What is Mission Bay like?

Travellers will be sure to enjoy their time in San Francisco's Mission Bay neighbourhood. Looking for sights you might find in a travel guide about Mission Bay? Consider a visit to Chase Center while you're in the neighbourhood.

How many hotels will I be able to find in Mission Bay?

When you want to find places to stay in San Francisco, start by booking one of Expedia's 5 hotels and other accommodation options in Mission Bay.

If I need to cancel my hotel reservation in Mission Bay, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to review the best deals available in Mission Bay.

What are the top things to see and do in Mission Bay?

Chase Center, PIER 48 - Lot #39 and Lefty O'Doul Bridge are just a few attractions to check out in Mission Bay. A visit to Lucky Strike San Francisco is also worth the trip while you're discovering the neighbourhood. Oracle Park and Pier 39 are some popular places to visit in the area around Mission Bay. When you're sightseeing in San Francisco, Bottom of the Hill and California College of the Arts are also worth a stop.

How can I get around Mission Bay and the greater San Francisco area?

For a quick way to explore the city, catch a ride on metro transit at Mission Rock Station, UCSF/Chase Center Stop or UCSF Mission Bay Stop. To venture out of town, take a train from San Francisco Station.

The Best Hotels in Mission Bay, San Francisco - 2026 Updated Prices

A coastal cityscape with a large body of water, several ships, and ongoing construction on a prominent red building.

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Our top choices for Mission Bay hotels

1. LUMA Hotel San Francisco

Mission Bay

Fernando

7.221.765 ₫ total

includes taxes & fees

22 Aug - 23 Aug

2. Hyatt Place San Francisco Downtown

0.9 km from Mission Bay

angelica

6.514.795 ₫ total

includes taxes & fees

5 Sept - 6 Sept

Hypo-allergenic bedding, in-room safe, desk, laptop workspace

3. Holiday Inn Golden Gateway by IHG

Nob Hill, 3.4 km from Mission Bay

Sampada

4.675.730 ₫ total

includes taxes & fees

31 Aug - 1 Sept

4. Hotel Nikko San Francisco

Union Square, 2.3 km from Mission Bay

Joseph

6.659.822 ₫ total

includes taxes & fees

6 Sept - 7 Sept

5. Handlery Union Square Hotel

Union Square, 2.4 km from Mission Bay

Katherine

5.047.430 ₫ total

includes taxes & fees

16 Aug - 17 Aug

6. Galleria Park Hotel

Financial District, 2.4 km from Mission Bay

LOVLEEN

4.935.487 ₫ total

includes taxes & fees

16 Aug - 17 Aug

7. Hotel Riu Plaza Fisherman's Wharf

Fisherman's Wharf, 4.5 km from Mission Bay

Sadonya

5.122.537 ₫ total

includes taxes & fees

31 Aug - 1 Sept

8. Stanford Court San Francisco

Nob Hill, 2.8 km from Mission Bay

Steven

5.133.936 ₫ total

includes taxes & fees

31 Aug - 1 Sept

9. Club Quarters Hotel Embarcadero, San Francisco

Financial District, 2.8 km from Mission Bay

Nadya

4.446.533 ₫ total

includes taxes & fees

16 Aug - 17 Aug

10. The Pickwick Hotel

South of Market, 1.9 km from Mission Bay

Marcus

2.881.111 ₫ total

includes taxes & fees

18 Aug - 19 Aug

2 bars/lounges, rooftop bar, lobby lounge

11. Hilton San Francisco Union Square

Union Square, 2.4 km from Mission Bay

Sarah

4.515.066 ₫ total

includes taxes & fees

3 Sept - 4 Sept

12. The Marker Union Square San Francisco

Theater District, 2.5 km from Mission Bay

Jacquelyn

4.769.936 ₫ total

includes taxes & fees

23 Aug - 24 Aug

13. Hyatt Regency San Francisco

Financial District, 2.6 km from Mission Bay

Saul

8.237.223 ₫ total

includes taxes & fees

14 Aug - 15 Aug

14. Chancellor Hotel on Union Square

Lower Nob Hill, 2.5 km from Mission Bay

Padre

2.936.641 ₫ total

includes taxes & fees

23 Aug - 24 Aug

15. Grand Hyatt San Francisco

Union Square, 2.5 km from Mission Bay

Esteban

5.629.272 ₫ total

includes taxes & fees

6 Sept - 7 Sept

16. King George Hotel

Union Square, 2.4 km from Mission Bay

Carol M

3.180.573 ₫ total

includes taxes & fees

17 Aug - 18 Aug

17. Hotel Zelos San Francisco

South of Market, 2 km from Mission Bay

Denise

6.453.524 ₫ total

includes taxes & fees

16 Aug - 17 Aug

18. YOTEL San Francisco

2.1 km from Mission Bay

Daniel

3.687.536 ₫ total

includes taxes & fees

23 Aug - 24 Aug

19. Hotel Fusion

Union Square, 2.2 km from Mission Bay

Shamla

3.378.452 ₫ total

includes taxes & fees

16 Aug - 17 Aug

20. Executive Hotel Vintage Court

Chinatown, 2.6 km from Mission Bay

Kasey

4.018.983 ₫ total

includes taxes & fees

14 Aug - 15 Aug

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Where to stay in Mission Bay

Find the best Mission Bay areas for the activities you enjoy most.

A street with shops, including a crystal shop and a crepes cafe.

Fisherman's Wharf

Travellers love Fisherman's Wharf for its popular shops, and you can see more of San Francisco by jumping on the metro at Jones St and Beach St Stop or Jefferson St & Taylor St Stop. You might spend time checking out top sights like Pier 39 and San Francisco Bay.

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A cityscape with tall buildings, a central plaza with palm trees, and a flag on one of the buildings.

Union Square

Known for its charming cafes and popular shops, there's plenty to explore in Union Square. Check out top attractions like Westin St Francis Hotel Glass Elevators and Union Square, and jump on the metro at Powell St & Geary Blvd Stop or Powell St & Post St Stop to see more of the city.

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A trolley on a street with buildings and a clock tower.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and Chase Center are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

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A cityscape with modern skyscrapers, a central park with pathways, and a few people walking.

South of Market

Gourmet restaurants great entertainment and top sights from Oracle Park to Chase Center – discover South of Market, a destination also famous for its shopping.

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A street lined with historic buildings, parked cars, and a clear blue sky.

Nob Hill

Gourmet restaurants Chinatown and top sights from SF Masonic Auditorium to Cable Car Museum – discover Nob Hill, a destination also famous for its shopping.

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Top Mission Bay Hotel Reviews

Club Quarters Hotel in San Francisco

8/10 Good

"Z"

Marriott Vacation Club®, San Francisco

10/10 Excellent

"Great location near fisherman’s wharf. We got there earlier than check in so they took care of our bags while we explored the city. Room was clean and comfortable. No kitchen/breakfast on site but the water station with lots of flavors was a nice touch. The kids enjoyed the sorbet tasting on Tuesday afternoon. The valet let us park our rented e-bikes in the garage since he said not to leave them unattended even locked in the neighborhood. We enjoyed this hotel and we would definitely stay here again."

Hotel Julian

8/10 Good

"Nice hotel with a lot of history for movie fans and tourists. Very walkable area and close to the BART if needed. Front desk staff need some work in customer service. The Food and Beverage department makes this place. Michael at the bar, along with the breakfast team go above and beyond to make you feel welcome and a guest at the property."

Chancellor Hotel on Union Square

10/10 Excellent

"This is a hidden gem! We were somewhat leery booking this property because the price was $150 for the night. What we experienced was a great boutique style hotel. The room was smaller but had a large walk in closet, which you don’t see in hotels. This allowed us to put luggage in there and made the room feel bigger. Highly recommend staying here!"

Search Hotels in Mission Bay, San Francisco

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Our top choices for Mission Bay hotels

1. LUMA Hotel San Francisco

2. Hyatt Place San Francisco Downtown

3. Holiday Inn Golden Gateway by IHG

4. Hotel Nikko San Francisco

5. Handlery Union Square Hotel

6. Galleria Park Hotel

7. Hotel Riu Plaza Fisherman's Wharf

8. Stanford Court San Francisco

9. Club Quarters Hotel Embarcadero, San Francisco

10. The Pickwick Hotel

11. Hilton San Francisco Union Square

12. The Marker Union Square San Francisco

13. Hyatt Regency San Francisco

14. Chancellor Hotel on Union Square

15. Grand Hyatt San Francisco

16. King George Hotel

17. Hotel Zelos San Francisco

18. YOTEL San Francisco

19. Hotel Fusion

20. Executive Hotel Vintage Court

Where to stay in Mission Bay

Fisherman's Wharf

Union Square

Downtown San Francisco

South of Market

Nob Hill

Top Mission Bay Hotel Reviews

Club Quarters Hotel in San Francisco

Frequently asked questions

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