The entrance to the Kentucky Science Center with a large circular structure in the foreground.

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Our top choices for Louisville Science Center hotels

1. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville, < 0.1 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,006 reviews)
"Excellent stay!"
United States
William
The price is 4.224.774 ₫
5.102.360 ₫ total
includes taxes & fees
19 Jul - 20 Jul
21c Museum Hotel Louisville

2. The Grady

The Grady
4.0 star property
Downtown Louisville, 0.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,003 reviews)
"We loved this hotel. It was clean, close to our activities and the staff was friendly."
United States
Elizabeth
The price is 4.122.211 ₫
4.850.194 ₫ total
includes taxes & fees
30 Jun - 1 Jul
The Grady

3. Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,953 reviews)
"Great stay!"
United States
Cortney
The price is 4.186.642 ₫
4.925.879 ₫ total
includes taxes & fees
1 Jul - 2 Jul
Omni Louisville Hotel

4. Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
Downtown Louisville, 0.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,009 reviews)
"The staff was super friendly and the location was perfect!"
United States
Lateshia
The price is 3.435.571 ₫
4.042.266 ₫ total
includes taxes & fees
5 Jul - 6 Jul
Homewood Suites by Hilton Louisville Downtown, KY

5. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.4 out of 10, Exceptional, (121 reviews)
"Great stay"
United States
Kristen
The price is 4.722.595 ₫
5.556.605 ₫ total
includes taxes & fees
5 Jul - 6 Jul
Hotel Bourré Bonne Louisville, Curio Collection by Hilton

6. The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville, 1.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,255 reviews)
"Nice staff, large room"
United States
Lisa
The price is 4.217.308 ₫
4.962.085 ₫ total
includes taxes & fees
1 Jul - 2 Jul
The Brown Hotel

7. Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
Downtown Louisville, 0.7 km from Louisville Science Center
8.8 out of 10, Excellent, (1,002 reviews)
"Great location and easy parking. The staff was very friendly as well."
United States
Thomas
The price is 3.723.797 ₫
4.381.419 ₫ total
includes taxes & fees
3 Jul - 4 Jul
Hyatt Regency Louisville

8. Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
8.6 out of 10, Excellent, (1,001 reviews)
"Loved everything about it! The building is absolutely beautiful, the staff were very helpful, everything was very clean and comfortable. We loved the free tour and all of the history. The breakfast buffet was delicious and well worth it. We would love to come back!"
United States
Kayla
The price is 4.088.813 ₫
4.810.897 ₫ total
includes taxes & fees
2 Jul - 3 Jul
Seelbach Hilton Louisville Downtown

9. Stellar Suites

Stellar Suites
4.5 star property
East Market District, 2.2 km from Louisville Science Center
9.6 out of 10, Exceptional, (137 reviews)
"Lovely stay . Great self-contained room with everything Nulu has to offer on your doorstep..1st night there was some live music going on at across the street at Taj bar which kept me awake , but apart from that little bump i cannot fault the room... they have lots more in the back further away from street so worth checking. Excellent stay and will def return if im back !!"
United Kingdom
Andy
The price is 2.665.599 ₫
4.467.544 ₫ total
includes taxes & fees
1 Jul - 2 Jul
Stellar Suites

10. Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.6 out of 10, Exceptional, (476 reviews)
"Love staying here when we are in Louisville. "
United States
Edward
The price is 5.530.995 ₫
6.507.770 ₫ total
includes taxes & fees
26 Jul - 27 Jul
Hotel Distil, Autograph Collection

11. Market Street Inn

Market Street Inn
3.5 star property
2.1 km from Louisville Science Center
9.8 out of 10, Exceptional, (121 reviews)
"Great place near quite a few shops and restaurants. Close enough to downtown. Breakfast was nice and everyone was very welcoming."
United States
Anissa
The price is 4.384.929 ₫
4.954.807 ₫ total
includes taxes & fees
30 Jun - 1 Jul
Market Street Inn

12. Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.0 out of 10, Wonderful, (1,000 reviews)
"Great location and friendly staff. Loved their bar and lobby area."
United States
Bikash
The price is 5.128.110 ₫
6.033.735 ₫ total
includes taxes & fees
5 Jul - 6 Jul
Louisville Marriott Downtown

13. Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
East Market District, 2.1 km from Louisville Science Center
9.2 out of 10, Wonderful, (1,102 reviews)
"Great place to stay and within walking distance of most things in the area."
United Kingdom
Debra
The price is 3.550.230 ₫
4.177.200 ₫ total
includes taxes & fees
5 Jul - 6 Jul
Hotel Genevieve part of JdV by Hyatt

14. Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu
3.5 star property
Phoenix Hill, 2.1 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,047 reviews)
"Excellent location and clean hotel!"
United States
Monica
The price is 3.213.090 ₫
3.780.522 ₫ total
includes taxes & fees
30 Jun - 1 Jul
Tempo By Hilton Louisville Downtown Nulu

15. Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 0.3 km from Louisville Science Center
9.2 out of 10, Wonderful, (654 reviews)
"Great place to stay! I would definitely stay here again!"
United States
Dana Jean
The price is 2.997.972 ₫
3.527.413 ₫ total
includes taxes & fees
2 Jul - 3 Jul
Towneplace Suites By Marriott Louisville Downtown

16. Hilton Garden Inn Louisville Downtown

Hilton Garden Inn Louisville Downtown
3.5 star property
Downtown Louisville, 1 km from Louisville Science Center
8.4 out of 10, Very good, (1,001 reviews)
"Location, clean room, staff"
United States
Elsie
The price is 2.644.790 ₫
3.111.860 ₫ total
includes taxes & fees
5 Jul - 6 Jul
Hilton Garden Inn Louisville Downtown

17. Holiday Inn Louisville Downtown by IHG

Holiday Inn Louisville Downtown by IHG
3.0 star property
Downtown Louisville, 1.1 km from Louisville Science Center
8.0 out of 10, Very good, (915 reviews)
"Excellent hotel! Highly recommended!"
United States
Binkeung
The price is 1.619.957 ₫
2.215.462 ₫ total
includes taxes & fees
27 Jul - 28 Jul
Holiday Inn Louisville Downtown by IHG

18. Moxy Louisville Downtown

Moxy Louisville Downtown
3.5 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.2 out of 10, Wonderful, (788 reviews)
"Great and fun spot! Enjoyed our one night here"
United States
Adam
The price is 2.971.674 ₫
3.496.472 ₫ total
includes taxes & fees
4 Jul - 5 Jul
Moxy Louisville Downtown

19. AC Hotel Louisville Downtown

AC Hotel Louisville Downtown
3.5 star property
East Market District, 2.1 km from Louisville Science Center
9.2 out of 10, Wonderful, (669 reviews)
"Perfect location"
United States
Jeffrey
The price is 2.631.904 ₫
3.096.698 ₫ total
includes taxes & fees
3 Jul - 4 Jul
AC Hotel Louisville Downtown

20. Central Park Bed & Breakfast

Central Park Bed & Breakfast
3.5 star property
Old Louisville, 3 km from Louisville Science Center
9.2 out of 10, Wonderful, (83 reviews)
"Great place to stay "
United States
Matthias
The price is 3.565.483 ₫
4.138.516 ₫ total
includes taxes & fees
6 Jul - 7 Jul
Central Park Bed & Breakfast
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Louisville Science Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Terrace/patio
Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
9.4
Exceptional
1,009 reviews
View
Lobby
The Grady
4.0 star property
9.4
Exceptional
1,003 reviews
View
Front of property
21c Museum Hotel Louisville
4.5 star property
9.4
Exceptional
1,006 reviews
View
3 bars/lounges, cocktail bar, lobby lounge
Omni Louisville Hotel
4.0 star property
9.4
Exceptional
1,953 reviews
View
Terrace/patio
Hotel Distil, Autograph Collection
4.0 star property
9.6
Exceptional
476 reviews
View

Top Louisville Science Center Hotel Reviews

Hotels near other Louisville Science Center attractions

Frequently asked questions

What's the area like around Louisville Science Center?
Louisville Science Center is located in an area of Louisville known for its stunning river views, sporting events and great live music scene. If you're looking for a convenient place to stay, take a look at the 261 hotels and other accommodation options you'll find within a mile.
How many hotels can I expect to find close to Louisville Science Center?
Expedia has 261 hotels and other accommodation options within a mile from Louisville Science Center.
If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?
Yes! Most hotel room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the filter option "fully refundable" to get the top deals on offer near Louisville Science Center.
What can I see and do near Louisville Science Center?
21c Museum Hotel, Louisville Slugger Museum and Muhammad Ali Center feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Belle of Louisville, Whiskey Row and Union Station. You can catch a show at Louisville Palace, Derby Dinner Playhouse and Headliners Music Hall.