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Search Hotels in Mission Bay, San Francisco

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Our top choices for Mission Bay hotels

LUMA Hotel San Francisco

LUMA Hotel San Francisco
4.0 star property
Mission Bay
9.6 out of 10, Exceptional, (2362)
"Excellent location and room was spacious, clean and very comfortable bed. We will definitely stay here again! Great, friendly staff was an added bonus! "
United States
Linda
The price is 5.139.615 ₫
6.049.195 ₫ total
includes taxes & fees
21 Dec - 22 Dec
LUMA Hotel San Francisco

Hilton San Francisco Financial District

Hilton San Francisco Financial District
4.0 star property
Financial District, 3 km from Mission Bay
8.6 out of 10, Excellent, (2114)
"Great stay "
United States
Samantha
The price is 2.463.852 ₫
2.899.830 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hilton San Francisco Financial District

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf
4.0 star property
Fisherman's Wharf, 4.5 km from Mission Bay
9.0 out of 10, Wonderful, (7180)
"Good location and great hotel to stay, the bed was very comfortable and the breakfast was good with lots of options! "
Canada
Veronica
The price is 3.227.582 ₫
4.884.611 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Hotel Riu Plaza Fisherman's Wharf

King George Hotel

King George Hotel
3.0 star property
2.4 km from Mission Bay
8.6 out of 10, Excellent, (2101)
"What a wonderful stay completely recommend Daya was amazing"
United States
Glenda
The price is 2.252.996 ₫
3.047.132 ₫ total
includes taxes & fees
18 Dec - 19 Dec
King George Hotel

Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco
4.0 star property
Financial District, 2.8 km from Mission Bay
8.8 out of 10, Excellent, (2795)
"Clean and comfortable room, good staff, great location. "
United Kingdom
David
The price is 2.643.080 ₫
3.110.773 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Club Quarters Hotel in San Francisco

Chancellor Hotel on Union Square

Chancellor Hotel on Union Square
3.5 star property
2.5 km from Mission Bay
9.4 out of 10, Exceptional, (3057)
"Best location, friendly staff, had a wonderful time stayed! "
United States
Kalinda
The price is 1.996.278 ₫
2.358.805 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Chancellor Hotel on Union Square

Holiday Inn Express and Suites Fisherman's Wharf by IHG

Holiday Inn Express and Suites Fisherman's Wharf by IHG
3.0 star property
Fisherman's Wharf, 4.5 km from Mission Bay
9.2 out of 10, Wonderful, (2216)
"spotless, breakfast, location, all excellent I will come back!"
United States
Oscar
The price is 3.136.483 ₫
4.482.271 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express and Suites Fisherman's Wharf by IHG

DoubleTree by Hilton San Francisco Airport

DoubleTree by Hilton San Francisco Airport
4.0 star property
20.3 km from Mission Bay
8.6 out of 10, Excellent, (1357)
"Nice hotel and area "
Canada
Robert
The price is 2.442.240 ₫
2.776.705 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
DoubleTree by Hilton San Francisco Airport

Hotel Caza Fisherman's Wharf

Hotel Caza Fisherman's Wharf
4.0 star property
Fisherman's Wharf, 4.6 km from Mission Bay
9.0 out of 10, Wonderful, (3826)
"We stay here a lot, great place and safe."
United States
Albert
The price is 3.060.048 ₫
4.811.207 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Hotel Caza Fisherman's Wharf

Hotel Nikko San Francisco

Hotel Nikko San Francisco
4.5 star property
Union Square, 2.3 km from Mission Bay
9.4 out of 10, Exceptional, (2632)
"The entire hotel was fabulous!"
United States
Nicole
The price is 4.010.218 ₫
5.931.643 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hotel Nikko San Francisco

Hilton San Francisco Airport Bayfront

Hilton San Francisco Airport Bayfront
4.0 star property
20.5 km from Mission Bay
8.6 out of 10, Excellent, (2724)
"Nice airport hotel…staff was great, breakfast was amazing "
United States
Lynne
The price is 2.463.852 ₫
2.801.277 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hilton San Francisco Airport Bayfront

Hotel Zoe Fisherman's Wharf

Hotel Zoe Fisherman's Wharf
4.0 star property
Fisherman's Wharf, 4.5 km from Mission Bay
9.2 out of 10, Wonderful, (1606)
"Great location and awesome hotel"
United States
Adam
The price is 3.060.048 ₫
4.721.857 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Hotel Zoe Fisherman's Wharf

InterContinental San Francisco by IHG

InterContinental San Francisco by IHG
4.0 star property
South of Market, 1.7 km from Mission Bay
9.2 out of 10, Wonderful, (1020)
"Beautiful room and excellent food!"
United States
Melissa
The price is 3.874.479 ₫
5.646.196 ₫ total
includes taxes & fees
22 Dec - 23 Dec
InterContinental San Francisco by IHG

Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG
3.5 star property
Nob Hill, 3.4 km from Mission Bay
9.0 out of 10, Wonderful, (4954)
"Rooms were great, staff was great, location was great. "
United States
Jonathan
The price is 3.136.483 ₫
3.691.483 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Holiday Inn Golden Gateway by IHG

Hotel Shattuck Plaza

Hotel Shattuck Plaza
4.0 star property
15.4 km from Mission Bay
8.8 out of 10, Excellent, (1078)
"Wonderful, will stay here again."
United States
Jennifer
Hotel Shattuck Plaza

The Marina Inn on San Francisco Bay

The Marina Inn on San Francisco Bay
2.5 star property
19.6 km from Mission Bay
8.6 out of 10, Excellent, (2284)
"Great place to stay!"
United States
Dixon
The Marina Inn on San Francisco Bay

citizenM San Francisco Union Square

citizenM San Francisco Union Square
4.0 star property
Union Square, 2.2 km from Mission Bay
9.4 out of 10, Exceptional, (1423)
"Great location."
United States
Todd
The price is 2.820.199 ₫
3.319.233 ₫ total
includes taxes & fees
24 Dec - 25 Dec
citizenM San Francisco Union Square

DoubleTree by Hilton Hotel Berkeley Marina

DoubleTree by Hilton Hotel Berkeley Marina
4.0 star property
12.9 km from Mission Bay
8.2 out of 10, Very good, (3911)
"Great place to stay!"
United States
Rafael
The price is 3.131.212 ₫
3.607.000 ₫ total
includes taxes & fees
18 Dec - 19 Dec
DoubleTree by Hilton Hotel Berkeley Marina

Galleria Park Hotel

Galleria Park Hotel
4.0 star property
Financial District, 2.4 km from Mission Bay
9.6 out of 10, Exceptional, (1004)
"I had a great stay. The room was nice, the bed was comfortable, and the staff were very helpful."
United States
Luke
The price is 3.102.482 ₫
4.737.111 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Galleria Park Hotel

Stanford Court San Francisco

Stanford Court San Francisco
4.0 star property
Nob Hill, 2.9 km from Mission Bay
9.0 out of 10, Wonderful, (1335)
"Great room, great view, always clean"
United States
Edward
The price is 3.407.565 ₫
5.189.482 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Stanford Court San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Mission Bay

Find the best Mission Bay areas for the activities you enjoy most.

Union Square

Known for its charming cafes and popular shops, there's plenty to explore in Union Square. Check out top attractions like Westin St Francis Hotel Glass Elevators and Union Square, and jump on the metro at Powell St & Geary Blvd Stop or Powell St & Post St Stop to see more of the city.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and Chase Center are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

Fisherman's Wharf

Travellers love Fisherman's Wharf for its popular shops, and you can see more of San Francisco by jumping on the metro at Jones St and Beach St Stop or Jefferson St & Taylor St Stop. You might spend time checking out top sights like Pier 39 and Hyde Street Pier.

South of Market

Gourmet restaurants great entertainment and top sights from Oracle Park to Chase Center – discover South of Market, a destination also famous for its shopping.

Nob Hill

Gourmet restaurants Chinatown and top sights from SF Masonic Auditorium to Cable Car Museum – discover Nob Hill, a destination also famous for its shopping.

Top Mission Bay Hotel Reviews

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Frequently asked questions

What is Mission Bay like?
Travellers will be sure to enjoy their time in San Francisco's Mission Bay neighbourhood. Looking for sights you might find in a travel guide about Mission Bay? Consider a visit to Chase Center while you're in the neighbourhood.
How many hotels will I be able to find in Mission Bay?
When you want to put your feet up after a day of exploring the sights in San Francisco, you can choose from 17 Expedia hotels and other accommodation options in Mission Bay.
If I need to cancel my hotel reservation in Mission Bay, will I receive a refund?
Yes! The majority of hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to review the best deals available in Mission Bay.
What are the top things to see and do in Mission Bay?
Chase Center, Lucky Strike San Francisco and Lefty O'Doul Bridge are just a few attractions to check out in Mission Bay. While you're out sightseeing, Oracle Park and Pier 39 are a couple of additional sights to visit in San Francisco.
How can I get around Mission Bay and the greater San Francisco area?
For a quick way to explore the city, catch a ride on metro transit at UCSF/Chase Center Stop, Mission Rock Station or UCSF Mission Bay Stop. To venture out of town, take a train from San Francisco Station.