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Our top choices for Missouri hotels with a spa

The Elms Hotel & Spa, a Destination by Hyatt Hotel

The Elms Hotel & Spa, a Destination by Hyatt Hotel
4.0 star property
Excelsior Springs
8.6 out of 10, Excellent, (1002)
"Wonderful spa! "
United States
Michael
The price is 3.342.005 ₫
4.683.234 ₫ total
includes taxes & fees
20 Jan - 21 Jan 2026
The Elms Hotel & Spa, a Destination by Hyatt Hotel

Camden on the Lake Resort & Spa

Camden on the Lake Resort & Spa
4.0 star property
Lake Ozark
9.0 out of 10, Wonderful, (1002)
"Awesome staff, great food and service!!"
United States
Lori
Camden on the Lake Resort & Spa

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1001)
"Everything exceeded my expectations from the welcoming staff to the luxuriously appointed room, to the 4 feet deep bathtub in which to soak my cares away--it was a total dream come true. I would come back in a heartbeat at this home away from home. "
United States
Lynne
The price is 10.920.725 ₫
12.769.495 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Four Seasons Hotel St Louis

Margaritaville Lake Resort Lake of the Ozarks

Margaritaville Lake Resort Lake of the Ozarks
3.0 star property
Osage Beach
8.4 out of 10, Very good, (1000)
"My family and I had a wonderful time staying at this resort. The staff were very welcoming and helpful, and the rooms and facilities were all great. We really enjoyed our stay! "
United States
Amos
The price is 2.999.910 ₫
3.763.347 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Margaritaville Lake Resort Lake of the Ozarks

Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles
3.5 star property
St. Charles
8.8 out of 10, Excellent, (1015)
"I Loved it I would definitely stay there again"
United States
Roberta
The price is 3.215.167 ₫
3.695.095 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Embassy Suites by Hilton St. Louis St. Charles

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (3285)
"Our stay was very enjoyable. Location was great and kids loved the indoor pool!"
United States
Christy
The price is 3.552.262 ₫
4.153.625 ₫ total
includes taxes & fees
26 Dec - 27 Dec
Drury Plaza Hotel St. Louis at the Arch

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis
8.4 out of 10, Very good, (4032)
"Everything was great!"
United States
Kathryn
The price is 2.605.185 ₫
3.072.269 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Hyatt Regency St. Louis at The Arch

Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Hampton Inn & Suites Clayton/St. Louis-Galleria Area
3.0 star property
Clayton
9.0 out of 10, Wonderful, (915)
"Clean room, friendly staff."
United States
Patrick George
The price is 2.999.384 ₫
3.531.414 ₫ total
includes taxes & fees
19 Jan - 20 Jan 2026
Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Drury Inn & Suites St. Louis Arnold

Drury Inn & Suites St. Louis Arnold
3.0 star property
Arnold
9.6 out of 10, Exceptional, (1000)
"Clean room, comfortable bed, free breakfast, dinner and drinks every night! We had a great stay, will definitely stay again!"
United States
Jacqueline
The price is 3.236.482 ₫
3.741.204 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Drury Inn & Suites St. Louis Arnold

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
3.0 star property
Maryland Heights
7.4 out of 10, Good, (1009)
"Spacious suite, friendly staff. Check in was easy and everything looked clean"
United States
Jonathan
The price is 1.875.733 ₫
2.175.626 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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