for Uptown 4-star hotels

A spiral staircase with a black metal railing and a white wall.

1. 21c Museum Hotel Cincinnati

Downtown Cincinnati

Michael

4.815.694 ₫ total

includes taxes & fees

29 Nov - 30 Nov

A spacious lobby with a high ceiling, modern lighting fixtures, and a central staircase.

2. Hyatt Regency Cincinnati

Downtown Cincinnati

Christy

4.779.866 ₫ total

includes taxes & fees

5 Nov - 6 Nov

A grand hall with ornate chandeliers, a central staircase, and a seating area with patterned upholstery.

3. Hilton Cincinnati Netherland Plaza

Downtown Cincinnati

Margielyn Peladas

3.512.432 ₫ total

includes taxes & fees

22 Nov - 23 Nov

A city square with a fountain, surrounded by modern buildings including a Westin hotel.

4. The Westin Cincinnati

Downtown Cincinnati

Kevin

3.974.227 ₫ total

includes taxes & fees

22 Nov - 23 Nov

A lobby with a reception desk, a seating area with orange sofas, and a patterned carpet.

5. voco The Clair Cincinnati Downtown by IHG

Downtown Cincinnati

Wisty

3.992.258 ₫ total

includes taxes & fees

8 Nov - 9 Nov

A rooftop terrace with outdoor seating, overlooking a cityscape with historic buildings and a modern structure.

6. Hotel Covington Cincinnati Riverfront

Central Business District

Don

5.954.003 ₫ total

includes taxes & fees

23 Nov - 24 Nov

A modern living room with a fireplace, sofas, armchairs, and a coffee table.

7. The Summit Hotel

Cincinnati

Begum

4.964.896 ₫ total

includes taxes & fees

25 Nov - 26 Nov

A multi-story hotel with a brick facade, large windows, and a landscaped courtyard.

8. Graduate by Hilton Cincinnati

Corryville

Kelly

4.016.285 ₫ total

includes taxes & fees

9 Nov - 10 Nov

A spacious lobby with a modern design, featuring a seating area with sofas and chairs, a dining area with tables, and a kitchen in the background.

9. AC Hotel by Marriott Cincinnati at The Banks

Downtown Cincinnati

Maria

4.412.898 ₫ total

includes taxes & fees

23 Nov - 24 Nov

A spacious lobby with a stone fireplace, a chandelier, and a staircase leading to upper floors.

10. DoubleTree by Hilton Cincinnati Airport

Florence

Thomas Blake

4.660.856 ₫ total

includes taxes & fees

8 Nov - 9 Nov

A modern living room with dark sofas, a coffee table, and a chandelier. There are bookshelves with decorative items and a large window.

11. Renaissance Cincinnati Downtown Hotel

Downtown Cincinnati

John

5.514.075 ₫ total

includes taxes & fees

31 Oct - 1 Nov

A spacious lobby with leather armchairs, a reception desk, and a large potted plant.

12. DoubleTree Suites by Hilton Hotel Cincinnati - Blue Ash

Sharonville

TRACEY

2.573.254 ₫ total

includes taxes & fees

8 Nov - 9 Nov

A modern outdoor seating area with a fire feature, surrounded by black wicker chairs and teal cushions, overlooking a cityscape at sunset.

13. Hotel Celare, Cincinnati Midtown, a Tribute Portfolio Hotel

Cincinnati

Shelley

4.405.038 ₫ total

includes taxes & fees

29 Nov - 30 Nov

A cozy lounge area with wooden flooring, cushioned seating, and hanging pendant lights.

14. The Cincinnatian Hotel Curio Collection by Hilton

Downtown Cincinnati

Maria

4.508.495 ₫ total

includes taxes & fees

19 Nov - 20 Nov

A rooftop lounge with outdoor seating, a view of a stadium, and city buildings in the background.

15. Moxy Cincinnati Downtown

Downtown Cincinnati

Jeff

4.817.816 ₫ total

includes taxes & fees

29 Nov - 30 Nov

A spacious hotel lobby with a long corridor, comfortable seating areas, and large windows offering views of the outside.

16. Hilton Cincinnati Airport

Florence

Carol

3.446.935 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A modern hotel with a curved facade, large windows, and a well-lit entrance.

17. Doubletree By Hilton Lawrenceburg

Lawrenceburg

Christina

3.048.117 ₫ total

includes taxes & fees

30 Nov - 1 Dec

A modern building with a large glass facade, the name "KINLEY" prominently displayed above the entrance.

18. Kinley Cincinnati Downtown, a Tribute Portfolio Hotel

Downtown Cincinnati

Richard

4.779.869 ₫ total

includes taxes & fees

27 Nov - 28 Nov

An outdoor patio with round tables, chairs, and a central fire pit.

19. TownePlace Suites by Marriott Cincinnati Mason

Mason

Elvin

3.366.703 ₫ total

includes taxes & fees

19 Nov - 20 Nov

A spacious living area with a wooden staircase, a dining table with chairs, a kitchen with modern appliances, and a large TV.

20. Baldwin Flats

Licking Riverside

Dan

3.945.698 ₫ total

includes taxes & fees

3 Nov - 4 Nov

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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Uptown.

The Lytle Park Hotel, Autograph Collection

311 PIKE ST Cincinnati OH

7.645.598 ₫

9.121.197 ₫ total

22 Nov - 23 Nov

includes taxes & fees

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Pool Spa Hot tub Breakfast included Waterpark

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Uptown

Restaurants, a zoo and sights from Cincinnati Zoo and Botanical Garden to Fifth Third Arena—discover it all in Uptown.

See all hotels in Uptown

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Top Uptown Hotel Reviews

Hotel Covington Cincinnati Riverfront

10/10 Excellent

"The room was clean. The staff was friendly and helpful. We had dinner at the onsite restaurant, our meal was delicious."

Renaissance Cincinnati Downtown Hotel

8/10 Good

"Nice hotel in a central location. Parking (valet) is $50/day with in and out privileges. On the day I left, instead of pulling into one of the spaces open at the curb, the valet opted instead to throw on my car’s hazards in the middle of 4th Street, backing up traffic. He also failed to put my car into park before he got out so it started drifting away. When people on the sidewalk (including me) started yelling, he jumped back in and managed to put it in park, still blocking the street but at least it didn’t crash. I loaded the back and drove off. Although I’m guessing the valet is an independent contractor and not a hotel employee, I’m deducting a star for the experience. Absolutely wild - but glad nobody was hurt. The hotel itself is fine."

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Uptown?

With Expedia's sort and search filters, locking in a terrific deal on a 4-star hotel in Uptown just got easier. Start by entering your chosen travel dates and length of your holiday. Then sort the results by price and choose a hotel that best suits your budget and style.

Search for the lowest price from 9.121.197 ₫

What's the difference between 5-star and 4-star hotels in Uptown?

Offering a welcoming guest experience and upscale décor, 4-star hotels are a fabulous option for your Uptown escape. These types of accommodation generally feature loads of handy amenities that make it easy to unpack and recharge — think complimentary bathrobes, gyms and restaurants. Or live in the lap of luxury at a 5-star hotel designed to indulge you in exclusive perks and amenities. A personalised service, oversized bathrooms and gourmet dining are typically featured at these swanky properties.

Does Uptown have any 4-star all-inclusive resorts?

Use our "All inclusive" filter to search for your next dream getaway in Uptown where just about everything is taken care of, from your meals to your accommodation, activities and entertainment. We can also help you find standard 4-star stays in and around this sought-after destination.

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Treat yourself

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Check availability on Uptown 4 Star Hotels

Our top choices for Uptown 4-star hotels

1. 21c Museum Hotel Cincinnati

2. Hyatt Regency Cincinnati

3. Hilton Cincinnati Netherland Plaza

4. The Westin Cincinnati

5. voco The Clair Cincinnati Downtown by IHG

6. Hotel Covington Cincinnati Riverfront

7. The Summit Hotel

8. Graduate by Hilton Cincinnati

9. AC Hotel by Marriott Cincinnati at The Banks

10. DoubleTree by Hilton Cincinnati Airport

11. Renaissance Cincinnati Downtown Hotel

12. DoubleTree Suites by Hilton Hotel Cincinnati - Blue Ash

13. Hotel Celare, Cincinnati Midtown, a Tribute Portfolio Hotel

14. The Cincinnatian Hotel Curio Collection by Hilton

15. Moxy Cincinnati Downtown

16. Hilton Cincinnati Airport

17. Doubletree By Hilton Lawrenceburg

18. Kinley Cincinnati Downtown, a Tribute Portfolio Hotel

19. TownePlace Suites by Marriott Cincinnati Mason

20. Baldwin Flats

Explore similar 5-star hotels

The Lytle Park Hotel, Autograph Collection

Learn more about Uptown

Top Uptown Hotel Reviews

Hotel Covington Cincinnati Riverfront

Renaissance Cincinnati Downtown Hotel

Frequently asked questions

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