Otay Mesa Travel Guide
San Diego
Popular places to visit

San Diego Zoo
Why not visit the animals who live at San Diego Zoo and see why this is a popular attraction in San Diego? Stroll along the area's seaside or experience its fascinating museums.

San Diego Convention Center
During your trip, find out what's happening in San Diego Convention Center, a top convention centre in San Diego. Experience the area's fascinating museums and acclaimed art galleries.

Mission Bay
Explore the great outdoors at Mission Bay, a popular spot to commune with nature in San Diego. Stroll along the seaside in this family-friendly area or visit its top-notch restaurants.

SeaWorld
Make time to visit the sea life at SeaWorld, and find out why this is a popular attraction in San Diego. Discover the beautiful sunsets and top-notch restaurants in this walkable area.

Mission Beach
Nothing says holiday like spending a lazy day at Mission Beach, a popular beach in San Diego. Stroll along the seaside or discover the area's sunsets.

Petco Park
Catch an event at Petco Park during your trip to San Diego. Discover the top-notch restaurants and fascinating museums in this walkable area.
Top hotels in Otay Mesa

Reviewed on 30 Jun 2025

Reviewed on 30 Jun 2025

Reviewed on 29 Jun 2025

Reviewed on 30 Jun 2025

Reviewed on 1 Jul 2025

Reviewed on 30 Jun 2025
Other neighbourhoods around Otay Mesa

Mid-City
While you're in Mid-City, take in top sights like Cal Coast Credit Union Open Air Theater or Viejas Arena, and hop on the metro to see more of the city at SDSU Transit Center Station or Alvarado Station.

Gaslamp Quarter
Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Lyceum Theatre – discover Gaslamp Quarter, a destination also famous for its shopping.

Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Seaport Village and Petco Park are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

North Park
North Park is well liked for its restaurants, and you can visit sights like San Diego Zoo and San Diego Natural History Museum if you have time to explore the area.

Little Italy
Visitors to Little Italy love its captivating waterfront views, and you can check out Maritime Museum of San Diego and San Diego Bay. If you want to see more in the area, you can get around town on the metro at County Center - Little Italy Station.

Del Cerro
While there might not be top attractions in Del Cerro, you can explore the larger area and discover places like Cal Coast Credit Union Open Air Theater and Viejas Arena.
- Places of interest
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- Cross Border Xpress
- San Diego Zoo
- San Diego Convention Center
- Mission Bay
- Mission Beach
- San Ysidro Border Crossing
- Balboa Park
- Naval Base San Diego
- Port of San Diego
- USS Midway Museum
- Naval Base Coronado
- Seaport Village
- University of San Diego
- Las Americas Premium Outlets
- B Street Cruise Ship Terminal
- Sycuan Casino
- Old Town San Diego State Park
- Waterfront Park
- Shelter Island
- Snapdragon Stadium
- Belmont Park
- Fashion Valley Mall
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