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Check availability on Muscatine Luxury Hotels

Our top choices for Muscatine luxury hotels

Breakfast, lunch, dinner served; American cuisine
The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel

The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel

The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
4.0 star property
Muscatine
9.6 out of 10, Exceptional, (277)
"Great Hotel. The restaurant, Maxwell's was very good."
United States
Dennis
The price is 4.449.601 ₫
4.983.553 ₫ total
includes taxes & fees
9 Jan - 10 Jan 2026
The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
Lobby
DoubleTree by Hilton Davenport

DoubleTree by Hilton Davenport

DoubleTree by Hilton Davenport
4.0 star property
Downtown Davenport
7.4 out of 10, Good, (1003)
"Staff was awesome, room was clean"
United States
Holly
The price is 1.904.218 ₫
2.132.724 ₫ total
includes taxes & fees
22 Dec - 23 Dec
DoubleTree by Hilton Davenport
City view from property
The Current Iowa, Autograph Collection

The Current Iowa, Autograph Collection

The Current Iowa, Autograph Collection
4.0 star property
Downtown Davenport
9.2 out of 10, Wonderful, (603)
"Room decor was trendy and bathroom was completely updated which was nice. "
United States
Kimberly
The price is 3.291.125 ₫
3.686.061 ₫ total
includes taxes & fees
21 Dec - 22 Dec
The Current Iowa, Autograph Collection
Terrace/patio
Hotel Blackhawk, Autograph Collection

Hotel Blackhawk, Autograph Collection

Hotel Blackhawk, Autograph Collection
4.0 star property
Downtown Davenport
9.2 out of 10, Wonderful, (896)
"Room was clean and all of the staff were helpful"
United States
Bob
The price is 3.528.086 ₫
3.951.456 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Hotel Blackhawk, Autograph Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Are you searching for a great accommodation for your luxury getaway to Muscatine?
Use Expedia to help you arrange a flight to Moline, IL (MLI-Quad City Intl.) airport, and then choose from a variety of places to stay that will deliver the luxury you want. Amenities are important when you plan a trip, so we make it easy to get what you need to make your stay relaxing and comfortable. If you want an upscale hotel with fine dining, a spa or several swimming pools, Expedia can help you find the best luxury hotel experience that Muscatine has to offer. Muscatine has some interesting things to see and do including Mississippi River and Wildcat Den State Park, so you might want to take in the local sights during your visit.
When can I expect good weather in Muscatine?
Planning for the weather is an important factor for making your trip to Muscatine a success, especially when you're splurging. The hottest months are usually July and August, with an average temperature of 22°C, while the coldest months are January and February, with an average of -1°C. The snowiest months in Muscatine are January, November, February and December, with each month seeing an average of 18 cm of snowfall.
What's there to see and do in Muscatine?
Enjoy Muscatine with a stop at Mississippi River, Wildcat Den State Park and Pine Creek Grist Mill. If you have spare time during your trip, you might want to make a stop at Cedar River and Riverside Park.