Search Hotels in Genessee-Moselle, Buffalo

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23 Dec - 24 Dec
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Our top choices for Genessee-Moselle hotels

Front of property
Clarence Inn

Clarence Inn

Clarence Inn
2.0 star property
15.1 km from Genessee-Moselle
8.2 out of 10, Very good, (294)
"Very nice place to stay. This is my third time staying here and I will be back again"
United States
kevin
The price is 2.605.185 ₫
2.911.294 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Clarence Inn
Lobby
Hampton Inn Lockport - Buffalo

Hampton Inn Lockport - Buffalo

Hampton Inn Lockport - Buffalo
2.5 star property
26.7 km from Genessee-Moselle
9.0 out of 10, Wonderful, (759)
"Clean room great staff"
United States
Shellie
The price is 2.842.020 ₫
3.211.483 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Hampton Inn Lockport - Buffalo
Terrace/patio
Lockport Inn & Suites

Lockport Inn & Suites

Lockport Inn & Suites
2.0 star property
29.6 km from Genessee-Moselle
9.2 out of 10, Wonderful, (1001)
"The staff was very nice and pleasant "
United States
Brandy
The price is 2.605.185 ₫
2.943.859 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Lockport Inn & Suites
Exterior
Holiday Inn Express Amherst - Lockport by IHG

Holiday Inn Express Amherst - Lockport by IHG

Holiday Inn Express Amherst - Lockport by IHG
2.5 star property
22.8 km from Genessee-Moselle
9.2 out of 10, Wonderful, (737)
"Room was super clean. Front desk was super friendly and helpful. Breakfast buffet was great. "
Canada
Terra
The price is 2.605.185 ₫
2.943.859 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express Amherst - Lockport by IHG
Exterior
CenterWay Hotel Tonawanda

CenterWay Hotel Tonawanda

CenterWay Hotel Tonawanda
2.0 star property
10.8 km from Genessee-Moselle
7.8 out of 10, Good, (1002)
" THIS is a good hotel."
United States
Chia Hung
The price is 1.578.663 ₫
1.795.910 ₫ total
includes taxes & fees
29 Dec - 30 Dec
CenterWay Hotel Tonawanda
Front of property
Staybridge Suites West Seneca by IHG

Staybridge Suites West Seneca by IHG

Staybridge Suites West Seneca by IHG
3.0 star property
8.5 km from Genessee-Moselle
9.0 out of 10, Wonderful, (866)
"Staff was great. The accommodations are really nice to have, such as the suite and kitchenette in the room. It made our stay very easy."
United States
Janine
The price is 4.605.125 ₫
5.238.330 ₫ total
includes taxes & fees
22 Jan - 23 Jan 2026
Staybridge Suites West Seneca by IHG
Indoor pool
Hampton Inn Buffalo South/I-90

Hampton Inn Buffalo South/I-90

Hampton Inn Buffalo South/I-90
2.5 star property
8.9 km from Genessee-Moselle
8.6 out of 10, Excellent, (1001)
"The hotel was quiet, room was nice and breakfast was really good. Lots of options to choose from! "
United States
Jeffrey B
The price is 3.215.167 ₫
3.657.254 ₫ total
includes taxes & fees
23 Jan - 24 Jan 2026
Hampton Inn Buffalo South/I-90
Exterior
Candlewood Suites Buffalo - Amherst by IHG

Candlewood Suites Buffalo - Amherst by IHG

Candlewood Suites Buffalo - Amherst by IHG
2.5 star property
9.5 km from Genessee-Moselle
8.6 out of 10, Excellent, (953)
"WE LOVE THIS HOTEL! The staff is always amazing and always so willing to help when needed. The rooms are always clean, and no bad smell anywhere in the hotel. The rooms come with just about anything you would need but the front desk has a borrow locker if needed. Good safe area, lots to do around. Seriously can't say enough good things about this hotel!!"
United States
Andrew
The price is 2.659.633 ₫
3.025.398 ₫ total
includes taxes & fees
29 Dec - 30 Dec
Candlewood Suites Buffalo - Amherst by IHG
Terrace/patio
Home2 Suites by Hilton Amherst Buffalo

Home2 Suites by Hilton Amherst Buffalo

Home2 Suites by Hilton Amherst Buffalo
3.0 star property
10.5 km from Genessee-Moselle
8.8 out of 10, Excellent, (1002)
"Clean hotel and friendly staff."
United States
Maxine
The price is 3.282.145 ₫
3.733.441 ₫ total
includes taxes & fees
21 Jan - 22 Jan 2026
Home2 Suites by Hilton Amherst Buffalo
Lobby sitting area
Fairfield Inn & Suites by Marriott Buffalo Amherst/University

Fairfield Inn & Suites by Marriott Buffalo Amherst/University

Fairfield Inn & Suites by Marriott Buffalo Amherst/University
2.5 star property
10 km from Genessee-Moselle
8.8 out of 10, Excellent, (709)
"Staff at the front desk were very personable and helpful. The room was spacious and had great amenities. "
Canada
Kristin
The price is 3.105.170 ₫
3.532.130 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Fairfield Inn & Suites by Marriott Buffalo Amherst/University
Fireplace
The Edward Hotel

The Edward Hotel

The Edward Hotel
3.0 star property
Elmwood Village, 4.3 km from Genessee-Moselle
9.6 out of 10, Exceptional, (219)
"Great location in Elmwood Village area. Clean room with gas fireplace. Self check- in was easy with staff provided instructions. Many food options within walking distance. "
United States
Jon
The Edward Hotel
View from property
Courtyard by Marriott Buffalo Amherst/University

Courtyard by Marriott Buffalo Amherst/University

Courtyard by Marriott Buffalo Amherst/University
3.0 star property
8.6 km from Genessee-Moselle
8.2 out of 10, Very good, (1001)
"Very comfy beds and pleasant front desk staff. "
Canada
Crystal
The price is 2.885.440 ₫
3.282.187 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
Courtyard by Marriott Buffalo Amherst/University
Lobby
The Mosey Buffalo Williamsville, Tapestry Collection by Hilton

The Mosey Buffalo Williamsville, Tapestry Collection by Hilton

The Mosey Buffalo Williamsville, Tapestry Collection by Hilton
4.0 star property
7.7 km from Genessee-Moselle
9.4 out of 10, Exceptional, (1000)
"Very clean and modern rooms. Great bar in the hotel. Overall great stay. "
United States
Rich
The price is 3.754.624 ₫
4.270.884 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
The Mosey Buffalo Williamsville, Tapestry Collection by Hilton
Indoor pool
Holiday Inn Express Hotel & Suites Hamburg by IHG

Holiday Inn Express Hotel & Suites Hamburg by IHG

Holiday Inn Express Hotel & Suites Hamburg by IHG
2.5 star property
18.7 km from Genessee-Moselle
8.8 out of 10, Excellent, (1003)
"Everything very welcoming from the hot soups, the beds, shower, to the breakfast "
United States
Vincent
The price is 2.868.335 ₫
3.262.731 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Holiday Inn Express Hotel & Suites Hamburg by IHG
Free daily on-the-go breakfast
Hampton Inn Buffalo-Hamburg

Hampton Inn Buffalo-Hamburg

Hampton Inn Buffalo-Hamburg
2.5 star property
18.8 km from Genessee-Moselle
9.0 out of 10, Wonderful, (1002)
"Room was very clean and staff friendly"
United States
Peter
The price is 2.589.396 ₫
2.945.437 ₫ total
includes taxes & fees
20 Jan - 21 Jan 2026
Hampton Inn Buffalo-Hamburg
Terrace/patio
Staybridge Suites Buffalo-Amherst by IHG

Staybridge Suites Buffalo-Amherst by IHG

Staybridge Suites Buffalo-Amherst by IHG
3.0 star property
10.1 km from Genessee-Moselle
9.0 out of 10, Wonderful, (1000)
"Right from the start from a great check in experience until we left everything was Fantastic. "
Canada
David
The price is 3.342.005 ₫
3.801.465 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Staybridge Suites Buffalo-Amherst by IHG
Hypo-allergenic bedding, in-room safe, desk, blackout curtains
Hampton Inn East Aurora

Hampton Inn East Aurora

Hampton Inn East Aurora
2.5 star property
23.2 km from Genessee-Moselle
9.4 out of 10, Exceptional, (984)
"Great place! easy parking , clean and quiet, nice breakfast and great staff"
United States
Mark
The price is 2.783.601 ₫
3.166.346 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Hampton Inn East Aurora
Terrace/patio
Roycroft Inn

Roycroft Inn

Roycroft Inn
3.5 star property
22.6 km from Genessee-Moselle
9.6 out of 10, Exceptional, (844)
"Always a great stay for a Bills weekend. Love the bar. "
United States
Christine
Roycroft Inn
Exterior
La Quinta Inn & Suites by Wyndham Lackawanna

La Quinta Inn & Suites by Wyndham Lackawanna

La Quinta Inn & Suites by Wyndham Lackawanna
3.0 star property
10.1 km from Genessee-Moselle
6.4 out of 10, (1007)
"Hotel and breakfast were very nice"
United States
Elizabeth
The price is 2.059.241 ₫
2.342.387 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
La Quinta Inn & Suites by Wyndham Lackawanna
Restaurant
Homewood Suites by Hilton Buffalo/Amherst

Homewood Suites by Hilton Buffalo/Amherst

Homewood Suites by Hilton Buffalo/Amherst
3.0 star property
8.7 km from Genessee-Moselle
9.0 out of 10, Wonderful, (1001)
"Very nice place to stay. It is clean, great staff, and pool. "
United States
Philip
The price is 3.631.470 ₫
4.130.798 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Homewood Suites by Hilton Buffalo/Amherst
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Genessee-Moselle

Find the best Genessee-Moselle areas for the activities you enjoy most.
Buffalo which includes a monument, a skyscraper and a city

Downtown Buffalo

Known for its great bars and great live music, there's plenty to explore in Downtown Buffalo. You can visit top attractions like Chippewa District and Statler Tower, and jump on the metro at Fountain Plaza Station or Lafayette Square Station to see more of the city.

Buffalo Theater District

Theatres, live music and restaurants highlight some notable features of Buffalo Theater District. Make a stop by Shea's Performing Arts Center or Chippewa District while you're visiting, and jump aboard the metro at Fountain Plaza Station or Lafayette Square Station to get around town.

Elmwood Village

Elmwood Village is known for its live music, and you can plan a trip to Blue Sky Mausoleum and Ujima Theatre Company while you're in town.

Delaware Park featuring a lake or waterhole

North Buffalo

North Buffalo is well liked for its live music and zoo. If you're hoping to get in some sightseeing, Buffalo Zoo and Buffalo History Museum are top spots, and you can jump on the metro at Amherst Street Station or Lasalle Station to get around.

Allentown

Allentown is noteworthy for its restaurants, and you can make a stop at top attractions like Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site and Theater of Youth.

Top Genessee-Moselle Hotel Reviews

Frequently asked questions

What's it like in Genessee-Moselle?
You'll be sure to have fun exploring Buffalo's Genessee-Moselle neighbourhood.
If I need to cancel my hotel reservation in Genessee-Moselle, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of booking. Enter your dates, click on "Search", then filter by "fully refundable" to view top deals in Genessee-Moselle.
What is there to do around this Buffalo neighbourhood?
Iron Island Museum, Buffalo Museum of Science and Buffalo Central Terminal are just a few of the places to visit in and around Genessee-Moselle. Broadway Market and Buffalo Fire Historical Society are also worth a visit when you're out sightseeing in Buffalo.