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18 Dec - 19 Dec
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19 Dec - 20 Dec
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19 Dec - 21 Dec
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Our top choices for Greenville Hospital System hotels

Exterior
Holiday Inn Express & Suites Greenville SE - Simpsonville by IHG

Holiday Inn Express & Suites Greenville SE - Simpsonville by IHG

Holiday Inn Express & Suites Greenville SE - Simpsonville by IHG
2.5 star property
1.3 km from Greenville Hospital System
9.4 out of 10, Exceptional, (511)
"Friendly staff and everything was well kept."
United States
Ronny
The price is 3.633.678 ₫
3.997.046 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Holiday Inn Express & Suites Greenville SE - Simpsonville by IHG
Lobby lounge
Fairfield Inn & Suites by Marriott Greenville Simpsonville

Fairfield Inn & Suites by Marriott Greenville Simpsonville

Fairfield Inn & Suites by Marriott Greenville Simpsonville
2.5 star property
0.9 km from Greenville Hospital System
9.2 out of 10, Wonderful, (665)
"Hotel is good, just not excellent. I would stay here again."
United States
Catherine
The price is 2.663.381 ₫
2.929.718 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Fairfield Inn & Suites by Marriott Greenville Simpsonville
Exterior
Hampton Inn Simpsonville

Hampton Inn Simpsonville

Hampton Inn Simpsonville
2.5 star property
0.7 km from Greenville Hospital System
8.8 out of 10, Excellent, (591)
"Everyone was very courteous. Room was very nice. Continental breakfast was excellent every morning."
United States
Karla
The price is 2.677.336 ₫
3.167.567 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Hampton Inn Simpsonville
Lobby
Comfort Suites Simpsonville - Greenville

Comfort Suites Simpsonville - Greenville

Comfort Suites Simpsonville - Greenville
2.5 star property
1.5 km from Greenville Hospital System
8.2 out of 10, Very good, (774)
"Great stay! Just wish there would have been a few more healthy breakfast food choices "
United States
Elizabeth
The price is 2.887.194 ₫
3.175.914 ₫ total
includes taxes & fees
18 Jan - 19 Jan 2026
Comfort Suites Simpsonville - Greenville
Seasonal outdoor pool, open 9 AM to 10:00 PM, pool loungers
Quality Inn Simpsonville - Greenville

Quality Inn Simpsonville - Greenville

Quality Inn Simpsonville - Greenville
2.5 star property
0.8 km from Greenville Hospital System
7.4 out of 10, Good, (160)
"Clean and great for the price. Breakfast was sub par though."
United States
Stephen
The price is 1.625.676 ₫
1.893.567 ₫ total
includes taxes & fees
18 Jan - 19 Jan 2026
Quality Inn Simpsonville - Greenville
Exterior
Motel 6 Simpsonville, SC - Greenville

Motel 6 Simpsonville, SC - Greenville

Motel 6 Simpsonville, SC - Greenville
2.0 star property
0.9 km from Greenville Hospital System
7.4 out of 10, Good, (353)
"Good son was happy "
United States
Samuel
The price is 1.842.907 ₫
2.027.224 ₫ total
includes taxes & fees
20 Dec - 21 Dec
Motel 6 Simpsonville, SC - Greenville
Exterior
Days Inn by Wyndham Simpsonville

Days Inn by Wyndham Simpsonville

Days Inn by Wyndham Simpsonville
2.0 star property
0.8 km from Greenville Hospital System
7.2 out of 10, Good, (415)
"Breakfast was limited, rooms were ok, staff okay and nice. Bed had a smoke hole in the sheets. "
United States
Rudes
The price is 1.843.170 ₫
2.027.486 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Days Inn by Wyndham Simpsonville
Exterior
WoodSpring Suites Greenville Simpsonville

WoodSpring Suites Greenville Simpsonville

WoodSpring Suites Greenville Simpsonville
2.5 star property
2.8 km from Greenville Hospital System
7.0 out of 10, Good, (158)
"Was a good stay no issues "
United States
Kevin
The price is 1.816.839 ₫
1.998.523 ₫ total
includes taxes & fees
20 Dec - 21 Dec
WoodSpring Suites Greenville Simpsonville
Restaurant
Hotel Hartness

Hotel Hartness

Hotel Hartness
4.0 star property
13.6 km from Greenville Hospital System
9.8 out of 10, Exceptional, (630)
"Beautiful location, friendly staff"
United States
Andrew
The price is 3.984.934 ₫
5.272.520 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hotel Hartness
Restaurant
Courtyard by Marriott Greenville Mauldin

Courtyard by Marriott Greenville Mauldin

Courtyard by Marriott Greenville Mauldin
3.0 star property
10 km from Greenville Hospital System
9.2 out of 10, Wonderful, (300)
"Excellent stay "
United States
Shellie
The price is 2.738.424 ₫
3.012.266 ₫ total
includes taxes & fees
20 Dec - 21 Dec
Courtyard by Marriott Greenville Mauldin
Exterior
DoubleTree by Hilton Greenville Woodruff Road

DoubleTree by Hilton Greenville Woodruff Road

DoubleTree by Hilton Greenville Woodruff Road
3.0 star property
12.6 km from Greenville Hospital System
9.4 out of 10, Exceptional, (1010)
"Clean modern comfortable convenient location great cookie "
United States
Jimmy
The price is 2.663.381 ₫
2.929.720 ₫ total
includes taxes & fees
24 Dec - 25 Dec
DoubleTree by Hilton Greenville Woodruff Road
Indoor pool, outdoor pool
Drury Inn & Suites Greenville

Drury Inn & Suites Greenville

Drury Inn & Suites Greenville
3.0 star property
12.8 km from Greenville Hospital System
9.4 out of 10, Exceptional, (1001)
"Very nice amenities and rooms. Staff was super friendly and very helpful when needed. We will definitely stay at another Drury Inn when traveling or needing a hotel"
United States
Blair
The price is 2.922.478 ₫
3.214.752 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Drury Inn & Suites Greenville
Exterior
Staybridge Suites Greenville I-85 Woodruff Road by IHG

Staybridge Suites Greenville I-85 Woodruff Road by IHG

Staybridge Suites Greenville I-85 Woodruff Road by IHG
3.0 star property
12.3 km from Greenville Hospital System
9.2 out of 10, Wonderful, (317)
"Wonderful hotel would definitely recommend. "
United States
laura nejude
The price is 4.056.206 ₫
4.461.828 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Staybridge Suites Greenville I-85 Woodruff Road by IHG
Lobby
Tru by Hilton Greenville Woodruff Road

Tru by Hilton Greenville Woodruff Road

Tru by Hilton Greenville Woodruff Road
2.5 star property
12.8 km from Greenville Hospital System
9.2 out of 10, Wonderful, (286)
"Very clean property felt welcoming staff was great"
United States
Christopher
The price is 2.450.581 ₫
2.944.544 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Tru by Hilton Greenville Woodruff Road
Property amenity
Residence Inn by Marriott Greenville

Residence Inn by Marriott Greenville

Residence Inn by Marriott Greenville
3.0 star property
12.8 km from Greenville Hospital System
9.2 out of 10, Wonderful, (449)
"Comfortable bed, great location, great water pressure "
United States
Brad
The price is 3.396.699 ₫
3.736.369 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Residence Inn by Marriott Greenville
Individually decorated, individually furnished, desk, laptop workspace
Comfort Suites Greenville Airport

Comfort Suites Greenville Airport

Comfort Suites Greenville Airport
2.5 star property
15.1 km from Greenville Hospital System
9.4 out of 10, Exceptional, (1003)
"Clean room and very friendly front desk staff"
United States
Lakisha
The price is 2.476.167 ₫
2.798.070 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Comfort Suites Greenville Airport
BBQ/picnic Area
Hilton Garden Inn Greenville

Hilton Garden Inn Greenville

Hilton Garden Inn Greenville
3.0 star property
12.8 km from Greenville Hospital System
9.0 out of 10, Wonderful, (999)
"Great service and great room"
United States
warren
The price is 2.353.465 ₫
2.666.476 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Hilton Garden Inn Greenville
Free daily buffet breakfast
Homewood Suites by Hilton Greenville

Homewood Suites by Hilton Greenville

Homewood Suites by Hilton Greenville
3.0 star property
12.8 km from Greenville Hospital System
9.0 out of 10, Wonderful, (393)
"Very cleaned and great breakfast selection "
United States
Pedro
The price is 3.002.119 ₫
3.401.402 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Homewood Suites by Hilton Greenville
Exterior
Pettigru Place Bed & Breakfast

Pettigru Place Bed & Breakfast

Pettigru Place Bed & Breakfast
3.5 star property
19.3 km from Greenville Hospital System
10.0 out of 10, Exceptional, (125)
"Room was great, clean and comfortable. Staff was outstanding. Great breakfast as well. Super place to stay "
United States
Blake
The price is 5.478.512 ₫
6.026.363 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Pettigru Place Bed & Breakfast
Free daily buffet breakfast
Hampton Inn Greenville I-385 - Woodruff Rd.

Hampton Inn Greenville I-385 - Woodruff Rd.

Hampton Inn Greenville I-385 - Woodruff Rd.
3.0 star property
12.1 km from Greenville Hospital System
8.8 out of 10, Excellent, (788)
"Vanessa and Rhonda were excellent hosts and made our stay very comfortable!!"
United States
Victor L
The price is 2.677.336 ₫
3.033.423 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Hampton Inn Greenville I-385 - Woodruff Rd.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Greenville Hospital System Hotel Reviews

Hotels near other Greenville Hospital System attractions

Fairview Station

You can enjoy retail therapy at Fairview Station during your trip to Simpsonville. Take in the live music and sunrises in the area.
See properties

Piedmont Plaza

You can browse for the perfect souvenirs at Piedmont Plaza during your stay in Simpsonville. Experience the area's live music and theatre scene.
See properties

Frequently asked questions

What's the area like around Greenville Hospital System?
Greenville Hospital System is located in Simpsonville. If you're looking for a convenient place to stay, take a look at the 14 hotels and other accommodation options you'll find within a mile.
How many hotels should I expect to find near Greenville Hospital System?
Expedia has 14 hotels and other accommodation options within a mile from Greenville Hospital System.
If I need to cancel the hotel reservation for my stay near Greenville Hospital System, will I receive a refund?
Yes, you'll find most hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If your reservation is non-refundable, you might be able to still cancel and be given a refund within a 24-hour period of booking. Add your dates and click on "Search", then filter by "fully refundable" to view top deals close to Greenville Hospital System.
What can I see and do near Greenville Hospital System?
You can watch performances at Heritage Park, Younts Center for Performing Arts and CCNB Amphitheatre if you're interested in local theatre. Create some family memories at Discovery Island Water Park and Golden Lanes and Golden Skate. A shopping trip to The Market at Standing Springs, Beck Plaza or Bradford Plaza might be the perfect place to find that souvenir you've been looking for.