
Ortigia Holidays
Book a Hotel + Flight or Car together to unlock savings
Where to stay in Ortigia
Find the best Ortigia areas and neighborhoods for the activities you enjoy most. Learn more about Ortigia

Santa Lucia
1 out of top 10 points of interest in this area
4.5/5(17 area reviews)
Santa Lucia is noteworthy for its historical sites, and you can make a stop at top attractions like Porto Piccolo and Ionian Sea.
Top hotels in Ortigia

Algila' Ortigia Charme Hotel
Via Vittorio Veneto 93, Syracuse, SR
Fully refundableReserve now, pay when you stay
9.4/10 Exceptional! (847 reviews)
"We loved this hotel -- the location is perfect and the staff couldn't be more helpful and lovely. The AC is strong and the facilities are well maintained. The included breakfast is comprehensive and delicious!! Shoutout to Sabrina at the front desk who was extra helpful to us when trying to get our ..."
Reviewed on 29 Jul 2025

Ortea Palace Hotel, Sicily, Autograph Collection
Via Riva Nazario Sauro, Syracuse, SR
Fully refundableReserve now, pay when you stay
The price is 9.777.715 ₫ per night from 1 Aug to 2 Aug
9.777.715 ₫
11.054.915 ₫ total
1 Aug - 2 Aug
includes taxes & fees
9.2/10 Wonderful! (238 reviews)
"Amazing property in Syracusa. Do not miss this majestic property close to shopping, activities and dinning."
Reviewed on 23 Jul 2025

Palazzo Artemide - VRetreats
Via Roma 66, Syracuse, SR
Fully refundableReserve now, pay when you stay
The price is 5.230.172 ₫ per night from 18 Aug to 19 Aug
5.230.172 ₫
6.918.870 ₫ total
18 Aug - 19 Aug
includes taxes & fees
9.4/10 Exceptional! (637 reviews)
"Very good hotel. You won’t regret!"
Reviewed on 26 Jul 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Popular places to visit

Piazza del Duomo
You can find out about the history of Syracuse with a trip to Piazza del Duomo. Wander through the beautiful beaches and seaside in this culturally rich area.

Roman Amphitheatre of Syracuse
You can learn about the history of Syracuse with a trip to Roman Amphitheatre of Syracuse. Wander the seaside in this culturally rich area.

Catacombs of St. John
Learn about the local history of Syracuse when you spend time at Catacombs of St. John. Wander the seaside in this culturally rich area.