The Best Hotels Closest to Louisville Science Center in Louisville - 2026 Updated Prices

The entrance to the Kentucky Science Center with a large circular structure in the foreground.

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Our top choices for Louisville Science Center hotels

A grand staircase with a wooden handrail and carpeted steps, leading to an upper floor.

A building entrance with a dark door, a large number '1332' above it, and two large potted ferns on either side.

A living room with a sofa, armchair, coffee table, fireplace, and large windows.

A covered outdoor seating area with wicker furniture and a wooden railing.

1. Louisville Bourbon Inn

Old Louisville, 2.9 km from Louisville Science Center

Roy

7.246.746 ₫

8.411.297 ₫ total

includes taxes & fees

5 Oct - 6 Oct

A wooden staircase with a balustrade leading to a landing.

A bedroom with a bed, a dresser, a television, and a desk with a lamp.

A brick building with a covered porch, columns, and potted plants.

A dining area with brick walls, wooden shelves, and tables set for a meal.

2. Market Street Inn

2.1 km from Louisville Science Center

Holly

5.081.034 ₫

5.741.553 ₫ total

includes taxes & fees

29 Sept - 30 Sept

A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.

A living room with a sofa, a fireplace, a staircase, and a chandelier.

A room with a large mirror, a wooden dresser, a red patterned rug, and a door with a wreath.

An outdoor patio with red furniture, including a table and chairs, and two red umbrellas providing shade.

3. DuPont Mansion Bed & Breakfast

Old Louisville, 2.8 km from Louisville Science Center

Casey

4.731.424 ₫

5.491.765 ₫ total

includes taxes & fees

29 Sept - 30 Sept

A grand lobby with ornate columns, plush seating, and a chandelier.

A grand lobby with ornate ceiling, multiple seating areas, and a staircase.

A grand dining area with ornate ceiling, chandeliers, and a bar area with a sign reading "Cigar Bar".

A grand lobby with ornate ceiling, large windows, and classic furniture.

4. The Brown Hotel

Downtown Louisville, 1.2 km from Louisville Science Center

Meghan

3.487.009 ₫

4.102.815 ₫ total

includes taxes & fees

29 Oct - 30 Oct

A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.

A modern hotel with multiple floors, large windows, and a prominent sign for Homewood Suites.

A swimming pool with lounge chairs and a view of the city.

A spacious lobby with a large seating area, a chandelier, and a patterned rug.

5. Homewood Suites by Hilton Louisville Downtown, KY

Downtown Louisville, 0.2 km from Louisville Science Center

Kelly

3.132.724 ₫

3.685.963 ₫ total

includes taxes & fees

25 Oct - 26 Oct

An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.

An outdoor dining area with tables and chairs, a green building facade, and a row of plants along the wall.

A multi-story hotel with a classic facade, large windows, and a modern glass building adjacent to it.

A modern living room with a leather sectional sofa, a glass coffee table, and a view of the city skyline through large windows.

6. Hotel Distil, Autograph Collection

Downtown Louisville, 0.9 km from Louisville Science Center

Adam

6.148.565 ₫

7.234.402 ₫ total

includes taxes & fees

29 Oct - 30 Oct

An outdoor terrace with tables and chairs, large windows, and a view of the city skyline at sunset.

A modern hotel lobby with a reception desk, seating area, and a large abstract ceiling artwork.

A modern restaurant with high tables and booths, wooden ceiling panels, and framed pictures on the walls.

A modern hotel room with a large bed, a desk with a chair, a flat-screen TV, and a large window offering a city view.

7. Tempo By Hilton Louisville Downtown Nulu

Phoenix Hill, 2.1 km from Louisville Science Center

Addison

3.173.503 ₫

3.733.943 ₫ total

includes taxes & fees

4 Oct - 5 Oct

An outdoor seating area with sofas and tables, a fire feature, and a clock tower in the background.

A modern hotel room with a large bed, a city view, and a unique headboard design.

A hotel with a prominent sign, a central courtyard with a sculpture, and a dome structure in the background.

A modern lobby with a central reception desk, seating area, and a large abstract wall art piece.

8. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Downtown Louisville, 0.8 km from Louisville Science Center

Cameron

5.516.358 ₫

6.490.549 ₫ total

includes taxes & fees

11 Oct - 12 Oct

A modern hotel lobby with a reception desk, seating area, and a staircase leading to the upper floor.

A modern, well-lit room with a large bed, a green sofa, a small round table, and a kitchen area in the background.

A modern interior with a green wall, black chairs, and a ceiling with exposed beams and lights.

A modern bedroom with a bed, a blue sofa, a large rug, and a TV on the wall.

9. Stellar Suites

East Market District, 2.2 km from Louisville Science Center

Benton

2.553.893 ₫

4.320.964 ₫ total

includes taxes & fees

29 Sept - 30 Sept

A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.

A modern restaurant interior with a staircase, round tables, and a brick wall.

A building with a sign reading "THE GRADY" at the entrance.

A modern hotel room with a large bed, a desk with a flat-screen TV, a green armchair, and a view of the city through large windows.

10. The Grady

Downtown Louisville, 0.2 km from Louisville Science Center

Bruce

4.538.957 ₫

5.340.536 ₫ total

includes taxes & fees

11 Oct - 12 Oct

An outdoor seating area with wicker furniture and a fire pit.

A modern lounge area with seating, tables, and a view of the city through large windows.

A modern living room with a sofa, armchairs, a coffee table, and a TV.

An indoor swimming pool with clear water, a diving board, and lounge chairs around the pool area.

11. Towneplace Suites By Marriott Louisville Downtown

Downtown Louisville, 0.3 km from Louisville Science Center

Scott

2.857.140 ₫

3.361.711 ₫ total

includes taxes & fees

25 Oct - 26 Oct

An indoor dining area with wooden tables and chairs, a bar area, and a view of the street outside.

A modern lounge area with a pool table, comfortable seating, a fireplace, and a brick accent wall.

A modern hotel with a prominent 'Aloft Hotels' sign, multiple floors, and a corner location with a view of the city skyline.

A modern coffee shop interior with a central island, wooden counter, and large windows.

12. Aloft by Marriott Louisville Downtown

Downtown Louisville, 0.9 km from Louisville Science Center

Angela

3.444.412 ₫

4.052.723 ₫ total

includes taxes & fees

4 Oct - 5 Oct

A room with a checkered floor, leather armchairs, a sofa, and a small table with a glass. There are windows with arched tops and a view of buildings outside.

A bedroom with a bed, a chair, a TV, and a window with curtains.

A bar area with a wooden bar counter, two stools, a chandelier, and a mirror.

A brightly lit grocery store with yellow shelving and a central checkout counter.

13. Hotel Genevieve part of JdV by Hyatt

East Market District, 2.1 km from Louisville Science Center

Tyler

3.948.048 ₫

4.645.272 ₫ total

includes taxes & fees

4 Oct - 5 Oct

A bar area with a neon 'CHECK IN' sign, a variety of liquor bottles, and a modern seating arrangement.

A modern hotel room with a large bed, a desk with a chair, a TV mounted on the wall, and a window with a city view.

A modern hotel with a prominent 'Marriott' sign, large windows, and a brick facade.

A cozy living room with a fireplace, a black leather sofa, and a patterned rug.

14. Moxy Louisville Downtown

Downtown Louisville, 0.9 km from Louisville Science Center

Bryan

3.324.672 ₫

3.911.809 ₫ total

includes taxes & fees

11 Oct - 12 Oct

A modern bar area with a marble countertop, seating, and a central bar stocked with bottles.

A modern hotel building with a prominent AC Hotel NULU sign, multiple floors, and a well-lit entrance.

A modern restaurant with high ceilings, large windows, and a mix of round and rectangular tables.

A modern hotel lobby with a reception desk, seating area, and a large window providing natural light.

15. AC Hotel Louisville Downtown

East Market District, 2.1 km from Louisville Science Center

Jen

3.833.762 ₫

4.510.805 ₫ total

includes taxes & fees

25 Oct - 26 Oct

A modern interior with large windows offering a city view, a circular light fixture, and leather seating.

A modern bar with a long counter, multiple shelves of liquor bottles, and cushioned bar stools.

A spacious room with a large dining table, comfortable seating, a sofa, and a view of a bridge.

A nighttime view of The GALT and The Galthouse buildings with illuminated signage, a busy street with light trails from moving vehicles, and a modern urban setting.

16. Galt House Hotel Trademark Collection by Wyndham

Downtown Louisville, 0.5 km from Louisville Science Center

Saud

3.906.490 ₫

4.596.359 ₫ total

includes taxes & fees

27 Oct - 28 Oct

A covered patio with a stone wall, a glass table, and a bench.

A grand room with a fireplace, a staircase, and a chandelier.

A garden pathway with a lantern, potted plants, and a white fence.

17. Central Park Bed & Breakfast

Old Louisville, 3 km from Louisville Science Center

Brittany

4.435.580 ₫

5.148.566 ₫ total

includes taxes & fees

29 Sept - 30 Sept

A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.

A hotel dining area with long tables, booths, and a bar.

A modern bar area with a long counter, multiple chairs, and a bookshelf filled with bottles.

A modern hotel room with a living area, a dining area, and a bedroom.

18. Embassy Suites Louisville Downtown

Downtown Louisville, 0.8 km from Louisville Science Center

Maurica

3.535.581 ₫

4.159.965 ₫ total

includes taxes & fees

29 Oct - 30 Oct

A modern building with a restaurant on the ground floor, featuring large windows and outdoor seating.

A modern bar area with glass partitions, bar stools, and a variety of bottles.

A spacious lobby with a bar area, seating arrangements, and a visible kitchen bar.

A modern hotel room with a large window offering a city view, a cozy seating area with a sofa and chairs, a dining table with lamps, and a wooden floor.

19. Louisville Marriott Downtown

Downtown Louisville, 0.8 km from Louisville Science Center

Jacobi

5.562.072 ₫

6.544.333 ₫ total

includes taxes & fees

12 Oct - 13 Oct

A modern interior with a curved wall featuring vertical lines and geometric patterns.

A modern lobby with a curved seating area, a red ottoman, and a television screen.

A hotel room with two beds, a wooden headboard, bedside lamps, a small table, and a patterned rug.

20. Holiday Inn Express & Suites Louisville Downtown by IHG

Downtown Louisville, 0.2 km from Louisville Science Center

Carlos

2.727.270 ₫

3.208.906 ₫ total

includes taxes & fees

25 Oct - 26 Oct

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Compare popular hotels close to Louisville Science Center

Property	Property class	Guest rating
Louisville Bourbon Inn	10.0 Exceptional 25 reviews	View
Market Street Inn	9.8 Exceptional 125 reviews	View
DuPont Mansion Bed & Breakfast	9.6 Exceptional 147 reviews	View
The Brown Hotel	9.4 Exceptional 1,332 reviews	View
Homewood Suites by Hilton Louisville Downtown, KY	9.4 Exceptional 1,006 reviews	View

Top Louisville Science Center Hotel Reviews

Holiday Inn Louisville Downtown by IHG

8/10 Good

"Lots of key trouble, kept having to get keys re-activated. Staff was good and the hotel grounds/common areas/rooms were updated and nice."

Embassy Suites Louisville Downtown

10/10 Excellent

"Staff was super helpful. Breakfast was delicious! Clean property and good location"

Holiday Inn Express & Suites Louisville Downtown by IHG

10/10 Excellent

"Great place"

Radisson Hotel Louisville North

8/10 Good

"Service is good"

Homewood Suites by Hilton Louisville Downtown, KY

10/10 Excellent

"Everything was tidy and welcoming. Staff was very nice and helpful."

The Reserve on Main

10/10 Excellent

"The location was fantastic, the building, guest rooms, and common areas were in pristine condition, very clean, sleek design, well stocked with everything you could possibly need. Really enjoyed the speak easy in the lower level and the opportunity to have a nightcap in the private lounge on our floor. We appreciated the security system build into the elevator to limit access to only hotel guests. We could not have been more pleased with our stay. The owners communicated well and were helpful in answering questions. Highly recommend!!!"

Cambria Hotel Louisville Downtown-Whiskey Row

8/10 Good

"We really liked the location of the hotel. It was nice to have a restaurant and bar on property as well. Two complaints would be water pressure in the shower and you could hear your neighbors. They weren’t being loud either; not sure if walls were thin!"

Hyatt Regency Louisville

10/10 Excellent

"Friendly staff, great location, easy parking, breakfast was good, clean"

Moxy Louisville Downtown

8/10 Good

"No way to get hot water for tea for guests."

Other attractions near Louisville Science Center

A tall wooden baseball bat leaning against a brick building with a sign reading "Hillerich & Brassler Co."

Louisville Slugger Museum

9.2/10 (2,299 reviews)

You can spend an afternoon studying the exhibits at Louisville Slugger Museum during your travels in Louisville. Amble around the area's riverfront or attend a sporting event.

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A modern building with a cylindrical structure and a glass facade.

Muhammad Ali Center

8.8/10 (295 reviews)

You can spend an afternoon browsing the exhibits at Muhammad Ali Center during your travels in Louisville. Stroll along the area's riverfront or experience its lively festivals.

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The Frazier History Museum with red doors and a tree in front.

Frazier International History Museum

9.4/10 (10 reviews)

You can spend an afternoon exploring the galleries in Frazier International History Museum during your trip to Louisville. Stroll along the riverfront or attend a sporting event in the area.

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Kentucky Center for the Performing Arts

8.8/10 (49 reviews)

Enjoy an outing to Kentucky Center for the Performing Arts during your stay in Louisville. Stroll along the riverfront or attend a sporting event in the area.

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Kentucky Museum of Art and Craft

You can spend an afternoon exploring the galleries in Kentucky Museum of Art and Craft during your trip to Louisville. Stroll along the area's riverfront or experience its lively festivals.

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Golden Statue of David

Find out about the history of Louisville when you spend time at Golden Statue of David. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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SAR Genealogical Research Library: NSSAR Library

You can spend time exploring the galleries in SAR Genealogical Research Library: NSSAR Library in Louisville. Amble around this family-friendly area's riverfront and enjoy its top-notch restaurants.

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Louisville Glassworks

You can spend an afternoon browsing the exhibits at Louisville Glassworks in Louisville. Experience the area's lively festivals or attend a sporting event.

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Frequently asked questions

What's the area like around Louisville Science Center?

Louisville Science Center is located in an area of Louisville known for its stunning river views, sporting events and great live music scene. If you're looking for a convenient place to stay, take a look at the 292 hotels and other accommodation options you'll find within a mile.

How many hotels can I expect to find close to Louisville Science Center?

Expedia has 292 hotels and other accommodation options within a mile from Louisville Science Center.

If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?

Yes! Most hotel room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the filter option "fully refundable" to get the top deals on offer near Louisville Science Center.

What can I see and do near Louisville Science Center?

21c Museum Hotel, Louisville Slugger Museum and Muhammad Ali Center feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Belle of Louisville, Whiskey Row and Big Four Bridge. You can catch a show at Louisville Palace, Derby Dinner Playhouse and Headliners Music Hall.

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Our top choices for Louisville Science Center hotels

1. Louisville Bourbon Inn

2. Market Street Inn

3. DuPont Mansion Bed & Breakfast

4. The Brown Hotel

5. Homewood Suites by Hilton Louisville Downtown, KY

6. Hotel Distil, Autograph Collection

7. Tempo By Hilton Louisville Downtown Nulu

8. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

9. Stellar Suites

10. The Grady

11. Towneplace Suites By Marriott Louisville Downtown

12. Aloft by Marriott Louisville Downtown

13. Hotel Genevieve part of JdV by Hyatt

14. Moxy Louisville Downtown

15. AC Hotel Louisville Downtown

16. Galt House Hotel Trademark Collection by Wyndham

17. Central Park Bed & Breakfast

18. Embassy Suites Louisville Downtown

19. Louisville Marriott Downtown

20. Holiday Inn Express & Suites Louisville Downtown by IHG

Compare popular hotels close to Louisville Science Center

Top Louisville Science Center Hotel Reviews

Holiday Inn Louisville Downtown by IHG

Embassy Suites Louisville Downtown

Holiday Inn Express & Suites Louisville Downtown by IHG

Radisson Hotel Louisville North

Homewood Suites by Hilton Louisville Downtown, KY

The Reserve on Main

Cambria Hotel Louisville Downtown-Whiskey Row

Hyatt Regency Louisville

Moxy Louisville Downtown

Other attractions near Louisville Science Center

Louisville Slugger Museum

Muhammad Ali Center

Frazier International History Museum

Kentucky Center for the Performing Arts

Kentucky Museum of Art and Craft

Golden Statue of David

SAR Genealogical Research Library: NSSAR Library

Louisville Glassworks

Frequently asked questions

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