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12 Dec - 13 Dec
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13 Dec - 14 Dec
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12 Dec - 14 Dec
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19 Dec - 21 Dec

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Our top choices for East Seneca hotels

Terrace/patio
Roycroft Inn

Roycroft Inn

Roycroft Inn
3.5 star property
10.8 km from East Seneca
9.6 out of 10, Exceptional, (843)
"Always a great stay for a Bills weekend. Love the bar. "
United States
Christine
Roycroft Inn
Exterior
The Fields of Eden Inn

The Fields of Eden Inn

The Fields of Eden Inn
3.5 star property
25.4 km from East Seneca
9.8 out of 10, Exceptional, (93)
"Beautiful room, very comfortable, great location. Will definitely come back for future trips."
United States
Mark
The price is 3.659.731 ₫
4.089.684 ₫ total
includes taxes & fees
13 Jan - 14 Jan 2026
The Fields of Eden Inn
Exterior
The Mansion On Delaware Ave

The Mansion On Delaware Ave

The Mansion On Delaware Ave
4.0 star property
Allentown, 14.9 km from East Seneca
9.4 out of 10, Exceptional, (1000)
"Fantastic place!"
Canada
Geneviève
The Mansion On Delaware Ave
Fireplace
The Edward Hotel

The Edward Hotel

The Edward Hotel
3.0 star property
Elmwood Village, 15.8 km from East Seneca
9.6 out of 10, Exceptional, (217)
"Great location in Elmwood Village area. Clean room with gas fireplace. Self check- in was easy with staff provided instructions. Many food options within walking distance. "
United States
Jon
The Edward Hotel
Free daily continental breakfast
Salvatores Grand Hotel

Salvatores Grand Hotel

Salvatores Grand Hotel
3.0 star property
13.2 km from East Seneca
9.6 out of 10, Exceptional, (1004)
"It was beautiful and staff was wonderful."
United States
Sherry
The price is 4.449.601 ₫
5.061.487 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Salvatores Grand Hotel
Front of property
Clarence Inn

Clarence Inn

Clarence Inn
2.0 star property
15.7 km from East Seneca
8.0 out of 10, Very good, (293)
"Very nice place to stay. This is my third time staying here and I will be back again"
United States
kevin
The price is 2.606.571 ₫
2.912.843 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Clarence Inn
Free daily continental breakfast
Curtiss Hotel, an Ascend Collection Hotel

Curtiss Hotel, an Ascend Collection Hotel

Curtiss Hotel, an Ascend Collection Hotel
5.0 star property
Buffalo Theater District, 14.6 km from East Seneca
9.4 out of 10, Exceptional, (1002)
"Property and rooms are nice. "
United States
benjamin
The price is 5.477.748 ₫
6.395.270 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Curtiss Hotel, an Ascend Collection Hotel
2 bars/lounges
Aloft Buffalo Downtown

Aloft Buffalo Downtown

Aloft Buffalo Downtown
3.0 star property
Buffalo Theater District, 14.6 km from East Seneca
8.2 out of 10, Very good, (347)
"Clean room. Easy access to parking garage. "
United States
Clay
The price is 5.344.787 ₫
6.240.039 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Aloft Buffalo Downtown
Hallway
Hotel at the Lafayette Trademark Collection by Wyndham

Hotel at the Lafayette Trademark Collection by Wyndham

Hotel at the Lafayette Trademark Collection by Wyndham
3.5 star property
Buffalo Theater District, 14.3 km from East Seneca
8.6 out of 10, Excellent, (1002)
"I love the history in the hotel "
United States
Dylan
The price is 3.021.253 ₫
3.527.314 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Hotel at the Lafayette Trademark Collection by Wyndham
Front of property
Asa Ransom House

Asa Ransom House

Asa Ransom House
3.0 star property
18.7 km from East Seneca
9.6 out of 10, Exceptional, (203)
"Very enjoyable and relaxing stay. Great hospitality, exceptional breakfast; warmly decorated, clean and comfortable lodging. Highly recommend."
United States
Steven
The price is 3.659.731 ₫
4.294.238 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Asa Ransom House
Exterior
DoubleTree by Hilton Hotel Buffalo - Amherst

DoubleTree by Hilton Hotel Buffalo - Amherst

DoubleTree by Hilton Hotel Buffalo - Amherst
4.0 star property
18.5 km from East Seneca
7.8 out of 10, Good, (1000)
"The staff was friendly "
United States
ashley
The price is 2.414.983 ₫
2.747.043 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
DoubleTree by Hilton Hotel Buffalo - Amherst
Desk, blackout curtains, iron/ironing board, free cots/infant beds
Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG

Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG

Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG
2.5 star property
10.6 km from East Seneca
8.2 out of 10, Very good, (1006)
"It was a short, but nice stay."
United States
Sheila
The price is 2.185.307 ₫
2.485.787 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG
Lobby
The Westin Buffalo

The Westin Buffalo

The Westin Buffalo
4.0 star property
Buffalo Theater District, 14.8 km from East Seneca
9.2 out of 10, Wonderful, (399)
"Our go-to in Buffalo ,,"
Canada
Sarah
The price is 6.339.987 ₫
7.401.935 ₫ total
includes taxes & fees
24 Dec - 25 Dec
The Westin Buffalo
Lobby
Hilton Garden Inn Buffalo Airport

Hilton Garden Inn Buffalo Airport

Hilton Garden Inn Buffalo Airport
3.0 star property
10.8 km from East Seneca
9.0 out of 10, Wonderful, (1000)
"Clean rooms and friendly staff"
United States
Ellen
The price is 2.717.153 ₫
3.090.762 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hilton Garden Inn Buffalo Airport
Indoor pool
Comfort Inn & Suites Buffalo Airport

Comfort Inn & Suites Buffalo Airport

Comfort Inn & Suites Buffalo Airport
3.0 star property
10.9 km from East Seneca
8.2 out of 10, Very good, (1262)
"Very nice stay"
United States
James
The price is 2.613.943 ₫
2.973.360 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Comfort Inn & Suites Buffalo Airport
Exterior
Reikart House, Buffalo, a Tribute Portfolio Hotel

Reikart House, Buffalo, a Tribute Portfolio Hotel

Reikart House, Buffalo, a Tribute Portfolio Hotel
4.0 star property
14.7 km from East Seneca
9.6 out of 10, Exceptional, (682)
"Friendly staff, fast internet "
Canada
Kin Cheung Herbert
The price is 5.423.774 ₫
6.169.543 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Reikart House, Buffalo, a Tribute Portfolio Hotel
Suite, 1 King Bed, Non Smoking, Jetted Tub | Desk, laptop workspace, blackout curtains, iron/ironing board
Best Western on the Avenue

Best Western on the Avenue

Best Western on the Avenue
2.5 star property
Allentown, 15 km from East Seneca
8.6 out of 10, Excellent, (1000)
"The staff were the best part of the property. My room was quiet and they were quick to respond to request for more towels. Was safe and convenient to the airport and Buff State. "
United States
Ann
The price is 3.764.795 ₫
4.395.398 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Best Western on the Avenue
Serves dinner and happy hour
Aloft Buffalo Airport

Aloft Buffalo Airport

Aloft Buffalo Airport
3.0 star property
10.7 km from East Seneca
8.0 out of 10, Very good, (1002)
"Excellent, friendly staff!"
United States
Matthew
The price is 2.377.509 ₫
2.796.568 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Aloft Buffalo Airport
2 restaurants, dinner served
The Delavan Hotel & Spa

The Delavan Hotel & Spa

The Delavan Hotel & Spa
4.0 star property
11.4 km from East Seneca
8.8 out of 10, Excellent, (1003)
"Great location. Very spacious hotel, including the bathrooms. Friendly staff. Fun place to stay. "
United States
Michael
The Delavan Hotel & Spa
Terrace/patio
Buffalo Marriott Niagara

Buffalo Marriott Niagara

Buffalo Marriott Niagara
3.5 star property
18.3 km from East Seneca
8.4 out of 10, Very good, (1005)
"Yes we eat at the bar and the breakfast was good "
United States
Candy
The price is 2.814.849 ₫
3.201.890 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Buffalo Marriott Niagara
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in East Seneca

Find the best East Seneca areas for the activities you enjoy most.
Buffalo which includes a monument, a skyscraper and a city

Downtown Buffalo

Known for its great bars and great live music, there's plenty to explore in Downtown Buffalo. You can visit top attractions like Chippewa District and Statler Tower, and jump on the metro at Fountain Plaza Station or Lafayette Square Station to see more of the city.

Buffalo Theater District

Theatres, live music and restaurants highlight some notable features of Buffalo Theater District. Make a stop by Shea's Performing Arts Center or Chippewa District while you're visiting, and jump aboard the metro at Fountain Plaza Station or Lafayette Square Station to get around town.

Elmwood Village

Elmwood Village is known for its live music, and you can plan a trip to Blue Sky Mausoleum and Ujima Theatre Company while you're in town.

Delaware Park featuring a lake or waterhole

North Buffalo

North Buffalo is well liked for its live music and zoo. If you're hoping to get in some sightseeing, Buffalo Zoo and Buffalo History Museum are top spots, and you can jump on the metro at Amherst Street Station or Lasalle Station to get around.

Allentown

Allentown is noteworthy for its restaurants, and you can make a stop at top attractions like Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site and Theater of Youth.

Top East Seneca Hotel Reviews

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Frequently asked questions

What is East Seneca like?
Travellers will be sure to enjoy their time in West Seneca's East Seneca neighbourhood.
If I need to cancel my hotel reservation in East Seneca, will I receive a refund?
Yes! Most hotel reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you have a reservation that's non-refundable, it might still be possible to cancel it and receive a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to view the best deals in East Seneca.
What is there to do in this West Seneca neighbourhood?
A few places to visit in the area around East Seneca include Southgate Plaza, Harvest Hill Golf Course and Charles E. Burchfield Nature and Art Center. You might also plan a visit to Enjoy The Journey Art Gallery when you're sightseeing in West Seneca.