Compare and book 5 Star hotels in St. Louis, Missouri

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on St. Louis 5 Star Hotels

Top St. Louis 5 Star Hotels

The Ritz-Carlton, St. Louis

5.0 star property
9.2 out of 10, Wonderful, (541)
"Wish they still had a pool"
The price is 14.135.275 ₫
16.466.153 ₫ total
includes taxes & fees
11 Sept - 12 Sept
The Ritz-Carlton, St. Louis

Four Seasons Hotel St Louis

5.0 star property
9.4 out of 10, Exceptional, (1000)
"We’ve stayed at this hotel several times and keep coming back. Great hotel staff and property. "
The price is 11.143.925 ₫
13.030.480 ₫ total
includes taxes & fees
20 Aug - 21 Aug
Four Seasons Hotel St Louis
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in St. Louis.
Still don't see what you're looking for?
See all properties in St. Louis.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

St. Louis and related destinations

The Gateway Arch towers 630 feet above the Mississippi, with a tram that takes you to spectacular views at the top. Explore Forest Park's free museums, catch a Cardinals game at Busch Stadium, and don't miss Ted Drewes' frozen custard that locals swear by.

Top St. Louis Hotel Reviews

Frequently asked questions

What are the best 5-star hotels in St. Louis?
Treat yourself to a luxurious stay at Four Seasons Hotel St Louis. This is among the top 5-star hotels in St. Louis based on Expedia customer reviews. From its guest services to its well-appointed rooms and prime location, you can rely on the highest standard of excellence.
How much does it cost to stay in a 5-star hotel in St. Louis?
You'll find many different pricing options for a 5-star hotel in St. Louis on Expedia. The amount you pay will depend on your travel dates, trip length and other factors. Compare available accommodation for your desired dates and use our pricing and other filters to lock in the ideal high-end stay.

  • Search for the lowest price per night from 3.094.078 ₫

What makes a hotel 5 stars in St. Louis?
From gourmet dining venues and 24/7 fitness centres to pools and the finest bedding, the 5-star experience in St. Louis is all about indulgence and comfort. But it takes more than just upscale perks to earn a 5-star rating. Accommodation must also deliver remarkable guest-focused services like in-room massage treatments, on-site dry cleaning and laundry and a nightly turn-down service.