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Our top choices for North Clayton hotels

Outdoor dining
Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Hampton Inn & Suites Clayton/St. Louis-Galleria Area
3.0 star property
North Clayton
9.0 out of 10, Wonderful, (915)
"Clean room, friendly staff."
United States
Patrick George
The price is 2.999.384 ₫
3.531.414 ₫ total
includes taxes & fees
19 Jan - 20 Jan 2026
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Lobby
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis, 13.7 km from North Clayton
8.4 out of 10, Very good, (4028)
"Everything was great!"
United States
Kathryn
The price is 2.605.185 ₫
3.072.269 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Hyatt Regency St. Louis at The Arch
Breakfast, lunch and dinner served
Live by Loews - St.Louis

Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis, 13.3 km from North Clayton
9.4 out of 10, Exceptional, (1107)
"Clean room, great restaurant and bar down stairs "
United States
Ambria
The price is 3.920.935 ₫
4.663.130 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Live by Loews - St.Louis
Seasonal outdoor pool
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
17.7 km from North Clayton
8.4 out of 10, Very good, (1007)
"Clean room, wonderful helpful pleasant staff, amenities, everything was great love staying here!"
United States
Robyn
The price is 4.003.827 ₫
5.115.636 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Ameristar Casino Resort and Spa
Front of property
Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
Downtown St. Louis, 13.7 km from North Clayton
8.8 out of 10, Excellent, (1018)
"My second time staying there as always it was lovely "
United States
Nina
The price is 2.715.708 ₫
3.202.607 ₫ total
includes taxes & fees
27 Dec - 28 Dec
Hilton Pennywell St. Louis at the Arch
Exterior
Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis, 13.4 km from North Clayton
8.8 out of 10, Excellent, (1242)
"Great hospitality"
United States
Alejandro
The price is 2.891.492 ₫
3.438.821 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Embassy Suites by Hilton St. Louis Downtown
Bar (on property)
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis, 13.3 km from North Clayton
8.8 out of 10, Excellent, (1160)
"Really enjoyed my stay! Highly recommend this place. It’s a vintage style hotel that is very well kept uo"
United States
Varun
The price is 2.107.831 ₫
2.506.823 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Courtyard
The Knight Center at Washington University

The Knight Center at Washington University

The Knight Center at Washington University
2.5 star property
2.7 km from North Clayton
9.4 out of 10, Exceptional, (447)
"Awesome place to stay!"
United States
james
The price is 3.332.795 ₫
3.832.313 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
The Knight Center at Washington University
Indoor pool, open 8:00 AM to 10:00 PM, pool loungers
La Quinta Inn & Suites by Wyndham St Louis Route 66

La Quinta Inn & Suites by Wyndham St Louis Route 66

La Quinta Inn & Suites by Wyndham St Louis Route 66
3.0 star property
12.3 km from North Clayton
8.0 out of 10, Very good, (1003)
"Nice Staff, Clean Rooms, Good Area!!"
United States
Keyaira
The price is 2.527.556 ₫
2.937.980 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
La Quinta Inn & Suites by Wyndham St Louis Route 66
Indoor pool, open 6:00 AM to 10:00 PM, pool loungers
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
2.5 star property
Downtown St. Louis, 13.8 km from North Clayton
8.8 out of 10, Excellent, (1180)
"Breakfast was great and this was my seventh year staying there."
United States
Derick
The price is 2.567.818 ₫
3.002.524 ₫ total
includes taxes & fees
27 Dec - 28 Dec
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Lobby
Missouri Athletic Club

Missouri Athletic Club

Missouri Athletic Club
3.5 star property
Downtown St. Louis, 13.7 km from North Clayton
8.8 out of 10, Excellent, (1000)
"The room was nice and the staff was excellent."
United States
Annette
The price is 4.447.235 ₫
5.200.107 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Missouri Athletic Club
Free daily buffet breakfast
Tru By Hilton St. Louis Downtown

Tru By Hilton St. Louis Downtown

Tru By Hilton St. Louis Downtown
2.5 star property
Downtown West, 12.7 km from North Clayton
7.6 out of 10, Good, (594)
"Breakfast was delicious and room was comfy "
United States
Ronnesha
The price is 2.136.252 ₫
2.497.898 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Tru By Hilton St. Louis Downtown
Lobby
St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
4.0 star property
Downtown West, 12 km from North Clayton
8.6 out of 10, Excellent, (1004)
"The hotel itself was just beautiful and grand! Beautifully decorated for the holidays and the amenities and attractions surrounding Union station were perfect for our family of 4! Our room was spacious and clean and we loved our stay! "
United States
Kelly
The price is 4.121.455 ₫
4.901.607 ₫ total
includes taxes & fees
28 Dec - 29 Dec
St. Louis Union Station Hotel, Curio Collection by Hilton
Free breakfast
Best Western Plus Fenton

Best Western Plus Fenton

Best Western Plus Fenton
2.5 star property
15.6 km from North Clayton
9.2 out of 10, Wonderful, (179)
"Clean room, nice staff, great food, and great service "
United States
Thuy
The price is 2.667.288 ₫
3.080.397 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Best Western Plus Fenton
3 bars/lounges, rooftop bar
Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark
4.0 star property
Downtown St. Louis, 13.5 km from North Clayton
7.6 out of 10, Good, (1067)
"Clean room, this hotel is great for young people, night activity, 360 rooftop bar always crowded but pretty."
United States
Joan
The price is 3.646.733 ₫
4.337.023 ₫ total
includes taxes & fees
27 Dec - 28 Dec
Hilton St. Louis at the Ballpark
Restaurant
21C Museum Hotel St Louis

21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West, 12.4 km from North Clayton
9.0 out of 10, Wonderful, (1508)
"Hotel was comfortable, clean and unique. All staff was wonderful "
United States
Sharon
The price is 3.528.842 ₫
4.257.814 ₫ total
includes taxes & fees
29 Dec - 30 Dec
21C Museum Hotel St Louis
Terrace/patio
Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood
3.0 star property
3 km from North Clayton
9.4 out of 10, Exceptional, (838)
"Clean, would stay again."
United States
Eryka
The price is 2.661.762 ₫
3.265.482 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Courtyard by Marriott St. Louis Brentwood
Property amenity
Moonrise Hotel

Moonrise Hotel

Moonrise Hotel
4.0 star property
3.7 km from North Clayton
9.0 out of 10, Wonderful, (1917)
"Clean rooms, good coffee and fresh muffins and friendly service."
United States
Colleen
The price is 2.964.579 ₫
3.525.745 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Moonrise Hotel
Gastropub
The Cheshire

The Cheshire

The Cheshire
4.0 star property
3.8 km from North Clayton
8.6 out of 10, Excellent, (1003)
"Excellent place to stay. "
United States
Todd
The price is 3.026.248 ₫
3.593.306 ₫ total
includes taxes & fees
29 Dec - 30 Dec
The Cheshire
Lobby
Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield
3.0 star property
19.1 km from North Clayton
9.6 out of 10, Exceptional, (1037)
"Absolutely amazing stay very nice play our family stays there every time very kid friendly"
United States
Matthew
The price is 3.420.687 ₫
3.967.513 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Drury Plaza Hotel St. Louis Chesterfield
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in North Clayton

Find the best North Clayton areas for the activities you enjoy most.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Saint Louis Abbey while you're in town.

Central West End

Central West End

If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.

Top North Clayton Hotel Reviews

Frequently asked questions

What is North Clayton like?
Travellers to St. Louis's North Clayton neighbourhood will be sure to enjoy a stay here.
If I need to cancel my hotel reservation in North Clayton, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you have a reservation that's non-refundable, you may still be able to cancel and be given a refund within 24 hours of booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to view the best deals available in North Clayton.
What is there to do in this St. Louis neighbourhood?
Shaw Park Tennis Center, Saint Louis Galleria Mall and Heman Park Tennis Center are just a few of the places to visit in and around North Clayton. While you're out sightseeing, Tao Tennis Center and Center of Creative Arts are a couple of additional sights to visit in St. Louis.