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Check availability on Central West End Spa Hotels

Our top choices for Central West End hotels with a spa

Hot tub, body treatments, hydrotherapy, aromatherapy, body scrubs
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.4 out of 10, Very good, (1003)
"Clean room, wonderful helpful pleasant staff, amenities, everything was great love staying here!"
United States
Robyn
The price is 4.010.218 ₫
5.123.802 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Ameristar Casino Resort and Spa
Massages
21C Museum Hotel St Louis

21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West
9.0 out of 10, Wonderful, (1491)
"Room was perfect and parking was a breeze. We really enjoyed the art was wonderful. "
United States
London
The price is 3.534.474 ₫
4.264.609 ₫ total
includes taxes & fees
18 Dec - 19 Dec
21C Museum Hotel St Louis
Couples treatment room(s), hot tub, body treatments, aromatherapy
Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1001)
"The staff was amazing. The bed was so comfortable. "
United States
Mary
The price is 10.938.155 ₫
12.789.875 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Four Seasons Hotel St Louis
Body treatments, aromatherapy, hot stone massages, deep-tissue massages
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
5.0 star property
Clayton
9.2 out of 10, Wonderful, (553)
"Service is exceptional!!!"
United States
Jorge
The price is 13.152.143 ₫
15.353.550 ₫ total
includes taxes & fees
23 Dec - 24 Dec
The Ritz-Carlton, St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in Central West End?
Treat yourself to some pampering and book a hotel with a spa. Travellers highly recommend the restaurants in Central West End. Take in the culture at the cathedral and museums during your stay. Hotels with spas are a great way to take a break from your routine and add a layer of luxury to your weekend away.
What's there to see and do in Central West End?
Enjoy all that Central West End has to offer and visit World Chess Hall of Fame, St. Louis Union Station and Gateway Arch. If you have extra time while you're in the area, you might want to stop by St. Louis Science Center and The Muny Theater.
What is a Central West End spa hotel?
Spa hotels in Central West End provide lodging and have a full on-site spa offering services such as massages as well as beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation and relaxation.