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Check availability on Central West End Business Hotels

Our top choices for Central West End business-friendly hotels

AC Hotel St. Louis Central West End

AC Hotel St. Louis Central West End
4.0 star property
Central West End
9.0 out of 10, Wonderful, (683)
"Clean room, Helpful staff, Easy/cheap parking "
United States
Delaney
The price is 3.340.989 ₫
3.939.995 ₫ total
includes taxes & fees
19 Dec - 20 Dec
AC Hotel St. Louis Central West End

DoubleTree by Hilton St. Louis Forest Park

DoubleTree by Hilton St. Louis Forest Park
4.0 star property
Central West End
8.2 out of 10, Very good, (1001)
"Great room "
United States
Jessica
The price is 2.869.041 ₫
3.383.432 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
DoubleTree by Hilton St. Louis Forest Park

The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
Central West End
9.0 out of 10, Wonderful, (1002)
"Always, a great time and place to stay."
United States
Lubna
The price is 4.182.813 ₫
5.708.279 ₫ total
includes taxes & fees
23 Dec - 24 Dec
The Royal Sonesta Chase Park Plaza St. Louis

Hotel Indigo St Louis - Central West End by IHG

Hotel Indigo St Louis - Central West End by IHG
3.5 star property
Central West End
8.2 out of 10, Very good, (1000)
"Very friendly staff. Clean modern hotel room with comfortable bed and spacious shower! "
United States
Courtney
The price is 3.051.612 ₫
3.887.324 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
Hotel Indigo St Louis - Central West End by IHG

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis
8.4 out of 10, Very good, (4009)
"Arch view room is big and comfortable fantastic. . "
United States
Tim
The price is 2.213.734 ₫
2.610.635 ₫ total
includes taxes & fees
27 Dec - 28 Dec
Hyatt Regency St. Louis at The Arch

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1149)
"Really nice hotel!"
United States
DARIN
The price is 2.296.601 ₫
2.731.323 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1015)
"My second time staying there as always it was lovely "
United States
Nina
The price is 2.714.882 ₫
3.201.633 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hilton Pennywell St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (3280)
"Our stay was very enjoyable. Location was great and kids loved the indoor pool!"
United States
Christy
The price is 3.551.182 ₫
4.152.361 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Drury Plaza Hotel St. Louis at the Arch

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay
3.5 star property
Clayton
8.8 out of 10, Excellent, (3032)
"Clean room, good breakfast and good location "
United States
Martin
The price is 2.387.886 ₫
2.787.752 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Clayton Plaza Hotel & Extended Stay

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
St. Louis
9.0 out of 10, Wonderful, (1447)
"Awesome place to stay!!"
United States
Kaitlyn
The price is 2.314.753 ₫
3.076.341 ₫ total
includes taxes & fees
21 Dec - 22 Dec
River City Casino & Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Central West End Hotel Reviews

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Frequently asked questions

Why book your business-friendly hotel in Central West End with Expedia?
We're here to help you find a fantastic business-friendly hotel when work takes you away from home. From conference spaces and meeting rooms to gyms and spas, our properties have the things you'll need to close that big deal.
How can I find cheap business-friendly hotels in Central West End?
When you're travelling for work in Central West End, our "business friendly" filter will help you find the right hotel. From free WiFi to concierge services and conference spaces, they come with the amenities you need for a productive and comfortable stay. You can also narrow your search by your preferred star rating and budget to view the cheapest options.