Visit South Main
Popular places to visit
George R. Brown Convention Center
During your trip, find out what's happening in George R. Brown Convention Center, a top convention centre in Houston. Experience the acclaimed theatre scene and entertainment choices in this vibrant area.
NASA Johnson Space Center
After visiting NASA Johnson Space Center, make a plan to see the other sights and activities in Houston. Amble around the area's lakeside or attend a sporting event.
Toyota Center
Catch an event at Toyota Center during your trip to Houston. Experience the entertainment choices and great live music in this vibrant area.
Rice University
Walk around the campus of Rice University, a top university in Houston. Experience the area's lively festivals and fascinating museums.
Space Center Houston
You can spend time exploring the galleries in Space Center Houston during your trip to Houston. Amble around the area's lakeside or attend a sporting event.
Daikin Park
Catch an event at Daikin Park during your trip to Houston. Experience the acclaimed art galleries and entertainment choices in this vibrant area.
Top hotels in South Main
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
The room was nice, comfy bed, great views
Reviewed on 24 Nov 2025
The Royal Sonesta Houston Galleria
Beautiful hotel, delicious breakfast, and great service. The bathroom was not the best in my hotel room.
Reviewed on 24 Nov 2025
The Whitehall Houston
Room was old and smelled
Reviewed on 26 Nov 2025
Holiday Inn Houston Downtown by IHG
The room was clean. Expected a cleaner toilet bowl.
Reviewed on 25 Nov 2025
Blossom Hotel Houston, Curio Collection by Hilton
Everything was great!!
Reviewed on 26 Nov 2025
Magnolia Hotel Houston, A Tribute Portfolio Hotel
Friendly service and great view
Reviewed on 21 Nov 2025
Other neighbourhoods around South Main
Astrodome
While you're in Astrodome, take in top sights like NRG Stadium or NRG Astrodome, and hop on the metro to see more of the city at Stadium Park/Astrodome Station or Smith Lands Station.
Texas Medical Center
Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.
Museum District
Known for its abundant dining options and interesting museums, there's plenty to explore in Museum District. Top attractions like Children's Museum of Houston and Houston Natural Science Museum are major draws, and you can catch the metro at M. D. Anderson Station or Museum District Station to see more of the city.
South Central Houston
If you're spending time in South Central Houston, check out sights like Continental Club or Midtown Arts and Theater Center Houston and hop on the metro to see more of the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.
Montrose
Unique features of Montrose include the theatres and museums. Make a stop by Menil Collection or Houston Center for Photography while you're exploring the area.
River Oaks
Gardens and monuments are just a few things travellers like about River Oaks. A stop by River Oaks Country Club is also recommended if you've got time to explore the area.
South Main Travel Guide
- George R. Brown Convention Center
- NRG Stadium
- MD Anderson Cancer Center
- Toyota Center
- Rice University
- Daikin Park
- Houston Zoo
- University of Houston
- Westheimer Road
- Memorial City Mall
- CityCentre
- Downtown Aquarium
- NRG Park
- Discovery Green
- House of Blues Houston
- Hobby Center for the Performing Arts
- Houston Natural Science Museum
- Texas Southern University
- Sam Houston Race Park
- Baybrook Mall
- Houston Museum of Fine Arts
- Richmond Avenue
- Pearland Town Center
- Lakewood Church
- Memorial Park
- The Galleria
