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Missouri Accommodation: Most Popular Cities to Stay

Union Station which includes heritage architecture, a city and a skyscraper
HotelsHotels

Kansas City

Kansas City

Check availability on Missouri Business Hotels

Tonight
26 Dec - 27 Dec
Tomorrow
27 Dec - 28 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

Our top choices for Missouri business-friendly hotels

Exterior
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay
3.5 star property
Clayton
8.8 out of 10, Excellent, (3038)
"Clean room, good breakfast and good location "
United States
Martin
The price is 2.499.318 ₫
2.917.624 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Clayton Plaza Hotel & Extended Stay
Lobby
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis
8.4 out of 10, Very good, (4027)
"Staff was supper nice and it all went so smooth."
United States
Brayden
The price is 2.601.918 ₫
3.068.415 ₫ total
includes taxes & fees
30 Dec - 31 Dec
Hyatt Regency St. Louis at The Arch
Restaurant
City Place St. Louis Downtown

City Place St. Louis Downtown

City Place St. Louis Downtown
2.5 star property
Downtown St. Louis
4.8 out of 10, (1003)
"Terrible everything. Don’t bring anything valuable or that you want to keep. There are no safes in room and CCTV is not for YOUR protection."
United States
Anonymous traveller
City Place St. Louis Downtown
Front of property – evening/night
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis
3.5 star property
Maryland Heights
8.4 out of 10, Very good, (2218)
"Front staff was very friendly and very helpful. Check-in and check out was smooth and very easy. "
United States
James
The price is 3.074.731 ₫
3.969.634 ₫ total
includes taxes & fees
26 Jan - 27 Jan 2026
Hollywood Casino & Hotel St. Louis
Exterior
Fairfield Inn Kansas City Downtown/Union Hill by Marriott

Fairfield Inn Kansas City Downtown/Union Hill by Marriott

Fairfield Inn Kansas City Downtown/Union Hill by Marriott
2.5 star property
Union Hill
8.6 out of 10, Excellent, (1000)
"Everything was great. The staff was excellent. "
United States
Kurt
The price is 2.233.970 ₫
2.716.869 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
Fairfield Inn Kansas City Downtown/Union Hill by Marriott
Lobby
Courtyard by Marriott St Louis Creve Coeur

Courtyard by Marriott St Louis Creve Coeur

Courtyard by Marriott St Louis Creve Coeur
3.0 star property
Creve Coeur
8.8 out of 10, Excellent, (1002)
"Clean room and very helpful staff"
United States
Amy
The price is 3.206.404 ₫
3.727.059 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Courtyard by Marriott St Louis Creve Coeur
Bar (on property)
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1166)
"Staff was helpful at suggesting places to eat and shop"
United States
Ann Marie
The price is 2.549.354 ₫
3.031.922 ₫ total
includes taxes & fees
25 Jan - 26 Jan 2026
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Ballroom
The Wildwood Hotel

The Wildwood Hotel

The Wildwood Hotel
3.5 star property
Wildwood
9.2 out of 10, Wonderful, (1610)
"Great place!"
United States
Biju
The Wildwood Hotel
Exterior
La Quinta Inn & Suites by Wyndham St. Louis Westport

La Quinta Inn & Suites by Wyndham St. Louis Westport

La Quinta Inn & Suites by Wyndham St. Louis Westport
3.0 star property
Maryland Heights
7.2 out of 10, Good, (1091)
"Front desk staff very friendly and efficient "
United States
Kathryn
The price is 2.152.496 ₫
2.496.636 ₫ total
includes taxes & fees
28 Dec - 29 Dec
La Quinta Inn & Suites by Wyndham St. Louis Westport
3 restaurants, breakfast, lunch, dinner served; American cuisine
Harrah's Kansas City Hotel and Casino - A Caesars Rewards Destination

Harrah's Kansas City Hotel and Casino - A Caesars Rewards Destination

Harrah's Kansas City Hotel and Casino - A Caesars Rewards Destination
3.5 star property
North Kansas City
7.6 out of 10, Good, (1004)
"The staff was amazing and our stay was alot of fun. "
United States
Richard
The price is 2.365.170 ₫
3.110.567 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Harrah's Kansas City Hotel and Casino - A Caesars Rewards Destination
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Missouri Hotel Reviews

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Frequently asked questions

How much do business-friendly hotels in Missouri cost?
Business-friendly hotels in Missouri range between 2.496.636 ₫ and 3.969.634 ₫ per night. This means you can lock in a stay with amenities like WiFi and workspaces at a price that won't break the bank. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in Missouri?
Missouri offers multiple business-friendly hotels with a total average guest review rating of 8.3. Have a work event in St. Louis? Drury Inn & Suites St. Louis Brentwood is a 3-stars property that's highly recommended by corporate travellers and features a swimming pool and laundry services. Another sought-after choice for an official business trip is Drury Plaza Hotel St. Louis at the Arch. Also located in St. Louis, it has a 3-stars rating and conveniences such as a terrace and a swimming pool.
How many business-friendly hotels are there in Missouri?
Select from 848 business-friendly hotels in Missouri. When you need to get down to work, Expedia makes it a cinch to find the ideal space with the amenities you need.
What are the best cheap business-friendly hotels in Missouri?
When work is taking you out of town in Missouri, Expedia will help you find the right business-friendly hotel. Hampton Inn & Suites St. Louis at Forest Park is a sought-after budget option in St. Louis. Pillow top mattresses and a swimming pool are among its many amenities. Searching for affordable accommodation in Kansas City? Hampton Inn & Suites Kansas City Downtown Crossroads is rated highly among corporate travellers. It has conveniences that make it easy to both work and relax, including a cafe and blackout curtains. Business-friendly hotels in Missouri start at only 2.496.636 ₫ per night. Combine business and leisure by visiting some fabulous free attractions on your work trip in Missouri. Forest Park in St. Louis is popular. If you're heading to Kansas City, you can leave your wallet in your pocket when visiting Crown Centre. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
Are there any family-friendly hotels in Missouri that are also business friendly?
You'll discover some fantastic family-friendly hotels that are also business friendly in Missouri. If you're travelling to St. Louis, check out Drury Plaza Hotel St. Louis at the Arch. It offers conveniences such as complimentary breakfast and laundry facilities and has a 3-stars rating. Or try Drury Inn & Suites St. Louis Forest Park. This 3-stars stay in St. Louis is ideal for both leisure and business travellers and features complimentary breakfast, WiFi and lots more. St. Louis has loads of family-friendly attractions when you're ready to discover the sights. St. Louis Zoo and Forest Park promise fun for everyone.
Are there any 5-star business-friendly hotels in Missouri?
Immerse yourself in luxury as you work at one of our 5-star business-friendly hotels in Missouri. Four Seasons Hotel St Louis in St. Louis sets the bar high. This 5-star retreat features a host of amenities, including a rooftop terrace and a sauna. You can also appreciate the finer things at The Ritz-Carlton, St. Louis. Business-friendly conveniences, designer toiletries and beauty services help make this a perfect base for corporate travellers visiting St. Louis.
Why book your business-friendly hotel in Missouri with Expedia?
Here at Expedia, our top task is to help you find an excellent stay at the right price. From fancy, corporate-friendly properties to affordable motor inns loaded with amenities, you'll have your next work trip planned in a few simple clicks.
How can I find cheap business-friendly hotels in Missouri?
When work takes you on the road in Missouri, our "business friendly" filter will help you find the ideal hotel. From dependable WiFi to meeting rooms and work desks, they come with the amenities you need for a comfortable and productive stay. Another tip? Narrow your search by your preferred star rating and budget to view the cheapest properties.
What is there to do in Missouri near my business-friendly hotel?
Whether you're into history, food, shopping or sightseeing, Missouri promises something for everyone! The popular city of St. Louis has tons of activities and attractions, including Fox Theatre, Anheuser-Busch Brewery and St. Louis Aquarium at Union Station. If you're planning a work trip to Kansas City, Crown Centre, Science City at Union Station and LEGOLAND® Discovery Centre should be at the top of your to-do list.