Compare and book 5 Star hotels in Antwerp, Flemish Region

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Our top choices for Antwerp 5-star hotels

Indoor pool, open 7:00 AM to 10:00 PM, pool loungers
Botanic Sanctuary Antwerp - The Leading Hotels of the World

Botanic Sanctuary Antwerp - The Leading Hotels of the World

Botanic Sanctuary Antwerp - The Leading Hotels of the World
5.0 star property
Old Town
9.6 out of 10, Exceptional, (111)
"Beautiful property and amazing welcoming staff!"
United States
Joe
The price is 12.086.664 ₫
13.090.275 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Botanic Sanctuary Antwerp - The Leading Hotels of the World
Property amenity
Sapphire House Antwerp, Autograph Collection

Sapphire House Antwerp, Autograph Collection

Sapphire House Antwerp, Autograph Collection
5.0 star property
Old Town
9.2 out of 10, Wonderful, (223)
"Nice hotel in a very good location and great room design. I booked at Expedia for 400 EUR and the hotel billed Expedia 333 EUR. "
United Kingdom
Michael
The price is 4.881.161 ₫
5.357.856 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Sapphire House Antwerp, Autograph Collection
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Antwerp.
Hotel Jamingo

Hotel Jamingo

53 Frankrijklei Antwerp Vlaams Gewest
The price is 3.441.926 ₫ per night from 10 Jan to 11 Jan
3.441.926 ₫
4.420.161 ₫ total
10 Jan - 11 Jan 2026
includes taxes & fees
9/10 Wonderful! (307 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Antwerp and related destinations

Diamonds sparkle in the world-famous district while Gothic architecture frames the medieval heart of this port city. Climb the Cathedral of Our Lady's tower for panoramic views, then sample Belgian chocolate and waffles at the bustling Grote Markt.

See all hotels in Antwerp
Cathedral of Our Lady featuring a city, a church or cathedral and heritage architecture

Top Antwerp Hotel Reviews

Frequently asked questions

What are the best 5-star hotels in Antwerp?
Step into a world of indulgence at Sapphire House Antwerp, Autograph Collection. This is one of the most popular 5-star hotels in Antwerp based on Expedia guest reviews. From its prime location to its amenities and guest services, you can expect the highest standard of excellence.
How much does it cost to stay in a 5-star hotel in Antwerp?
The amount you pay for a 5-star hotel in Antwerp can vary based on when you want to travel and how long you plan to be away, among a range of factors. Use our price per night filter and other search tools to score the best deal on a high-end stay.

  • Search for the lowest price per night from 2.691.815 ₫

What makes a hotel 5 stars in Antwerp?
Faultless guest service characterises every 5-star hotel in Antwerp. From the instant you arrive, staff are at your beck and call, whether recommending activities and tours or providing in-room massage treatments. Also, hotels must offer upscale conveniences to be considered for a 5-star rating. These can include luxury bathrooms, on-site spa facilities, pools, gourmet kitchens and knowledgeable concierge.