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Our top choices for Prague 21 hotels

Dvůr Hoffmeister

Dvůr Hoffmeister
3.0 star property
31.9 km from Prague 21
9.6 out of 10, Exceptional, (89)
"The lovely bathroom and jet tub Place was pretty nice and away from the busy tourist areas "
United States
Natisha
Dvůr Hoffmeister

Wellness Hotel Step

Wellness Hotel Step
4.0 star property
13.6 km from Prague 21
8.0 out of 10, Very good, (194)
"Clean room and good breakfast "
Australia
Haoyu
Wellness Hotel Step

Hapimag Resort Prague

Hapimag Resort Prague
3.5 star property
Nové Město, 17.4 km from Prague 21
9.4 out of 10, Exceptional, (56)
"Staff were very helpful- lovely rooms - close to old town "
United States
julia
The price is 4.098.303 ₫
4.717.439 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Hapimag Resort Prague

Hilton Prague

Hilton Prague
5.0 star property
16.7 km from Prague 21
8.4 out of 10, Very good, (1002)
"Very excellent Hotel would recommend to anyone!"
Canada
Damien
The price is 2.048.754 ₫
2.420.608 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Hilton Prague

Hotel Royal Prague

Hotel Royal Prague
2.5 star property
Karlín, 15.9 km from Prague 21
8.8 out of 10, Excellent, (371)
"Great ambience!"
United States
ANTON
Hotel Royal Prague

Hotel Duo & Wellness

Hotel Duo & Wellness
4.0 star property
14.2 km from Prague 21
8.4 out of 10, Very good, (1001)
"Nice stay, can’t complain "
United Kingdom
Nicole
The price is 1.541.167 ₫
1.853.349 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Hotel Duo & Wellness

Panorama by Verdi Hotels

Panorama by Verdi Hotels
4.5 star property
17.1 km from Prague 21
8.6 out of 10, Excellent, (1000)
"Awesome spot, nice rooms full bar and restaurant. "
United States
Lizeth
The price is 1.691.240 ₫
2.021.529 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Panorama by Verdi Hotels

ibis Praha Mala Strana

ibis Praha Mala Strana
3.0 star property
19.4 km from Prague 21
8.4 out of 10, Very good, (722)
"Clean rooms, friendly staff"
United States
David
The price is 1.335.357 ₫
1.622.940 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
ibis Praha Mala Strana

Hotel PULSE8

Hotel PULSE8
4.0 star property
Karlín, 15.7 km from Prague 21
9.0 out of 10, Wonderful, (837)
"overall good feeling and experience "
United States
Jan
The price is 2.789.212 ₫
3.251.777 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hotel PULSE8

Hotel Valcha

Hotel Valcha
3.0 star property
21.9 km from Prague 21
9.2 out of 10, Wonderful, (58)
"Front desk reception was amazing and the staff that works there "
United States
Ruben
The price is 1.598.248 ₫
1.914.192 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Hotel Valcha

B&B Hotel Prague-City

B&B Hotel Prague-City
2.0 star property
Karlín, 16.6 km from Prague 21
8.8 out of 10, Excellent, (163)
"Clean, reasonably priced and very convenient for lots of travel options to the centre of Prague and beyond. "
United Kingdom
Les
The price is 1.804.368 ₫
2.148.232 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
B&B Hotel Prague-City

Grand Hotel Prague Towers

Grand Hotel Prague Towers
5.0 star property
Nusle, 17.3 km from Prague 21
8.4 out of 10, Very good, (1001)
"Everyone was so nice. The hotel is great. The food, room, location next to metro was great everything gets a perfect score. "
United States
Fauzia
The price is 2.640.583 ₫
2.957.453 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Grand Hotel Prague Towers

Avenue Legerova 19

Avenue Legerova 19
3.0 star property
Nové Město, 17.3 km from Prague 21
9.0 out of 10, Wonderful, (489)
"깨끗하고 가격이 좋았습니다. 아쉬운점은 주차할때가 없어 길가에 주차 했던 기억이 나는군요"
South Korea
Jin sup
The price is 1.834.510 ₫
2.180.658 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Avenue Legerova 19

Hotel Villa

Hotel Villa
4.0 star property
13.6 km from Prague 21
9.2 out of 10, Wonderful, (221)
"Great hotel with a decent restaurant"
United States
Tafara
Hotel Villa

Ankora Hotel Prague

Ankora Hotel Prague
3.0 star property
Nové Město, 17.6 km from Prague 21
8.6 out of 10, Excellent, (297)
"Clean room, staff are courteous, we just wished they have full body mirror 😊 walkable to most tourists attractions area. "
Canada
Numida
The price is 1.340.145 ₫
1.628.204 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Ankora Hotel Prague

Prague Centre Plaza

Prague Centre Plaza
3.0 star property
Nové Město, 17.4 km from Prague 21
7.8 out of 10, Good, (447)
"Good location, good service. Enjoyed my stay."
United Kingdom
Joseph
Prague Centre Plaza

INNSiDE by Meliá Prague Old Town

INNSiDE by Meliá Prague Old Town
4.0 star property
Petrská čtvrť, 17.3 km from Prague 21
9.6 out of 10, Exceptional, (1004)
"Lovely room and staff really friendly"
United Kingdom
Mark
The price is 2.812.651 ₫
3.274.940 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
INNSiDE by Meliá Prague Old Town

City Pop 2Night Prague - Self check-in

City Pop 2Night Prague - Self check-in
4.0 star property
Nové Město, 17.3 km from Prague 21
9.0 out of 10, Wonderful, (325)
"Good location, would stay there again."
Canada
Dawn
The price is 1.890.778 ₫
2.245.011 ₫ total
includes taxes & fees
15 Dec - 16 Dec
City Pop 2Night Prague - Self check-in

Hotel Golf Prague

Hotel Golf Prague
4.0 star property
23.6 km from Prague 21
8.8 out of 10, Excellent, (638)
"Staff were okay, the hotel is very clean, and breakfast was great!!! All fresh foods!! I wish parking was a bit cheaper though. I would definitely recommend "
United States
Philomena
The price is 2.051.581 ₫
2.425.013 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Hotel Golf Prague

ibis Praha Wenceslas Square

ibis Praha Wenceslas Square
3.0 star property
Nové Město, 17.5 km from Prague 21
8.2 out of 10, Very good, (602)
"From.check-in to check-out was great"
United Kingdom
Barry
The price is 1.569.016 ₫
1.884.638 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
ibis Praha Wenceslas Square
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Prague 21

Find the best Prague 21 areas for the activities you enjoy most.

Prague City Center

Charles Bridge Museum and Museum of Medieval Torture are top sights in Prague City Center, and you should be sure to explore the acclaimed art galleries. Hop aboard the metro at Karlovy Lázně Stop or Staroměstská Stop to see more sights in the area.

Stare Mesto

Gourmet restaurants interesting history and top sights from Havelska Market to Klementinum-Prague National Library – discover Stare Mesto, a destination also famous for its shopping.

Nové Město

Gourmet restaurants interesting history and top sights from Charles Square to New Town Hall – discover Nové Město, a destination also famous for its shopping.

Prague 1

Known for its popular shops and acclaimed art galleries, there's plenty to explore in Prague 1. Check out top attractions like Old Town Square and Royal Route, and jump on the metro at Staromestska Station or Staroměstská Stop to see more of the city.

Prague 2

Known for its ample dining options and fascinating museums, there's plenty to explore in Prague 2. You can visit top attractions like Peace Square and New Town Hall, and jump on the metro at Náměstí Míru Stop or Namesti Miru Station to see more of the city.

Top Prague 21 Hotel Reviews

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Frequently asked questions

What's it like in Prague 21?
Travellers will be sure to enjoy their time in Prague's Prague 21 neighbourhood.
If I need to cancel my hotel reservation in Prague 21, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and be given a refund within 24 hours of booking. Enter your dates, click on "Search", then filter by "fully refundable" to review the best deals available in Prague 21.
What can I see and do in this Prague neighbourhood?
Some places to visit in the Prague area include House of the Black Madonna, Na Prikope and Powder Tower so get out of the neighbourhood to explore more of the city. While you're out sightseeing, Municipal House Hall and Museum of Communism are a couple of sights to visit in the city.
How can I get around Prague 21 and the greater Prague area?
If you're considering venturing out of town, train travel is a great option. Prague-Klanovice Station is the closest train station, but Prague-Běchovice střed Station and Prague-Bechovice Station are also close by.