Photo by Lifang Yu

Compare and book 5 Star hotels in San Mateo, San Francisco

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on San Mateo 5 Star Hotels

Our top choices for San Mateo 5-star hotels

Terrace/patio
Fairmont San Francisco

Fairmont San Francisco

Fairmont San Francisco
5.0 star property
Downtown San Francisco
9.0 out of 10, Wonderful, (1429)
"Beautiful hotel "
United States
Xandy
The price is 5.933.250 ₫
8.069.318 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Fairmont San Francisco
View from property
Palace Hotel, a Luxury Collection Hotel, San Francisco

Palace Hotel, a Luxury Collection Hotel, San Francisco

Palace Hotel, a Luxury Collection Hotel, San Francisco
5.0 star property
Downtown San Francisco
9.2 out of 10, Wonderful, (1000)
"Everything was fantastic including the breakfast!"
United States
David
The price is 7.094.014 ₫
8.349.300 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Palace Hotel, a Luxury Collection Hotel, San Francisco
City view
Taj Campton Place

Taj Campton Place

Taj Campton Place
5.0 star property
Union Square
9.2 out of 10, Wonderful, (1001)
"Wonderful Staff and hospitality."
United States
Rachel
The price is 4.692.436 ₫
6.433.119 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Taj Campton Place
Terrace/patio
Four Seasons Hotel San Francisco

Four Seasons Hotel San Francisco

Four Seasons Hotel San Francisco
5.0 star property
Downtown San Francisco
9.4 out of 10, Exceptional, (1002)
"great room and staff. "
United States
chunguang
The price is 8.306.550 ₫
9.776.394 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
Four Seasons Hotel San Francisco
2 restaurants, breakfast, lunch, dinner served; Californian cuisine
The Ritz-Carlton, San Francisco

The Ritz-Carlton, San Francisco

The Ritz-Carlton, San Francisco
5.0 star property
Downtown San Francisco
9.4 out of 10, Exceptional, (1000)
"Excellent "
United States
Maximus
The price is 8.682.323 ₫
11.493.861 ₫ total
includes taxes & fees
29 Dec - 30 Dec
The Ritz-Carlton, San Francisco
Cocktail bar, pool views, open daily
Shashi Hotel Mountain View Palo Alto

Shashi Hotel Mountain View Palo Alto

Shashi Hotel Mountain View Palo Alto
5.0 star property
Mountain View
9.4 out of 10, Exceptional, (1175)
"Perfect place to stay and enjoy "
United States
Ali
The price is 3.348.990 ₫
3.690.482 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Shashi Hotel Mountain View Palo Alto
Breakfast, lunch, dinner served; al fresco dining
1 Hotel San Francisco

1 Hotel San Francisco

1 Hotel San Francisco
5.0 star property
Downtown San Francisco
9.2 out of 10, Wonderful, (483)
"The staff was incredible and we loved all of the design touches in the room. The attention to detail was impressive. "
United States
Eric
The price is 9.466.883 ₫
12.631.688 ₫ total
includes taxes & fees
22 Dec - 23 Dec
1 Hotel San Francisco
Rooftop terrace
Four Seasons Hotel San Francisco at Embarcadero

Four Seasons Hotel San Francisco at Embarcadero

Four Seasons Hotel San Francisco at Embarcadero
5.0 star property
Downtown San Francisco
9.6 out of 10, Exceptional, (1003)
"The views are jaw dropping. The service is excellent in all areas, particularly broom service. Very easy to park and car service to local locations. "
United States
stephanie
The price is 11.075.400 ₫
13.035.193 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Four Seasons Hotel San Francisco at Embarcadero
Suite, 1 Bedroom, Corner | Frette Italian sheets, premium bedding, down duvets, pillow-top beds
The St. Regis San Francisco

The St. Regis San Francisco

The St. Regis San Francisco
5.0 star property
Downtown San Francisco
9.4 out of 10, Exceptional, (692)
"Had a great stay "
United Kingdom
Thomas
The price is 9.519.570 ₫
12.405.463 ₫ total
includes taxes & fees
13 Dec - 14 Dec
The St. Regis San Francisco
View from property
The Ritz-Carlton, Half Moon Bay

The Ritz-Carlton, Half Moon Bay

The Ritz-Carlton, Half Moon Bay
5.0 star property
Half Moon Bay
9.0 out of 10, Wonderful, (647)
"The staff throughout the resort were extremely friendly and helpful."
United States
Steve
The price is 20.278.530 ₫
25.714.311 ₫ total
includes taxes & fees
15 Dec - 16 Dec
The Ritz-Carlton, Half Moon Bay
Outdoor pool
Four Seasons Hotel Silicon Valley at East Palo Alto

Four Seasons Hotel Silicon Valley at East Palo Alto

Four Seasons Hotel Silicon Valley at East Palo Alto
5.0 star property
East Palo Alto
9.4 out of 10, Exceptional, (666)
"Wonderful stay "
United States
Cindy
The price is 9.490.320 ₫
10.790.019 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Four Seasons Hotel Silicon Valley at East Palo Alto
Outdoor pool
Rosewood Sand Hill

Rosewood Sand Hill

Rosewood Sand Hill
5.0 star property
Menlo Park
9.4 out of 10, Exceptional, (274)
"Really great hotel and my go to place for anything in Palo Alto "
United States
Lisa
The price is 21.946.365 ₫
27.355.847 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Rosewood Sand Hill
Dining room
Treehouse Hotel Silicon Valley

Treehouse Hotel Silicon Valley

Treehouse Hotel Silicon Valley
5.0 star property
Sunnyvale
9.6 out of 10, Exceptional, (69)
"Great stay"
United States
Noah
The price is 7.556.667 ₫
9.110.186 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Treehouse Hotel Silicon Valley
Meeting facility
Nobu Hotel Palo Alto

Nobu Hotel Palo Alto

Nobu Hotel Palo Alto
5.0 star property
University South
9.2 out of 10, Wonderful, (434)
"Beautiful hotel. "
United States
Dianne
The price is 10.412.990 ₫
12.047.309 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Nobu Hotel Palo Alto
Property entrance
Hotel Drisco

Hotel Drisco

Hotel Drisco
5.0 star property
Pacific Heights
9.8 out of 10, Exceptional, (454)
"The breakfast was amazing, lots of variety including hot items cooked freshly"
United Kingdom
Julie Ann
The price is 14.211.754 ₫
16.530.047 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Hotel Drisco
Exterior
Clement Palo Alto – All-Inclusive Urban Resort

Clement Palo Alto – All-Inclusive Urban Resort

Clement Palo Alto – All-Inclusive Urban Resort
5.0 star property
Palo Alto
10.0 out of 10, Exceptional, (112)
"Great hotel!!"
United States
Matthew
The price is 14.690.727 ₫
18.024.603 ₫ total
includes taxes & fees
12 Dec - 13 Dec
Clement Palo Alto – All-Inclusive Urban Resort
Exterior
Fairmont Heritage Place, Ghirardelli Square

Fairmont Heritage Place, Ghirardelli Square

Fairmont Heritage Place, Ghirardelli Square
5.0 star property
Fisherman's Wharf
9.4 out of 10, Exceptional, (386)
"Great staff, clean, excellent location, spacious rooms"
United States
Christopher
The price is 21.333.330 ₫
25.066.663 ₫ total
includes taxes & fees
7 Jan - 8 Jan 2026
Fairmont Heritage Place, Ghirardelli Square
Front of property – evening/night
Neighbourgood Sutter Mansion

Neighbourgood Sutter Mansion

Neighbourgood Sutter Mansion
5.0 star property
Western Addition
9.4 out of 10, Exceptional, (226)
"The Sutter Mansion is gorgeous, historic and filled with original artwork. The bed was very comfortable. We had a few issues which were quickly rectified. Service is extraordinary."
United States
Jananne
The price is 7.537.920 ₫
8.782.242 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Neighbourgood Sutter Mansion
Terrace/patio
Dimond Abode Vacation Rental 3428

Dimond Abode Vacation Rental 3428

Dimond Abode Vacation Rental 3428
5.0 star property
Dimond
9.4 out of 10, Exceptional, (6)
"Great place, great customer service!"
United States
Anonymous traveller
Dimond Abode Vacation Rental 3428
Deluxe House | Balcony
Dimond Abode Vacation Rental

Dimond Abode Vacation Rental

Dimond Abode Vacation Rental
5.0 star property
Dimond
10.0 out of 10, Exceptional, (1)
"The unit was extremely clean and having access to a garage was definitely a plus for our stay! Nice touches, especially coffee / tea , snacks, and a well equipped kitchen made us feel welcomed the minute we stepped through the door. A+"
United States
Camille
Dimond Abode Vacation Rental
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in San Mateo.
Hyatt Regency San Francisco

Hyatt Regency San Francisco

5 Embarcadero Center San Francisco CA
The price is 3.788.050 ₫ per night from 14 Dec to 15 Dec
3.788.050 ₫
5.670.311 ₫ total
14 Dec - 15 Dec
includes taxes & fees
9.2/10 Wonderful! (1,987 reviews)
Still don't see what you're looking for?
See all properties in San Mateo.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about San Mateo

Nestled between San Francisco and Silicon Valley, this vibrant city offers Japanese gardens and hiking trails in Coyote Point Park. Families love the interactive CuriOdyssey science museum, while shoppers flock to Hillsdale Shopping Centre for retail therapy after farmers market visits.

See all hotels in San Mateo
San Mateo
Photo by Lifang Yu
Open Photo by Lifang Yu

Top San Mateo Hotel Reviews

Frequently asked questions

How much does it cost to stay in a 5-star hotel in San Mateo?
You can find many different pricing options for 5-star hotels in San Mateo on Expedia. The amount you pay will depend on your holiday dates, length of your trip and other factors. Compare all of the available accommodation for your preferred dates and make use of our pricing and other filters to lock in the ideal luxury stay.

  • Search for the lowest price per night from 2.901.262 ₫

What makes a hotel 5 stars in San Mateo?
From high-end dining venues and 24/7 fitness centres to swimming pools and luxury bedding, the 5-star experience in San Mateo is all about luxury and relaxation. But it requires more than just top-notch perks to receive a 5-star rating. Accommodation also have to offer outstanding guest-centric services like massage treatments, on-site dry cleaning and laundry and room service any time night or day.
Are there any 5-star all-inclusive resorts in San Mateo?
Find a luxury escape that includes your lodging, meals, drinks and entertainment in San Mateo with the help of our filters. Search for properties with a 5-star rating and click on the "All inclusive" filter. Double-check what's included in the price. That way, you'll be ready to maximise all the premium perks as soon as you arrive.

Explore a world of travel with Expedia