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Our top choices for Louisville Science Center hotels

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville, < 0.1 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,001 reviews)
"Location and the staff was fabulous."
United States
Madeline
The price is 4.652.747 ₫
5.604.611 ₫ total
includes taxes & fees
6 Feb - 7 Feb
21c Museum Hotel Louisville

Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
Downtown Louisville, 0.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,002 reviews)
"Super nice staff, everything was perfect!"
United States
Robyn
The price is 3.082.250 ₫
3.626.577 ₫ total
includes taxes & fees
15 Feb - 16 Feb
Homewood Suites by Hilton Louisville Downtown, KY

Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.6 out of 10, Exceptional, (444 reviews)
"Exceptionally handsome hotel design, extraordinary restaurant and service, fantastic location. "
United States
Carol
The price is 5.434.418 ₫
6.394.412 ₫ total
includes taxes & fees
8 Feb - 9 Feb
Hotel Distil, Autograph Collection

The Grady

The Grady
4.0 star property
Downtown Louisville, 0.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,004 reviews)
"Property was very well taken care of and unique. Staff was friendly and helpful. Room was very nice and the price was great!"
United States
Erica
The price is 5.240.189 ₫
6.165.605 ₫ total
includes taxes & fees
19 Feb - 20 Feb
The Grady

Louisville Bourbon Inn

Louisville Bourbon Inn
5.0 star property
Old Louisville, 2.9 km from Louisville Science Center
10.0 out of 10, Exceptional, (21 reviews)
"Absolutely the best B&B we have ever stayed with."
United States
Roy
The price is 6.888.145 ₫
7.995.071 ₫ total
includes taxes & fees
19 Feb - 20 Feb
Louisville Bourbon Inn

Market Street Inn

Market Street Inn
3.5 star property
2.1 km from Louisville Science Center
9.8 out of 10, Exceptional, (120 reviews)
"Warm greeting by Carol who shared all the information and details about the property. SUPER charming and convenient location. Highly recommend."
United States
Kelly
The price is 4.815.463 ₫
5.441.634 ₫ total
includes taxes & fees
10 Feb - 11 Feb
Market Street Inn

DuPont Mansion Bed & Breakfast

DuPont Mansion Bed & Breakfast
3.0 star property
Old Louisville, 2.8 km from Louisville Science Center
9.8 out of 10, Exceptional, (100 reviews)
"Breakfast was wonderful, great place to stay!"
United States
Janie
The price is 3.712.580 ₫
4.309.192 ₫ total
includes taxes & fees
19 Feb - 20 Feb
DuPont Mansion Bed & Breakfast

The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville, 1.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,180 reviews)
"Fantastic place to stay in Louisville."
United States
Nathaniel
The Brown Hotel

Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
Downtown Louisville, 1.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,002 reviews)
"Great stay "
United States
Sarah
The price is 2.803.085 ₫
3.298.109 ₫ total
includes taxes & fees
28 Feb - 1 Mar
Cambria Hotel Louisville Downtown-Whiskey Row

Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 0.3 km from Louisville Science Center
9.2 out of 10, Wonderful, (536 reviews)
"The hotel is so clean and easy access to everything downtown."
United States
Erin
The price is 2.963.202 ₫
3.486.503 ₫ total
includes taxes & fees
19 Feb - 20 Feb
Towneplace Suites By Marriott Louisville Downtown

Stellar Suites

Stellar Suites
4.5 star property
East Market District, 2.2 km from Louisville Science Center
9.6 out of 10, Exceptional, (119 reviews)
"The check-in process was simple and easy, the room was spotless and had so many amenities. "
United States
Grace
The price is 3.066.914 ₫
4.917.420 ₫ total
includes taxes & fees
19 Feb - 20 Feb
Stellar Suites

Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu
3.5 star property
Phoenix Hill, 2.1 km from Louisville Science Center
9.4 out of 10, Exceptional, (905 reviews)
"Always a great place to stay."
United States
Christopher
The price is 2.858.243 ₫
3.363.007 ₫ total
includes taxes & fees
1 Mar - 2 Mar
Tempo By Hilton Louisville Downtown Nulu

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.2 out of 10, Wonderful, (1,774 reviews)
"Amazing stay! "
United States
Erin
The price is 5.385.958 ₫
6.337.118 ₫ total
includes taxes & fees
10 Feb - 11 Feb
Omni Louisville Hotel

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville, 0.5 km from Louisville Science Center
9.0 out of 10, Wonderful, (4,040 reviews)
"Great hotel"
United States
Lazaro
The price is 4.002.748 ₫
4.709.634 ₫ total
includes taxes & fees
17 Feb - 18 Feb
Galt House Hotel Trademark Collection by Wyndham

Moxy Louisville Downtown

Moxy Louisville Downtown
3.5 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.2 out of 10, Wonderful, (714 reviews)
"First time trying a moxy, will be staying with moxy hotels from now on"
United States
Robinson
The price is 2.911.216 ₫
3.425.336 ₫ total
includes taxes & fees
8 Mar - 9 Mar
Moxy Louisville Downtown

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.2 out of 10, Wonderful, (70 reviews)
"i love this place"
United States
THANH
The price is 4.456.223 ₫
5.243.192 ₫ total
includes taxes & fees
22 Feb - 23 Feb
Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG
2.5 star property
Downtown Louisville, 0.2 km from Louisville Science Center
8.8 out of 10, Excellent, (1,694 reviews)
"Room was clean and the beds were very comfortable. Would definitely stay here again."
United States
Talva
The price is 2.132.164 ₫
2.508.705 ₫ total
includes taxes & fees
8 Feb - 9 Feb
Holiday Inn Express & Suites Louisville Downtown by IHG

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.0 out of 10, Wonderful, (1,149 reviews)
"Great room and breakfast. Close to several nice restaurants."
United States
Crystal
The price is 3.176.924 ₫
3.737.968 ₫ total
includes taxes & fees
15 Feb - 16 Feb
Embassy Suites Louisville Downtown

Aloft Louisville Downtown

Aloft Louisville Downtown
3.0 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.0 out of 10, Wonderful, (1,000 reviews)
"Great staff, good bar. "
United States
Edward
The price is 2.709.770 ₫
3.188.316 ₫ total
includes taxes & fees
8 Mar - 9 Mar
Aloft Louisville Downtown

Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
East Market District, 2.1 km from Louisville Science Center
9.2 out of 10, Wonderful, (1,034 reviews)
"Spotless room and courteous staff "
United States
Mary
The price is 3.252.850 ₫
3.827.302 ₫ total
includes taxes & fees
8 Feb - 9 Feb
Hotel Genevieve part of JdV by Hyatt
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Louisville Science Center Hotel Reviews

Hotels near other Louisville Science Center attractions

Frequently asked questions

What's the area like around Louisville Science Center?
Louisville Science Center is located in an area of Louisville known for its stunning river views, sporting events and great live music scene. If you're looking for a convenient place to stay, take a look at the 308 hotels and other accommodation options you'll find within a mile.
How many hotels can I expect to find close to Louisville Science Center?
Expedia has 308 hotels and other accommodation options within a mile from Louisville Science Center.
If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?
Yes! Most hotel room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the filter option "fully refundable" to get the top deals on offer near Louisville Science Center.
What can I see and do near Louisville Science Center?
21c Museum Hotel, Louisville Slugger Museum and Muhammad Ali Center feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Belle of Louisville, Whiskey Row and Thomas Edison House. You can catch a show at Kentucky Center for the Performing Arts, Louisville Palace and Derby Dinner Playhouse.