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Our top choices for Mississippi River hotels

River's Edge Motel

River's Edge Motel
2.0 star property
13.6 km from Mississippi River
9.0 out of 10, Wonderful, (363 reviews)
"We were just driving through and needed a place to stay for the night. It was an easy check in and very friendly staff so perfect for us."
United States
Brent
The price is 2.105.600 ₫
2.390.646 ₫ total
includes taxes & fees
18 May - 19 May
River's Edge Motel

The Eagles Nest Inn

The Eagles Nest Inn
3.0 star property
14.2 km from Mississippi River
9.4 out of 10, Exceptional, (23 reviews)
"Best place to stay in town!"
United States
Kimberly
The price is 2.796.500 ₫
3.174.982 ₫ total
includes taxes & fees
10 May - 11 May
The Eagles Nest Inn

Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal
2.5 star property
26.3 km from Mississippi River
6.4 out of 10, (762 reviews)
"the staff was Great!!"
United States
Karen Kay
The price is 1.750.942 ₫
2.033.157 ₫ total
includes taxes & fees
10 May - 11 May
Baymont by Wyndham Hannibal

Riverside Inn Hannibal

Riverside Inn Hannibal
2.5 star property
25.1 km from Mississippi River
9.4 out of 10, Exceptional, (172 reviews)
"Great place to stay!"
United States
Sandy
The price is 3.936.419 ₫
5.451.661 ₫ total
includes taxes & fees
26 May - 27 May
Riverside Inn Hannibal

Best Western On The River

Best Western On The River
2.5 star property
25.3 km from Mississippi River
8.6 out of 10, Excellent, (1,008 reviews)
"Super clean room Hot tub was amazing "
Canada
Paul
The price is 3.631.897 ₫
4.189.355 ₫ total
includes taxes & fees
13 May - 14 May
Best Western On The River

Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
2.5 star property
30.3 km from Mississippi River
9.6 out of 10, Exceptional, (1,001 reviews)
"Room was great and breakfast was fantastic "
United States
Sheila
The price is 3.219.933 ₫
3.746.453 ₫ total
includes taxes & fees
17 May - 18 May
Sleep Inn & Suites Hannibal West

Lighthouse Inn & Suites

Lighthouse Inn & Suites
4.0 star property
25.8 km from Mississippi River
9.0 out of 10, Wonderful, (27 reviews)
"Very nice room, close enough to walk to riverfront attractions. "
United States
Robert
The price is 4.723.861 ₫
5.448.974 ₫ total
includes taxes & fees
10 May - 11 May
Lighthouse Inn & Suites

Super 8 by Wyndham O'Fallon MO/St. Louis Area

Super 8 by Wyndham O'Fallon MO/St. Louis Area
2.0 star property
90.7 km from Mississippi River
6.8 out of 10, (1,003 reviews)
"Property is most definitely dated. Linens were clean and comfortable for a night."
United States
Ashley
The price is 1.834.767 ₫
2.164.108 ₫ total
includes taxes & fees
25 May - 26 May
Super 8 by Wyndham O'Fallon MO/St. Louis Area

Economy Inn Wentzville

Economy Inn Wentzville
2.0 star property
86.8 km from Mississippi River
6.4 out of 10, (533 reviews)
"If you're just looking for a place to stay for a few days it's ok, However the decor is old and outdated"
United States
Nicko
The price is 1.842.400 ₫
2.090.203 ₫ total
includes taxes & fees
15 May - 16 May
Economy Inn Wentzville

Relax Inn Saint Charles

Relax Inn Saint Charles
2.0 star property
98 km from Mississippi River
6.8 out of 10, (1,000 reviews)
"What I liked about the property is that it’s affordable, with comfort to make you feel like your at home."
United States
Tamerra
The price is 1.658.160 ₫
1.905.568 ₫ total
includes taxes & fees
8 May - 9 May
Relax Inn Saint Charles

Garden House Bed and Breakfast

Garden House Bed and Breakfast
2.0 star property
25.2 km from Mississippi River
8.4 out of 10, Very good, (43 reviews)
"Very welcoming hosts, they went the extra mile and had a very comfortable bed! There were lots of cool antiques and they knew a lot of history on the home itself. We would recommend staying here again. "
United States
Andy Nicole
The price is 2.818.872 ₫
3.251.573 ₫ total
includes taxes & fees
30 May - 31 May
Garden House Bed and Breakfast

Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
2.5 star property
26.2 km from Mississippi River
7.6 out of 10, Good, (690 reviews)
"Beds comfortable- nice breakfast choices. A pleasant peaceful setting "
United States
Wanda J
The price is 2.475.960 ₫
2.934.822 ₫ total
includes taxes & fees
17 May - 18 May
Comfort Inn & Suites - Hannibal

Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal
2.0 star property
26.4 km from Mississippi River
7.4 out of 10, Good, (234 reviews)
"Nice room and great location. Well maintained. Economy choice."
United States
Edward
The price is 1.658.160 ₫
1.912.688 ₫ total
includes taxes & fees
24 May - 25 May
Days Inn by Wyndham Hannibal

Motel 6 Hannibal, MO

Motel 6 Hannibal, MO
2.0 star property
26.1 km from Mississippi River
7.4 out of 10, Good, (1,001 reviews)
"Great stay with no issues at all."
Canada
Thomas
The price is 1.710.927 ₫
1.973.397 ₫ total
includes taxes & fees
25 May - 26 May
Motel 6 Hannibal, MO

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
2.5 star property
30 km from Mississippi River
8.0 out of 10, Very good, (1,008 reviews)
"Great property, good breakfast. "
United States
Bree
The price is 2.250.083 ₫
2.617.972 ₫ total
includes taxes & fees
7 Jun - 8 Jun
Quality Inn & Suites Hannibal West

Baymont by Wyndham Keokuk

Baymont by Wyndham Keokuk
2.5 star property
96.1 km from Mississippi River
6.2 out of 10, (510 reviews)
"I would book this same hotel again . It’s older, but very accommodating. "
United States
Michael
The price is 2.202.984 ₫
2.467.500 ₫ total
includes taxes & fees
16 May - 17 May
Baymont by Wyndham Keokuk

Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal
2.0 star property
26.3 km from Mississippi River
7.4 out of 10, Good, (166 reviews)
"Pet friendly, clean room, great staff and delicious breakfast "
United States
Melissa
The price is 1.650.903 ₫
1.917.059 ₫ total
includes taxes & fees
10 May - 11 May
Howard Johnson BY Wyndham Hannibal

Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal
2.0 star property
26.3 km from Mississippi River
7.2 out of 10, Good, (1,001 reviews)
"Property was clean and staff was friendly."
United States
Etta
The price is 1.776.600 ₫
2.049.275 ₫ total
includes taxes & fees
1 Jun - 2 Jun
Super 8 by Wyndham Hannibal

LAKEVIEWINN

LAKEVIEWINN
2.5 star property
89.4 km from Mississippi River
5.6 out of 10, (47 reviews)
"Good"
United States
Krischel
The price is 1.776.600 ₫
2.006.670 ₫ total
includes taxes & fees
10 May - 11 May
LAKEVIEWINN

La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North

La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North
3.0 star property
109.6 km from Mississippi River
6.6 out of 10, (1,006 reviews)
"Great stay"
United States
Micaela
The price is 1.946.364 ₫
2.379.198 ₫ total
includes taxes & fees
18 May - 19 May
La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Mississippi River

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Property grounds
River's Edge Motel
2.0 star property
9.0
Wonderful
363 reviews
View
Lunch and dinner served, Italian cuisine
The Eagles Nest Inn
3.0 star property
9.4
Exceptional
23 reviews
View
Indoor pool
Baymont by Wyndham Hannibal
2.5 star property
6.4
762 reviews
View
55-inch TV with cable channels, Netflix, Hulu
Riverside Inn Hannibal
2.5 star property
9.4
Exceptional
172 reviews
View
Desk, iron/ironing board, WiFi, bed sheets
Best Western On The River
2.5 star property
8.6
Excellent
1,008 reviews
View

Top Mississippi River Hotel Reviews

Hotels near other Mississippi River attractions

Frequently asked questions

What's the area like around Mississippi River?
Mississippi River is located in an area that travellers like for its baseball games. When you want to settle in and find a place to stay, take a look at some of the hotels and other accommodation options that Expedia offers in the area.
If I need to cancel the hotel reservation for my stay near Mississippi River, will I receive a refund?
Yes! Most room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to review the best deals near Mississippi River.