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Check availability on Mission Valley Luxury Hotels

Our top choices for Mission Valley luxury hotels

Exterior
Best Western Seven Seas

Best Western Seven Seas

Best Western Seven Seas
3.0 star property
Mission Valley
7.8 out of 10, Good, (3044)
"Very clean hotel and the people that cleans are really nice. Perfect to visit San Diego, great location."
United States
Ernesto Alonso
The price is 1.953.317 ₫
2.245.240 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Best Western Seven Seas
Lobby sitting area
Kings Inn San Diego

Kings Inn San Diego

Kings Inn San Diego
2.5 star property
Mission Valley
8.8 out of 10, Excellent, (3562)
"Room was very clean, and the breakfast was good"
United States
Roxana
The price is 1.973.217 ₫
2.264.266 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Kings Inn San Diego
Outdoor pool, a heated pool
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle
3.0 star property
Mission Valley
8.0 out of 10, Very good, (2431)
"All was very nice. "
United States
Milton
The price is 2.329.959 ₫
2.678.171 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Days Inn by Wyndham San Diego Hotel Circle
View from property
The Atwood Hotel San Diego - SeaWorld/Zoo

The Atwood Hotel San Diego - SeaWorld/Zoo

The Atwood Hotel San Diego - SeaWorld/Zoo
3.0 star property
Mission Valley
8.0 out of 10, Very good, (1814)
"Clean and helpful staff, thank you !"
United States
Bora
The Atwood Hotel San Diego - SeaWorld/Zoo
Basic Room, 2 Queen Beds, Non Smoking | Desk, iron/ironing board, free WiFi, bed sheets
Super 8 by Wyndham San Diego Hotel Circle

Super 8 by Wyndham San Diego Hotel Circle

Super 8 by Wyndham San Diego Hotel Circle
2.0 star property
Mission Valley
7.2 out of 10, Good, (619)
"Clean room nice area I had a pleasant stay!"
United States
Hector
The price is 2.217.942 ₫
2.549.414 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Super 8 by Wyndham San Diego Hotel Circle
Outdoor pool
Motel 6 San Diego, CA - Hotel Circle - Mission Valley

Motel 6 San Diego, CA - Hotel Circle - Mission Valley

Motel 6 San Diego, CA - Hotel Circle - Mission Valley
2.0 star property
Mission Valley
6.8 out of 10, (1479)
"Great location but the hotel needs a deep cleaning. "
United States
Michael
The price is 1.924.852 ₫
2.213.988 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Motel 6 San Diego, CA - Hotel Circle - Mission Valley
Outdoor pool
Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel
4.0 star property
Mission Valley
8.6 out of 10, Excellent, (1651)
"Decent room, great staff and close to am"
United States
siva
The price is 3.110.126 ₫
3.574.934 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Sheraton Mission Valley San Diego Hotel
Exterior
Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley
2.5 star property
Mission Valley
8.8 out of 10, Excellent, (1275)
"Room was clean,buffet bkfast was good,staff were friendly & helpful!"
United States
Barry
The price is 2.572.443 ₫
2.956.896 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn San Diego/Mission Valley
Exterior
E-Z 8 Motel Old Town

E-Z 8 Motel Old Town

E-Z 8 Motel Old Town
2.5 star property
Old Town San Diego
6.4 out of 10, (2076)
"Great staff, great room, great stay, great price!!!"
United States
Breanna
The price is 1.478.628 ₫
1.699.500 ₫ total
includes taxes & fees
14 Dec - 15 Dec
E-Z 8 Motel Old Town
Room, 2 Queen Beds (Trendy, Firepit) | Lobby
Town and Country San Diego

Town and Country San Diego

Town and Country San Diego
4.0 star property
Mission Valley
8.6 out of 10, Excellent, (1322)
"Clean room, friendly staff."
United States
Gail
The price is 3.786.183 ₫
5.261.607 ₫ total
includes taxes & fees
12 Dec - 13 Dec
Town and Country San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mission Valley Hotel Reviews

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

10/10 Excellent
"The room was pretty great there was a nice view of the town, but we could see homeless people in tents sleeping, so there was that. Front desk was amazing. The bar downstairs was great my husband went down and had a drink and watched some sports. Overall a great trip: for a three-star hotel, it was fantastic! Price of room was average, but the parking was a little much at $37.50 for one 24 hour peri[parking fr 9:00 p.m. to 5:00 a.m. was steep."
Jennifer 1-night trip
Posted 4 days ago
The DEXTRO Little Italy, BW Premier Collection

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Frequently asked questions

Are you searching for a great accommodation for your luxury holiday in Mission Valley?
Expedia can help you arrange a flight to San Diego, CA (MYF-Montgomery Field) airport or San Diego, CA (SAN-San Diego Intl.) airport, and then you can select from various places to stay that will deliver the luxury you'd like to find. Amenities are important when you plan a trip, so we make it easy to get what you need to make your stay special. If you want an upscale hotel with fine dining, a spa or several swimming pools, Expedia can help you find the best luxury hotel experience that Mission Valley has to offer. During your visit, you might want to enjoy the beaches and shopping which Mission Valley is known for.
What's there to see and do in Mission Valley?
Experience Mission Valley and visit Mission Valley Mall, Fashion Valley Mall and Snapdragon Stadium. If you have a bit of extra time while you're in the area, you might want to check out San Diego Zoo and Port of San Diego.
How can I get around Mission Valley?
It's easier to get around town in style when you know your options. Take advantage of metro transport at Hazard Center Station, Mission Valley Center Station and Rio Vista Station.