Compare and book 5 Star hotels in Prague 10, Prague
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Prague 10 5 Star Hotels
Top Prague 10 5 Star Hotels
Michelangelo Grand Hotel Prague
Prague City Center
9.4 out of 10, Exceptional, (3108)
"Great location, lovely hotel "
Sally Louise
Almanac X Alcron Prague
Prague City Center
9.6 out of 10, Exceptional, (826)
"Beautiful hotel. Amazing staff and lovely room. Really well placed for the city. "
Louise
The price is 5.020.603 ₫
5.745.900 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton Prague
Karlín
8.4 out of 10, Very good, (1005)
"Very excellent Hotel would recommend to anyone!"
Damien
The price is 2.010.988 ₫
2.377.538 ₫ total
includes taxes & fees
7 Jan - 8 Jan 2026
Grandior Hotel Prague
Prague City Center
9.2 out of 10, Wonderful, (1204)
"Fabulous place to stay and within easy walking distance to shops and places of interest. "
Mairi
The price is 2.603.458 ₫
3.042.688 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
Grandium Hotel Prague
Prague City Center
9.2 out of 10, Wonderful, (1120)
"Great rooms, friendly staff, wonderful breakfast"
Toni
The price is 3.014.449 ₫
3.503.096 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Four Seasons Hotel Prague
Prague City Center
9.6 out of 10, Exceptional, (612)
"All perfect"
Amos
The price is 17.802.468 ₫
20.061.540 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
ANDAZ PRAGUE, BY HYATT
Prague City Center
9.6 out of 10, Exceptional, (172)
"Overall a great experience."
Mark
The price is 7.182.375 ₫
8.171.026 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Radisson Blu Hotel, Prague
Nové Město
9.0 out of 10, Wonderful, (500)
"Excellent services, well trained staff."
TETIANA
The price is 3.314.118 ₫
3.838.669 ₫ total
includes taxes & fees
7 Jan - 8 Jan 2026
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Prague 10.
K+K Hotel Central Prague
Hybernska 10 Prague
The price is 3.132.423 ₫ per night from 6 Jan to 7 Jan
3.132.423 ₫
3.635.387 ₫ total
6 Jan - 7 Jan 2026
includes taxes & fees
9.2/10 Wonderful! (1,032 reviews)
Still don't see what you're looking for?
See all properties in Prague 10.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Prague 10 Hotel Reviews
Explore a world of travel with Expedia
Hotels in Prague 10 by Star Rating
Accommodation near Prague 10 attractions
- Hotels near Fortuna Arena
- Hotels near Vinohrady Water Tower
- Hotels near Prague Castle
- Hotels near Prague Astronomical Clock
- Hotels near Charles Bridge
- Hotels near Wenceslas Square
- Hotels near Prague Zoo
- Hotels near Prague Congress Centre
- Hotels near St. Vitus Cathedral
- Hotels near Republic Square
- Hotels near Lesser Town Square
- Hotels near Prague Market
- Hotels near Powder Tower
Choose Your Prague 10 Hotel Style
- Business Hotels in Prague 10
- Family-Friendly Hotels in Prague 10
- Golf Hotels in Prague 10
- Historic Hotels in Prague 10
- Hotels Suites in Prague 10
- Hotels near Museums in Prague 10
- Hotels with Airport Transfers in Prague 10
- Hotels with Babysitting Services in Prague 10
- Hotels with Balcony in Prague 10
- Hotels with Breakfast in Prague 10
- Hotels with Connecting Rooms in Prague 10
- Hotels with Laundry Service in Prague 10
- Hotels with Parking in Prague 10
- Hotels with Restaurant in Prague 10
- Hotels with Room Service in Prague 10
- Hotels with a View in Prague 10
- Hotels with smoking rooms in Prague 10
- Pet-Friendly Hotels in Prague 10
- Romantic Hotels in Prague 10
- Shopping Hotels in Prague 10
- Spa Hotels in Prague 10
- Sports Hotels in Prague 10
- Winery Hotels in Prague 10
Explore more hotels
Expedia's Latest Trends
General