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Search Hotels in Mission Bay, San Francisco

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Check prices for these dates

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19 Dec - 20 Dec
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20 Dec - 21 Dec
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19 Dec - 21 Dec
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26 Dec - 28 Dec

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Our top choices for Mission Bay hotels

Tapas bar
LUMA Hotel San Francisco

LUMA Hotel San Francisco

LUMA Hotel San Francisco
4.0 star property
Mission Bay
9.6 out of 10, Exceptional, (2381)
"Clean, good location, and walkable things to do"
United States
Landry
The price is 5.131.425 ₫
6.039.431 ₫ total
includes taxes & fees
21 Dec - 22 Dec
LUMA Hotel San Francisco
Lobby
Hilton San Francisco Financial District

Hilton San Francisco Financial District

Hilton San Francisco Financial District
4.0 star property
Financial District, 3 km from Mission Bay
8.6 out of 10, Excellent, (2151)
"Great hotel "
United States
Tanya
The price is 2.819.915 ₫
3.318.899 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Hilton San Francisco Financial District
Lobby sitting area
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf
4.0 star property
Fisherman's Wharf, 4.5 km from Mission Bay
9.0 out of 10, Wonderful, (7202)
"Great stay"
United States
Isaac
The price is 2.828.121 ₫
4.412.736 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hotel Riu Plaza Fisherman's Wharf
Breakfast and dinner served
DoubleTree by Hilton San Francisco Airport North Bayfront

DoubleTree by Hilton San Francisco Airport North Bayfront

DoubleTree by Hilton San Francisco Airport North Bayfront
4.0 star property
10.8 km from Mission Bay
8.0 out of 10, Very good, (1321)
"Great location, clean and comfortable beds "
United States
Rubia
The price is 2.136.252 ₫
2.527.618 ₫ total
includes taxes & fees
22 Dec - 23 Dec
DoubleTree by Hilton San Francisco Airport North Bayfront
Terrace/patio
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco
4.0 star property
Financial District, 2.8 km from Mission Bay
8.8 out of 10, Excellent, (2812)
"Clean and comfortable room, good staff, great location. "
United Kingdom
David
The price is 2.639.771 ₫
3.107.022 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Club Quarters Hotel in San Francisco
Property amenity
Holiday Inn Express and Suites Fisherman's Wharf by IHG

Holiday Inn Express and Suites Fisherman's Wharf by IHG

Holiday Inn Express and Suites Fisherman's Wharf by IHG
3.0 star property
Fisherman's Wharf, 4.5 km from Mission Bay
9.2 out of 10, Wonderful, (2223)
"Hotel is so nice, the room is so clean, the staff is so nice."
United States
Griselda
The price is 3.132.556 ₫
4.476.581 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express and Suites Fisherman's Wharf by IHG
Lobby sitting area
Chancellor Hotel on Union Square

Chancellor Hotel on Union Square

Chancellor Hotel on Union Square
3.5 star property
2.5 km from Mission Bay
9.4 out of 10, Exceptional, (3081)
"Great hotel, great location, super friendly all staff "
Mexico
Claudia
The price is 1.993.778 ₫
2.355.851 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Chancellor Hotel on Union Square
Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds
Hotel Caza Fisherman's Wharf

Hotel Caza Fisherman's Wharf

Hotel Caza Fisherman's Wharf
4.0 star property
Fisherman's Wharf, 4.6 km from Mission Bay
9.0 out of 10, Wonderful, (3835)
"Excellent stay and great location! "
United States
CHRISTINE
The price is 3.198.366 ₫
4.972.604 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Hotel Caza Fisherman's Wharf
Lounge
King George Hotel

King George Hotel

King George Hotel
3.0 star property
2.4 km from Mission Bay
8.6 out of 10, Excellent, (2107)
"Great place!"
United States
Troy
The price is 2.249.406 ₫
3.042.277 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
King George Hotel
Exterior
Handlery Union Square Hotel

Handlery Union Square Hotel

Handlery Union Square Hotel
3.5 star property
Union Square, 2.4 km from Mission Bay
8.8 out of 10, Excellent, (2790)
"Clean hotel, great location, kind staff! "
United States
Felix
The price is 27.611.014 ₫
32.496.782 ₫ total
includes taxes & fees
14 Jan - 15 Jan 2026
Handlery Union Square Hotel
Exterior
The Westin San Francisco Airport

The Westin San Francisco Airport

The Westin San Francisco Airport
4.0 star property
18.6 km from Mission Bay
8.8 out of 10, Excellent, (2023)
"Comfortable room, welcome glass of wine, easy shuttle to and from airport, friendly staff."
United States
Carole
The price is 2.708.340 ₫
3.883.392 ₫ total
includes taxes & fees
22 Dec - 23 Dec
The Westin San Francisco Airport
Courtyard
Hilton San Francisco Airport Bayfront

Hilton San Francisco Airport Bayfront

Hilton San Francisco Airport Bayfront
4.0 star property
20.5 km from Mission Bay
8.6 out of 10, Excellent, (2743)
"Nice airport hotel…staff was great, breakfast was amazing "
United States
Lynne
The price is 2.460.768 ₫
2.797.770 ₫ total
includes taxes & fees
30 Dec - 31 Dec
Hilton San Francisco Airport Bayfront
Hypo-allergenic bedding, in-room safe, desk, laptop workspace
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG
3.5 star property
Nob Hill, 3.4 km from Mission Bay
9.0 out of 10, Wonderful, (5006)
"Rooms were great, staff was great, location was great. "
United States
Jonathan
The price is 3.131.485 ₫
3.685.602 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Holiday Inn Golden Gateway by IHG
Breakfast, lunch, dinner served; local cuisine
DoubleTree by Hilton San Francisco Airport

DoubleTree by Hilton San Francisco Airport

DoubleTree by Hilton San Francisco Airport
4.0 star property
20.3 km from Mission Bay
8.6 out of 10, Excellent, (1365)
"Nice hotel and area "
Canada
Robert
The price is 2.783.601 ₫
3.164.816 ₫ total
includes taxes & fees
28 Dec - 29 Dec
DoubleTree by Hilton San Francisco Airport
Daily buffet breakfast (USD 22 per person)
citizenM San Francisco Union Square

citizenM San Francisco Union Square

citizenM San Francisco Union Square
4.0 star property
Union Square, 2.2 km from Mission Bay
9.4 out of 10, Exceptional, (1426)
"Great location."
United States
Todd
The price is 2.662.673 ₫
3.133.832 ₫ total
includes taxes & fees
24 Dec - 25 Dec
citizenM San Francisco Union Square
Indoor pool
Hotel Nikko San Francisco

Hotel Nikko San Francisco

Hotel Nikko San Francisco
4.5 star property
Union Square, 2.3 km from Mission Bay
9.4 out of 10, Exceptional, (2650)
"Clean rooms, great location and welcoming staff"
United Kingdom
Simon
The price is 4.005.197 ₫
5.924.217 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hotel Nikko San Francisco
Property entrance
Orchard Garden Hotel

Orchard Garden Hotel

Orchard Garden Hotel
4.0 star property
Chinatown, 2.6 km from Mission Bay
9.6 out of 10, Exceptional, (1003)
"Great location "
Canada
Jorge
The price is 3.530.048 ₫
4.213.617 ₫ total
includes taxes & fees
7 Jan - 8 Jan 2026
Orchard Garden Hotel
Courtyard
Hotel Zephyr San Francisco

Hotel Zephyr San Francisco

Hotel Zephyr San Francisco
4.0 star property
Fisherman's Wharf, 4.5 km from Mission Bay
8.6 out of 10, Excellent, (2332)
"Great decor and really great location"
United States
Jose
The price is 3.515.833 ₫
5.067.459 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Hotel Zephyr San Francisco
Exterior
InterContinental San Francisco by IHG

InterContinental San Francisco by IHG

InterContinental San Francisco by IHG
4.0 star property
South of Market, 1.7 km from Mission Bay
9.2 out of 10, Wonderful, (1026)
"Love this hotel in SF."
United States
JONATHAN
The price is 4.106.544 ₫
5.917.747 ₫ total
includes taxes & fees
23 Dec - 24 Dec
InterContinental San Francisco by IHG
Bar (on property)
Hyatt Centric Fisherman's Wharf San Francisco

Hyatt Centric Fisherman's Wharf San Francisco

Hyatt Centric Fisherman's Wharf San Francisco
4.0 star property
Fisherman's Wharf, 4.5 km from Mission Bay
8.6 out of 10, Excellent, (1469)
"Not so special but nice place to stay "
United States
Claire
The price is 3.448.444 ₫
5.142.932 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Hyatt Centric Fisherman's Wharf San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Mission Bay

Find the best Mission Bay areas for the activities you enjoy most.
Union Square featuring a skyscraper and a city

Union Square

Known for its charming cafes and popular shops, there's plenty to explore in Union Square. Check out top attractions like Westin St Francis Hotel Glass Elevators and Union Square, and jump on the metro at Powell St & Geary Blvd Stop or Powell St & Post St Stop to see more of the city.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and San Francisco Bay are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

Fisherman\'s Wharf featuring a bay or harbour

Fisherman's Wharf

Travellers love Fisherman's Wharf for its popular shops, and you can see more of San Francisco by jumping on the metro at Jones St and Beach St Stop or Jefferson St & Taylor St Stop. You might spend time checking out top sights like Pier 39 and San Francisco Bay.

South of Market which includes skyline, a park and cbd

South of Market

Gourmet restaurants great entertainment and top sights from Oracle Park to San Francisco Bay – discover South of Market, a destination also famous for its shopping.

Nob Hill showing street scenes and a city

Nob Hill

Gourmet restaurants Chinatown and top sights from SF Masonic Auditorium to Cable Car Museum – discover Nob Hill, a destination also famous for its shopping.

Top Mission Bay Hotel Reviews

Frequently asked questions

What is Mission Bay like?
Travellers will be sure to enjoy their time in San Francisco's Mission Bay neighbourhood. Make sure that you visit Chase Center and Lefty O'Doul Bridge as part of your Mission Bay travel plans.
How many hotels will I be able to find in Mission Bay?
When you want to put your feet up after a day of exploring the sights in San Francisco, you can choose from 18 Expedia hotels and other accommodation options in Mission Bay.
If I need to cancel my hotel reservation in Mission Bay, will I receive a refund?
Yes! The majority of hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to review the best deals available in Mission Bay.
What are the top things to see and do in Mission Bay?
Chase Center, Lefty O'Doul Bridge and Lucky Strike San Francisco are just a few attractions to check out in Mission Bay. While you're out sightseeing, Oracle Park and Pier 39 are a couple of additional sights to visit in San Francisco.
How can I get around Mission Bay and the greater San Francisco area?
For a quick way to explore the city, catch a ride on metro transit at UCSF/Chase Center Stop, Mission Rock Station or UCSF Mission Bay Stop. To venture out of town, take a train from San Francisco Station.