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Compare and book 5 Star hotels in La Reina, Santiago

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Top La Reina 5 Star Hotels

NH Collection Plaza Santiago

5.0 star property
Providencia
8.8 out of 10, Excellent, (1004)
"Great location, in front of Costanera Center, and within walking distance from many restaurants. "
United States
HUBERTH
The price is 2.776.762 ₫
2.776.762 ₫ total
21 Dec - 22 Dec
NH Collection Plaza Santiago

Mandarin Oriental, Santiago

5.0 star property
Las Condes
9.2 out of 10, Wonderful, (928)
"Excellent service ; beatiful and great hotel ! "
United States
Lizzette Yolanda
The price is 8.041.325 ₫
8.041.325 ₫ total
13 Dec - 14 Dec
Mandarin Oriental, Santiago

W Santiago

5.0 star property
Las Condes
8.8 out of 10, Excellent, (513)
"Excellent hotel"
United States
Domenico
The price is 6.924.767 ₫
6.924.767 ₫ total
23 Dec - 24 Dec
W Santiago

The Ritz-Carlton, Santiago

5.0 star property
Las Condes
9.4 out of 10, Exceptional, (589)
"The staff was fantastic!"
United States
Kerry
The price is 8.410.435 ₫
8.410.435 ₫ total
12 Dec - 13 Dec
The Ritz-Carlton, Santiago

Noi Vitacura

5.0 star property
Vitacura
8.6 out of 10, Excellent, (544)
"Excellent location and staff!"
United States
Kelvin
The price is 4.244.765 ₫
4.244.765 ₫ total
1 Jan - 2 Jan 2026
Noi Vitacura

The Singular Santiago

5.0 star property
Downtown Santiago
9.6 out of 10, Exceptional, (671)
"First and foremost the staff are very welcoming and most helpful. They are at the heart of the hotels wonderful ambiance. The property has a prime location next to a beautiful park and a lively neighborhood full with great restaurants. It’s within walking distance to museums, plaza de armas, the presidential palace among others. We highly recommend this hotel. "
United States
Mona
The price is 6.195.775 ₫
6.195.775 ₫ total
24 Dec - 25 Dec
The Singular Santiago

Pullman Santiago Vitacura

5.0 star property
Vitacura
9.0 out of 10, Wonderful, (907)
"Clean and quiet"
United States
Nathan
The price is 1.582.140 ₫
1.582.140 ₫ total
31 Dec - 1 Jan 2026
Pullman Santiago Vitacura

LUUM by Norus

2.5 star property
Las Condes
LUUM by Norus
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Frequently asked questions

What are the best 5-star hotels in La Reina?
Gear up for 5-star luxuriousness at The Ritz-Carlton, Santiago, Mandarin Oriental, Santiago or W Santiago. These are some of the most popular retreats in La Reina based on Expedia customer reviews. Choose one and enjoy a taste of the high life!
How much does it cost to stay in a 5-star hotel in La Reina?
How much you pay for a 5-star hotel in La Reina can vary according to when you want to travel and how long you plan to be away, among a range of factors. Take advantage of our price per night filter and other search tools to score the best rate on a high-end getaway.

  • Search for the lowest price per night from 1.697.906 ₫

What makes a hotel 5 stars in La Reina?
Exemplary guest service is the defining feature of every 5-star hotel in La Reina. From the minute you step through the door, staff ensure your every need is met, whether recommending activities or providing in-room massage treatments. In addition, hotels must offer top-rate amenities to be eligible for a 5-star rating. These can include luxury bath products, spas or saunas, pools, fine dining restaurants and knowledgeable concierge.