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11 Dec - 12 Dec
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12 Dec - 13 Dec
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12 Dec - 14 Dec
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19 Dec - 21 Dec

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Our top choices for Downtown West hotels

Indoor pool
Drury Inn & Suites St. Louis Union Station

Drury Inn & Suites St. Louis Union Station

Drury Inn & Suites St. Louis Union Station
3.0 star property
Downtown West
9.4 out of 10, Exceptional, (1293)
"Great location and staff are friendly. "
United States
GARY
The price is 3.132.888 ₫
3.725.817 ₫ total
includes taxes & fees
26 Dec - 27 Dec
Drury Inn & Suites St. Louis Union Station
Lobby
Fairfield Inn & Suites by Marriott St. Louis Downtown

Fairfield Inn & Suites by Marriott St. Louis Downtown

Fairfield Inn & Suites by Marriott St. Louis Downtown
2.5 star property
Downtown West
9.2 out of 10, Wonderful, (1000)
"It is clean, staff are extremely helpful, fantastic location "
United States
David
The price is 2.817.203 ₫
3.361.793 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Fairfield Inn & Suites by Marriott St. Louis Downtown
Lobby
St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
4.0 star property
Downtown West
8.4 out of 10, Very good, (1006)
"Nice historic hotel"
United States
Michelle
The price is 3.739.004 ₫
4.446.759 ₫ total
includes taxes & fees
18 Dec - 19 Dec
St. Louis Union Station Hotel, Curio Collection by Hilton
Lobby
Home2 Suites by Hilton St. Louis Downtown

Home2 Suites by Hilton St. Louis Downtown

Home2 Suites by Hilton St. Louis Downtown
3.0 star property
Downtown West
8.0 out of 10, Very good, (595)
"A convenient location downtown with great rooms and services."
United States
Paul
The price is 2.001.004 ₫
2.339.754 ₫ total
includes taxes & fees
26 Dec - 27 Dec
Home2 Suites by Hilton St. Louis Downtown
Property amenity
Courtyard by Marriott St. Louis Downtown West

Courtyard by Marriott St. Louis Downtown West

Courtyard by Marriott St. Louis Downtown West
3.0 star property
Downtown West
8.6 out of 10, Excellent, (1001)
"Yes … room clean and staff very helpful"
United States
Jim
The price is 3.185.809 ₫
3.725.135 ₫ total
includes taxes & fees
26 Dec - 27 Dec
Courtyard by Marriott St. Louis Downtown West
Restaurant
21C Museum Hotel St Louis

21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West
9.0 out of 10, Wonderful, (1491)
"Room was perfect and parking was a breeze. We really enjoyed the art was wonderful. "
United States
London
The price is 3.534.474 ₫
4.264.609 ₫ total
includes taxes & fees
18 Dec - 19 Dec
21C Museum Hotel St Louis
Free daily buffet breakfast
Tru By Hilton St. Louis Downtown

Tru By Hilton St. Louis Downtown

Tru By Hilton St. Louis Downtown
2.5 star property
Downtown West
7.6 out of 10, Good, (581)
"Super friendly staff! Beautiful w3¹"
United States
Cassady
The price is 2.140.452 ₫
2.502.809 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Tru By Hilton St. Louis Downtown
Indoor pool
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station
3.0 star property
Downtown West
8.8 out of 10, Excellent, (1757)
"I had great stay "
United States
olubunmi
The price is 2.474.663 ₫
2.893.557 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Pear Tree Inn St. Louis Near Union Station
Exterior
Hilton St. Louis Frontenac

Hilton St. Louis Frontenac

Hilton St. Louis Frontenac
4.0 star property
17.3 km from Downtown West
8.8 out of 10, Excellent, (1000)
"Clean room, felt like a mini apartment! The surrounding was beautiful. "
United States
Jane
The price is 3.432.775 ₫
3.998.771 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton St. Louis Frontenac
Exterior
Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
2.5 star property
29.2 km from Downtown West
8.4 out of 10, Very good, (1002)
"Nice staff at reception. "
United States
Denise
The price is 2.077.986 ₫
2.388.167 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Comfort Suites St Charles - St Louis
Lobby
Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles
3.5 star property
30 km from Downtown West
8.8 out of 10, Excellent, (1012)
"I Loved it I would definitely stay there again"
United States
Roberta
The price is 3.563.466 ₫
4.095.385 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Embassy Suites by Hilton St. Louis St. Charles
Lobby
Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles
3.0 star property
29 km from Downtown West
9.6 out of 10, Exceptional, (1001)
"The stay was perfect. Very clean, quiet and comfortable. The staff were very friendly and helpful. I will stay again. "
United States
holly
The price is 3.027.572 ₫
3.509.656 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Drury Plaza Hotel St. Louis St. Charles
Lobby
Hampton Inn St. Louis - Columbia

Hampton Inn St. Louis - Columbia

Hampton Inn St. Louis - Columbia
2.5 star property
20.9 km from Downtown West
8.6 out of 10, Excellent, (476)
"Breakfast was great and a very good atten"
United States
John
The price is 2.298.330 ₫
2.550.687 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Hampton Inn St. Louis - Columbia
Lobby sitting area
Best Western Plus The Charles Hotel

Best Western Plus The Charles Hotel

Best Western Plus The Charles Hotel
3.0 star property
29.4 km from Downtown West
8.0 out of 10, Very good, (1000)
"It was perfect, and the staff were very helpful!"
United States
Susan
The price is 2.296.222 ₫
2.661.794 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Best Western Plus The Charles Hotel
Free daily buffet breakfast
Hampton Inn & Suites St. Charles Old Town Area

Hampton Inn & Suites St. Charles Old Town Area

Hampton Inn & Suites St. Charles Old Town Area
2.5 star property
29 km from Downtown West
9.2 out of 10, Wonderful, (627)
"Clean room, great staff, liked the gym"
United States
Emily
The price is 2.717.153 ₫
3.281.559 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Hampton Inn & Suites St. Charles Old Town Area
Exterior
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
29 km from Downtown West
9.4 out of 10, Exceptional, (1001)
"Love this hotel. "
United States
Lisa
The price is 3.124.199 ₫
3.590.549 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Country Inn & Suites by Radisson, St. Charles Historic District
Lobby
Drury Inn & Suites Southwest St. Louis

Drury Inn & Suites Southwest St. Louis

Drury Inn & Suites Southwest St. Louis
3.0 star property
27.2 km from Downtown West
9.4 out of 10, Exceptional, (1005)
"Clean room, breakfast, and friendly staff"
United States
Angie
The price is 3.027.572 ₫
3.541.777 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Drury Inn & Suites Southwest St. Louis
Lobby
Motel 6 Hazelwood, MO

Motel 6 Hazelwood, MO

Motel 6 Hazelwood, MO
2.0 star property
22.4 km from Downtown West
8.4 out of 10, Very good, (1606)
"great stay."
United States
Allison
The price is 1.507.357 ₫
1.842.618 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Motel 6 Hazelwood, MO
Room, 1 Queen Bed, Jetted Tub | Blackout curtains, free WiFi, bed sheets
Red Lion Inn & Suites Pontoon Beach

Red Lion Inn & Suites Pontoon Beach

Red Lion Inn & Suites Pontoon Beach
2.5 star property
18.9 km from Downtown West
7.8 out of 10, Good, (572)
"Room was clean, staff were really nice & helpful!! We will be back!"
United States
Shkaia
The price is 1.660.491 ₫
1.879.781 ₫ total
includes taxes & fees
13 Dec - 14 Dec
Red Lion Inn & Suites Pontoon Beach
Breakfast, dinner and brunch served
The Principal Hotel

The Principal Hotel

The Principal Hotel
3.5 star property
20.9 km from Downtown West
9.8 out of 10, Exceptional, (190)
"Great place. Very nice rooms, new and clean."
United States
Jeff
The price is 2.970.174 ₫
3.296.390 ₫ total
includes taxes & fees
25 Dec - 26 Dec
The Principal Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Downtown West

Find the best Downtown West areas for the activities you enjoy most.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Saint Louis Abbey while you're in town.

Central West End

Central West End

If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.

Top Downtown West Hotel Reviews

Explore a world of travel with Expedia

Frequently asked questions

What is Downtown West like?
Travellers are sure to enjoy a stay in St. Louis's Downtown West neighbourhood. Looking for sights you might find in a travel guide about Downtown West? Consider a visit to St. Louis Union Station while you're in the neighbourhood.
How many hotels will I find in the Downtown West area?
If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 34 Downtown West hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Downtown West, will I receive a refund?
Yes, you'll find most hotel room reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, it may still be possible to cancel it and get a refund within 24 hours of your booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to review top deals in Downtown West.
What is there to do in this St. Louis neighbourhood?
Browse the collections at City Museum, Campbell House Museum or Soldiers Memorial Museum in Downtown West. St. Louis Union Station and St. Louis Aquarium at Union Station are some other stops worth a visit in the neighbourhood. A few places to visit in the area around Downtown West include Gateway Arch, Whispering Arch at Union Station and St. Louis Union Station Mini Golf. While you're out sightseeing, The St. Louis Wheel and Energizer Park are a couple of additional sights to visit in St. Louis.
How can I get around Downtown West and the greater St. Louis area?
To venture out of town, take a train from St. Louis Gateway Station.