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Our top choices for Museum of Natural Science hotels

Restaurant
Hyatt Regency Panama City

Hyatt Regency Panama City

Hyatt Regency Panama City
4.5 star property
Campo Alegre, 2 km from Museum of Natural Science
10.0 out of 10, Exceptional, (127)
"Great hotel fair price"
United States
Santiago
The price is 4.124.876 ₫
4.537.364 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
Hyatt Regency Panama City
Daily full breakfast for a fee
Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
4.5 star property
San Felipe, 1.6 km from Museum of Natural Science
9.8 out of 10, Exceptional, (258)
"Great location!"
United States
Erik
The price is 8.477.377 ₫
9.325.115 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Hotel La Compañía Casco Antiguo
Exterior
Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
San Felipe, 1.8 km from Museum of Natural Science
9.8 out of 10, Exceptional, (560)
"Great hotel and location "
United Kingdom
Russell
The price is 9.828.653 ₫
10.811.518 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
Sofitel Legend Casco Viejo, Panama City
Breakfast and dinner served, international cuisine
Amarla Boutique Hotel Casco Viejo

Amarla Boutique Hotel Casco Viejo

Amarla Boutique Hotel Casco Viejo
3.0 star property
San Felipe, 1.7 km from Museum of Natural Science
9.6 out of 10, Exceptional, (106)
"Great little hotel in Casco Viejo. Rooms are small, but comfortable. Reception is a bit odd, but service was nice. "
United States
Frederick
Amarla Boutique Hotel Casco Viejo
Front of property
La Concordia Boutique Hotel

La Concordia Boutique Hotel

La Concordia Boutique Hotel
4.0 star property
San Felipe, 1.6 km from Museum of Natural Science
9.6 out of 10, Exceptional, (194)
"Beautiful room Good location"
United States
Karla
The price is 7.846.344 ₫
8.631.057 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
La Concordia Boutique Hotel
Front of property
Hotel San Felipe

Hotel San Felipe

Hotel San Felipe
4.0 star property
San Felipe, 1.6 km from Museum of Natural Science
9.4 out of 10, Exceptional, (253)
"Nice hotel, perfect area in the old quarter. Clean, comfortable, great staff. Highly recommend!"
Canada
Neil
The price is 3.069.381 ₫
3.376.319 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hotel San Felipe
Front of property – evening/night
American Trade Hotel

American Trade Hotel

American Trade Hotel
4.5 star property
San Felipe, 1.7 km from Museum of Natural Science
9.4 out of 10, Exceptional, (607)
"Excellent service and great rooms on a beautiful and historical building"
Canada
Manuel
The price is 7.673.454 ₫
8.440.799 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
American Trade Hotel
Couples treatment room(s), sauna, steam room, body treatments
Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
5.0 star property
Campo Alegre, 2 km from Museum of Natural Science
9.4 out of 10, Exceptional, (1000)
"Great staff, super accommodating. Best place to stay in Panama!"
United States
Sebastian
The price is 5.278.789 ₫
5.806.668 ₫ total
includes taxes & fees
14 Jan - 15 Jan 2026
Bristol Panama, a Registry Collection Hotel
Lobby
The Executive Hotel

The Executive Hotel

The Executive Hotel
3.5 star property
Campo Alegre, 2 km from Museum of Natural Science
9.2 out of 10, Wonderful, (1004)
"A nice hotel to stay great location"
United States
angela
The Executive Hotel
Luxury Apartment | Balcony
Casco View Apartments

Casco View Apartments

Casco View Apartments
3.5 star property
Santa Ana, 1.5 km from Museum of Natural Science
9.2 out of 10, Wonderful, (55)
"We live this property and stay here whenever we are in town."
United States
chris
Casco View Apartments
Outdoor pool
MARINN PLACE Financial District

MARINN PLACE Financial District

MARINN PLACE Financial District
3.5 star property
Campo Alegre, 2.1 km from Museum of Natural Science
9.2 out of 10, Wonderful, (299)
"Second stay, very nice"
Canada
Xiaozhi
The price is 2.947.280 ₫
3.242.008 ₫ total
includes taxes & fees
22 Dec - 23 Dec
MARINN PLACE Financial District
Terrace/patio
Marriott Panama Hotel

Marriott Panama Hotel

Marriott Panama Hotel
4.0 star property
1.8 km from Museum of Natural Science
9.0 out of 10, Wonderful, (1007)
"Great hotel and staff!"
United States
Catherine
The price is 3.927.514 ₫
4.320.397 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Marriott Panama Hotel
View from property
Waldorf Astoria Panama

Waldorf Astoria Panama

Waldorf Astoria Panama
5.0 star property
Bella Vista, 1.7 km from Museum of Natural Science
9.0 out of 10, Wonderful, (1002)
"I loved everything about my stay "
United States
Stephanie
The price is 5.804.563 ₫
6.385.019 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
Waldorf Astoria Panama
47-inch flat-screen TV with cable channels, TV
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
4.0 star property
San Felipe, 1.7 km from Museum of Natural Science
9.0 out of 10, Wonderful, (1010)
"Excellent hotel , good breakfast, great location, would highly recommend "
United States
Glen
The price is 5.576.440 ₫
6.134.084 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Central Hotel Panama Casco Viejo
2 restaurants, local cuisine
W Panama

W Panama

W Panama
5.0 star property
Campo Alegre, 2 km from Museum of Natural Science
9.0 out of 10, Wonderful, (1006)
"Great vibes"
United States
Ashley
The price is 5.241.948 ₫
5.766.143 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
W Panama
Living area
Magnolia Inn

Magnolia Inn

Magnolia Inn
2.0 star property
San Felipe, 1.6 km from Museum of Natural Science
8.8 out of 10, Excellent, (415)
"Excelent location , friendly staff and cute hotel"
Canada
Renata
The price is 2.219.091 ₫
2.441.000 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Magnolia Inn
Breakfast, lunch, dinner served; Fusion cuisine
Tantalo Hotel

Tantalo Hotel

Tantalo Hotel
3.5 star property
San Felipe, 1.5 km from Museum of Natural Science
8.8 out of 10, Excellent, (275)
"Staff was amazing!! Room was great as well!! "
United States
John
Tantalo Hotel
Outdoor pool
Marriott Executive Apartments Panama City, Finisterre

Marriott Executive Apartments Panama City, Finisterre

Marriott Executive Apartments Panama City, Finisterre
4.0 star property
Campo Alegre, 1.6 km from Museum of Natural Science
8.8 out of 10, Excellent, (654)
"Good staff, rooms very well done with daily service. Pool and sauna always clean and well maintained. Lots of towels. Location ideal for transportation to the attractions like Panama City, Casco veijo, airport and others."
United States
Shyamala
The price is 2.885.440 ₫
3.173.984 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
Marriott Executive Apartments Panama City, Finisterre
Outdoor pool
Hilton Panama

Hilton Panama

Hilton Panama
5.0 star property
Bella Vista, 1.9 km from Museum of Natural Science
8.8 out of 10, Excellent, (1001)
"Nice room! Clean. Nice balcony, "
United States
Cassandra
The price is 5.532.466 ₫
6.085.607 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Hilton Panama
Standard Apartment | Living area | Flat-screen TV
Torres de Alba Hotel & Suites

Torres de Alba Hotel & Suites

Torres de Alba Hotel & Suites
3.5 star property
El Cangrejo, 2.2 km from Museum of Natural Science
8.8 out of 10, Excellent, (483)
"The buffet bar and great customer service. "
United States
Kayhiuska
Torres de Alba Hotel & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Museum of Natural Science Hotel Reviews

Hotels near other Museum of Natural Science attractions

Cinta Costera

4.5/5 (1,357 reviews)
Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.
See properties

National Bank House Museum

You can browse the exhibits at National Bank House Museum, a museum with a story of its own, during your holiday in Panama City. Amble around this vibrant area's seaside and enjoy its top-notch restaurants.
See properties

Frequently asked questions

What's the area like around Museum of Natural Science?
Museum of Natural Science is located in a scenic area of Panama City known for its major shopping area and interesting historical sites. If you're looking for a convenient place to stay, take a look at the 406 hotels and other accommodation options you'll find within a mile.
How many hotels can I expect to find close to Museum of Natural Science?
Expedia has 406 hotels and other accommodation options within a mile from Museum of Natural Science.
If I need to cancel the hotel reservation for my stay near Museum of Natural Science, will I receive a refund?
Yes, you'll find most room reservations are fully refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of booking. Add your dates and click on "Search", then use the "fully refundable" filter to get top deals close to Museum of Natural Science.
What can I see and do near Museum of Natural Science?
You'll want to browse the collections at Interoceanic Canal Museum, National Bank House Museum and Afro Antillean Museum. Iglesia del Carmen, Panama Canal Railway and Miraflores Locks are notable landmarks to explore if you're in the area. You can check out the local talent at National Theater, Amador Theater and Anita Villalaz Theater.
How can I get to Museum of Natural Science?
Nearby metro stations include Estación Lotería and Santo Tomas Station. If you'd like to venture farther outside of the area, consider renting a car to take in more sights.

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