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Our top choices for Mississippi River hotels

River's Edge Motel

River's Edge Motel
2.0 star property
13.6 km from Mississippi River
9.0 out of 10, Wonderful, (359 reviews)
"Excellent stay !!! Quite "
United States
Bradley
The price is 2.080.160 ₫
2.361.762 ₫ total
includes taxes & fees
5 Feb - 6 Feb
River's Edge Motel

The Eagles Nest Inn

The Eagles Nest Inn
3.0 star property
14.2 km from Mississippi River
9.4 out of 10, Exceptional, (21 reviews)
"Room was spacious and clean. Had a great stay. The restaurant was delicious. "
United States
James
The price is 2.486.301 ₫
2.822.883 ₫ total
includes taxes & fees
7 Feb - 8 Feb
The Eagles Nest Inn

Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal
2.5 star property
26.3 km from Mississippi River
6.4 out of 10, (740 reviews)
"The staff was very welcoming and the room was clean "
United States
Tracy
The price is 1.521.117 ₫
1.758.792 ₫ total
includes taxes & fees
8 Feb - 9 Feb
Baymont by Wyndham Hannibal

Super 8 by Wyndham O'Fallon MO/St. Louis Area

Super 8 by Wyndham O'Fallon MO/St. Louis Area
2.0 star property
90.7 km from Mississippi River
6.8 out of 10, (1,000 reviews)
"Staff was awesome and accomodating. Room and price was great. "
United States
Anthony
The price is 1.635.526 ₫
1.929.104 ₫ total
includes taxes & fees
12 Feb - 13 Feb
Super 8 by Wyndham O'Fallon MO/St. Louis Area

Economy Inn Wentzville

Economy Inn Wentzville
2.0 star property
86.8 km from Mississippi River
6.4 out of 10, (517 reviews)
"The heating unit was noise, the sink was plumbed backwards but the room was clean."
United States
Gordon
The price is 1.560.120 ₫
1.769.956 ₫ total
includes taxes & fees
5 Feb - 6 Feb
Economy Inn Wentzville

Riverside Inn Hannibal

Riverside Inn Hannibal
2.5 star property
25.1 km from Mississippi River
9.4 out of 10, Exceptional, (166 reviews)
"Great place to stay!"
United States
Sandy
The price is 3.699.443 ₫
5.144.710 ₫ total
includes taxes & fees
5 Feb - 6 Feb
Riverside Inn Hannibal

Best Western On The River

Best Western On The River
2.5 star property
25.3 km from Mississippi River
8.6 out of 10, Excellent, (1,000 reviews)
"Everything was great. Will definitely stay again."
United States
Ethan
The price is 2.105.902 ₫
2.418.446 ₫ total
includes taxes & fees
11 Feb - 12 Feb
Best Western On The River

Relax Inn Saint Charles

Relax Inn Saint Charles
2.0 star property
98 km from Mississippi River
6.6 out of 10, (1,001 reviews)
"Clean room very nice staff it’s nice"
United States
Mercedez
The price is 1.638.126 ₫
1.882.545 ₫ total
includes taxes & fees
5 Feb - 6 Feb
Relax Inn Saint Charles

Days Inn by Wyndham St Peters/St Charles

Days Inn by Wyndham St Peters/St Charles
2.0 star property
93.8 km from Mississippi River
6.2 out of 10, (1,000 reviews)
"Room was excellent and clean"
United States
catherine
The price is 1.458.712 ₫
1.676.789 ₫ total
includes taxes & fees
9 Feb - 10 Feb
Days Inn by Wyndham St Peters/St Charles

Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
2.5 star property
30.3 km from Mississippi River
9.6 out of 10, Exceptional, (1,002 reviews)
"Clean and great location!"
United States
janet
The price is 2.630.102 ₫
3.046.974 ₫ total
includes taxes & fees
1 Mar - 2 Mar
Sleep Inn & Suites Hannibal West

La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North

La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North
3.0 star property
109.6 km from Mississippi River
6.6 out of 10, (1,005 reviews)
"Great staff and the place is nice and clean and the breakfast is awesome."
United States
Kerry
The price is 1.525.017 ₫
1.864.150 ₫ total
includes taxes & fees
1 Mar - 2 Mar
La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North

Extended Stay America Select Suites St Louis Earth City

Extended Stay America Select Suites St Louis Earth City
2.5 star property
107.1 km from Mississippi River
6.6 out of 10, (885 reviews)
"Nothing bad to say about this Hotel. Great, clean rooms and awesome staff."
United States
Charles
The price is 1.920.016 ₫
2.309.796 ₫ total
includes taxes & fees
6 Feb - 7 Feb
Extended Stay America Select Suites St Louis Earth City

Baymont by Wyndham Keokuk

Baymont by Wyndham Keokuk
2.5 star property
96.1 km from Mississippi River
6.2 out of 10, (497 reviews)
"I had to pay for my family to swim in the pool. The poll area was hazardous because there was drywall pealing off from the ceiling and around the pool. "
United States
Clarence and Kari
The price is 1.497.715 ₫
1.677.389 ₫ total
includes taxes & fees
15 Feb - 16 Feb
Baymont by Wyndham Keokuk

Super 8 by Wyndham Bowling Green

Super 8 by Wyndham Bowling Green
2.0 star property
23.9 km from Mississippi River
8.4 out of 10, Very good, (490 reviews)
"Front desk people,...both evening 25th and morning 26th were very pleasant and helpful."
United States
Leroy
Super 8 by Wyndham Bowling Green

LAKEVIEWINN

LAKEVIEWINN
2.5 star property
89.4 km from Mississippi River
5.4 out of 10, (33 reviews)
"I enjoyed it! And the owners were so sweet and understanding. I would absolutely stay there again!"
United States
Evelyn
The price is 1.755.135 ₫
1.982.392 ₫ total
includes taxes & fees
5 Feb - 6 Feb
LAKEVIEWINN

Lighthouse Inn & Suites

Lighthouse Inn & Suites
4.0 star property
25.8 km from Mississippi River
8.8 out of 10, Excellent, (25 reviews)
"Nice room. Matched the pictures. Exactly what we were looking for."
United States
John
The price is 4.390.645 ₫
5.042.657 ₫ total
includes taxes & fees
7 Feb - 8 Feb
Lighthouse Inn & Suites

Americas Best Value Inn & Suites St. Louis, St. Charles Inn

Americas Best Value Inn & Suites St. Louis, St. Charles Inn
2.5 star property
103.4 km from Mississippi River
5.8 out of 10, (1,005 reviews)
"Great place"
United States
Christina
The price is 1.434.270 ₫
1.662.706 ₫ total
includes taxes & fees
1 Mar - 2 Mar
Americas Best Value Inn & Suites St. Louis, St. Charles Inn

Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
2.5 star property
26.2 km from Mississippi River
7.6 out of 10, Good, (672 reviews)
"Room was spacious and very clean. Bed comfortable. Breakfast was great! Staff friendly and helpful. "
United States
Judy
The price is 1.968.871 ₫
2.339.255 ₫ total
includes taxes & fees
2 Mar - 3 Mar
Comfort Inn & Suites - Hannibal

Garden House Bed and Breakfast

Garden House Bed and Breakfast
2.0 star property
25.2 km from Mississippi River
8.6 out of 10, Excellent, (38 reviews)
"Great location. Clean rooms, Staff very friendly."
United States
Charles
The price is 2.784.814 ₫
3.198.506 ₫ total
includes taxes & fees
6 Feb - 7 Feb
Garden House Bed and Breakfast

Sleep Inn Saint Charles North

Sleep Inn Saint Charles North
2.5 star property
97.1 km from Mississippi River
5.8 out of 10, (521 reviews)
"The staff was very helpful the rooms where nice very affordable clean and very quiet"
United States
Valerie
The price is 1.783.737 ₫
2.049.994 ₫ total
includes taxes & fees
26 Feb - 27 Feb
Sleep Inn Saint Charles North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Mississippi River Hotel Reviews

Hotels near other Mississippi River attractions

Frequently asked questions

What's the area like around Mississippi River?
Mississippi River is located in an area that travellers like for its baseball games. When you want to settle in and find a place to stay, take a look at some of the hotels and other accommodation options that Expedia offers in the area.
If I need to cancel the hotel reservation for my stay near Mississippi River, will I receive a refund?
Yes! Most room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to review the best deals near Mississippi River.