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Check availability on Grand Center Casino Hotels

Tonight
2 Dec - 3 Dec
Tomorrow
3 Dec - 4 Dec
This weekend
5 Dec - 7 Dec
Next weekend
12 Dec - 14 Dec

Top Grand Center Casino Hotels

Casino
River City Casino & Hotel

River City Casino & Hotel

4.0 star property
St. Louis
9.0 out of 10, Wonderful, (1454)
"Awesome place to stay!!"
United States
Kaitlyn
The price is 2.029.841 ₫
2.744.332 ₫ total
includes taxes & fees
9 Dec - 10 Dec
River City Casino & Hotel
Exterior
Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown

4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1246)
"Great hospitality"
United States
Alejandro
The price is 2.826.328 ₫
3.361.323 ₫ total
includes taxes & fees
9 Dec - 10 Dec
Embassy Suites by Hilton St. Louis Downtown
Exterior
Best Western Plus St. Louis Airport Hotel

Best Western Plus St. Louis Airport Hotel

2.5 star property
Woodson Terrace
9.2 out of 10, Wonderful, (1015)
"Love staying here every time I’m in Missouri "
United States
Claudia
The price is 2.890.922 ₫
3.575.823 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Best Western Plus St. Louis Airport Hotel
Free daily buffet breakfast
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

2.5 star property
St. Charles Historic District
9.4 out of 10, Exceptional, (1020)
"Love this hotel. "
United States
Lisa
The price is 3.102.633 ₫
3.565.764 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Country Inn & Suites by Radisson, St. Charles Historic District
Casino
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 star property
St. Charles
8.4 out of 10, Very good, (1015)
"Clean room, wonderful helpful pleasant staff, amenities, everything was great love staying here!"
United States
Robyn
The price is 3.776.041 ₫
4.850.051 ₫ total
includes taxes & fees
7 Dec - 8 Dec
Ameristar Casino Resort and Spa
Outdoor pool, open 8:00 AM to 8:30 PM, pool umbrellas, pool loungers
Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton

4.0 star property
Clayton
8.8 out of 10, Excellent, (675)
"Small rooms but beautiful lobby. "
United States
Debbie
The price is 3.142.708 ₫
3.700.162 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Le Méridien St. Louis Clayton
Lobby
Hampton Inn & Suites St. Charles Old Town Area

Hampton Inn & Suites St. Charles Old Town Area

2.5 star property
St. Charles
9.2 out of 10, Wonderful, (624)
"This was a very nice property. Clean, friendly employees, great breakfast, and a clean, well equipped room. Very comfortable "
United States
Katherine
The price is 2.510.329 ₫
3.041.994 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hampton Inn & Suites St. Charles Old Town Area
Lobby
AC Hotel St. Louis Central West End

AC Hotel St. Louis Central West End

4.0 star property
Central West End
9.0 out of 10, Wonderful, (680)
"Great staff. Rooms were super clean. 10/10 will stay here again"
United States
Jacob
The price is 3.348.863 ₫
3.949.280 ₫ total
includes taxes & fees
26 Dec - 27 Dec
AC Hotel St. Louis Central West End
Exterior
Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis

2.5 star property
St. Charles
8.4 out of 10, Very good, (1016)
"The staff was friendly "
United States
natalie
The price is 2.320.472 ₫
2.666.848 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Comfort Suites St Charles - St Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Grand Center Hotel Reviews

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Frequently asked questions

Searching for casino hotels in Grand Center?
Heading to Grand Center for some gaming? Lucky for you, you'll find Horseshoe St. Louis Casino, Casino Queen, and River City Casino in the area, plus much more to see and do. Visitors enjoy the theatres, entertainment venues and art galleries. You might want to visit popular sights in the larger area including St. Louis Union Station and Gateway Arch.
How many hotels that are good for gaming will I find in Grand Center?
Win big at one of Expedia's 31 hotels in Grand Center.
What is there to do in Grand Center?
You can head to Washington Avenue Historic District, Ballpark Village or Soulard Farmer's Market to shop for the perfect souvenir. Grand Center is known for its theatres, entertainment venues and art galleries, and you can visit cultural spots such as Sheldon Concert Hall and Fox Theater. For more to see and do, you can plan to visit Powell Symphony Hall and St. Louis Symphony Orchestra.